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The map label for this gene is yfbQ [C]

Identifier: 126208517

GI number: 126208517

Start: 1211431

End: 1212648

Strand: Direct

Name: yfbQ [C]

Synonym: APL_1043

Alternate gene names: 126208517

Gene position: 1211431-1212648 (Clockwise)

Preceding gene: 126208515

Following gene: 126208518

Centisome position: 53.26

GC content: 43.68

Gene sequence:

>1218_bases
ATGGAACGTTTCCCTAAATCAGACAAGCTCGCAAACGTTCGTTACGATATTCGTGGCGCAATACATAAAGAAGCTCTTCG
TTTAGAAGAAGAGGGTAATAAAATTTTAAAATTGAATATCGGTAATCCCGCCCCGTTTGGTTTTGAAGCCCCGGACGAAA
TAGTTGTCGATGTCATTCGCAATTTACCGAAATCGCAGGGTTATTGCGACTCCAAAGGCTTATATTCGGCACGTAAAGCG
ATCGTACAATATTATCAATCGAAAGGTATTCGTAACGTCGATGTCAATGACGTCTATATCGGTAACGGCGTATCGGAATT
AATTACAATGTCGATGCAAGCCTTGCTGAATGACGGCGACGAAATGTTAATTCCGATGCCGGATTACCCGCTTTGGACTG
CGGCGGCAACCCTTGCCGGCGGTAAAGCGGTGCATTATTTATGTGATGAAAACAATGAATGGATGCCGGATATTGAGGAT
ATTAAAGCGAAAATTACCCCTCGTACCAAAGGGATTTTAGTCATTAACCCGAATAATCCGACCGGTGCGGTTTACAGCCG
CTCGATGTTACTTGAGATTGCGGAAATCGCTCGCCAGCACAATTTAATGATTTTTGCGGACGAAATTTACGAGAAAATTA
TTTATGACGGAGCGGTACATCATCATATTGCCGCACTTGCACCGGATTTATTATGCGTAACCTATAACGGCTTATCGAAA
GCCTACCGTGTCGCCGGTTTCCGTCAAGGTTGGATGGTATTAAGCGGTCCGAAAAACCAAGCGAGAGGTTTTATTGAAGG
TTTGGATATGCTCGCTTCCATGCGTTTATGTGCGACAACCCCGATGCAGCACGCGATTCAAACGGCATTAGGCGGTTATC
AAAGTATCAACGAATTCGTATTGCCGGGCGGTCGTTTACTCGAACAACGTAATAAAATGTATGAGTTGTTGGTACAAATT
CCGGGAATTTCTTGTGTGAAAGCGAAAGGTGCGCTGTATATGTTCCCGAAAATTGACACGGAAATGTACGGTATCAAAGA
CGATGCCAAATTTATTTATGACTTATTACAGGCGGAAAGAGTGCTGTTAGTACAAGGTTCCGGCTTTAACTGGCACAAAC
CGGATCACTTCCGTGTCGTAACCTTGCCTTATGCGCACCAAATTGAAGAAGCATTAGGGCGTCTTGCCAACTTCTTAAAA
ACCTATAAACAATCTTAA

Upstream 100 bases:

>100_bases
TAGCTCATTTCCTCTTTAAATTCCTACTAAATCAGAGTAAAGTTTAACAATTTTCTCACTCTAATAACGATTTTCTTTCA
AACCAAACAGGACAAACACC

Downstream 100 bases:

>100_bases
TCTTTTCTCCGCCCCTATTGGGGCGGATTACGTCTTACCTATTATGCAACTCGGTATTATTTATTCGCTTTCCGCTTCCG
CACTATTCGGCGGAATGTAT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MERFPKSDKLANVRYDIRGAIHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEIVVDVIRNLPKSQGYCDSKGLYSARKA
IVQYYQSKGIRNVDVNDVYIGNGVSELITMSMQALLNDGDEMLIPMPDYPLWTAAATLAGGKAVHYLCDENNEWMPDIED
IKAKITPRTKGILVINPNNPTGAVYSRSMLLEIAEIARQHNLMIFADEIYEKIIYDGAVHHHIAALAPDLLCVTYNGLSK
AYRVAGFRQGWMVLSGPKNQARGFIEGLDMLASMRLCATTPMQHAIQTALGGYQSINEFVLPGGRLLEQRNKMYELLVQI
PGISCVKAKGALYMFPKIDTEMYGIKDDAKFIYDLLQAERVLLVQGSGFNWHKPDHFRVVTLPYAHQIEEALGRLANFLK
TYKQS

Sequences:

