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The map label for this gene is ubiE [H]

Identifier: 126176085

GI number: 126176085

Start: 4573047

End: 4573802

Strand: Direct

Name: ubiE [H]

Synonym: Sbal_3895

Alternate gene names: 126176085

Gene position: 4573047-4573802 (Clockwise)

Preceding gene: 126176084

Following gene: 126176086

Centisome position: 89.19

GC content: 46.96

Gene sequence:

>756_bases
ATGTCTGAGGGCGAATCTAAAAGTACCCACTTTGGTTACAAAACCGTAGAGGCCGATAAAAAGGCCGAACTCGTTGCCGG
CGTGTTTCATTCTGTTGCCGCTAAGTACGACATAATGAACGATGTGATGTCCTTCGGCATTCACCGTTTTTGGAAGCGTT
ACACCATTGAAGTATCTGGCGCACGCCCTGGCATGAAAGTGCTCGATTTGGCTGGTGGCACAGGTGACTTAACCGCAAAA
TTCTCTCACTTAGTGGGCGATAAAGGTGAAGTGGTTTTAGCTGACATTAACGATTCCATGTTGAAAGTCGGTCGCACTAA
GTTGCGCGACAAGGGCATAGTCAACAATGTCAGTTATGTGCAAGCCAACGCCGAAGCACTGCCGTTTCCCGATAACCACT
TCGACATCATTACCATCGCCTTTGGTCTGCGTAACGTGACCGATAAAGATGCGGCGCTGCGTTCGATGAACCGCGTGCTT
AAGCCTGGTGGCAAGTTATTAGTGCTTGAGTTTTCTAAGCCTCAGCATGAAATCATGCGCAAAGTGTATGATTTATATAG
CTTCAAAGTCTTACCTAAGATGGGCGAACTCATCACTAAAGATGCCGACAGCTACGAGTATCTGGCCGAATCGATTCGTA
TGCATCCAGATCAAGACACATTAAAACAAATGATGGTGGATGCAGGCTTCGAACAAGTCGACTACACCAACATGACCGAC
GGCATTGTCGCATTGCACCGTGGTTATAAATTCTAA

Upstream 100 bases:

>100_bases
TTACTAGCTCGATCACAGAGTGATAGATCAAAGATTCAGCAAATGCAGGCGATGGCTTACACTCGCAACTAATACATTGC
AAAACAATAGGAACACATTG

Downstream 100 bases:

>100_bases
TGATGCCGCAAGAAGTTGTGCTGCTTGTCTGCGCCGCAATTGAAACGGGCCTGAAAAAACTTCAGGCTCAAGCGGGTGAC
GACTATTCACGCCAGCGCCA

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSEGESKSTHFGYKTVEADKKAELVAGVFHSVAAKYDIMNDVMSFGIHRFWKRYTIEVSGARPGMKVLDLAGGTGDLTAK
FSHLVGDKGEVVLADINDSMLKVGRTKLRDKGIVNNVSYVQANAEALPFPDNHFDIITIAFGLRNVTDKDAALRSMNRVL
KPGGKLLVLEFSKPQHEIMRKVYDLYSFKVLPKMGELITKDADSYEYLAESIRMHPDQDTLKQMMVDAGFEQVDYTNMTD
GIVALHRGYKF

Sequences:

>Translated_251_residues
MSEGESKSTHFGYKTVEADKKAELVAGVFHSVAAKYDIMNDVMSFGIHRFWKRYTIEVSGARPGMKVLDLAGGTGDLTAK
FSHLVGDKGEVVLADINDSMLKVGRTKLRDKGIVNNVSYVQANAEALPFPDNHFDIITIAFGLRNVTDKDAALRSMNRVL
KPGGKLLVLEFSKPQHEIMRKVYDLYSFKVLPKMGELITKDADSYEYLAESIRMHPDQDTLKQMMVDAGFEQVDYTNMTD
GIVALHRGYKF
>Mature_250_residues
SEGESKSTHFGYKTVEADKKAELVAGVFHSVAAKYDIMNDVMSFGIHRFWKRYTIEVSGARPGMKVLDLAGGTGDLTAKF
SHLVGDKGEVVLADINDSMLKVGRTKLRDKGIVNNVSYVQANAEALPFPDNHFDIITIAFGLRNVTDKDAALRSMNRVLK
PGGKLLVLEFSKPQHEIMRKVYDLYSFKVLPKMGELITKDADSYEYLAESIRMHPDQDTLKQMMVDAGFEQVDYTNMTDG
IVALHRGYKF

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI116063536, Length=283, Percent_Identity=43.8162544169611, Blast_Score=241, Evalue=4e-64,
Organism=Escherichia coli, GI48994983, Length=251, Percent_Identity=72.9083665338645, Blast_Score=388, Evalue=1e-109,
Organism=Escherichia coli, GI1786404, Length=88, Percent_Identity=38.6363636363636, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17557039, Length=247, Percent_Identity=41.7004048582996, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6323526, Length=267, Percent_Identity=43.0711610486891, Blast_Score=188, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24641702, Length=261, Percent_Identity=44.4444444444444, Blast_Score=240, Evalue=6e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 28094; Mature: 27962

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS01183 UBIE_1 ; PS01184 UBIE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGESKSTHFGYKTVEADKKAELVAGVFHSVAAKYDIMNDVMSFGIHRFWKRYTIEVSG
CCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
ARPGMKVLDLAGGTGDLTAKFSHLVGDKGEVVLADINDSMLKVGRTKLRDKGIVNNVSYV
CCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCEE
QANAEALPFPDNHFDIITIAFGLRNVTDKDAALRSMNRVLKPGGKLLVLEFSKPQHEIMR
EECCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
KVYDLYSFKVLPKMGELITKDADSYEYLAESIRMHPDQDTLKQMMVDAGFEQVDYTNMTD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCH
GIVALHRGYKF
HHHHHHCCCCC
>Mature Secondary Structure 
SEGESKSTHFGYKTVEADKKAELVAGVFHSVAAKYDIMNDVMSFGIHRFWKRYTIEVSG
CCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
ARPGMKVLDLAGGTGDLTAKFSHLVGDKGEVVLADINDSMLKVGRTKLRDKGIVNNVSYV
CCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCEE
QANAEALPFPDNHFDIITIAFGLRNVTDKDAALRSMNRVLKPGGKLLVLEFSKPQHEIMR
EECCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
KVYDLYSFKVLPKMGELITKDADSYEYLAESIRMHPDQDTLKQMMVDAGFEQVDYTNMTD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCH
GIVALHRGYKF
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA