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The map label for this gene is gmhB [H]

Identifier: 126208321

GI number: 126208321

Start: 980900

End: 981445

Strand: Reverse

Name: gmhB [H]

Synonym: APL_0845

Alternate gene names: 126208321

Gene position: 981445-980900 (Counterclockwise)

Preceding gene: 126208322

Following gene: 126208320

Centisome position: 43.15

GC content: 42.12

Gene sequence:

>546_bases
GTGAAAAAGGCGATATTTTTAGATCGTGACGGCACAATTAATATTGATCACGGTTATGTACATCAAATTGACGACTTTCA
ATTTATTGAAGGTGTCGGCAAGGCGTTAAAGCAGCTACAAGATAAAGGCTATCTGTTGGTATTGGTCACCAATCAATCCG
GTATTGCGCGCGGTTATTTTAGTGAAGAGCAGTTTAACCAATTAACGGAGTGGATGGATTGGTCGCTGGATGAAGACTAC
GGCGTTGTGTTAGACGGTATCTATTATTGCCCTCATCATCCGGAAGGCAAAGGCGAATATAAAGAAGATTGCGATTGTCG
CAAACCGAAAGCAGGAATGTTTACTCAAGCGATTGCCGATTTGGATATTGATCCGGCACAATCGTATATGGTCGGTGATA
AATTAGAAGATCTGTTAGCGGCTGAAGTTGCCGGTGTGAAAACAAAAGTGTTAGTGCGAACAGGCAAACCTGTTACCGCA
GAAGGCGAAGCGAAAGCCGATTTGGTATTAGACAGCTTAGTGGATTTAGTCCGTTATATTAAATAA

Upstream 100 bases:

>100_bases
TAGTGAATGAACAGGGCGTGATCGAGCAGGTATTCGATAAATTCAAAACCGGTGAACACCATCAAATAGTAGTCGATTTT
GTAAAAGGAACGAAGTAATA

Downstream 100 bases:

>100_bases
TAAAGAAAGAAGATGAACTACAACGATAAATCATTATCTGCTCTGAAATTAGGGCAAAAAACCGAATATAAAAGTGAATA
TGATCCTACGCTTTTACAGC

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKKAIFLDRDGTINIDHGYVHQIDDFQFIEGVGKALKQLQDKGYLLVLVTNQSGIARGYFSEEQFNQLTEWMDWSLDEDY
GVVLDGIYYCPHHPEGKGEYKEDCDCRKPKAGMFTQAIADLDIDPAQSYMVGDKLEDLLAAEVAGVKTKVLVRTGKPVTA
EGEAKADLVLDSLVDLVRYIK

Sequences:

>Translated_181_residues
MKKAIFLDRDGTINIDHGYVHQIDDFQFIEGVGKALKQLQDKGYLLVLVTNQSGIARGYFSEEQFNQLTEWMDWSLDEDY
GVVLDGIYYCPHHPEGKGEYKEDCDCRKPKAGMFTQAIADLDIDPAQSYMVGDKLEDLLAAEVAGVKTKVLVRTGKPVTA
EGEAKADLVLDSLVDLVRYIK
>Mature_181_residues
MKKAIFLDRDGTINIDHGYVHQIDDFQFIEGVGKALKQLQDKGYLLVLVTNQSGIARGYFSEEQFNQLTEWMDWSLDEDY
GVVLDGIYYCPHHPEGKGEYKEDCDCRKPKAGMFTQAIADLDIDPAQSYMVGDKLEDLLAAEVAGVKTKVLVRTGKPVTA
EGEAKADLVLDSLVDLVRYIK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=179, Percent_Identity=65.3631284916201, Blast_Score=235, Evalue=1e-63,
Organism=Escherichia coli, GI87082027, Length=148, Percent_Identity=35.1351351351351, Blast_Score=87, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20296; Mature: 20296

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAIFLDRDGTINIDHGYVHQIDDFQFIEGVGKALKQLQDKGYLLVLVTNQSGIARGYF
CCCEEEECCCCEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC
SEEQFNQLTEWMDWSLDEDYGVVLDGIYYCPHHPEGKGEYKEDCDCRKPKAGMFTQAIAD
CHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHC
LDIDPAQSYMVGDKLEDLLAAEVAGVKTKVLVRTGKPVTAEGEAKADLVLDSLVDLVRYI
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHC
K
C
>Mature Secondary Structure
MKKAIFLDRDGTINIDHGYVHQIDDFQFIEGVGKALKQLQDKGYLLVLVTNQSGIARGYF
CCCEEEECCCCEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC
SEEQFNQLTEWMDWSLDEDYGVVLDGIYYCPHHPEGKGEYKEDCDCRKPKAGMFTQAIAD
CHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHC
LDIDPAQSYMVGDKLEDLLAAEVAGVKTKVLVRTGKPVTAEGEAKADLVLDSLVDLVRYI
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12101286 [H]