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The map label for this gene is hscB [H]

Identifier: 126208404

GI number: 126208404

Start: 1070318

End: 1070839

Strand: Reverse

Name: hscB [H]

Synonym: APL_0928

Alternate gene names: 126208404

Gene position: 1070839-1070318 (Counterclockwise)

Preceding gene: 126208405

Following gene: 126208403

Centisome position: 47.08

GC content: 39.46

Gene sequence:

>522_bases
ATGAATAATCCTTTTGCACTATTTGATTTACCGGTTCAATTTGAATTGGATAACGCGCTACTTTCCGAACGCTATTTGGC
ATTGCAAAGACAACTGCATCCGGATAATTTTGCGAACGGTTCTTCAACGGAACAATTAGCGGCGGTACAAAAATCGGCAG
ATATAAATTCAGCGTTACAAACGCTTAAAGATCCGATTCTACGTGCGGAAGCAATAATTGAAATTCATACCGGCGAAGCA
AAAAATCTCGAAGAAAAAAGTATGCGAGATATCGAGTTCTTAATGCAACAGATGGAGTGGCATGAGAAACTGGAAACAAT
AGAGCATCGTCATGATGAAGCTGAATTAACCGCCTTTCTAAAGCAAATTAAAACCGAACAGAAAGCCGTTTTAGAGCAAC
TGCAACAAACGCTGGAAGCGCAACAATGGCAACAAGCCAATGGGCTGACCGATCGCTTACGCTATTTTAAAAAGCTGATT
ATTCAAATCGAAAAAGTCGAAGAAAAATTCTTTGATATGTAG

Upstream 100 bases:

>100_bases
TTTCGTCAAAGAAGGTTTAAACGAAGGTTTTAAATATAACAATCCGAATGTGAAAGATTCTTGCGGCTGTGGTGAAAGTT
TTAACGTATAGAGATAAACA

Downstream 100 bases:

>100_bases
CGGTATCGGCCGCATACAAGCGGTCTGATTTTAAGAGAATTTTGCAAATGGCTTTACCCTATATTTTATTGGCACTGGTC
GCCGGTTCCGCTCTGGCAAG

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MNNPFALFDLPVQFELDNALLSERYLALQRQLHPDNFANGSSTEQLAAVQKSADINSALQTLKDPILRAEAIIEIHTGEA
KNLEEKSMRDIEFLMQQMEWHEKLETIEHRHDEAELTAFLKQIKTEQKAVLEQLQQTLEAQQWQQANGLTDRLRYFKKLI
IQIEKVEEKFFDM

Sequences:

>Translated_173_residues
MNNPFALFDLPVQFELDNALLSERYLALQRQLHPDNFANGSSTEQLAAVQKSADINSALQTLKDPILRAEAIIEIHTGEA
KNLEEKSMRDIEFLMQQMEWHEKLETIEHRHDEAELTAFLKQIKTEQKAVLEQLQQTLEAQQWQQANGLTDRLRYFKKLI
IQIEKVEEKFFDM
>Mature_173_residues
MNNPFALFDLPVQFELDNALLSERYLALQRQLHPDNFANGSSTEQLAAVQKSADINSALQTLKDPILRAEAIIEIHTGEA
KNLEEKSMRDIEFLMQQMEWHEKLETIEHRHDEAELTAFLKQIKTEQKAVLEQLQQTLEAQQWQQANGLTDRLRYFKKLI
IQIEKVEEKFFDM

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=168, Percent_Identity=31.547619047619, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1788876, Length=173, Percent_Identity=43.3526011560694, Blast_Score=132, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20253; Mature: 20253

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPFALFDLPVQFELDNALLSERYLALQRQLHPDNFANGSSTEQLAAVQKSADINSALQ
CCCCCEEEECCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TLKDPILRAEAIIEIHTGEAKNLEEKSMRDIEFLMQQMEWHEKLETIEHRHDEAELTAFL
HHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KQIKTEQKAVLEQLQQTLEAQQWQQANGLTDRLRYFKKLIIQIEKVEEKFFDM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNPFALFDLPVQFELDNALLSERYLALQRQLHPDNFANGSSTEQLAAVQKSADINSALQ
CCCCCEEEECCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TLKDPILRAEAIIEIHTGEAKNLEEKSMRDIEFLMQQMEWHEKLETIEHRHDEAELTAFL
HHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KQIKTEQKAVLEQLQQTLEAQQWQQANGLTDRLRYFKKLIIQIEKVEEKFFDM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA