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The map label for this gene is hemY [H]

Identifier: 126208481

GI number: 126208481

Start: 1170661

End: 1171911

Strand: Reverse

Name: hemY [H]

Synonym: APL_1007

Alternate gene names: 126208481

Gene position: 1171911-1170661 (Counterclockwise)

Preceding gene: 126208482

Following gene: 126208477

Centisome position: 51.52

GC content: 39.65

Gene sequence:

>1251_bases
ATGTTTAGAGTGCTTTTTTTAATGCTTTTATTACTGGCGAGTTTAATTTTCGGCCCTTATCTTTCCGGTAATCAAGGTTA
CGTTCGTATTGAAACCGATACGAAGGTAATCGAAATGAGCTTGGTAATGTTAGTAGTCTTCTTTGTGATTGCAATGGCGG
TGGTTTATTCGATTGAAGTCATTATTAGTCGTTTTTGTCGCTTAAGCAAAGGCTCGTATAACTGGTTCTTTAACCGTAAA
CATAAAAAAGCCCAGCAAGAAACCTTAGAAGGGTTAATGCGAATGAGCGAAGGCGATTATTCTAAAGCGGAAAAATTATT
TAGTAAGAATGCAAAACATGCGGACGAGCCCGTTTTAAATCTGATTAAAGCGGCCGAAGCGGCACAACAAGGCGGTGATG
AATTCAATGCGAATAAATATTTAATTGAAGCGGCGGAATTAGCCGGACCGAATAATGTTGCGGTGGAATTAGCCCGAACC
CGTATTTTAGTTCAACAAAATAAACTGCCGGCGGCTCGTAGTGCGATTGACAGTTTAATTGAATTAGCTCCTCGTAATAC
GGAAGTATTGCGTTTAGCGATTAACATTTATAAAGACTCGAAAGCATATAACGCTTTAGACGGTATTTTAGAAGATATTG
GACAACGTAGTTTCCTTTCTGCAGAAGAATACGATGCATTAACGCACTTTGTTGATGACGGTTTACTTGATGAAAAAATG
AATGAGGAAGGACAAGACGGTTTATTGGCATGGTGGGAAAATCAACCGAGCCGTCGCCGTAAATCCATTTATGTTCGTAC
CGGTTTAGTCAAACGCTTAATTGATACCGATGATCATGAGTCCGCTCAAGAGATTGCACTGGAAACCGTGAAAAAATATG
AAGATGATCAGTTGGTACTGCTACTTGAACAACTTACTCGTTTACAAGTTGCTGAAGAAAGTAAATTGGTAAAACTGTTG
GTTAAGCGAGCGGATAAAGCCGATGCGCAATATACTGACGATTATGCAAGAGCGTTAGGTTATATCTATACCCGAGAAGG
ATTATTTGAGAAAGCGAAAAATTATTTCGCTCAATTGATCGAACATCGTGAGTGTGTTGCAAACGATAGAATTATGGCGC
TTCACGTTGCGGAGCAAATCGGTGATGTGGAGTTGGCGAGTAAAATCCGCGAGCTTAATTTGAAACAAGTAAGTATGGAT
AAGAAAAGCGAACCTGAGCCGAATGTTGCGTTAATTGAAAAATCCGTATAA

Upstream 100 bases:

>100_bases
CTCAACCGGCTACCGAAACAAAAGAGGAGCCGGTACCGCAACAACCCGTTCAGCCCCAAACTGAACAACCGTCTTCAGTT
GCACAGTAAGGAGGATAGCG

Downstream 100 bases:

>100_bases
TTCGGACGATAAAAAAGCCGTTTATCGAAAGATAAGCGGCTTTTTTGCGGGTATGAATTAGTGCTTTTTACCGAATAGTT
TCATTAACGGTAAAATAATT

Product: HemY-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MFRVLFLMLLLLASLIFGPYLSGNQGYVRIETDTKVIEMSLVMLVVFFVIAMAVVYSIEVIISRFCRLSKGSYNWFFNRK
HKKAQQETLEGLMRMSEGDYSKAEKLFSKNAKHADEPVLNLIKAAEAAQQGGDEFNANKYLIEAAELAGPNNVAVELART
RILVQQNKLPAARSAIDSLIELAPRNTEVLRLAINIYKDSKAYNALDGILEDIGQRSFLSAEEYDALTHFVDDGLLDEKM
NEEGQDGLLAWWENQPSRRRKSIYVRTGLVKRLIDTDDHESAQEIALETVKKYEDDQLVLLLEQLTRLQVAEESKLVKLL
VKRADKADAQYTDDYARALGYIYTREGLFEKAKNYFAQLIEHRECVANDRIMALHVAEQIGDVELASKIRELNLKQVSMD
KKSEPEPNVALIEKSV

Sequences:

>Translated_416_residues
MFRVLFLMLLLLASLIFGPYLSGNQGYVRIETDTKVIEMSLVMLVVFFVIAMAVVYSIEVIISRFCRLSKGSYNWFFNRK
HKKAQQETLEGLMRMSEGDYSKAEKLFSKNAKHADEPVLNLIKAAEAAQQGGDEFNANKYLIEAAELAGPNNVAVELART
RILVQQNKLPAARSAIDSLIELAPRNTEVLRLAINIYKDSKAYNALDGILEDIGQRSFLSAEEYDALTHFVDDGLLDEKM
NEEGQDGLLAWWENQPSRRRKSIYVRTGLVKRLIDTDDHESAQEIALETVKKYEDDQLVLLLEQLTRLQVAEESKLVKLL
VKRADKADAQYTDDYARALGYIYTREGLFEKAKNYFAQLIEHRECVANDRIMALHVAEQIGDVELASKIRELNLKQVSMD
KKSEPEPNVALIEKSV
>Mature_416_residues
MFRVLFLMLLLLASLIFGPYLSGNQGYVRIETDTKVIEMSLVMLVVFFVIAMAVVYSIEVIISRFCRLSKGSYNWFFNRK
HKKAQQETLEGLMRMSEGDYSKAEKLFSKNAKHADEPVLNLIKAAEAAQQGGDEFNANKYLIEAAELAGPNNVAVELART
RILVQQNKLPAARSAIDSLIELAPRNTEVLRLAINIYKDSKAYNALDGILEDIGQRSFLSAEEYDALTHFVDDGLLDEKM
NEEGQDGLLAWWENQPSRRRKSIYVRTGLVKRLIDTDDHESAQEIALETVKKYEDDQLVLLLEQLTRLQVAEESKLVKLL
VKRADKADAQYTDDYARALGYIYTREGLFEKAKNYFAQLIEHRECVANDRIMALHVAEQIGDVELASKIRELNLKQVSMD
KKSEPEPNVALIEKSV

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790234, Length=309, Percent_Identity=37.8640776699029, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR011990 [H]

Pfam domain/function: PF07219 HemY_N [H]

EC number: NA

Molecular weight: Translated: 47277; Mature: 47277

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRVLFLMLLLLASLIFGPYLSGNQGYVRIETDTKVIEMSLVMLVVFFVIAMAVVYSIEV
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IISRFCRLSKGSYNWFFNRKHKKAQQETLEGLMRMSEGDYSKAEKLFSKNAKHADEPVLN
HHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHH
LIKAAEAAQQGGDEFNANKYLIEAAELAGPNNVAVELARTRILVQQNKLPAARSAIDSLI
HHHHHHHHHHCCCCCCCCHHEEEHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ELAPRNTEVLRLAINIYKDSKAYNALDGILEDIGQRSFLSAEEYDALTHFVDDGLLDEKM
HHCCCCHHHEEHHHHHHHCCHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHCCHHHHHC
NEEGQDGLLAWWENQPSRRRKSIYVRTGLVKRLIDTDDHESAQEIALETVKKYEDDQLVL
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHH
LLEQLTRLQVAEESKLVKLLVKRADKADAQYTDDYARALGYIYTREGLFEKAKNYFAQLI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHRECVANDRIMALHVAEQIGDVELASKIRELNLKQVSMDKKSEPEPNVALIEKSV
HHHHHHCCCCEEEEHHHHHHCCHHHHHHHHHCCHHHHCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MFRVLFLMLLLLASLIFGPYLSGNQGYVRIETDTKVIEMSLVMLVVFFVIAMAVVYSIEV
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IISRFCRLSKGSYNWFFNRKHKKAQQETLEGLMRMSEGDYSKAEKLFSKNAKHADEPVLN
HHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHH
LIKAAEAAQQGGDEFNANKYLIEAAELAGPNNVAVELARTRILVQQNKLPAARSAIDSLI
HHHHHHHHHHCCCCCCCCHHEEEHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ELAPRNTEVLRLAINIYKDSKAYNALDGILEDIGQRSFLSAEEYDALTHFVDDGLLDEKM
HHCCCCHHHEEHHHHHHHCCHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHCCHHHHHC
NEEGQDGLLAWWENQPSRRRKSIYVRTGLVKRLIDTDDHESAQEIALETVKKYEDDQLVL
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHH
LLEQLTRLQVAEESKLVKLLVKRADKADAQYTDDYARALGYIYTREGLFEKAKNYFAQLI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHRECVANDRIMALHVAEQIGDVELASKIRELNLKQVSMDKKSEPEPNVALIEKSV
HHHHHHCCCCEEEEHHHHHHCCHHHHHHHHHCCHHHHCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]