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The map label for this gene is argE [H]

Identifier: 126208557

GI number: 126208557

Start: 1255171

End: 1256313

Strand: Direct

Name: argE [H]

Synonym: APL_1085

Alternate gene names: 126208557

Gene position: 1255171-1256313 (Clockwise)

Preceding gene: 126208556

Following gene: 126208559

Centisome position: 55.18

GC content: 42.52

Gene sequence:

>1143_bases
ATGGCAAACACAAAGTTTATCGAACGTTACCGCAATTTAATTGCACTACCGACTATTTCTAGCTTGGAAGCGGCGGAAGA
TCAATCTAATAAGCAACTTATCGAATTATTGGCAACTTGGTTGGCGGATTTCGGCTTTAAAACCGAGATTATCCGAGTGG
AAGGCAGTCGTGATAAGTACAATTTATTAGCCACTTACGGCGAAGGTGAAGGCGGTTTATTATTAGCCGGTCATACCGAT
ACCGTACCGTTTGACGAAGGAAAATGGACATTTAATCCGTTTACCTTAACCGAACAAGACGGTAAATTCTACGGTTTAGG
TACAGCGGATATGAAAGGCTTTTTTGCATTTATTGTCGATGTAGTCAGCCAAATTGATTTAAACAAATTAACTAAACCGT
TACGTATCCTCGCAACAGCCGATGAAGAAACCACTATGCTTGGCGCCAGAACCTTCGCTCAACATACGCATATTCGCCCT
GATTGTGCGATTATCGGCGAGCCGACTTCTTTAAAACCGATTCGTGCGCATAAAGGGCACGTCGGCGAAGCGGTCAGAAT
TACCGGCAAAAGCGGTCACTCAAGCAATCCGGATCGCGGCATTAATGCGATTGAATTAATGCACCAAGCAACCGGCTATC
TGATGAATATGCGTAATCAATTACGTGAAAAATATCATAATGATCTGTTTAAAGTGCCGTATCCGACGATGAATTTCGGC
AATATCCACGGAGGTGATGCGATTAACCGTATTTGTGCCTGTTGTGAATTGCAATTTGATATGCGCCCATTGCCAAATCT
GCCGGTCGAAGATTTATATGCGATGGTCAATGAAAATCTAAAACCGATGTTGGAACAATACAGCGATCTGATTGAGATTC
GTCATTTACATGACGGAATTCCCGGCTATGAGTGTGAACATTCTGCACAAGTAGTACAAGTGGTTGAAAAACTGTTAGGC
GAAAAATGCGATGCGGTAAACTATTGTACCGAAGCACCGTTTATTCAACAGCTCTGCCCGACACTTGTTTTAGGTCCGGG
TTCTATCGAACAAGCACACCAGCCGGATGAATTTTTAGAAACAAAATTTATTGAGCCGACTCGTGAATTGCTCACTAAAA
TGATCCTACATTTTTGTGCTTAA

Upstream 100 bases:

>100_bases
TGACCCCGATACTTGAACGAGTAGCCATCTATGCGGTTATGATTTGGGAAATCCTAGCCGGTCTTGCAATGTTAAAACGT
AAATAAAAAGAGAAAATATT

Downstream 100 bases:

>100_bases
CAAGCGGTCGTTTTTCAAGGATTTTTTACAACAAAAAGGGAGCGATTAACGCTCCCTTTCTCATAACAGTTTCAAAATAC
TTAGAATTTGTAGCTAATAC

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MANTKFIERYRNLIALPTISSLEAAEDQSNKQLIELLATWLADFGFKTEIIRVEGSRDKYNLLATYGEGEGGLLLAGHTD
TVPFDEGKWTFNPFTLTEQDGKFYGLGTADMKGFFAFIVDVVSQIDLNKLTKPLRILATADEETTMLGARTFAQHTHIRP
DCAIIGEPTSLKPIRAHKGHVGEAVRITGKSGHSSNPDRGINAIELMHQATGYLMNMRNQLREKYHNDLFKVPYPTMNFG
NIHGGDAINRICACCELQFDMRPLPNLPVEDLYAMVNENLKPMLEQYSDLIEIRHLHDGIPGYECEHSAQVVQVVEKLLG
EKCDAVNYCTEAPFIQQLCPTLVLGPGSIEQAHQPDEFLETKFIEPTRELLTKMILHFCA

Sequences:

