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The map label for this gene is aroB [H]

Identifier: 126176297

GI number: 126176297

Start: 4819627

End: 4820703

Strand: Reverse

Name: aroB [H]

Synonym: Sbal_4112

Alternate gene names: 126176297

Gene position: 4820703-4819627 (Counterclockwise)

Preceding gene: 126176298

Following gene: 126176296

Centisome position: 94.02

GC content: 45.68

Gene sequence:

>1077_bases
ATGAAGCAAATTCAGGTTGATTTAGGTGTACGTAGTTATCCCATTTACATTGGCCAGAATTTGATGAGTGATGGCGAGAC
CTTGTCTCGCTACCTGCTTAAAAAACGTATTCTTATCGTCACCAATGAAACTGTCGCGCCTTTGTATCTTAAACAGATAC
AAGAGACGATGGCTTCGTTTGGTGAGGTAGAGAGTGTTATCCTCCCCGATGGCGAACAATTCAAAGACTTAGCGCATCTA
GATACTATTTTTACTGCATTGCTGCAGCAAAACTATGGTCGAGATTCTGTGCTGGTGGCTTTGGGTGGCGGCGTAATTGG
TGATATGACGGGCTTTGCCGCGGCATGTTATCAACGTGGGATCGATTTTATTCAAATTCCGACAACCCTATTGTCGCAGG
TGGATTCTTCCGTCGGCGGTAAAACGGCTGTTAACCATCCTCTTGGTAAAAACATGATTGGGGCCTTTTATCAGCCACAA
ATCGTGCTTATCGATACTTTATGTTTACATACGCTTCCAGCGCGCGAGTTTGCGGCGGGAATGGCGGAAGTCATCAAGTA
TGGCATCATGTGGGATGCTGATTTTTTTCAATGGCTTGAAGATAATGTAACGGCACTAAAAACCTTAGATGCCCAAGCAT
TGGTTTATGCTATCTCCCGTTGCTGTGAGATTAAGGCCGATGTAGTTAGCCAAGACGAAACTGAGCAGGGTGTACGTGCT
TTATTGAATCTGGGTCATACCTTTGGTCATGCGATTGAAGCCGAAATGGGCTACGGTAATTGGTTGCATGGTGAAGCCGT
GTCAGCTGGCACAGTCCTTGCTGCTCAAACAGCTAAAGCACTGGGGCTTATCGATGAGTCAATAGTTTGTCGTATCATAC
AGTTACTACAAGCTTTTGATCTTCCAGTGAGAGCGCCGGAATCTATGGATTTCGACAGTTTCATTCAACATATGCGACGC
GATAAAAAAGTTTTAGGCGGTCAGATTCGACTGGTGCTCCCAACGGCTATAGGCCGCGCGGATGTGTTTAGTCAAGTCAC
TGAATCTACCCTCGAACAGGTTATTCGCTGCGCATAA

Upstream 100 bases:

>100_bases
GTACGAAGAAATTGCCGATGTGATTGTCAAAACCGATGATCAAAGCGCAAAGATTGTCGCCAATCAGATCATTGAGCAAT
TAGGTTTTTAGGCAGAATTT

Downstream 100 bases:

>100_bases
ACACTGTGTGGTGGGCGAGTGACGTTTCAAGGTTCTGTCTTGCTTCCTTCTCAGGAAGCCCTCATACAAAGAATGCATCA
TGTTGCCAGTTATAGCGATC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKQIQVDLGVRSYPIYIGQNLMSDGETLSRYLLKKRILIVTNETVAPLYLKQIQETMASFGEVESVILPDGEQFKDLAHL
DTIFTALLQQNYGRDSVLVALGGGVIGDMTGFAAACYQRGIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQ
IVLIDTLCLHTLPAREFAAGMAEVIKYGIMWDADFFQWLEDNVTALKTLDAQALVYAISRCCEIKADVVSQDETEQGVRA
LLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVLAAQTAKALGLIDESIVCRIIQLLQAFDLPVRAPESMDFDSFIQHMRR
DKKVLGGQIRLVLPTAIGRADVFSQVTESTLEQVIRCA

Sequences:

>Translated_358_residues
MKQIQVDLGVRSYPIYIGQNLMSDGETLSRYLLKKRILIVTNETVAPLYLKQIQETMASFGEVESVILPDGEQFKDLAHL
DTIFTALLQQNYGRDSVLVALGGGVIGDMTGFAAACYQRGIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQ
IVLIDTLCLHTLPAREFAAGMAEVIKYGIMWDADFFQWLEDNVTALKTLDAQALVYAISRCCEIKADVVSQDETEQGVRA
LLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVLAAQTAKALGLIDESIVCRIIQLLQAFDLPVRAPESMDFDSFIQHMRR
DKKVLGGQIRLVLPTAIGRADVFSQVTESTLEQVIRCA
>Mature_358_residues
MKQIQVDLGVRSYPIYIGQNLMSDGETLSRYLLKKRILIVTNETVAPLYLKQIQETMASFGEVESVILPDGEQFKDLAHL
DTIFTALLQQNYGRDSVLVALGGGVIGDMTGFAAACYQRGIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQ
IVLIDTLCLHTLPAREFAAGMAEVIKYGIMWDADFFQWLEDNVTALKTLDAQALVYAISRCCEIKADVVSQDETEQGVRA
LLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVLAAQTAKALGLIDESIVCRIIQLLQAFDLPVRAPESMDFDSFIQHMRR
DKKVLGGQIRLVLPTAIGRADVFSQVTESTLEQVIRCA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=359, Percent_Identity=60.7242339832869, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6320332, Length=368, Percent_Identity=36.1413043478261, Blast_Score=210, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39259; Mature: 39259

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIQVDLGVRSYPIYIGQNLMSDGETLSRYLLKKRILIVTNETVAPLYLKQIQETMASF
CCEEEEECCCCCCCCEECHHHHCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHH
GEVESVILPDGEQFKDLAHLDTIFTALLQQNYGRDSVLVALGGGVIGDMTGFAAACYQRG
HCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
IDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQIVLIDTLCLHTLPAREFAAG
CCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
MAEVIKYGIMWDADFFQWLEDNVTALKTLDAQALVYAISRCCEIKADVVSQDETEQGVRA
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVLAAQTAKALGLIDESIVCRIIQLLQAFD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPVRAPESMDFDSFIQHMRRDKKVLGGQIRLVLPTAIGRADVFSQVTESTLEQVIRCA
CCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQIQVDLGVRSYPIYIGQNLMSDGETLSRYLLKKRILIVTNETVAPLYLKQIQETMASF
CCEEEEECCCCCCCCEECHHHHCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHH
GEVESVILPDGEQFKDLAHLDTIFTALLQQNYGRDSVLVALGGGVIGDMTGFAAACYQRG
HCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
IDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQIVLIDTLCLHTLPAREFAAG
CCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
MAEVIKYGIMWDADFFQWLEDNVTALKTLDAQALVYAISRCCEIKADVVSQDETEQGVRA
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVLAAQTAKALGLIDESIVCRIIQLLQAFD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPVRAPESMDFDSFIQHMRRDKKVLGGQIRLVLPTAIGRADVFSQVTESTLEQVIRCA
CCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]