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The map label for this gene is mlaC [H]

Identifier: 126175854

GI number: 126175854

Start: 4280974

End: 4281636

Strand: Reverse

Name: mlaC [H]

Synonym: Sbal_3659

Alternate gene names: 126175854

Gene position: 4281636-4280974 (Counterclockwise)

Preceding gene: 126175855

Following gene: 126175853

Centisome position: 83.51

GC content: 43.29

Gene sequence:

>663_bases
ATGTTTAAAAACTTATCTCGTTTTTTACTGCCGTTAGTGATGGTTTTAGGGACAACGAGCGCTGTTGCCGCCGATGTGGT
GGTCGACACTAATGATCCGTATGCCATGGTGAAAGCCGTTGCCAATAAAACCTTTGATCGTTTTCATAAAGATAAAGCGT
TAATCGATGCTGACTCAGATCATTTAAAGGTGATCGTTCGTGAAGAACTAATGCCTTATGTCGATTATAAATACGCATCT
TACAAAGTCTTAGGCCAATATCTTAAGGATTCAACCGAAGATCAGCGTAATCGTTTCGTCGATGCCTTTGAAGGTTATTT
AGTGTCGACTTATGCCCAAGCTTTTACTGAATACACCAATCAAAAAGTGGAATTTTCACCTGGGGTTGATTTCAGCAAAG
AGAAAATGGTGGATGTGAACGTGCAGATCATCGAAGCCGGCCGTCCGCCAATCAAACTGCTGTTTAAGGCACGCCGTTTG
AAAGATGACTCATGGAAGGCATTCGACTTAGTCGCCGAAGGTGTGAGCTTACTGTCTTCTAAGCAGTCTGAAATCTCGAA
TCTGATTCGCCAGCAGGGTATCGATCCTGTGATTAAGATGCTCGAAGATCGCACCAAAGAAAAAGTGACCATCAAGGCTA
AATCAGGGAAGTCGCAGTCGTGA

Upstream 100 bases:

>100_bases
GCGACAAGATTGATGACACGCGCTCGGCATTAGTGTTGGAGGAACTGATTGGTCAGTTCTTATATAGTATGGGTTCGAAG
GATAAATAGGGGTTACCGCT

Downstream 100 bases:

>100_bases
TTGAATTTGTGCAACAAGGCACAGTTTGTCATCTCAAAGGGCGCATAACCCAAGCCGATGTCATTACACTTTGGCCACAG
CGGCAACAACTGCTGGGCGA

Product: toluene tolerance family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MFKNLSRFLLPLVMVLGTTSAVAADVVVDTNDPYAMVKAVANKTFDRFHKDKALIDADSDHLKVIVREELMPYVDYKYAS
YKVLGQYLKDSTEDQRNRFVDAFEGYLVSTYAQAFTEYTNQKVEFSPGVDFSKEKMVDVNVQIIEAGRPPIKLLFKARRL
KDDSWKAFDLVAEGVSLLSSKQSEISNLIRQQGIDPVIKMLEDRTKEKVTIKAKSGKSQS

Sequences:

>Translated_220_residues
MFKNLSRFLLPLVMVLGTTSAVAADVVVDTNDPYAMVKAVANKTFDRFHKDKALIDADSDHLKVIVREELMPYVDYKYAS
YKVLGQYLKDSTEDQRNRFVDAFEGYLVSTYAQAFTEYTNQKVEFSPGVDFSKEKMVDVNVQIIEAGRPPIKLLFKARRL
KDDSWKAFDLVAEGVSLLSSKQSEISNLIRQQGIDPVIKMLEDRTKEKVTIKAKSGKSQS
>Mature_220_residues
MFKNLSRFLLPLVMVLGTTSAVAADVVVDTNDPYAMVKAVANKTFDRFHKDKALIDADSDHLKVIVREELMPYVDYKYAS
YKVLGQYLKDSTEDQRNRFVDAFEGYLVSTYAQAFTEYTNQKVEFSPGVDFSKEKMVDVNVQIIEAGRPPIKLLFKARRL
KDDSWKAFDLVAEGVSLLSSKQSEISNLIRQQGIDPVIKMLEDRTKEKVTIKAKSGKSQS

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=216, Percent_Identity=37.5, Blast_Score=155, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 24949; Mature: 24949

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNLSRFLLPLVMVLGTTSAVAADVVVDTNDPYAMVKAVANKTFDRFHKDKALIDADSD
CCCCHHHHHHHHHHHHCCCHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEECCCCH
HLKVIVREELMPYVDYKYASYKVLGQYLKDSTEDQRNRFVDAFEGYLVSTYAQAFTEYTN
HHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QKVEFSPGVDFSKEKMVDVNVQIIEAGRPPIKLLFKARRLKDDSWKAFDLVAEGVSLLSS
CEEEECCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
KQSEISNLIRQQGIDPVIKMLEDRTKEKVTIKAKSGKSQS
HHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MFKNLSRFLLPLVMVLGTTSAVAADVVVDTNDPYAMVKAVANKTFDRFHKDKALIDADSD
CCCCHHHHHHHHHHHHCCCHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEECCCCH
HLKVIVREELMPYVDYKYASYKVLGQYLKDSTEDQRNRFVDAFEGYLVSTYAQAFTEYTN
HHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QKVEFSPGVDFSKEKMVDVNVQIIEAGRPPIKLLFKARRLKDDSWKAFDLVAEGVSLLSS
CEEEECCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
KQSEISNLIRQQGIDPVIKMLEDRTKEKVTIKAKSGKSQS
HHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]