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The map label for this gene is ntrY [H]

Identifier: 126175535

GI number: 126175535

Start: 3900717

End: 3902405

Strand: Reverse

Name: ntrY [H]

Synonym: Sbal_3337

Alternate gene names: 126175535

Gene position: 3902405-3900717 (Counterclockwise)

Preceding gene: 126175536

Following gene: 126175534

Centisome position: 76.11

GC content: 47.01

Gene sequence:

>1689_bases
GTGTTAATTCGAACTAAACTGATCATTTATTCAATGGCTTGCTGCGCCTTTGGCGTCTTGCTCAGCTTCGCCTTAGTGAA
ATATTTCTCACCTAATGCTTCGTCTGTTACCACGCCTAACTCGATCGAAATCCCTGATGTGAATGTGCAACTCGATTTTG
CGGAGCTGGAGAAAACCGTCGCTTCCATCGAGCTTGCCCTTAAAAATACAGAACAATTACAGCTGATGGCAGCCATGCAA
GCGCGCCAGAGGACCGAGCAGATTAAGGCAGAACTGCAAAAGCTTGAACAACTTAAACAAGAGCAGTTACAGATAAAACT
CTTCAAGTTAGAACAGCTTAAAGAAGGGCAGTTTAATTTCACCGCTCATATTGCTGATCCTTTACGTGTAGAACCGCTAT
CCATTTTACCGCACAAAGCCCCTGTATCCCCAGTGGCGCCCGCTGAAATAGCAGACAACGAGCGAGTCTCGAGTTTAACC
TTAGGTGAAGGTTTGCTGGTGTTATTGCTCGCTTGTGGAGCGTGTGGACTAAGTGTCGCTTGGTTAACACGGCATCTGGG
TCGTAGTTTGGACTCCCTCGAAATAGGTCTACTGAACTTTAGCGATAATGACTTTAGCGTGAGTATTCAAGAGTATGGTG
AAGGTCAGCTCAAAACCTTGGCCCAGTTATTTAATCATTCGGCGGCAAAATTGCGCCAAGAAAGGCAATACATTTACCAG
CGTGAGTTATTGCTGGATAAGGTGATCCAAAGCTCTCCCAACGTGATGTTATTGCTCGACGACCATCAGCGGCTCATTTA
CGCCAACGATGCGGCGCGTCACCTATTCCACAAAAAGGGCAAAATGGAAGGTTTGAGCCTAGATGAATTGTTAGTGGACT
TGCCCGAAGTATTGGCCTTAGCGCTTAAACATGAAAAGAACGGTCTCTTTGCCATGGGCGAAGATGATGTGGAAACCTGG
TATTTGAGTCGTGGCCAATTTTTGTTAAATAACCAACAACATAACTTGATTTTACTTAAGCAGATGACCCGCGAGCTTAA
TCGTCAAGAGGTGGCAGTGTGGAAGAAAGTGATCCGCATTATTAGCCATGAACTCAATAACTCAGTGGCGCCCATCGCCT
CTATGGTGAACTCCGGCCGACTGCTCACCAAAGATATCGATAATCCCAAGTTAACCTTGATTTTCGATACGATCGAGAAT
CGCACCAGTCATCTGAGCCAGTTTATCTTCAACTATGCCCGCTTTGCTAAGTTGCCGCTCCCGCAGCGGCGTCAGGTGAA
TTGGACGCAATTTACGACCCAGTTAACCCAGCATTATCCCTTTAAACTTAGGCATGATTTGCCTGAGGTTGATGGTTATT
TCGACCAAGGACAGATGGAGCAAGTGCTACTCAACTTGCTTAAAAACGCCCATGAATCGGGTTCAAACCCAGAGGATGTC
ACCCTGTCGATTCGGTATCAAACCTTAGTGGATGGTGCTGGTTTCAGTATTGCGATCGAGGATCGCGGTACTGGCATGTC
TGGCGAGGTCTTAGAGCAAGCGCTGTTGCCATTTTACTCCACGAAACAATCGGGTACTGGGCTTGGTCTACCTCTGTGCC
GTGAAATTATCGAAGCCCACGATGGCAGTATTAGCATGCATAATCGCAGCGACGGCGGCCTGTTGGTTCGGCTGTGGTTA
CCACAATAA

