Click here to switch to the map view.

The map label for this gene is glpR [H]

Identifier: 126208299

GI number: 126208299

Start: 951400

End: 952161

Strand: Reverse

Name: glpR [H]

Synonym: APL_0823

Alternate gene names: 126208299

Gene position: 952161-951400 (Counterclockwise)

Preceding gene: 126208300

Following gene: 126208298

Centisome position: 41.86

GC content: 41.6

Gene sequence:

>762_bases
ATGAAACAATCTATTCGTCACAATAAAATTATCGAACTGGTTAATCAGTTAGGTTATGTCAGTACGGAAGAATTAGTTGC
CCAATTAGATGTCAGTTCTCAAACGATTCGCCGTGATTTAAACGAATTAGCCGAAAAGAATTTGATTCGCCGCCATCACG
GTGGTGCGGGTATGCCGTCTAACAGCGAAAACAGCGATTATACCGAACGTAAACAGTTTTTTTCGGAACAAAAAAATGAA
ATTGCGCGCCACGTAGCGGCAATGATCCCGAACGGTGCTTCATTATTCTTAGATATTGGTACAACCTCTGAAGCTGTGGC
TTATGCACTGTTATCGCATCAAAATTTGCGTATTGTGACCAATAATCTGAATGCCGCACATATTTTAATGCAGAAGGAAG
ATTTCCATATTACGGTAGCCGGTGGTAATTTGCGTACCGACGGCGGTTTAATCGGTGAAGCAACGGTGAATTTTATCAGC
CAATTCCGCTTGGATTTCGGTATTTTGGGCATTAGTGCGATCGATAGTGACGGCTCAATGCTCGATTACGATTACCACGA
AGTGCAAGTGAAACGCGCTTTGATGCAGAGTTCCCGCCAAGTGATTTTGGTAACCGATCATTCAAAATTCAGTCGTAGCG
CAATTGTCCGCTTAGGCGATATTACCGAAGTGAATTATTTGTTTACAGATTTGCCGTTACCATTAGAATTACAGCAACGA
TTAGTTTCAACCAAAGTAGCAGTACAAATCTGCGGTAATTAA

Upstream 100 bases:

>100_bases
GGTTATGCGGTAGAACTTGTTGAAAAATTGTAAAATTTAAGTTAAAAATGACCGCTGGTAAGCGGTCATTTTTTTGAAAA
CTTTGCGGAGGAATAAGTAA

Downstream 100 bases:

>100_bases
TGACAACTTTTTTTCAACAACATTTTTCTCGGAATAAATGGCTGGCGTATGCACAATTAATGCGCTTTGATAAGCCGATT
GGAACTTTACTTTTGCTTCA

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MKQSIRHNKIIELVNQLGYVSTEELVAQLDVSSQTIRRDLNELAEKNLIRRHHGGAGMPSNSENSDYTERKQFFSEQKNE
IARHVAAMIPNGASLFLDIGTTSEAVAYALLSHQNLRIVTNNLNAAHILMQKEDFHITVAGGNLRTDGGLIGEATVNFIS
QFRLDFGILGISAIDSDGSMLDYDYHEVQVKRALMQSSRQVILVTDHSKFSRSAIVRLGDITEVNYLFTDLPLPLELQQR
LVSTKVAVQICGN

Sequences:

>Translated_253_residues
MKQSIRHNKIIELVNQLGYVSTEELVAQLDVSSQTIRRDLNELAEKNLIRRHHGGAGMPSNSENSDYTERKQFFSEQKNE
IARHVAAMIPNGASLFLDIGTTSEAVAYALLSHQNLRIVTNNLNAAHILMQKEDFHITVAGGNLRTDGGLIGEATVNFIS
QFRLDFGILGISAIDSDGSMLDYDYHEVQVKRALMQSSRQVILVTDHSKFSRSAIVRLGDITEVNYLFTDLPLPLELQQR
LVSTKVAVQICGN
>Mature_253_residues
MKQSIRHNKIIELVNQLGYVSTEELVAQLDVSSQTIRRDLNELAEKNLIRRHHGGAGMPSNSENSDYTERKQFFSEQKNE
IARHVAAMIPNGASLFLDIGTTSEAVAYALLSHQNLRIVTNNLNAAHILMQKEDFHITVAGGNLRTDGGLIGEATVNFIS
QFRLDFGILGISAIDSDGSMLDYDYHEVQVKRALMQSSRQVILVTDHSKFSRSAIVRLGDITEVNYLFTDLPLPLELQQR
LVSTKVAVQICGN

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=63.4920634920635, Blast_Score=331, Evalue=2e-92,
Organism=Escherichia coli, GI87082344, Length=244, Percent_Identity=41.8032786885246, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1788069, Length=228, Percent_Identity=29.8245614035088, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789170, Length=232, Percent_Identity=31.0344827586207, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI226510968, Length=250, Percent_Identity=28.8, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=26.8774703557312, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1789059, Length=257, Percent_Identity=29.1828793774319, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787540, Length=227, Percent_Identity=26.8722466960352, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790753, Length=239, Percent_Identity=24.2677824267782, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787063, Length=234, Percent_Identity=23.5042735042735, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28178; Mature: 28178

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQSIRHNKIIELVNQLGYVSTEELVAQLDVSSQTIRRDLNELAEKNLIRRHHGGAGMPS
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NSENSDYTERKQFFSEQKNEIARHVAAMIPNGASLFLDIGTTSEAVAYALLSHQNLRIVT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNAAHILMQKEDFHITVAGGNLRTDGGLIGEATVNFISQFRLDFGILGISAIDSDGSM
CCCCEEEEEEECCCEEEEEECCCEECCCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCCE
LDYDYHEVQVKRALMQSSRQVILVTDHSKFSRSAIVRLGDITEVNYLFTDLPLPLELQQR
ECCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHEEECCCCEEHHEEECCCCCHHHHHH
LVSTKVAVQICGN
HHHHHHEEEECCC
>Mature Secondary Structure
MKQSIRHNKIIELVNQLGYVSTEELVAQLDVSSQTIRRDLNELAEKNLIRRHHGGAGMPS
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NSENSDYTERKQFFSEQKNEIARHVAAMIPNGASLFLDIGTTSEAVAYALLSHQNLRIVT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNAAHILMQKEDFHITVAGGNLRTDGGLIGEATVNFISQFRLDFGILGISAIDSDGSM
CCCCEEEEEEECCCEEEEEECCCEECCCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCCE
LDYDYHEVQVKRALMQSSRQVILVTDHSKFSRSAIVRLGDITEVNYLFTDLPLPLELQQR
ECCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHEEECCCCEEHHEEECCCCCHHHHHH
LVSTKVAVQICGN
HHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]