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The map label for this gene is pnuC [H]

Identifier: 126175986

GI number: 126175986

Start: 4454695

End: 4455429

Strand: Reverse

Name: pnuC [H]

Synonym: Sbal_3795

Alternate gene names: 126175986

Gene position: 4455429-4454695 (Counterclockwise)

Preceding gene: 126175987

Following gene: 126175985

Centisome position: 86.89

GC content: 40.41

Gene sequence:

>735_bases
ATGGACATTATTTCATGGTTTAGTATCAATAATACCTTTGTTAATATTCCTCTGGGCAGTGGCTATGCCATGTCATGGAT
TGAAATGGTTGGCACTGTATTTGGTTTATTGTGTATTTGGTGTGCAAGCAAAGAGAAAACGATTAACTATTTTTTTGGTT
TAATTAATGTGACTTTGTTTGCAATCATCTTTTACCAAATCCAACTATATGGATTATTAATTCTGCAATTATTCTTTTTT
GTCGCCAATATCTACGGTTGGTATGCGTGGACTCGTCCCAATACTATTGATGGCGAATCACTACAAGTGCGTTGGCTATC
TAAACAAAAACTGCTCATTACTGGCGTAGTGAGTATTGTCGCTATTTGTTTGATGACTATCTTCATTGACCCTTTCTTTG
CAGCGTTAGCTAAAATCGCCACTAACACACTCAACGCCTTCGGCAATGATATCGTCCTTAAACCTTTAGATCCTGATGCC
TTCCCGTTTTGGGATGCCACAATGACTGTATTGTCAGTGGTCGCGCAAATTCTCATGACCCGCAAGTATGTTGAAAACTG
GATTCTGTGGGTTGTGATAAACGTGATTAGTGTTGGTGTGTATGCTGCGCAAGGTGTTTACGCCATGTCTATCGAATACG
CAATTCTGCTATTCATCGCATTGAATGGCACGCGAGTATGGATGGCAACTGCAAAGTCTAACCAAGCCAAATCCTCAAAG
CAGGCGGTGCTATGA

Upstream 100 bases:

>100_bases
TCAAACCATCGCCAATGAAAGGGACAAAAGTCCGTTTCTTAGCCTTGATTATTGAGTATTTTTATTATCTCGATGTTTAA
CGGATAAAAAGGATCGCTAT

Downstream 100 bases:

>100_bases
ACCTACAACCACACATTGCCGTCAGTGCTGACGATATAGCTTCTAGAGTGATTGTGTGTGGTGATCCTGCTCGTGCAGCG
CGTATCGCGGGTTGGTGTGA

Product: nicotinamide mononucleotide transporter PnuC

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MDIISWFSINNTFVNIPLGSGYAMSWIEMVGTVFGLLCIWCASKEKTINYFFGLINVTLFAIIFYQIQLYGLLILQLFFF
VANIYGWYAWTRPNTIDGESLQVRWLSKQKLLITGVVSIVAICLMTIFIDPFFAALAKIATNTLNAFGNDIVLKPLDPDA
FPFWDATMTVLSVVAQILMTRKYVENWILWVVINVISVGVYAAQGVYAMSIEYAILLFIALNGTRVWMATAKSNQAKSSK
QAVL

Sequences:

>Translated_244_residues
MDIISWFSINNTFVNIPLGSGYAMSWIEMVGTVFGLLCIWCASKEKTINYFFGLINVTLFAIIFYQIQLYGLLILQLFFF
VANIYGWYAWTRPNTIDGESLQVRWLSKQKLLITGVVSIVAICLMTIFIDPFFAALAKIATNTLNAFGNDIVLKPLDPDA
FPFWDATMTVLSVVAQILMTRKYVENWILWVVINVISVGVYAAQGVYAMSIEYAILLFIALNGTRVWMATAKSNQAKSSK
QAVL
>Mature_244_residues
MDIISWFSINNTFVNIPLGSGYAMSWIEMVGTVFGLLCIWCASKEKTINYFFGLINVTLFAIIFYQIQLYGLLILQLFFF
VANIYGWYAWTRPNTIDGESLQVRWLSKQKLLITGVVSIVAICLMTIFIDPFFAALAKIATNTLNAFGNDIVLKPLDPDA
FPFWDATMTVLSVVAQILMTRKYVENWILWVVINVISVGVYAAQGVYAMSIEYAILLFIALNGTRVWMATAKSNQAKSSK
QAVL

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=236, Percent_Identity=58.8983050847458, Blast_Score=268, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 27468; Mature: 27468

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIISWFSINNTFVNIPLGSGYAMSWIEMVGTVFGLLCIWCASKEKTINYFFGLINVTLF
CCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AIIFYQIQLYGLLILQLFFFVANIYGWYAWTRPNTIDGESLQVRWLSKQKLLITGVVSIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHH
AICLMTIFIDPFFAALAKIATNTLNAFGNDIVLKPLDPDAFPFWDATMTVLSVVAQILMT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
RKYVENWILWVVINVISVGVYAAQGVYAMSIEYAILLFIALNGTRVWMATAKSNQAKSSK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCC
QAVL
CCCC
>Mature Secondary Structure
MDIISWFSINNTFVNIPLGSGYAMSWIEMVGTVFGLLCIWCASKEKTINYFFGLINVTLF
CCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AIIFYQIQLYGLLILQLFFFVANIYGWYAWTRPNTIDGESLQVRWLSKQKLLITGVVSIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHH
AICLMTIFIDPFFAALAKIATNTLNAFGNDIVLKPLDPDAFPFWDATMTVLSVVAQILMT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
RKYVENWILWVVINVISVGVYAAQGVYAMSIEYAILLFIALNGTRVWMATAKSNQAKSSK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCC
QAVL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 2841129; 2198247 [H]