>Translated_405_residues
MERFPKSDKLANVRYDIRGAIHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEIVVDVIRNLPKSQGYCDSKGLYSARKA
IVQYYQSKGIRNVDVNDVYIGNGVSELITMSMQALLNDGDEMLIPMPDYPLWTAAATLAGGKAVHYLCDENNEWMPDIED
IKAKITPRTKGILVINPNNPTGAVYSRSMLLEIAEIARQHNLMIFADEIYEKIIYDGAVHHHIAALAPDLLCVTYNGLSK
AYRVAGFRQGWMVLSGPKNQARGFIEGLDMLASMRLCATTPMQHAIQTALGGYQSINEFVLPGGRLLEQRNKMYELLVQI
PGISCVKAKGALYMFPKIDTEMYGIKDDAKFIYDLLQAERVLLVQGSGFNWHKPDHFRVVTLPYAHQIEEALGRLANFLK
TYKQS
>Mature_405_residues
MERFPKSDKLANVRYDIRGAIHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEIVVDVIRNLPKSQGYCDSKGLYSARKA
IVQYYQSKGIRNVDVNDVYIGNGVSELITMSMQALLNDGDEMLIPMPDYPLWTAAATLAGGKAVHYLCDENNEWMPDIED
IKAKITPRTKGILVINPNNPTGAVYSRSMLLEIAEIARQHNLMIFADEIYEKIIYDGAVHHHIAALAPDLLCVTYNGLSK
AYRVAGFRQGWMVLSGPKNQARGFIEGLDMLASMRLCATTPMQHAIQTALGGYQSINEFVLPGGRLLEQRNKMYELLVQI
PGISCVKAKGALYMFPKIDTEMYGIKDDAKFIYDLLQAERVLLVQGSGFNWHKPDHFRVVTLPYAHQIEEALGRLANFLK
TYKQS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=388, Percent_Identity=27.319587628866, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI215599424, Length=378, Percent_Identity=26.7195767195767, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI19263340, Length=378, Percent_Identity=26.7195767195767, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI4885351, Length=446, Percent_Identity=24.6636771300448, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI56713254, Length=229, Percent_Identity=27.0742358078603, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI56713256, Length=237, Percent_Identity=27.0042194092827, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI95147551, Length=182, Percent_Identity=32.4175824175824, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI169881279, Length=182, Percent_Identity=32.4175824175824, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI169881281, Length=150, Percent_Identity=30, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=71.5346534653465, Blast_Score=628, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=399, Percent_Identity=25.8145363408521, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786816, Length=193, Percent_Identity=24.3523316062176, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=31.3513513513514, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71981209, Length=465, Percent_Identity=24.5161290322581, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=265, Percent_Identity=29.0566037735849, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=265, Percent_Identity=29.0566037735849, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=272, Percent_Identity=27.2058823529412, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71981215, Length=295, Percent_Identity=25.4237288135593, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=453, Percent_Identity=26.2693156732892, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323118, Length=349, Percent_Identity=26.9340974212034, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322401, Length=253, Percent_Identity=25.6916996047431, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI18859735, Length=411, Percent_Identity=30.6569343065693, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI45551451, Length=383, Percent_Identity=27.4151436031332, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24641770, Length=383, Percent_Identity=27.4151436031332, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24641760, Length=383, Percent_Identity=27.4151436031332, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24641768, Length=383, Percent_Identity=27.4151436031332, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24641766, Length=383, Percent_Identity=27.4151436031332, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24641764, Length=383, Percent_Identity=27.4151436031332, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28573069, Length=257, Percent_Identity=24.9027237354086, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646114, Length=257, Percent_Identity=24.9027237354086, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573067, Length=257, Percent_Identity=24.9027237354086, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573065, Length=257, Percent_Identity=24.9027237354086, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45415; Mature: 45415

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFPKSDKLANVRYDIRGAIHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEIVVDVIR
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
NLPKSQGYCDSKGLYSARKAIVQYYQSKGIRNVDVNDVYIGNGVSELITMSMQALLNDGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
EMLIPMPDYPLWTAAATLAGGKAVHYLCDENNEWMPDIEDIKAKITPRTKGILVINPNNP
CEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGAVYSRSMLLEIAEIARQHNLMIFADEIYEKIIYDGAVHHHIAALAPDLLCVTYNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCHHH
AYRVAGFRQGWMVLSGPKNQARGFIEGLDMLASMRLCATTPMQHAIQTALGGYQSINEFV
HHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRNKMYELLVQIPGISCVKAKGALYMFPKIDTEMYGIKDDAKFIYDLLQAER
CCCHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCCHHCCCCHHHHHHHHHHHCCE
VLLVQGSGFNWHKPDHFRVVTLPYAHQIEEALGRLANFLKTYKQS
EEEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERFPKSDKLANVRYDIRGAIHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEIVVDVIR
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
NLPKSQGYCDSKGLYSARKAIVQYYQSKGIRNVDVNDVYIGNGVSELITMSMQALLNDGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
EMLIPMPDYPLWTAAATLAGGKAVHYLCDENNEWMPDIEDIKAKITPRTKGILVINPNNP
CEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGAVYSRSMLLEIAEIARQHNLMIFADEIYEKIIYDGAVHHHIAALAPDLLCVTYNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCHHH
AYRVAGFRQGWMVLSGPKNQARGFIEGLDMLASMRLCATTPMQHAIQTALGGYQSINEFV
HHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRNKMYELLVQIPGISCVKAKGALYMFPKIDTEMYGIKDDAKFIYDLLQAER
CCCHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCCHHCCCCHHHHHHHHHHHCCE
VLLVQGSGFNWHKPDHFRVVTLPYAHQIEEALGRLANFLKTYKQS
EEEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]