Upstream 100 bases:

>100_bases
AGTCGTCAGGCGCTGTATCGGCGCATGGATAAGTTTGGTTTAGATAAGTCATAGGCCACAGATGCTAGGCCACAGAAAGG
CTATCGATTAAGGAATGTGA

Downstream 100 bases:

>100_bases
TCCGCACGTTTTGTATCAGCACAGCAATGCGACCCTGGGGTCGCATTTTTATTGCTTCTTCATTTGTTCGTTTACCCTAT
GACTCCGGTCTTAACGGCTT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MLIRTKLIIYSMACCAFGVLLSFALVKYFSPNASSVTTPNSIEIPDVNVQLDFAELEKTVASIELALKNTEQLQLMAAMQ
ARQRTEQIKAELQKLEQLKQEQLQIKLFKLEQLKEGQFNFTAHIADPLRVEPLSILPHKAPVSPVAPAEIADNERVSSLT
LGEGLLVLLLACGACGLSVAWLTRHLGRSLDSLEIGLLNFSDNDFSVSIQEYGEGQLKTLAQLFNHSAAKLRQERQYIYQ
RELLLDKVIQSSPNVMLLLDDHQRLIYANDAARHLFHKKGKMEGLSLDELLVDLPEVLALALKHEKNGLFAMGEDDVETW
YLSRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNNSVAPIASMVNSGRLLTKDIDNPKLTLIFDTIEN
RTSHLSQFIFNYARFAKLPLPQRRQVNWTQFTTQLTQHYPFKLRHDLPEVDGYFDQGQMEQVLLNLLKNAHESGSNPEDV
TLSIRYQTLVDGAGFSIAIEDRGTGMSGEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGSISMHNRSDGGLLVRLWL
PQ

Sequences:

>Translated_562_residues
MLIRTKLIIYSMACCAFGVLLSFALVKYFSPNASSVTTPNSIEIPDVNVQLDFAELEKTVASIELALKNTEQLQLMAAMQ
ARQRTEQIKAELQKLEQLKQEQLQIKLFKLEQLKEGQFNFTAHIADPLRVEPLSILPHKAPVSPVAPAEIADNERVSSLT
LGEGLLVLLLACGACGLSVAWLTRHLGRSLDSLEIGLLNFSDNDFSVSIQEYGEGQLKTLAQLFNHSAAKLRQERQYIYQ
RELLLDKVIQSSPNVMLLLDDHQRLIYANDAARHLFHKKGKMEGLSLDELLVDLPEVLALALKHEKNGLFAMGEDDVETW
YLSRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNNSVAPIASMVNSGRLLTKDIDNPKLTLIFDTIEN
RTSHLSQFIFNYARFAKLPLPQRRQVNWTQFTTQLTQHYPFKLRHDLPEVDGYFDQGQMEQVLLNLLKNAHESGSNPEDV
TLSIRYQTLVDGAGFSIAIEDRGTGMSGEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGSISMHNRSDGGLLVRLWL
PQ
>Mature_562_residues
MLIRTKLIIYSMACCAFGVLLSFALVKYFSPNASSVTTPNSIEIPDVNVQLDFAELEKTVASIELALKNTEQLQLMAAMQ
ARQRTEQIKAELQKLEQLKQEQLQIKLFKLEQLKEGQFNFTAHIADPLRVEPLSILPHKAPVSPVAPAEIADNERVSSLT
LGEGLLVLLLACGACGLSVAWLTRHLGRSLDSLEIGLLNFSDNDFSVSIQEYGEGQLKTLAQLFNHSAAKLRQERQYIYQ
RELLLDKVIQSSPNVMLLLDDHQRLIYANDAARHLFHKKGKMEGLSLDELLVDLPEVLALALKHEKNGLFAMGEDDVETW
YLSRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNNSVAPIASMVNSGRLLTKDIDNPKLTLIFDTIEN
RTSHLSQFIFNYARFAKLPLPQRRQVNWTQFTTQLTQHYPFKLRHDLPEVDGYFDQGQMEQVLLNLLKNAHESGSNPEDV
TLSIRYQTLVDGAGFSIAIEDRGTGMSGEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGSISMHNRSDGGLLVRLWL
PQ

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=333, Percent_Identity=26.1261261261261, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790436, Length=121, Percent_Identity=33.0578512396694, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788549, Length=239, Percent_Identity=29.2887029288703, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63368; Mature: 63368

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRTKLIIYSMACCAFGVLLSFALVKYFSPNASSVTTPNSIEIPDVNVQLDFAELEKTV
CEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEEEHHHHHHHH
ASIELALKNTEQLQLMAAMQARQRTEQIKAELQKLEQLKQEQLQIKLFKLEQLKEGQFNF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
TAHIADPLRVEPLSILPHKAPVSPVAPAEIADNERVSSLTLGEGLLVLLLACGACGLSVA
EEEECCCCEECCHHHCCCCCCCCCCCCCHHCCCCCCCEEEHHHHHHHHHHHHCCCCHHHH
WLTRHLGRSLDSLEIGLLNFSDNDFSVSIQEYGEGQLKTLAQLFNHSAAKLRQERQYIYQ
HHHHHHCCCCCCEEEEEEEECCCCEEEEHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHH
RELLLDKVIQSSPNVMLLLDDHQRLIYANDAARHLFHKKGKMEGLSLDELLVDLPEVLAL
HHHHHHHHHHCCCCEEEEEECCCEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
ALKHEKNGLFAMGEDDVETWYLSRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRI
HHHHCCCCEEEECCCCHHHHEEECCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
ISHELNNSVAPIASMVNSGRLLTKDIDNPKLTLIFDTIENRTSHLSQFIFNYARFAKLPL
HHHHHCCCHHHHHHHHCCCCEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCC
PQRRQVNWTQFTTQLTQHYPFKLRHDLPEVDGYFDQGQMEQVLLNLLKNAHESGSNPEDV
CCCCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCE
TLSIRYQTLVDGAGFSIAIEDRGTGMSGEVLEQALLPFYSTKQSGTGLGLPLCREIIEAH
EEEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHC
DGSISMHNRSDGGLLVRLWLPQ
CCCEEECCCCCCCEEEEEECCC
>Mature Secondary Structure
MLIRTKLIIYSMACCAFGVLLSFALVKYFSPNASSVTTPNSIEIPDVNVQLDFAELEKTV
CEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEEEHHHHHHHH
ASIELALKNTEQLQLMAAMQARQRTEQIKAELQKLEQLKQEQLQIKLFKLEQLKEGQFNF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
TAHIADPLRVEPLSILPHKAPVSPVAPAEIADNERVSSLTLGEGLLVLLLACGACGLSVA
EEEECCCCEECCHHHCCCCCCCCCCCCCHHCCCCCCCEEEHHHHHHHHHHHHCCCCHHHH
WLTRHLGRSLDSLEIGLLNFSDNDFSVSIQEYGEGQLKTLAQLFNHSAAKLRQERQYIYQ
HHHHHHCCCCCCEEEEEEEECCCCEEEEHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHH
RELLLDKVIQSSPNVMLLLDDHQRLIYANDAARHLFHKKGKMEGLSLDELLVDLPEVLAL
HHHHHHHHHHCCCCEEEEEECCCEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
ALKHEKNGLFAMGEDDVETWYLSRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRI
HHHHCCCCEEEECCCCHHHHEEECCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
ISHELNNSVAPIASMVNSGRLLTKDIDNPKLTLIFDTIENRTSHLSQFIFNYARFAKLPL
HHHHHCCCHHHHHHHHCCCCEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCC
PQRRQVNWTQFTTQLTQHYPFKLRHDLPEVDGYFDQGQMEQVLLNLLKNAHESGSNPEDV
CCCCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCE
TLSIRYQTLVDGAGFSIAIEDRGTGMSGEVLEQALLPFYSTKQSGTGLGLPLCREIIEAH
EEEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHC
DGSISMHNRSDGGLLVRLWLPQ
CCCEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]