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The map label for this gene is purC [H]

Identifier: 126175977

GI number: 126175977

Start: 4442693

End: 4443796

Strand: Direct

Name: purC [H]

Synonym: Sbal_3785

Alternate gene names: 126175977

Gene position: 4442693-4443796 (Clockwise)

Preceding gene: 126175976

Following gene: 126175978

Centisome position: 86.65

GC content: 49.64

Gene sequence:

>1104_bases
ATGAGTCTTGCTGATTCCGTACTTGCCATCAATAACGATTTGCCTATCCGCACCGACAGCCCAGTCCACAGCGGCAAGGT
TCGCAGCGTTTACTGGCTAACCGACGCCGACAGTCGCCGTTTAATTACCACTAAAGGTTATAACGTCCCCGAAGATACCC
CGCTCGCCATCATGGTGATCAGCGACCGTATCTCGGCCTTCGACTGTATCTTCCACGGTGAAGGCGGCCTCAAAGGCATT
CCCGGTAAAGGCGCGGCATTAAACGCGATATCTAACCATTGGTTTAAACTGTTCGCCGAAAACGGCCTAGCCGACAGCCA
TATTTTGGATATCCCGCACCCGTTCGTATGGATAGTCCAAAAAGCTCGCCCTATTAAAGTCGAAGCCATTTGTCGCCAGT
ACATCACAGGCTCAATGTGGCGCGCTTACTCAAAAGGCGAGCGAGTATTCTGTGGCATTACACTGCCAGAAGGCTTAGAG
AAAGCTCAAAAGCTCCCTGAGCTGTTAATCACTCCATCGACTAAGGGTATTTTAACCGGCATCCCAGGCGTGCCCGCCCA
AGATGACGTGAACATCAGCCGCAGCGACATCGAAGCCAACTACCAAGCCTTTGGTTTTGAAAAGCTTTCAGATATTGACC
TGTACGAGAAGCTGTTAAAAGATGGCTTTAAAGTGATTTCAAAAGCACTGGCCGACATTGACCAAGTGTTTGTCGACACT
AAGTTTGAGTTCGGTTATGTGACTGACAAAGATGGCAACTCAAAACTGATTTACATGGATGAAGTCGGTACTCCAGACTC
ATCACGTATTTGGGACGGCGCCGCCTACCGCGATGGCAAGATTTTAGAAAACTCTAAAGAGGGTTTCCGCCAGTTCCTGC
TGAATCATTTCCCCGATCCTGATGTGCTGCTTAACAAAGACAGAATGCCAGAGCGTGAAGCCCTAGCCCGCGATAATGAC
CTGCCACTTGAGGCCATGATGCAAGTGTCACGCACCTACACCGGCGTTGCCGAGAAGGTGACTGGCGCTCCAATCCCGCT
GCCAGCGAATCCAAAGGCAGATATTATTAAGATACTCAAAGATGAGTATGATCTGATTGTGTAA

Upstream 100 bases:

>100_bases
GTTGCAATGAATCTGGCTGTTGCTAACGCCATAGTCCATCTGCAAACCGACACTTATAAAAACCTTATCCCTACACTCTC
TATCCTAAGGAATACTCGTC

Downstream 100 bases:

>100_bases
TAGAGAGTTGTAATCAGATCTGAGGTTTTGAGTAGTTTACCCATAGCTGAATAGTAGAAAAGGCGCTTAGGCGCCTTTTT
GTTTACTTCGAAACTGTGTT

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSLADSVLAINNDLPIRTDSPVHSGKVRSVYWLTDADSRRLITTKGYNVPEDTPLAIMVISDRISAFDCIFHGEGGLKGI
PGKGAALNAISNHWFKLFAENGLADSHILDIPHPFVWIVQKARPIKVEAICRQYITGSMWRAYSKGERVFCGITLPEGLE
KAQKLPELLITPSTKGILTGIPGVPAQDDVNISRSDIEANYQAFGFEKLSDIDLYEKLLKDGFKVISKALADIDQVFVDT
KFEFGYVTDKDGNSKLIYMDEVGTPDSSRIWDGAAYRDGKILENSKEGFRQFLLNHFPDPDVLLNKDRMPEREALARDND
LPLEAMMQVSRTYTGVAEKVTGAPIPLPANPKADIIKILKDEYDLIV

Sequences:

>Translated_367_residues
MSLADSVLAINNDLPIRTDSPVHSGKVRSVYWLTDADSRRLITTKGYNVPEDTPLAIMVISDRISAFDCIFHGEGGLKGI
PGKGAALNAISNHWFKLFAENGLADSHILDIPHPFVWIVQKARPIKVEAICRQYITGSMWRAYSKGERVFCGITLPEGLE
KAQKLPELLITPSTKGILTGIPGVPAQDDVNISRSDIEANYQAFGFEKLSDIDLYEKLLKDGFKVISKALADIDQVFVDT
KFEFGYVTDKDGNSKLIYMDEVGTPDSSRIWDGAAYRDGKILENSKEGFRQFLLNHFPDPDVLLNKDRMPEREALARDND
LPLEAMMQVSRTYTGVAEKVTGAPIPLPANPKADIIKILKDEYDLIV
>Mature_366_residues
SLADSVLAINNDLPIRTDSPVHSGKVRSVYWLTDADSRRLITTKGYNVPEDTPLAIMVISDRISAFDCIFHGEGGLKGIP
GKGAALNAISNHWFKLFAENGLADSHILDIPHPFVWIVQKARPIKVEAICRQYITGSMWRAYSKGERVFCGITLPEGLEK
AQKLPELLITPSTKGILTGIPGVPAQDDVNISRSDIEANYQAFGFEKLSDIDLYEKLLKDGFKVISKALADIDQVFVDTK
FEFGYVTDKDGNSKLIYMDEVGTPDSSRIWDGAAYRDGKILENSKEGFRQFLLNHFPDPDVLLNKDRMPEREALARDNDL
PLEAMMQVSRTYTGVAEKVTGAPIPLPANPKADIIKILKDEYDLIV

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=298, Percent_Identity=31.8791946308725, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR014106
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 40786; Mature: 40655

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01057 SAICAR_SYNTHETASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLADSVLAINNDLPIRTDSPVHSGKVRSVYWLTDADSRRLITTKGYNVPEDTPLAIMVI
CCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEE
SDRISAFDCIFHGEGGLKGIPGKGAALNAISNHWFKLFAENGLADSHILDIPHPFVWIVQ
CCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEE
KARPIKVEAICRQYITGSMWRAYSKGERVFCGITLPEGLEKAQKLPELLITPSTKGILTG
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCCEEECCCCCCEEEC
IPGVPAQDDVNISRSDIEANYQAFGFEKLSDIDLYEKLLKDGFKVISKALADIDQVFVDT
CCCCCCCCCCCCCHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KFEFGYVTDKDGNSKLIYMDEVGTPDSSRIWDGAAYRDGKILENSKEGFRQFLLNHFPDP
CEEECEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
DVLLNKDRMPEREALARDNDLPLEAMMQVSRTYTGVAEKVTGAPIPLPANPKADIIKILK
CEEECCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
DEYDLIV
HHCCCCC
>Mature Secondary Structure 
SLADSVLAINNDLPIRTDSPVHSGKVRSVYWLTDADSRRLITTKGYNVPEDTPLAIMVI
CCCCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEE
SDRISAFDCIFHGEGGLKGIPGKGAALNAISNHWFKLFAENGLADSHILDIPHPFVWIVQ
CCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEE
KARPIKVEAICRQYITGSMWRAYSKGERVFCGITLPEGLEKAQKLPELLITPSTKGILTG
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCCEEECCCCCCEEEC
IPGVPAQDDVNISRSDIEANYQAFGFEKLSDIDLYEKLLKDGFKVISKALADIDQVFVDT
CCCCCCCCCCCCCHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KFEFGYVTDKDGNSKLIYMDEVGTPDSSRIWDGAAYRDGKILENSKEGFRQFLLNHFPDP
CEEECEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
DVLLNKDRMPEREALARDNDLPLEAMMQVSRTYTGVAEKVTGAPIPLPANPKADIIKILK
CEEECCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
DEYDLIV
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA