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The map label for this gene is kdpE [H]

Identifier: 126176488

GI number: 126176488

Start: 5039312

End: 5040001

Strand: Direct

Name: kdpE [H]

Synonym: Sbal_4303

Alternate gene names: 126176488

Gene position: 5039312-5040001 (Clockwise)

Preceding gene: 126176487

Following gene: 126176489

Centisome position: 98.28

GC content: 50.29

Gene sequence:

>690_bases
ATGGCTTACAAGGTGCTGGTTGTCGATGACGAAGCGCAAATTCACACTTTTATGCGGATATCGTTAGAAGCGGAAGGCTT
TGAATATCATGGCGCCGCCTCGATTGCCTCTGCCCTCGCCCAATATCAAGCCCAACGGCCACACGTGTTAGTGCTCGACC
TTGGCTTACCCGACGGCGATGGCATCAGCTTGCTGCAAAACCTACGGCAGCATGACAAAGTGCCCGTGCTTATCTTAACC
GCGCGCGATCAAGAGGAAGAGAAAATCCGCCTGCTGGAAGCGGGCGCCAATGATTATCTCAGCAAGCCATTTGGGATCAG
GGAGTTAATCGCGCGCATTAAGGTATTAGTCCGCGACTTAGTAGATGAACCCGCCTTGAGTGATGTGCTGCAGTTTGGCG
CACTTAAGCTGCAAAAAAGTACCCACCAGCTTTGGCTCGACCAGCAAGAAATCGCCTTAACTAAAAAGGAGTTTGCCCTG
ATGGAGACCTTAATGTCTCACCCTGGTCAGTTAGTGAAACAAACTGAATTGCTGCGGGATATTTGGGGCGAAACCCATAC
CGATGACAGTCATTATCTGCGGATCTTGGTCAGTCAGTTACGCAAAAAGCTCAACGACAGCACAGAGCAACAGCTGATCA
AGACAGAAGCGGGACTCGGCTATCGCTTGACTGACATGAGTCAAAAATAA

Upstream 100 bases:

>100_bases
GGGCATTATTACCGCCCATGGCGGCCAGATCAGCGCCGAACCTGTGGCTAAGGGCAGCCTTATTCGTATCGCTTTGCCGA
TTAAAAAGGGAGAGCAATAA

Downstream 100 bases:

>100_bases
CGTTTTTATCATCAACAACACTTTCAAAAAAATCGTAAAAGGATGTTTGTATGGCGCATTTTACCGTTATTGGCTTAGGG
CGATTTGGCATCGCCGCCAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MAYKVLVVDDEAQIHTFMRISLEAEGFEYHGAASIASALAQYQAQRPHVLVLDLGLPDGDGISLLQNLRQHDKVPVLILT
ARDQEEEKIRLLEAGANDYLSKPFGIRELIARIKVLVRDLVDEPALSDVLQFGALKLQKSTHQLWLDQQEIALTKKEFAL
METLMSHPGQLVKQTELLRDIWGETHTDDSHYLRILVSQLRKKLNDSTEQQLIKTEAGLGYRLTDMSQK

Sequences:

>Translated_229_residues
MAYKVLVVDDEAQIHTFMRISLEAEGFEYHGAASIASALAQYQAQRPHVLVLDLGLPDGDGISLLQNLRQHDKVPVLILT
ARDQEEEKIRLLEAGANDYLSKPFGIRELIARIKVLVRDLVDEPALSDVLQFGALKLQKSTHQLWLDQQEIALTKKEFAL
METLMSHPGQLVKQTELLRDIWGETHTDDSHYLRILVSQLRKKLNDSTEQQLIKTEAGLGYRLTDMSQK
>Mature_228_residues
AYKVLVVDDEAQIHTFMRISLEAEGFEYHGAASIASALAQYQAQRPHVLVLDLGLPDGDGISLLQNLRQHDKVPVLILTA
RDQEEEKIRLLEAGANDYLSKPFGIRELIARIKVLVRDLVDEPALSDVLQFGALKLQKSTHQLWLDQQEIALTKKEFALM
ETLMSHPGQLVKQTELLRDIWGETHTDDSHYLRILVSQLRKKLNDSTEQQLIKTEAGLGYRLTDMSQK

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=39.8190045248869, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=33.0396475770925, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=32.8767123287671, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=32.1100917431193, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=32.7433628318584, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=35.1351351351351, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=34.2342342342342, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=29.8642533936652, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=31.9148936170213, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=29.1845493562232, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=30.1310043668122, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=28.1385281385281, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=30.8695652173913, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=34.5794392523364, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693140, Length=189, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25978; Mature: 25847

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYKVLVVDDEAQIHTFMRISLEAEGFEYHGAASIASALAQYQAQRPHVLVLDLGLPDGD
CCEEEEEECCCHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC
GISLLQNLRQHDKVPVLILTARDQEEEKIRLLEAGANDYLSKPFGIRELIARIKVLVRDL
CHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHH
VDEPALSDVLQFGALKLQKSTHQLWLDQQEIALTKKEFALMETLMSHPGQLVKQTELLRD
HCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IWGETHTDDSHYLRILVSQLRKKLNDSTEQQLIKTEAGLGYRLTDMSQK
HHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCC
>Mature Secondary Structure 
AYKVLVVDDEAQIHTFMRISLEAEGFEYHGAASIASALAQYQAQRPHVLVLDLGLPDGD
CEEEEEECCCHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC
GISLLQNLRQHDKVPVLILTARDQEEEKIRLLEAGANDYLSKPFGIRELIARIKVLVRDL
CHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHH
VDEPALSDVLQFGALKLQKSTHQLWLDQQEIALTKKEFALMETLMSHPGQLVKQTELLRD
HCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IWGETHTDDSHYLRILVSQLRKKLNDSTEQQLIKTEAGLGYRLTDMSQK
HHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]