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The map label for this gene is bepF [H]

Identifier: 126175383

GI number: 126175383

Start: 3727939

End: 3729177

Strand: Reverse

Name: bepF [H]

Synonym: Sbal_3182

Alternate gene names: 126175383

Gene position: 3729177-3727939 (Counterclockwise)

Preceding gene: 126175385

Following gene: 126175382

Centisome position: 72.73

GC content: 50.12

Gene sequence:

>1239_bases
ATGAAGAGCAATAAACCCTTACGAATAATGATGTTAACGGCTGTGGCCGCTTTCGTTCTGTCAGCTTGTGGTGAGCAAAC
AGCGCAGCAGGGGCCAGCACCAAGTGCGCCTATGGTGGATGTCGCCCAAGTATTGCATGAGCGAGTGACCGAATGGGACG
AGTTTACCGGCCGTTTACAGGCGCCAGAAAGTGTCACACTTATCCCGCGTGTATCTGGATATATCGACTCAGTGAATTTT
AAAGAAGGCGCCTTAGTGAAAAAAGGCGACGTATTATTCCGCATCGATCCAAGTGTTTTTGAAGTGGAAGTGGCCCGGTT
AAAAGCAGATCTTGCTAGCGCACTCTCTGCAGAGCAACTGGCCACAAATGACTTTGAACGAGCCCATAAATTGTTTGACC
AAAAAGCGGTGTCTGCCGAGTTACTCGATACCCGTGAGTCAAACAAACGTCAGACCGCGGCTGCAGTGGCTTCGGTGAAA
GCGGCCCTGATGCGCGCCGAGCTTGATTTAGCTTATACCCAAGTGCAAGCGCCGATTGATGGTCGCGTGTCCTACGCAAA
TGTCACTGCGGGCAATTATGTCACCGCAGGGCAGAGTGTGCTGACCAGCTTAGTCTCTACCGCCAGCATGTATGCCTATT
TCGATGTGGATGAGCAAACCTATCTTAAATACGTGAAATTAACGGCCGAGAAGAAACGTAACGATCCCCGCGCTGGCGAC
AACCCTGTGTACATGGCTTTAGCCAATGAACGTGATTATCAACATATCGGTATGGTCGACTTTGTGGATAATGCGATGGA
TAAGCAAACAGGCACCATTCGCGTGAGAGCTTCTTTTGACAATGAAGACAATAGCTTATTGCCTGGCTTGTTTGCCCGCC
TTCGCACCGCAGGTAGCGGCGCTTATGAAGGTATCTTGATTGACGATAAAGCCGTTGGTACAGATCTGAACAATAAGTTT
GTGTTAGTGGTGGGCGCCGATGGTTTAGTTGAATATCGCGGCGTGACCTTAGGCGAGAAAGTCCAAGGACTGCGCATCGT
GACCCAAGGTTTGATGGCCGAAGACAAGATCGTCGTCAACGGTATGCAGCGCGTGCGTCCTAAGATGCAAATTGATCCGC
ACATGGTTGAAATGGTCGACAGCGACAAGCTCGAAGCATTACGCCAAGCCCAGTTAATCCTAGATAAAAACCAAGATACT
TTGACGGCGCAAGCGGTCGAAACGGCTAGCCGCGGTTAA

Upstream 100 bases:

>100_bases
CTATATATTACCGTCCAGTACAGAATATTTTTTACCAGTCGGTATTTAAATGTGTGTGGTTCGAACAGCGTGACATGCCC
GCCACTTTGAGGATAGTAAT

Downstream 100 bases:

>100_bases
GGAATAGAACACCATGTTATCGCAGTTTTTTATTAAAAGACCGATATTTGCAGCCGTACTCTCACTGCTGTTTTTTATCA
CAGGGGCGATTGCCGTTTGG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKSNKPLRIMMLTAVAAFVLSACGEQTAQQGPAPSAPMVDVAQVLHERVTEWDEFTGRLQAPESVTLIPRVSGYIDSVNF
KEGALVKKGDVLFRIDPSVFEVEVARLKADLASALSAEQLATNDFERAHKLFDQKAVSAELLDTRESNKRQTAAAVASVK
AALMRAELDLAYTQVQAPIDGRVSYANVTAGNYVTAGQSVLTSLVSTASMYAYFDVDEQTYLKYVKLTAEKKRNDPRAGD
NPVYMALANERDYQHIGMVDFVDNAMDKQTGTIRVRASFDNEDNSLLPGLFARLRTAGSGAYEGILIDDKAVGTDLNNKF
VLVVGADGLVEYRGVTLGEKVQGLRIVTQGLMAEDKIVVNGMQRVRPKMQIDPHMVEMVDSDKLEALRQAQLILDKNQDT
LTAQAVETASRG

Sequences:

>Translated_412_residues
MKSNKPLRIMMLTAVAAFVLSACGEQTAQQGPAPSAPMVDVAQVLHERVTEWDEFTGRLQAPESVTLIPRVSGYIDSVNF
KEGALVKKGDVLFRIDPSVFEVEVARLKADLASALSAEQLATNDFERAHKLFDQKAVSAELLDTRESNKRQTAAAVASVK
AALMRAELDLAYTQVQAPIDGRVSYANVTAGNYVTAGQSVLTSLVSTASMYAYFDVDEQTYLKYVKLTAEKKRNDPRAGD
NPVYMALANERDYQHIGMVDFVDNAMDKQTGTIRVRASFDNEDNSLLPGLFARLRTAGSGAYEGILIDDKAVGTDLNNKF
VLVVGADGLVEYRGVTLGEKVQGLRIVTQGLMAEDKIVVNGMQRVRPKMQIDPHMVEMVDSDKLEALRQAQLILDKNQDT
LTAQAVETASRG
>Mature_412_residues
MKSNKPLRIMMLTAVAAFVLSACGEQTAQQGPAPSAPMVDVAQVLHERVTEWDEFTGRLQAPESVTLIPRVSGYIDSVNF
KEGALVKKGDVLFRIDPSVFEVEVARLKADLASALSAEQLATNDFERAHKLFDQKAVSAELLDTRESNKRQTAAAVASVK
AALMRAELDLAYTQVQAPIDGRVSYANVTAGNYVTAGQSVLTSLVSTASMYAYFDVDEQTYLKYVKLTAEKKRNDPRAGD
NPVYMALANERDYQHIGMVDFVDNAMDKQTGTIRVRASFDNEDNSLLPGLFARLRTAGSGAYEGILIDDKAVGTDLNNKF
VLVVGADGLVEYRGVTLGEKVQGLRIVTQGLMAEDKIVVNGMQRVRPKMQIDPHMVEMVDSDKLEALRQAQLILDKNQDT
LTAQAVETASRG

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786668, Length=379, Percent_Identity=33.509234828496, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789929, Length=370, Percent_Identity=28.9189189189189, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1789665, Length=377, Percent_Identity=30.5039787798408, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI87082036, Length=350, Percent_Identity=28.2857142857143, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI87081951, Length=172, Percent_Identity=35.4651162790698, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789637, Length=164, Percent_Identity=34.1463414634146, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790519, Length=216, Percent_Identity=26.3888888888889, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 45029; Mature: 45029

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNKPLRIMMLTAVAAFVLSACGEQTAQQGPAPSAPMVDVAQVLHERVTEWDEFTGRLQ
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
APESVTLIPRVSGYIDSVNFKEGALVKKGDVLFRIDPSVFEVEVARLKADLASALSAEQL
CCCCEEEEECCCCCCCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
ATNDFERAHKLFDQKAVSAELLDTRESNKRQTAAAVASVKAALMRAELDLAYTQVQAPID
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
GRVSYANVTAGNYVTAGQSVLTSLVSTASMYAYFDVDEQTYLKYVKLTAEKKRNDPRAGD
CCEEEEEEECCCEEECCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHCCCCCCCC
NPVYMALANERDYQHIGMVDFVDNAMDKQTGTIRVRASFDNEDNSLLPGLFARLRTAGSG
CCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCC
AYEGILIDDKAVGTDLNNKFVLVVGADGLVEYRGVTLGEKVQGLRIVTQGLMAEDKIVVN
CCCEEEEECHHCCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHCC
GMQRVRPKMQIDPHMVEMVDSDKLEALRQAQLILDKNQDTLTAQAVETASRG
CHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKSNKPLRIMMLTAVAAFVLSACGEQTAQQGPAPSAPMVDVAQVLHERVTEWDEFTGRLQ
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
APESVTLIPRVSGYIDSVNFKEGALVKKGDVLFRIDPSVFEVEVARLKADLASALSAEQL
CCCCEEEEECCCCCCCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
ATNDFERAHKLFDQKAVSAELLDTRESNKRQTAAAVASVKAALMRAELDLAYTQVQAPID
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
GRVSYANVTAGNYVTAGQSVLTSLVSTASMYAYFDVDEQTYLKYVKLTAEKKRNDPRAGD
CCEEEEEEECCCEEECCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHCCCCCCCC
NPVYMALANERDYQHIGMVDFVDNAMDKQTGTIRVRASFDNEDNSLLPGLFARLRTAGSG
CCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCC
AYEGILIDDKAVGTDLNNKFVLVVGADGLVEYRGVTLGEKVQGLRIVTQGLMAEDKIVVN
CCCEEEEECHHCCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHCC
GMQRVRPKMQIDPHMVEMVDSDKLEALRQAQLILDKNQDTLTAQAVETASRG
CHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]