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The map label for this gene is dcd

Identifier: 126208311

GI number: 126208311

Start: 968300

End: 968884

Strand: Direct

Name: dcd

Synonym: APL_0835

Alternate gene names: 126208311

Gene position: 968300-968884 (Clockwise)

Preceding gene: 126208310

Following gene: 126208313

Centisome position: 42.57

GC content: 44.27

Gene sequence:

>585_bases
ATGCGCTTATGTGATACCGATATCGAACGTTATTTAGACGAAGGGATTATTGAAATAATTCCCCGCCCTTCAAATGAAAA
AATTACCGGCGCAACGGTTGATGTGCGTTTAGGTAATTCTTTCCGCGTCTTTCGTGAACACGCCACACCTTATATAGATT
TAAGTGGCCCTCGTGAAGAAGTGACCGCGCAGCTTCACAAAGTGATGAGTGAGGAAATTATTATCGCCGACGGCGAAGCC
TTTTTCTTACATCCGGGTGAATTGGCACTTGCCACGACATTAGAATCGGTTACTTTACCGGATAATGTCGTCGGCTGGTT
AGACGGTCGTTCCTCTTTAGCTCGCTTAGGTTTAATGGTACACGTAACGGCACACCGAATCGATCCGGGTTGGCAAGGTA
AAATCGTATTGGAATTTTTCAATGCCGGTAAATTACCGCTTGCTCTACGTCCTAATATGGCAATTGGCGCATTAAGTTTC
GAAATTCTAAGCGGTCATGCGGCAAAACCTTATAATGCCCGTAAAGACGCCAAATATAAAAACCAGCAAAGTGCGGTTTC
CAGCCGAATTAATCAAGATGATTAG

Upstream 100 bases:

>100_bases
ATGCGGATATTATCGTCCCGAAAGGCGGTAAAAACCGTATTGCGATCAATATTTTAAAAGCTCAAATTAAACAGTTATTA
TCTAAACGATAGGATTTACT

Downstream 100 bases:

>100_bases
CAGATTTTTACCAGTTTTCGGCATAGTAGTACAGTTGTACTTACTATGCCGAAAACGACCTCTGTGCATCATCCCATATT
AAAAAACGATAACACATCCT

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MRLCDTDIERYLDEGIIEIIPRPSNEKITGATVDVRLGNSFRVFREHATPYIDLSGPREEVTAQLHKVMSEEIIIADGEA
FFLHPGELALATTLESVTLPDNVVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFFNAGKLPLALRPNMAIGALSF
EILSGHAAKPYNARKDAKYKNQQSAVSSRINQDD

Sequences:

>Translated_194_residues
MRLCDTDIERYLDEGIIEIIPRPSNEKITGATVDVRLGNSFRVFREHATPYIDLSGPREEVTAQLHKVMSEEIIIADGEA
FFLHPGELALATTLESVTLPDNVVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFFNAGKLPLALRPNMAIGALSF
EILSGHAAKPYNARKDAKYKNQQSAVSSRINQDD
>Mature_194_residues
MRLCDTDIERYLDEGIIEIIPRPSNEKITGATVDVRLGNSFRVFREHATPYIDLSGPREEVTAQLHKVMSEEIIIADGEA
FFLHPGELALATTLESVTLPDNVVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFFNAGKLPLALRPNMAIGALSF
EILSGHAAKPYNARKDAKYKNQQSAVSSRINQDD

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=193, Percent_Identity=73.5751295336787, Blast_Score=299, Evalue=7e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_ACTP2 (A3N0J5)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053536.1
- ProteinModelPortal:   A3N0J5
- SMR:   A3N0J5
- STRING:   A3N0J5
- GeneID:   4849342
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0835
- eggNOG:   COG0717
- HOGENOM:   HBG553199
- OMA:   FSGHVTL
- PhylomeDB:   A3N0J5
- ProtClustDB:   PRK00416
- BioCyc:   APLE416269:APL_0835-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 21477; Mature: 21477

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLCDTDIERYLDEGIIEIIPRPSNEKITGATVDVRLGNSFRVFREHATPYIDLSGPREE
CCCCHHHHHHHHHCCCEEEECCCCCCEEECEEEEEEECCCEEEHHHCCCCEEECCCCHHH
VTAQLHKVMSEEIIIADGEAFFLHPGELALATTLESVTLPDNVVGWLDGRSSLARLGLMV
HHHHHHHHHCCCEEEECCCEEEEECCCEEEEEHHHHCCCCCHHEEECCCHHHHHHHCEEE
HVTAHRIDPGWQGKIVLEFFNAGKLPLALRPNMAIGALSFEILSGHAAKPYNARKDAKYK
EEEEEECCCCCCCEEEEEEECCCCCCEEECCCCEEEHEEEEEECCCCCCCCCCCCCCCCC
NQQSAVSSRINQDD
HHHHHHHHHCCCCC
>Mature Secondary Structure
MRLCDTDIERYLDEGIIEIIPRPSNEKITGATVDVRLGNSFRVFREHATPYIDLSGPREE
CCCCHHHHHHHHHCCCEEEECCCCCCEEECEEEEEEECCCEEEHHHCCCCEEECCCCHHH
VTAQLHKVMSEEIIIADGEAFFLHPGELALATTLESVTLPDNVVGWLDGRSSLARLGLMV
HHHHHHHHHCCCEEEECCCEEEEECCCEEEEEHHHHCCCCCHHEEECCCHHHHHHHCEEE
HVTAHRIDPGWQGKIVLEFFNAGKLPLALRPNMAIGALSFEILSGHAAKPYNARKDAKYK
EEEEEECCCCCCCEEEEEEECCCCCCEEECCCCEEEHEEEEEECCCCCCCCCCCCCCCCC
NQQSAVSSRINQDD
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA