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The map label for this gene is luxS

Identifier: 126208684

GI number: 126208684

Start: 1399250

End: 1399759

Strand: Reverse

Name: luxS

Synonym: APL_1216

Alternate gene names: 126208684

Gene position: 1399759-1399250 (Counterclockwise)

Preceding gene: 126208685

Following gene: 126208683

Centisome position: 61.54

GC content: 42.94

Gene sequence:

>510_bases
ATGCCTTTATTAGATAGCTTTAAAGTGGATCACACTCGTATGAACGCACCGGCAGTGCGTGTTGCAAAAACGATGACGAC
GCCGAAGGGCGATACGATTACCGTATTCGATTTACGTTTTTGCCGTCCGAATATTGATATTTTACCGGTGCGTGGTATCC
ACACGATGGAACACTTATTTGCCGGCTTTATGCGTGATCATTTAAATAGTGAAAGTGTAGAAATTATTGATATTTCGCCG
ATGGGTTGCCGTACCGGTTTCTATATGTCGTTAATCGGTGCGCCAAGCGAAGCGGATGTGGTTTCGGCGTGGACAAAATC
GATGGAAGATGCTTTAAATAAAGTACCGGACGTGTCAAAAATTCCGGAATTAAACGAATATCAATGCGGCTCTTATAAAG
AGCATTCGCTTGAAGAAGCGCATCAAATCGCTCGTGATGTGTTAGCCAAGGGTATCGGCGTAAACCGTAACGAAGATTTA
GCGCTTGATGAGAAATTATTAAATCCATAA

Upstream 100 bases:

>100_bases
GATTCCGCAAGAAGCGCCTGAATGGGATCAAGGAATCGCAGAATAATTTCAGATATGGGGTAATCACCTTACCCCTTTAA
GTTTTAAATTGGAGTAAAAA

Downstream 100 bases:

>100_bases
TCCTTCAAAAAGGCGTAATGTTTATTACGTCTTTTTCTTCTTAAAAATATATTTTAATCTTTGACAGACGCTTATGGCGT
CTTTTAGTTTTTTCAGGAAA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MPLLDSFKVDHTRMNAPAVRVAKTMTTPKGDTITVFDLRFCRPNIDILPVRGIHTMEHLFAGFMRDHLNSESVEIIDISP
MGCRTGFYMSLIGAPSEADVVSAWTKSMEDALNKVPDVSKIPELNEYQCGSYKEHSLEEAHQIARDVLAKGIGVNRNEDL
ALDEKLLNP

Sequences:

>Translated_169_residues
MPLLDSFKVDHTRMNAPAVRVAKTMTTPKGDTITVFDLRFCRPNIDILPVRGIHTMEHLFAGFMRDHLNSESVEIIDISP
MGCRTGFYMSLIGAPSEADVVSAWTKSMEDALNKVPDVSKIPELNEYQCGSYKEHSLEEAHQIARDVLAKGIGVNRNEDL
ALDEKLLNP
>Mature_168_residues
PLLDSFKVDHTRMNAPAVRVAKTMTTPKGDTITVFDLRFCRPNIDILPVRGIHTMEHLFAGFMRDHLNSESVEIIDISPM
GCRTGFYMSLIGAPSEADVVSAWTKSMEDALNKVPDVSKIPELNEYQCGSYKEHSLEEAHQIARDVLAKGIGVNRNEDLA
LDEKLLNP

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=167, Percent_Identity=70.059880239521, Blast_Score=245, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_ACTP2 (A3N1L8)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053909.1
- ProteinModelPortal:   A3N1L8
- SMR:   A3N1L8
- STRING:   A3N1L8
- GeneID:   4850390
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1216
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- PhylomeDB:   A3N1L8
- ProtClustDB:   PRK02260
- BioCyc:   APLE416269:APL_1216-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 18870; Mature: 18739

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFKVDHTRMNAPAVRVAKTMTTPKGDTITVFDLRFCRPNIDILPVRGIHTMEHLF
CCCCCCCCCCCHHCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEECCCHHHHHHHH
AGFMRDHLNSESVEIIDISPMGCRTGFYMSLIGAPSEADVVSAWTKSMEDALNKVPDVSK
HHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHH
IPELNEYQCGSYKEHSLEEAHQIARDVLAKGIGVNRNEDLALDEKLLNP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
PLLDSFKVDHTRMNAPAVRVAKTMTTPKGDTITVFDLRFCRPNIDILPVRGIHTMEHLF
CCCCCCCCCCHHCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEECCCHHHHHHHH
AGFMRDHLNSESVEIIDISPMGCRTGFYMSLIGAPSEADVVSAWTKSMEDALNKVPDVSK
HHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHH
IPELNEYQCGSYKEHSLEEAHQIARDVLAKGIGVNRNEDLALDEKLLNP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA