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The map label for this gene is leuE [H]

Identifier: 126208520

GI number: 126208520

Start: 1214449

End: 1215066

Strand: Direct

Name: leuE [H]

Synonym: APL_1046

Alternate gene names: 126208520

Gene position: 1214449-1215066 (Clockwise)

Preceding gene: 126208519

Following gene: 126208527

Centisome position: 53.39

GC content: 39.16

Gene sequence:

>618_bases
ATGAATGACATTGTAAATTATTGGGGATTTTTGACCGCTTGTATTTTACTGAACCTAACTCCGGGTTCCGATACGATTTA
TATTCTTACCCGTACGATTGCGGAGGGGAAAAAAGCCGGTTTAATGTCTTCATTCGGCATTTTAACTGGATTTTTTGTGC
ATATTTTAGCGGTATCGGTCGGCTTAGCACAGATTATCGCCCATTCGCCGACTCTATTTGCCGTACTAAAATATGCCGGC
GCCGGATATTTAGGTTGGCTCGGGATTAAAATGTGGAAACAACCGTTTTTAGTCCATCAAGTCAATTTGGATAAATTACC
GTTATGGCAAATTTATCGCCAAGGTCTAATCACTAATTTATTGAATCCGAAAGTAATTTTATTCTTTTTAGCCTTATTAC
CTCAGTTTGTTGCGACGAATGTAGAAAATACCTTTTTACCTTTTTTCTTACTTGGACTGACTTCACTTTCTACCACAACG
ATTTGGGTCATCATATTGGTTTTGGCGGCTTATCCGCTTGGTAATCTACTACGAAGCAATCCGAAAATAGGCGCGTCGAT
GAATAAAATCTGCGGAGCGATCTTCATTGCTTTGGCAATTAAAATAGGCTTGGAATAG

Upstream 100 bases:

>100_bases
TGATTGGCGAAGTATTGGATTCCAAATCCTATCTGCTGATGATTTGCTTGGCACTCGCGATCATATTATTAACCGTTGAT
AATTTTAGGCTGACTCGTAG

Downstream 100 bases:

>100_bases
CGATATATGCAAGCGGTTAAATTTTCCGGTTTTTTTGTAAAAAATCCCCGAGAGTTTGTCCACTTTCGGGGATTTTTTTA
TTAGAAAGTTACCTCTGCAG

Product: lysine exporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MNDIVNYWGFLTACILLNLTPGSDTIYILTRTIAEGKKAGLMSSFGILTGFFVHILAVSVGLAQIIAHSPTLFAVLKYAG
AGYLGWLGIKMWKQPFLVHQVNLDKLPLWQIYRQGLITNLLNPKVILFFLALLPQFVATNVENTFLPFFLLGLTSLSTTT
IWVIILVLAAYPLGNLLRSNPKIGASMNKICGAIFIALAIKIGLE

Sequences:

>Translated_205_residues
MNDIVNYWGFLTACILLNLTPGSDTIYILTRTIAEGKKAGLMSSFGILTGFFVHILAVSVGLAQIIAHSPTLFAVLKYAG
AGYLGWLGIKMWKQPFLVHQVNLDKLPLWQIYRQGLITNLLNPKVILFFLALLPQFVATNVENTFLPFFLLGLTSLSTTT
IWVIILVLAAYPLGNLLRSNPKIGASMNKICGAIFIALAIKIGLE
>Mature_205_residues
MNDIVNYWGFLTACILLNLTPGSDTIYILTRTIAEGKKAGLMSSFGILTGFFVHILAVSVGLAQIIAHSPTLFAVLKYAG
AGYLGWLGIKMWKQPFLVHQVNLDKLPLWQIYRQGLITNLLNPKVILFFLALLPQFVATNVENTFLPFFLLGLTSLSTTT
IWVIILVLAAYPLGNLLRSNPKIGASMNKICGAIFIALAIKIGLE

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=202, Percent_Identity=27.7227722772277, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI48994979, Length=198, Percent_Identity=33.8383838383838, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786522, Length=188, Percent_Identity=23.4042553191489, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22495; Mature: 22495

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIVNYWGFLTACILLNLTPGSDTIYILTRTIAEGKKAGLMSSFGILTGFFVHILAVSV
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
GLAQIIAHSPTLFAVLKYAGAGYLGWLGIKMWKQPFLVHQVNLDKLPLWQIYRQGLITNL
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHEEECCCCCCCHHHHHHHHHHHHH
LNPKVILFFLALLPQFVATNVENTFLPFFLLGLTSLSTTTIWVIILVLAAYPLGNLLRSN
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
PKIGASMNKICGAIFIALAIKIGLE
CCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDIVNYWGFLTACILLNLTPGSDTIYILTRTIAEGKKAGLMSSFGILTGFFVHILAVSV
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
GLAQIIAHSPTLFAVLKYAGAGYLGWLGIKMWKQPFLVHQVNLDKLPLWQIYRQGLITNL
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHEEECCCCCCCHHHHHHHHHHHHH
LNPKVILFFLALLPQFVATNVENTFLPFFLLGLTSLSTTTIWVIILVLAAYPLGNLLRSN
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
PKIGASMNKICGAIFIALAIKIGLE
CCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA