Click here to switch to the map view.

The map label for this gene is cvrA [H]

Identifier: 126175622

GI number: 126175622

Start: 4014368

End: 4016098

Strand: Reverse

Name: cvrA [H]

Synonym: Sbal_3425

Alternate gene names: 126175622

Gene position: 4016098-4014368 (Counterclockwise)

Preceding gene: 126175623

Following gene: 126175620

Centisome position: 78.33

GC content: 49.57

Gene sequence:

>1731_bases
GTGGATGCAAATTCCATCAATAGTTTTTTTCTGATTGGCGCCTTGCTAACTGCAGTGAGTGTTTTACTCAGTCCCATGTC
TTCCCGTTTGGGTATCCCGATTCTTTTGATCTTCCTCGCCGTGGGTATTTTGGCCGGTGAAGATGGCCCTGGCGGAATAT
TGTTTGATGATTATTCCACCGCTTATTTAGTCAGTAACTTAGCGCTTGCTATCATCTTACTCGATGGTGGTATGCGTACC
CGTGTCGCCAGTTTTAGGGTGGCACTGTGGCCTGCATTATCGCTAGCGACCTTTGGCGTCGCGATCACAACCAGTATCAC
TGGCATGATGGCCGCTTGGCTGTTTGACTTGCATTGGTTGCAAGGTTTGCTGGTGGGCGCGATTGTGGGCTCGACCGATG
CCGCTGCGGTATTCTCCTTATTGAAAGGGCGCAGTCTCAATGAGCGGGTTGGGGCAACCTTAGAAATCGAGTCCGGTAGT
AACGACCCTATGGCGGTGTTTTTAACCGTGACGCTGATTGCGATTCTCGCCAATGTGGACACTGAGATGTCCTTCAGCTT
TATGTTTATCAGCTTTATTAAGCAATTTGGTCTGGGTATTTGCTTAGGTTTAGGTGGCGGCTGGATGTTGTGGAAGCTGG
TTAATTTGAGCAAATTAGCCGACGGCCTGTACTCTATTTTAGTCTTAAGCGGTGGTCTGATTATTTATGCTGCGTCTAAC
AAACTCGGCGGCAGTGGCATTTTATCGATTTACTTAGTCGGGCTTTTCCTCGGCAATAAGCCGACCCGTGGTCGCCATGC
GATTTTAAACGTACTGGATGGCATGACTTGGGTCAGCCAAATCGGCATGTTCTTGGTATTAGGCCTATTGCTTACCCCTT
CAGATTTAGTCGATATCCTGATCCCAGGTTTTGCGCTGGCATTTGGGATGATTCTATTCGCCCGTCCTGTCGCTGTGTGG
ATCAGCCTATTGCCCTTTAAGAGCTTCAGCAGTCGCGACCGCTGGTTTATTTCGTGGGTAGGACTACGCGGTGCTGTACC
TATCATCTTAGCGGTATTCCCCATGATGGCCGGCTTGCCGGGTGCTCAGTTGTACTTCAACTTAGCCTTCTTCGTCGTAT
TAGTATCGTTACTGGTTCAAGGTGCGTCTTTGACCACTGCGGCGCGTTTAGCTAAGGTGGAACTGCCCCCAAAGCCGTTG
CCCGTTTCGCGTTCGGGAGTTGAAATTTACCCGAGCAGCGAATGGGAAGTGTTTGTCTATCGTTTGAGTGAAAGTAAGTG
GTGTATTGGTGAGCCGCTAAAACGCTTAGCGATGCCTGATGGAACACGGATTGCGGCGGTATTTAGGAATGACACTTTAC
TGCATCCGTCGGGCAGTACTCGCCTCGAAGCGGGAGATATACTCTGTGTGCTGGGTCAGGAGAAAAGTTTAGAAGCCTTG
AGTAACCTCTTTAGCCAAGCGCCTGAAAATAAAGAAGTGCAACGCTTCTTCGGTGATTTCTTTATTGAAACAGACGTTAA
GCTTGCGGATCTCGCACCAATTTATGGCTTGAGCTTAGATAATCTCGCCGATGATATGACAGTCGCCGATCTGGTGGTGT
CACAGCTTGGCGCCAATCCTGTGCTGGGCGATCAGTTCCAATGGCAGTCGTTGCATTGGGTGGTGGCGGGGCTGTATGAA
GGCAAAGTCACTAACGTGGGTATTCGTTTACCGACTGAGCATGCGCTGTAA

Upstream 100 bases:

>100_bases
TTTTGTGCTAATATAAAATCATAAAATTGTAAGTTGAGTCATTTTTAACCTCGGTGATTTGTCTATCGTTTAACTAAACA
ACCTGTATAAGGAGGCGTTT

Downstream 100 bases:

>100_bases
TCTCATGCGCTAGATGCTTCTTTCCATATAGAGTTGCCATAGAGAGTTGAAGTTGAAAGTTGTCATCGATAATTGCCATT
GAAAGTTATCATCGACGATT

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNLALAIILLDGGMRT
RVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGS
NDPMAVFLTVTLIAILANVDTEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASN
KLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDILIPGFALAFGMILFARPVAVW
ISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPL
PVSRSGVEIYPSSEWEVFVYRLSESKWCIGEPLKRLAMPDGTRIAAVFRNDTLLHPSGSTRLEAGDILCVLGQEKSLEAL
SNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVSQLGANPVLGDQFQWQSLHWVVAGLYE
GKVTNVGIRLPTEHAL

Sequences:

>Translated_576_residues
MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNLALAIILLDGGMRT
RVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGS
NDPMAVFLTVTLIAILANVDTEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASN
KLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDILIPGFALAFGMILFARPVAVW
ISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPL
PVSRSGVEIYPSSEWEVFVYRLSESKWCIGEPLKRLAMPDGTRIAAVFRNDTLLHPSGSTRLEAGDILCVLGQEKSLEAL
SNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVSQLGANPVLGDQFQWQSLHWVVAGLYE
GKVTNVGIRLPTEHAL
>Mature_576_residues
MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNLALAIILLDGGMRT
RVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGS
NDPMAVFLTVTLIAILANVDTEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASN
KLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDILIPGFALAFGMILFARPVAVW
ISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPL
PVSRSGVEIYPSSEWEVFVYRLSESKWCIGEPLKRLAMPDGTRIAAVFRNDTLLHPSGSTRLEAGDILCVLGQEKSLEAL
SNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVSQLGANPVLGDQFQWQSLHWVVAGLYE
GKVTNVGIRLPTEHAL

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=577, Percent_Identity=59.6187175043327, Blast_Score=612, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 61942; Mature: 61942

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEECCCCH
AYLVSNLALAIILLDGGMRTRVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWL
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGSNDPMAVFLTVTLIAILANVD
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
TEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASN
CCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC
KLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDIL
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IPGFALAFGMILFARPVAVWISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
GAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPLPVSRSGVEIYPSSEWEVFVY
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCEEEEECCCCEEEEE
RLSESKWCIGEPLKRLAMPDGTRIAAVFRNDTLLHPSGSTRLEAGDILCVLGQEKSLEAL
EECCCCCCHHHHHHHHCCCCCCEEEEEEECCEEECCCCCCEEECCCEEEEECCCCCHHHH
SNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVSQLGANP
HHHHHCCCCCHHHHHHHHHHHEECCCCHHHCCCHHCCCHHHHHHHHHHHHHHHHHHCCCC
VLGDQFQWQSLHWVVAGLYEGKVTNVGIRLPTEHAL
CCCCCCCHHHHHHHHHHHCCCCEEEEEEECCHHCCC
>Mature Secondary Structure
MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEECCCCH
AYLVSNLALAIILLDGGMRTRVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWL
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGSNDPMAVFLTVTLIAILANVD
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
TEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASN
CCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC
KLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDIL
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IPGFALAFGMILFARPVAVWISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
GAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPLPVSRSGVEIYPSSEWEVFVY
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCEEEEECCCCEEEEE
RLSESKWCIGEPLKRLAMPDGTRIAAVFRNDTLLHPSGSTRLEAGDILCVLGQEKSLEAL
EECCCCCCHHHHHHHHCCCCCCEEEEEEECCEEECCCCCCEEECCCEEEEECCCCCHHHH
SNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVSQLGANP
HHHHHCCCCCHHHHHHHHHHHEECCCCHHHCCCHHCCCHHHHHHHHHHHHHHHHHHCCCC
VLGDQFQWQSLHWVVAGLYEGKVTNVGIRLPTEHAL
CCCCCCCHHHHHHHHHHHCCCCEEEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA