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The map label for this gene is hsdM [C]

Identifier: 126176533

GI number: 126176533

Start: 5092066

End: 5093763

Strand: Reverse

Name: hsdM [C]

Synonym: Sbal_4352

Alternate gene names: 126176533

Gene position: 5093763-5092066 (Counterclockwise)

Preceding gene: 126176534

Following gene: 126176532

Centisome position: 99.34

GC content: 44.52

Gene sequence:

>1698_bases
ATGGCACAACTAGAAAATATTGAAGCAATTGAAAAACGCCTTTGGAAATCGGCTGATACCTTACGCGCCAACTCAGAGTT
GGCTAGCAATGAATACTTTCTACCGGTAATGGGGCTGATTTTTCTACGTCACGCATACAGCCGCTATTTGTCGGTAAAAG
ATGAAATCGTTACAACTCTGCCCAGCCGTGGTGGTAAAACGCGCGAATTAACTAAAGAAGACTTTTCGAAAAAGAGCGCT
ATCTTCTTAAAACCTGATGCTCAGTTTGATGCGCTTATTGCTTTAACCGATGCCGATAATCGCGCTGAAGCCATCATAAA
TGCGATGGACTCTATCGAGGCTGACTATACCAATTTGCGTAATCAGCTACCCAAGCAGGAATACAACAATATTCCTAATG
ATGTTTTGGGTATGTTGTTACGTACATTAAACCCAGAAGAATTAAAAAAAGCCACTGGCGATATTTTTGGCCGTATCTAC
GAATACTTCCTTACTCAGTTTGCTGATCAAGGTGCGCACGATGGCGGTGAATTCTTTACCCCCGTATCGCTAGTGCAGTT
ATTGGTTAATGTGATTGAGCCCGACCATGGCAAAATTTTTGATCCCGCTTGTGGCTCTGGCGGTATGTTTGTGCAAAGTG
CCCATTTTATGGCGCGTCACGCGCAAGACCCACACGAACTCACTTTCTATGGCCATGAGAAAAACCGAGTCACGACACGC
TTAGCGAAGATGAACCTTGCTGTACATGGCTTAGAAGGTAATGTTGAAGGCGGTGAGAGTGCGATTACCTACTACAACGA
CCCACATGAAGGTTTATTTGGCACAGTCGATTACGTGATGGCTAACCCGCCGTTTAACGTGGATGAAGTCGATGCAGACA
AAATCAAAGGCGATAAACATCGCTTACCGTTTGGTTTGCCCGGTGTAAACAAAAACAAAAAGGTCAGTAATGGTAACTAT
CTTTGGATCCAGTATTTTTACAGTTACCTGAATGATACCGGTCGTGCCGGTTTTGTTATGTCATCTCAAGCATCCAGTGC
CGGGCGGGATGAAGCCAAGGTGCGCGAGCAGTTAGTCAAAACCGGCGATGTTGACATTATGATCGATATTCGCAGTAACT
TTTTTTACACTCGAACTGTGCCTTGCCAGTTGTGGTTTTTAAATAAAAACAAACCAGCGCACTTAAAAGATAAAGTGCTG
ATGCTGGATGCTCGCAACGTCTACCGTAAAGTGACTCGTAAGATTTACGACTTCAGCCCCGAGCAGCAACAAAACCTGAC
AGCTGTGGTCTGGCTCTATCGTGGTGAGGGTGAACGATTTATTGAGTTGGTTCAGCAGTATATCGACAAGGCCATATTTG
AAGCATGTTATTGTGAGTTCTCAGAAGAGCTCATGTGCAATCCAGTCCCCGATTTTGTTGAGCAGCTGGATAAACTCAGC
AATGCCTTCAAACCTTTCATGGATAAGCTAGAACAAGACGGCACTTCTGTTGAACCCTATGTAGATTTTCTCAATGCCAA
GGGAACCGTTGAAGGCGGTTGGTCAAGGTTTCAGATCCTAACGAACGATCTGCAAACGTGGTGGAATCAAAACCAATATG
ACAATGGCACTAGCTTGCTGGATTTCCCCCTGTGTCAGGATAGTTGTCGCCTCAATTCATTTACAAATAAACAGGGAGCG
GTAAGTTACAGCAAGTGA

Upstream 100 bases:

>100_bases
ATTAGAACATTACATCGCATCCCAGCATAACCGCGCTAATACCATCGAAACAATCAAATCACCAAAAAGTAAATCAAGTG
ATAATTAGGAATTAGGCCCC

Downstream 100 bases:

>100_bases
ATTATCAAAGGCATTCAGGTCAATTTAAAGAAGCTATATTAAACAAGCTTAGTCAAAGTGGTTTGTCGGTTCGTCAGTTT
GCAGAGCAAGAAGGCATTAA

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MAQLENIEAIEKRLWKSADTLRANSELASNEYFLPVMGLIFLRHAYSRYLSVKDEIVTTLPSRGGKTRELTKEDFSKKSA
IFLKPDAQFDALIALTDADNRAEAIINAMDSIEADYTNLRNQLPKQEYNNIPNDVLGMLLRTLNPEELKKATGDIFGRIY
EYFLTQFADQGAHDGGEFFTPVSLVQLLVNVIEPDHGKIFDPACGSGGMFVQSAHFMARHAQDPHELTFYGHEKNRVTTR
LAKMNLAVHGLEGNVEGGESAITYYNDPHEGLFGTVDYVMANPPFNVDEVDADKIKGDKHRLPFGLPGVNKNKKVSNGNY
LWIQYFYSYLNDTGRAGFVMSSQASSAGRDEAKVREQLVKTGDVDIMIDIRSNFFYTRTVPCQLWFLNKNKPAHLKDKVL
MLDARNVYRKVTRKIYDFSPEQQQNLTAVVWLYRGEGERFIELVQQYIDKAIFEACYCEFSEELMCNPVPDFVEQLDKLS
NAFKPFMDKLEQDGTSVEPYVDFLNAKGTVEGGWSRFQILTNDLQTWWNQNQYDNGTSLLDFPLCQDSCRLNSFTNKQGA
VSYSK

Sequences:

>Translated_565_residues
MAQLENIEAIEKRLWKSADTLRANSELASNEYFLPVMGLIFLRHAYSRYLSVKDEIVTTLPSRGGKTRELTKEDFSKKSA
IFLKPDAQFDALIALTDADNRAEAIINAMDSIEADYTNLRNQLPKQEYNNIPNDVLGMLLRTLNPEELKKATGDIFGRIY
EYFLTQFADQGAHDGGEFFTPVSLVQLLVNVIEPDHGKIFDPACGSGGMFVQSAHFMARHAQDPHELTFYGHEKNRVTTR
LAKMNLAVHGLEGNVEGGESAITYYNDPHEGLFGTVDYVMANPPFNVDEVDADKIKGDKHRLPFGLPGVNKNKKVSNGNY
LWIQYFYSYLNDTGRAGFVMSSQASSAGRDEAKVREQLVKTGDVDIMIDIRSNFFYTRTVPCQLWFLNKNKPAHLKDKVL
MLDARNVYRKVTRKIYDFSPEQQQNLTAVVWLYRGEGERFIELVQQYIDKAIFEACYCEFSEELMCNPVPDFVEQLDKLS
NAFKPFMDKLEQDGTSVEPYVDFLNAKGTVEGGWSRFQILTNDLQTWWNQNQYDNGTSLLDFPLCQDSCRLNSFTNKQGA
VSYSK
>Mature_564_residues
AQLENIEAIEKRLWKSADTLRANSELASNEYFLPVMGLIFLRHAYSRYLSVKDEIVTTLPSRGGKTRELTKEDFSKKSAI
FLKPDAQFDALIALTDADNRAEAIINAMDSIEADYTNLRNQLPKQEYNNIPNDVLGMLLRTLNPEELKKATGDIFGRIYE
YFLTQFADQGAHDGGEFFTPVSLVQLLVNVIEPDHGKIFDPACGSGGMFVQSAHFMARHAQDPHELTFYGHEKNRVTTRL
AKMNLAVHGLEGNVEGGESAITYYNDPHEGLFGTVDYVMANPPFNVDEVDADKIKGDKHRLPFGLPGVNKNKKVSNGNYL
WIQYFYSYLNDTGRAGFVMSSQASSAGRDEAKVREQLVKTGDVDIMIDIRSNFFYTRTVPCQLWFLNKNKPAHLKDKVLM
LDARNVYRKVTRKIYDFSPEQQQNLTAVVWLYRGEGERFIELVQQYIDKAIFEACYCEFSEELMCNPVPDFVEQLDKLSN
AFKPFMDKLEQDGTSVEPYVDFLNAKGTVEGGWSRFQILTNDLQTWWNQNQYDNGTSLLDFPLCQDSCRLNSFTNKQGAV
SYSK

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=295, Percent_Identity=24.0677966101695, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 64311; Mature: 64180

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLENIEAIEKRLWKSADTLRANSELASNEYFLPVMGLIFLRHAYSRYLSVKDEIVTTL
CCCCHHHHHHHHHHHHCHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PSRGGKTRELTKEDFSKKSAIFLKPDAQFDALIALTDADNRAEAIINAMDSIEADYTNLR
CCCCCCCCHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
NQLPKQEYNNIPNDVLGMLLRTLNPEELKKATGDIFGRIYEYFLTQFADQGAHDGGEFFT
HHCCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PVSLVQLLVNVIEPDHGKIFDPACGSGGMFVQSAHFMARHAQDPHELTFYGHEKNRVTTR
HHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
LAKMNLAVHGLEGNVEGGESAITYYNDPHEGLFGTVDYVMANPPFNVDEVDADKIKGDKH
HHHHHEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHEEECCCCCCCCCCHHHCCCCCC
RLPFGLPGVNKNKKVSNGNYLWIQYFYSYLNDTGRAGFVMSSQASSAGRDEAKVREQLVK
CCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHH
TGDVDIMIDIRSNFFYTRTVPCQLWFLNKNKPAHLKDKVLMLDARNVYRKVTRKIYDFSP
CCCEEEEEEECCCEEEEEECCEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCC
EQQQNLTAVVWLYRGEGERFIELVQQYIDKAIFEACYCEFSEELMCNPVPDFVEQLDKLS
CHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
NAFKPFMDKLEQDGTSVEPYVDFLNAKGTVEGGWSRFQILTNDLQTWWNQNQYDNGTSLL
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEE
DFPLCQDSCRLNSFTNKQGAVSYSK
ECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AQLENIEAIEKRLWKSADTLRANSELASNEYFLPVMGLIFLRHAYSRYLSVKDEIVTTL
CCCHHHHHHHHHHHHCHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PSRGGKTRELTKEDFSKKSAIFLKPDAQFDALIALTDADNRAEAIINAMDSIEADYTNLR
CCCCCCCCHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
NQLPKQEYNNIPNDVLGMLLRTLNPEELKKATGDIFGRIYEYFLTQFADQGAHDGGEFFT
HHCCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PVSLVQLLVNVIEPDHGKIFDPACGSGGMFVQSAHFMARHAQDPHELTFYGHEKNRVTTR
HHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
LAKMNLAVHGLEGNVEGGESAITYYNDPHEGLFGTVDYVMANPPFNVDEVDADKIKGDKH
HHHHHEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHEEECCCCCCCCCCHHHCCCCCC
RLPFGLPGVNKNKKVSNGNYLWIQYFYSYLNDTGRAGFVMSSQASSAGRDEAKVREQLVK
CCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHH
TGDVDIMIDIRSNFFYTRTVPCQLWFLNKNKPAHLKDKVLMLDARNVYRKVTRKIYDFSP
CCCEEEEEEECCCEEEEEECCEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCC
EQQQNLTAVVWLYRGEGERFIELVQQYIDKAIFEACYCEFSEELMCNPVPDFVEQLDKLS
CHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
NAFKPFMDKLEQDGTSVEPYVDFLNAKGTVEGGWSRFQILTNDLQTWWNQNQYDNGTSLL
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEE
DFPLCQDSCRLNSFTNKQGAVSYSK
ECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]