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The map label for this gene is serB [H]

Identifier: 126175422

GI number: 126175422

Start: 3776951

End: 3777931

Strand: Reverse

Name: serB [H]

Synonym: Sbal_3222

Alternate gene names: 126175422

Gene position: 3777931-3776951 (Counterclockwise)

Preceding gene: 126175424

Following gene: 126175421

Centisome position: 73.68

GC content: 50.36

Gene sequence:

>981_bases
ATGGAAAGCTTGAACCAAGATGCGCTTTTTTTGTGGTTAGTCTCTGACCATTCCCCAAGGTTTGAACGCCAAGGGCAAGT
ATTTGAACGTTATCAAGAGTCAGCAACCCCCGCTGGTGTTTCGCGTTTGCGGATTATCTATCAAGATACGTTAGCGCAGG
CAGCGATATCGGCCTTGATTGCGGCATTGCCTTCGTCTGACGTTATCGGTATTGCCCATATCGAACGCCAAGTTGGCTTA
CATTGCATCGAGTTGGCGCTGGTGAATATGCCTTCTCAGGCGCAGTTAGCGGCGTTCCCTCAGTCTTTGGCTGAACTGCA
TGTGCTCCATGTTGATTTGCCTCGCTTGAATCATCCCGGCTTATTAGTGATGGACATGGATTCCACAGCGATTCAGATTG
AATGTATTGATGAATTAGCGGCCATGGCGGGCGTTGGCGAGCGCGTGGCGGCGATTACTGAACGTGCTATGCAAGGTGAG
CTGGATTTTGAACAGAGTCTACGTCAGCGCGTGGCACAGCTTAAGGGCGCCGATGCCAGTATTATTACAACTTTGTGCGA
TAACTTGCCTTTAATGCCAGGGCTTGAGCCCATGCTTTTGGAGCTTAAATCCCATGGCTGGCGTTTAGTGGTGGCATCTG
GCGGTTTTACCCCTTTTGTGGGCCATTTAAAGCAGCTGTTAAGCCTAGATGCGGCCTTTGCTAATGAGTTAGTCATCACT
GATGGCAAACTCGCGGGTGAAGTGACGGGTAAAGTGGTGGATGCGCAGTTTAAGGCGGATGTGGTTAAGCGTTGCAGTGA
GCAGTGGGACATTCCAAAAGGCCAAAGAGTTGCTATCGGTGATGGTGCGAATGATATCCCTATGGTGATGGCGGCGGATT
TTGGTATTGCTTTCCATGCCAAACCTAAGCTGGTAGCCGCGGCGGATGCGAATATTCGCCACCTCGACCTGCGCGTTTTA
CCTTATCTGTTGCAAATCTAG

Upstream 100 bases:

>100_bases
TAGCCCTTTAAGATATAACACTTTGACCCTTAAAATGTAGAGCGCTTGCCTAATCATAATTGATTCTGAGTGAGCCCGAT
AGTTGGAGAATTTAAGTCCG

Downstream 100 bases:

>100_bases
GTTATTCATTTACTTGAAATTTAAGTTGAGATGAAAGTCTAAGTAATGGCTGAGTTAGAGTAATGACTCTTGTCTTTTAT
CGATGAACTGGTAGTTTAGG

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MESLNQDALFLWLVSDHSPRFERQGQVFERYQESATPAGVSRLRIIYQDTLAQAAISALIAALPSSDVIGIAHIERQVGL
HCIELALVNMPSQAQLAAFPQSLAELHVLHVDLPRLNHPGLLVMDMDSTAIQIECIDELAAMAGVGERVAAITERAMQGE
LDFEQSLRQRVAQLKGADASIITTLCDNLPLMPGLEPMLLELKSHGWRLVVASGGFTPFVGHLKQLLSLDAAFANELVIT
DGKLAGEVTGKVVDAQFKADVVKRCSEQWDIPKGQRVAIGDGANDIPMVMAADFGIAFHAKPKLVAAADANIRHLDLRVL
PYLLQI

Sequences:

>Translated_326_residues
MESLNQDALFLWLVSDHSPRFERQGQVFERYQESATPAGVSRLRIIYQDTLAQAAISALIAALPSSDVIGIAHIERQVGL
HCIELALVNMPSQAQLAAFPQSLAELHVLHVDLPRLNHPGLLVMDMDSTAIQIECIDELAAMAGVGERVAAITERAMQGE
LDFEQSLRQRVAQLKGADASIITTLCDNLPLMPGLEPMLLELKSHGWRLVVASGGFTPFVGHLKQLLSLDAAFANELVIT
DGKLAGEVTGKVVDAQFKADVVKRCSEQWDIPKGQRVAIGDGANDIPMVMAADFGIAFHAKPKLVAAADANIRHLDLRVL
PYLLQI
>Mature_326_residues
MESLNQDALFLWLVSDHSPRFERQGQVFERYQESATPAGVSRLRIIYQDTLAQAAISALIAALPSSDVIGIAHIERQVGL
HCIELALVNMPSQAQLAAFPQSLAELHVLHVDLPRLNHPGLLVMDMDSTAIQIECIDELAAMAGVGERVAAITERAMQGE
LDFEQSLRQRVAQLKGADASIITTLCDNLPLMPGLEPMLLELKSHGWRLVVASGGFTPFVGHLKQLLSLDAAFANELVIT
DGKLAGEVTGKVVDAQFKADVVKRCSEQWDIPKGQRVAIGDGANDIPMVMAADFGIAFHAKPKLVAAADANIRHLDLRVL
PYLLQI

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=197, Percent_Identity=31.9796954314721, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1790849, Length=205, Percent_Identity=60, Blast_Score=255, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI115534456, Length=186, Percent_Identity=30.1075268817204, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534454, Length=186, Percent_Identity=30.1075268817204, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=222, Percent_Identity=40.0900900900901, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35415; Mature: 35415

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLNQDALFLWLVSDHSPRFERQGQVFERYQESATPAGVSRLRIIYQDTLAQAAISALI
CCCCCCCEEEEEEEECCCCCHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AALPSSDVIGIAHIERQVGLHCIELALVNMPSQAQLAAFPQSLAELHVLHVDLPRLNHPG
HHCCCCCEEEHHHHHHHHHHHEEEHHHHCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCC
LLVMDMDSTAIQIECIDELAAMAGVGERVAAITERAMQGELDFEQSLRQRVAQLKGADAS
EEEEECCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHH
IITTLCDNLPLMPGLEPMLLELKSHGWRLVVASGGFTPFVGHLKQLLSLDAAFANELVIT
HHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEE
DGKLAGEVTGKVVDAQFKADVVKRCSEQWDIPKGQRVAIGDGANDIPMVMAADFGIAFHA
CCCCCCHHHCCEEHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCCEEEEC
KPKLVAAADANIRHLDLRVLPYLLQI
CCCEEEECCCCEEEEHHHHHHHHHCC
>Mature Secondary Structure
MESLNQDALFLWLVSDHSPRFERQGQVFERYQESATPAGVSRLRIIYQDTLAQAAISALI
CCCCCCCEEEEEEEECCCCCHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AALPSSDVIGIAHIERQVGLHCIELALVNMPSQAQLAAFPQSLAELHVLHVDLPRLNHPG
HHCCCCCEEEHHHHHHHHHHHEEEHHHHCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCC
LLVMDMDSTAIQIECIDELAAMAGVGERVAAITERAMQGELDFEQSLRQRVAQLKGADAS
EEEEECCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHH
IITTLCDNLPLMPGLEPMLLELKSHGWRLVVASGGFTPFVGHLKQLLSLDAAFANELVIT
HHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEE
DGKLAGEVTGKVVDAQFKADVVKRCSEQWDIPKGQRVAIGDGANDIPMVMAADFGIAFHA
CCCCCCHHHCCEEHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCCEEEEC
KPKLVAAADANIRHLDLRVLPYLLQI
CCCEEEECCCCEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]