>Translated_380_residues
MANTKFIERYRNLIALPTISSLEAAEDQSNKQLIELLATWLADFGFKTEIIRVEGSRDKYNLLATYGEGEGGLLLAGHTD
TVPFDEGKWTFNPFTLTEQDGKFYGLGTADMKGFFAFIVDVVSQIDLNKLTKPLRILATADEETTMLGARTFAQHTHIRP
DCAIIGEPTSLKPIRAHKGHVGEAVRITGKSGHSSNPDRGINAIELMHQATGYLMNMRNQLREKYHNDLFKVPYPTMNFG
NIHGGDAINRICACCELQFDMRPLPNLPVEDLYAMVNENLKPMLEQYSDLIEIRHLHDGIPGYECEHSAQVVQVVEKLLG
EKCDAVNYCTEAPFIQQLCPTLVLGPGSIEQAHQPDEFLETKFIEPTRELLTKMILHFCA
>Mature_379_residues
ANTKFIERYRNLIALPTISSLEAAEDQSNKQLIELLATWLADFGFKTEIIRVEGSRDKYNLLATYGEGEGGLLLAGHTDT
VPFDEGKWTFNPFTLTEQDGKFYGLGTADMKGFFAFIVDVVSQIDLNKLTKPLRILATADEETTMLGARTFAQHTHIRPD
CAIIGEPTSLKPIRAHKGHVGEAVRITGKSGHSSNPDRGINAIELMHQATGYLMNMRNQLREKYHNDLFKVPYPTMNFGN
IHGGDAINRICACCELQFDMRPLPNLPVEDLYAMVNENLKPMLEQYSDLIEIRHLHDGIPGYECEHSAQVVQVVEKLLGE
KCDAVNYCTEAPFIQQLCPTLVLGPGSIEQAHQPDEFLETKFIEPTRELLTKMILHFCA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=374, Percent_Identity=64.9732620320856, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI1788816, Length=283, Percent_Identity=29.6819787985866, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789236, Length=222, Percent_Identity=26.5765765765766, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17551016, Length=334, Percent_Identity=26.6467065868263, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42641; Mature: 42510

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTKFIERYRNLIALPTISSLEAAEDQSNKQLIELLATWLADFGFKTEIIRVEGSRDKY
CCCHHHHHHHHHEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCE
NLLATYGEGEGGLLLAGHTDTVPFDEGKWTFNPFTLTEQDGKFYGLGTADMKGFFAFIVD
EEEEEECCCCCCEEEECCCCCCCCCCCCEEECCEEEECCCCCEEECCCHHHHHHHHHHHH
VVSQIDLNKLTKPLRILATADEETTMLGARTFAQHTHIRPDCAIIGEPTSLKPIRAHKGH
HHHHCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHCCCC
VGEAVRITGKSGHSSNPDRGINAIELMHQATGYLMNMRNQLREKYHNDLFKVPYPTMNFG
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
NIHGGDAINRICACCELQFDMRPLPNLPVEDLYAMVNENLKPMLEQYSDLIEIRHLHDGI
CCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
PGYECEHSAQVVQVVEKLLGEKCDAVNYCTEAPFIQQLCPTLVLGPGSIEQAHQPDEFLE
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHEEECCCCCCCCCCCHHHHH
TKFIEPTRELLTKMILHFCA
HHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANTKFIERYRNLIALPTISSLEAAEDQSNKQLIELLATWLADFGFKTEIIRVEGSRDKY
CCHHHHHHHHHEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCE
NLLATYGEGEGGLLLAGHTDTVPFDEGKWTFNPFTLTEQDGKFYGLGTADMKGFFAFIVD
EEEEEECCCCCCEEEECCCCCCCCCCCCEEECCEEEECCCCCEEECCCHHHHHHHHHHHH
VVSQIDLNKLTKPLRILATADEETTMLGARTFAQHTHIRPDCAIIGEPTSLKPIRAHKGH
HHHHCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHCCCC
VGEAVRITGKSGHSSNPDRGINAIELMHQATGYLMNMRNQLREKYHNDLFKVPYPTMNFG
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
NIHGGDAINRICACCELQFDMRPLPNLPVEDLYAMVNENLKPMLEQYSDLIEIRHLHDGI
CCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
PGYECEHSAQVVQVVEKLLGEKCDAVNYCTEAPFIQQLCPTLVLGPGSIEQAHQPDEFLE
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHEEECCCCCCCCCCCHHHHH
TKFIEPTRELLTKMILHFCA
HHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]