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The map label for this gene is yggW [C]

Identifier: 126208323

GI number: 126208323

Start: 981993

End: 983150

Strand: Reverse

Name: yggW [C]

Synonym: APL_0847

Alternate gene names: 126208323

Gene position: 983150-981993 (Counterclockwise)

Preceding gene: 126208329

Following gene: 126208322

Centisome position: 43.23

GC content: 43.78

Gene sequence:

>1158_bases
GTGAATTTAGCCCTTCCTCCCTTAAGTCTTTATATCCATATTCCGTGGTGCGTACAAAAATGTCCGTACTGCGATTTCAA
TTCACATGCGCAAAAAGGTGTGATTCCGGAAGCGGAATATATTCAACATCTACTTGCAGATTTATCGCAAGATTTGACCG
CTTATCAGCTGGCAATCGGTAATCGCAAAATTCATTCGATTTTTATTGGCGGCGGTACGCCAAGTCTGTTTTCGGCAGAA
GGGATTGCTTATCTGTTGGCAGAAGTCGAAAAGCGTATTCCGTTTGAAGAGCATATCGAAATTACCCTTGAGGCAAATCC
CGGTACGGCGGAAGCGGAGCGTTTTCTTGGCTATGCACAAGGCGGTGTAACACGTATCTCAATGGGGATCCAAAGTTTCG
AGCCGGAAAAACTGCTCAAACTTGGACGTATTCACGACTCGAATGAGGCGAAACAAGCGGTCATTTTTGCGCAAAATTCT
GCAAAATCCGGTTTGCAAAGTTTTAATATCGACTTAATGCACGGCTTACCGAATCAATCGGTGGCACAAGCACTGGACGA
TTTACGACAGGGGATTGCGCTCGCACCACCGCATTTGTCGTGGTATCAATTAACCATTGAGCCGAACACGATGTTCTATT
ACCGTCAGCCGACTTTACCGGACGACGATGAATTATGGGATATTTTCGAGCAAGGTCATCAGTTACTCACCGCTGCCGGC
TATGAACAATATGAAACTTCGGCTTATGCGAAAAAAGGTTATCAATGCCGTCATAATCTCAATTATTGGCGTTTTGGCGA
CTATTTGGCGATTGGTTGCGGAGCGCACGGTAAGATTAGTTATCCGACCGGCGAAATTTACCGCTTCAGCAAAACCAAAC
ACCCGAAAGGTTATATGCGAGGTGAATATCGTTACAGCCAAGATTTGATTGAGCTTGCTGATCGTCCGTTTGAATTTTTT
ATGAATCGTTTCCGCTTATTGGAAGCGACCCCAAAACAAGAATTTGAGTTCTACACCGGTCTTGATCGTGAAATCGTTAG
ACCAACAGTGGATTGGGCATTAAGCAAAAATTACATCATGGAAACCGAAAAACATTGGCAGATTACCCAGCACGGTAAGT
TGTTTTTAAATGAATTATTGGAAGGTTTTTTAGAATAG

Upstream 100 bases:

>100_bases
CTCTAATGTTAGATTTGTGATCTCTCTCACAGAAAACTTTTCTTTCCTGTTTACGGACTTTTCGTTATCATCATTTTTAT
TTAATGATAGTAGTTAGAAC

Downstream 100 bases:

>100_bases
CTTTTGCAAAAAAATTCAAAGATTTGACCGCTTGTAGTAGAATACAAGCGGTCTTTTTTTAGGAATTTTTTGCAATGAAT
ACACTTAAAGCAGGCGATAA

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNLALPPLSLYIHIPWCVQKCPYCDFNSHAQKGVIPEAEYIQHLLADLSQDLTAYQLAIGNRKIHSIFIGGGTPSLFSAE
GIAYLLAEVEKRIPFEEHIEITLEANPGTAEAERFLGYAQGGVTRISMGIQSFEPEKLLKLGRIHDSNEAKQAVIFAQNS
AKSGLQSFNIDLMHGLPNQSVAQALDDLRQGIALAPPHLSWYQLTIEPNTMFYYRQPTLPDDDELWDIFEQGHQLLTAAG
YEQYETSAYAKKGYQCRHNLNYWRFGDYLAIGCGAHGKISYPTGEIYRFSKTKHPKGYMRGEYRYSQDLIELADRPFEFF
MNRFRLLEATPKQEFEFYTGLDREIVRPTVDWALSKNYIMETEKHWQITQHGKLFLNELLEGFLE

Sequences:

>Translated_385_residues
MNLALPPLSLYIHIPWCVQKCPYCDFNSHAQKGVIPEAEYIQHLLADLSQDLTAYQLAIGNRKIHSIFIGGGTPSLFSAE
GIAYLLAEVEKRIPFEEHIEITLEANPGTAEAERFLGYAQGGVTRISMGIQSFEPEKLLKLGRIHDSNEAKQAVIFAQNS
AKSGLQSFNIDLMHGLPNQSVAQALDDLRQGIALAPPHLSWYQLTIEPNTMFYYRQPTLPDDDELWDIFEQGHQLLTAAG
YEQYETSAYAKKGYQCRHNLNYWRFGDYLAIGCGAHGKISYPTGEIYRFSKTKHPKGYMRGEYRYSQDLIELADRPFEFF
MNRFRLLEATPKQEFEFYTGLDREIVRPTVDWALSKNYIMETEKHWQITQHGKLFLNELLEGFLE
>Mature_385_residues
MNLALPPLSLYIHIPWCVQKCPYCDFNSHAQKGVIPEAEYIQHLLADLSQDLTAYQLAIGNRKIHSIFIGGGTPSLFSAE
GIAYLLAEVEKRIPFEEHIEITLEANPGTAEAERFLGYAQGGVTRISMGIQSFEPEKLLKLGRIHDSNEAKQAVIFAQNS
AKSGLQSFNIDLMHGLPNQSVAQALDDLRQGIALAPPHLSWYQLTIEPNTMFYYRQPTLPDDDELWDIFEQGHQLLTAAG
YEQYETSAYAKKGYQCRHNLNYWRFGDYLAIGCGAHGKISYPTGEIYRFSKTKHPKGYMRGEYRYSQDLIELADRPFEFF
MNRFRLLEATPKQEFEFYTGLDREIVRPTVDWALSKNYIMETEKHWQITQHGKLFLNELLEGFLE

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=274, Percent_Identity=34.3065693430657, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI1789325, Length=382, Percent_Identity=63.8743455497382, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI87082341, Length=407, Percent_Identity=25.0614250614251, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44150; Mature: 44150

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLALPPLSLYIHIPWCVQKCPYCDFNSHAQKGVIPEAEYIQHLLADLSQDLTAYQLAIG
CCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHEEEHEEC
NRKIHSIFIGGGTPSLFSAEGIAYLLAEVEKRIPFEEHIEITLEANPGTAEAERFLGYAQ
CCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHC
GGVTRISMGIQSFEPEKLLKLGRIHDSNEAKQAVIFAQNSAKSGLQSFNIDLMHGLPNQS
CCCEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCHHCCHHHCCEEEECCCCCHH
VAQALDDLRQGIALAPPHLSWYQLTIEPNTMFYYRQPTLPDDDELWDIFEQGHQLLTAAG
HHHHHHHHHCCCEECCCCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
YEQYETSAYAKKGYQCRHNLNYWRFGDYLAIGCGAHGKISYPTGEIYRFSKTKHPKGYMR
CHHHHHHHHHHCCCHHHCCCCEEEECCEEEEECCCCCEEECCCCCEEEECCCCCCCCCCC
GEYRYSQDLIELADRPFEFFMNRFRLLEATPKQEFEFYTGLDREIVRPTVDWALSKNYIM
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEE
ETEKHWQITQHGKLFLNELLEGFLE
CCCCCEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLALPPLSLYIHIPWCVQKCPYCDFNSHAQKGVIPEAEYIQHLLADLSQDLTAYQLAIG
CCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHEEEHEEC
NRKIHSIFIGGGTPSLFSAEGIAYLLAEVEKRIPFEEHIEITLEANPGTAEAERFLGYAQ
CCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHC
GGVTRISMGIQSFEPEKLLKLGRIHDSNEAKQAVIFAQNSAKSGLQSFNIDLMHGLPNQS
CCCEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCHHCCHHHCCEEEECCCCCHH
VAQALDDLRQGIALAPPHLSWYQLTIEPNTMFYYRQPTLPDDDELWDIFEQGHQLLTAAG
HHHHHHHHHCCCEECCCCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
YEQYETSAYAKKGYQCRHNLNYWRFGDYLAIGCGAHGKISYPTGEIYRFSKTKHPKGYMR
CHHHHHHHHHHCCCHHHCCCCEEEECCEEEEECCCCCEEECCCCCEEEECCCCCCCCCCC
GEYRYSQDLIELADRPFEFFMNRFRLLEATPKQEFEFYTGLDREIVRPTVDWALSKNYIM
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEE
ETEKHWQITQHGKLFLNELLEGFLE
CCCCCEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]