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The map label for this gene is murA

Identifier: 126175851

GI number: 126175851

Start: 4279147

End: 4280406

Strand: Reverse

Name: murA

Synonym: Sbal_3656

Alternate gene names: 126175851

Gene position: 4280406-4279147 (Counterclockwise)

Preceding gene: 126175852

Following gene: 126175848

Centisome position: 83.48

GC content: 50.87

Gene sequence:

>1260_bases
GTGGATAAACTAACAATTCAGGCAAGCCCCCCGCTTGCCGGTGATGTGATCATTTCAGGTGCTAAAAATGCGGCTCTGCC
TATTCTGATGGCAGGCGTATTGGCCGAAACCGATTTTGTGGTTTCTAACGTGCCGAATCTTCGCGATGTGACGACTAGCT
GTAAATTATTACGCTGCCTCGGTGCTGAAGTGACTGAGCTTGGCGACGGACAGATCCGCATTTCAACCACTAATCTGAAT
GAGTTTTGTGCTCCCTACGATCTCGTGAAAACCATGCGCGCGTCTATCTTAATCTTAGGGCCGTTATTGGCGCGTTATGG
TACCGCAGACGTGTCATTGCCAGGCGGCTGTGCCATTGGCGCAAGACCGGTTAACTTACACTTACATGGCCTCGAAATGA
TGGGTGCCAAGATTGAAGTGAAAGAAGGCTATATTAAAGCCCGTGTTGATGGTCGTCTTAAGGGCGCACACATTTTCATG
GACATGGTCAGTGTCGGTGCAACCGAAAACTTGCTGATGGCTGCGGCGTTAGCCGATGGCGAAACCGTGATTGAAAACGC
GGCGCGCGAACCTGAAGTGATCGATTTGGCCAATTGCTTGATTGCCATGGGCGCAAAAATCACCGGCGTAGGCAGTGCAA
CCTTGCGTATTCAAGGGGTTGAGCGTTTACAGGGCTGTAATTACCGCGTGATGCCAGATCGTATCGAAACCGGTTCCTTC
CTGGTTGCTGCCGCGGTAACTCGTGGGCGTATTCGTTGCCTAAAAGCCGATCCTGCTTCACTTGAGTCAGTTATCGCTAA
GCTTGAAGATGCGGGCGCTAAGATTACGACGGGCGAAGATTGGATTGAGCTCGATATGCAAGGTAAGCGTCCAAAGGCGG
TCAATATCAAGACGGCACCTTATCCCGGTTTTCCAACGGATATGCAGGCGCAGTTTTGTGTGCTCAACGCTTTAGCGCAA
GGTACGGCAACCATTACCGAGACCATCTTCGAAAACCGCTTTATGCACGTGCCAGAGCTTATTCGTATGGGCGCAACCAT
GGAGCTTGAAGGTAATACCTGCATCATCCAAGGGATTGAATCCTTAAGTGGTGCGCAGGTGATGGCGACGGATTTACGCG
CGTCAGCGAGTCTAGTGATTGCGGGCTTAGTGGCCGATGGCAAGACGATTGTCGATCGTATCTATCACTTAGACCGTGGT
TACGAGCATATTGAGAATAAGTTCCAAGGTTTAGGCGCGCAGGTTGTGCGTACTCAGTAA

Upstream 100 bases:

>100_bases
CATTGCCAGCGGTGAATTACATGCATTAACGATCAAAACTTTCACGCCGACTCAATGGAAACGCGAAAAAGTTTTCAACA
TGCCTAGCTAGTGAGGAAAA

Downstream 100 bases:

>100_bases
CGAGTTATTGAGCTATTGAGTTAGGCCTGAGAGATTAAAATCTCGACCCATTAAAAAACCAGCTTAAAAGCTGGTTTTTT
GTTGTCTGCGTTTTAGTGTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MDKLTIQASPPLAGDVIISGAKNAALPILMAGVLAETDFVVSNVPNLRDVTTSCKLLRCLGAEVTELGDGQIRISTTNLN
EFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFM
DMVSVGATENLLMAAALADGETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCNYRVMPDRIETGSF
LVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMQGKRPKAVNIKTAPYPGFPTDMQAQFCVLNALAQ
GTATITETIFENRFMHVPELIRMGATMELEGNTCIIQGIESLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRG
YEHIENKFQGLGAQVVRTQ

Sequences:

>Translated_419_residues
MDKLTIQASPPLAGDVIISGAKNAALPILMAGVLAETDFVVSNVPNLRDVTTSCKLLRCLGAEVTELGDGQIRISTTNLN
EFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFM
DMVSVGATENLLMAAALADGETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCNYRVMPDRIETGSF
LVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMQGKRPKAVNIKTAPYPGFPTDMQAQFCVLNALAQ
GTATITETIFENRFMHVPELIRMGATMELEGNTCIIQGIESLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRG
YEHIENKFQGLGAQVVRTQ
>Mature_419_residues
MDKLTIQASPPLAGDVIISGAKNAALPILMAGVLAETDFVVSNVPNLRDVTTSCKLLRCLGAEVTELGDGQIRISTTNLN
EFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFM
DMVSVGATENLLMAAALADGETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCNYRVMPDRIETGSF
LVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMQGKRPKAVNIKTAPYPGFPTDMQAQFCVLNALAQ
GTATITETIFENRFMHVPELIRMGATMELEGNTCIIQGIESLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRG
YEHIENKFQGLGAQVVRTQ

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=65.1551312649165, Blast_Score=562, Evalue=1e-161,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_SHEB2 (B8E9M3)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002356661.1
- ProteinModelPortal:   B8E9M3
- SMR:   B8E9M3
- GeneID:   7088111
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_0719
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44675; Mature: 44675

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLTIQASPPLAGDVIISGAKNAALPILMAGVLAETDFVVSNVPNLRDVTTSCKLLRCL
CCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHH
GAEVTELGDGQIRISTTNLNEFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIG
CCHHHCCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
ARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFMDMVSVGATENLLMAAALADG
CEEEEEEEECHHHCCCEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCHHEEEEECCCC
ETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCNYRVMPDRIETGSF
HHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCEEEEEEEHHHHCCCCEEECCCCCCCCCE
LVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMQGKRPKAVNIKTAP
EEEEECCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCEEEEECCC
YPGFPTDMQAQFCVLNALAQGTATITETIFENRFMHVPELIRMGATMELEGNTCIIQGIE
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCEEEECCCEEEEEEHH
SLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRGYEHIENKFQGLGAQVVRTQ
CCCCCEEEEHHHHCCCEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MDKLTIQASPPLAGDVIISGAKNAALPILMAGVLAETDFVVSNVPNLRDVTTSCKLLRCL
CCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHH
GAEVTELGDGQIRISTTNLNEFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIG
CCHHHCCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
ARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFMDMVSVGATENLLMAAALADG
CEEEEEEEECHHHCCCEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCHHEEEEECCCC
ETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCNYRVMPDRIETGSF
HHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCEEEEEEEHHHHCCCCEEECCCCCCCCCE
LVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMQGKRPKAVNIKTAP
EEEEECCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCEEEEECCC
YPGFPTDMQAQFCVLNALAQGTATITETIFENRFMHVPELIRMGATMELEGNTCIIQGIE
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCEEEECCCEEEEEEHH
SLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRGYEHIENKFQGLGAQVVRTQ
CCCCCEEEEHHHHCCCEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA