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The map label for this gene is aer [H]

Identifier: 126175288

GI number: 126175288

Start: 3611805

End: 3613373

Strand: Direct

Name: aer [H]

Synonym: Sbal_3087

Alternate gene names: 126175288

Gene position: 3611805-3613373 (Clockwise)

Preceding gene: 126175286

Following gene: 126175289

Centisome position: 70.44

GC content: 50.22

Gene sequence:

>1569_bases
ATGAGCCAGAGTAACGCGTCTGCCAACAGAACACTGAATGCACAGAGATCAGATCAAGAAATCCGCTTAACACCACAGGA
CGAACTCATCTCCACTACCGACACTCGCGGTGTTATCACTTACGTTAATGCCCGTTTTGCCGAAGTCTCAGGCTACAGCG
CCCAAGAGTTAGTCGGCAGTGCCCACAATATGGTTCGTCATCCCGATATGCCGAGCGCCGCCTTTAAAGAAATGTGGGGA
AAACTTAAATCGGGTCAATCTTGGCGCGGCATAGTGAAGAACCGTTGTAAGAATGGTGGCTTCTATTGGGTCGATGCCTT
CGTCTCGCCATTGTTTGAAAACGGCACCATTGTCGGTTATCAATCGGTGCGTATTCAGCCTCAGGCCGCCTACGTCAGCA
AGGCGAACGAGATATACCAAAGACTTAAACTGGATAAATCCATTTCTAAGCCCTTAAGCTTAATGCAGAAACGTATCCTC
TCGGCGGTTGTCGCCTCGACCGGCTTATTGATCGCAGGCTACTTTTGGGGCTGGGGCGTGATTATCGCGGGGGCGGTTTT
GATGAGTATAAACTTGGCTATATTCTACGATGAGGCCTTTCGCATTCCCGCTAAACTGATTGAAATGCAAACCAAATACG
ACTCTATCAGTCGCTACATATACTCGGGTGCCGATACGTCTTCTATCCTCGATTTCCAGCTCATCATGCTGCAAGCCAAA
ATGAATGGCGTACTGGGACGCACACAAGATCAAGCCAATCAATTGCACGCAATTGCCGATCAATTGGTGGTCGCGACCGA
GCAAACCTATGTCAGCCTAGATCAAGAAAAAAGTCAGTTAGAACAGCTCTCTGGCGCGATGGAAGAAATGAGTTCAACCA
TTACAGAAGTGGCGCAGAATACCCATCTCACATCCACCAGCATCAATACCGCCTACGATCTTTGCCTTAAAAGCAGCGCC
AATATGAAGGCCAACACTCAAAAAGTGGAACAACTCGCCAAGTCTGTTGCCGATGCCGCTAACAATGCCCACCAATTAAA
TAAAGAAGCCGAGCAAGTTGCTAATGCGATGGGCGAAATTGACTCCATCGCCGAGCAAACCAATCTTCTCGCCCTCAATG
CGGCCATTGAAGCTGCCCGTGCGGGTGAACAAGGCCGTGGGTTTGCCGTGGTCGCCGATGAAGTCCGCGCGCTGTCGAGC
CGAACCCAACTGTCGACTAACAGCATTTCAAAGAGTGTCGATAAGATGTTCACTATGCTCAACGCATGGGCCAAAGAAAT
GGAACAAAGCCGCCAACACGCTGAGCGCTGCGCTAGCGACATCCAACTGTCCGCCGACAATGTGAATACCCTTTACCAAG
AAGTGAGTGATATCCACACTTTTGCCCAGCAAAATGCGGTCGCAGCGGATCAACAGCGTCAAGTGGTCAACGAGATTGCC
AGCAACATACACTCCATCACCCATTCAAGCGCAGAGAACTTGGCCGCAACCCATCTGATTGGTGATGCCGCCCATCTGCT
TAAGCATAATGCCGAGAAAGCCCTCGGCTTGAGACGCACTTTCGGTTAG

Upstream 100 bases:

>100_bases
AACAAGCTTACCCCAATGAGAGTAAGCGCAAGAAAATTAGCGCCTAACACCGCGCCCCTGAACCCCAATGAATCATATCG
GCCCTGAATGGACACACTAA

Downstream 100 bases:

>100_bases
TCATAAGTAAGATATAAAATGCCGCAGCCAAAACTGCGGCATTTTTCGATCGCGTTCTTTTAGCCCATTCTTTGCGCCAG
CCCTCACTCAACCTAGAACA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MSQSNASANRTLNAQRSDQEIRLTPQDELISTTDTRGVITYVNARFAEVSGYSAQELVGSAHNMVRHPDMPSAAFKEMWG
KLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIVGYQSVRIQPQAAYVSKANEIYQRLKLDKSISKPLSLMQKRIL
SAVVASTGLLIAGYFWGWGVIIAGAVLMSINLAIFYDEAFRIPAKLIEMQTKYDSISRYIYSGADTSSILDFQLIMLQAK
MNGVLGRTQDQANQLHAIADQLVVATEQTYVSLDQEKSQLEQLSGAMEEMSSTITEVAQNTHLTSTSINTAYDLCLKSSA
NMKANTQKVEQLAKSVADAANNAHQLNKEAEQVANAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSS
RTQLSTNSISKSVDKMFTMLNAWAKEMEQSRQHAERCASDIQLSADNVNTLYQEVSDIHTFAQQNAVAADQQRQVVNEIA
SNIHSITHSSAENLAATHLIGDAAHLLKHNAEKALGLRRTFG

Sequences:

>Translated_522_residues
MSQSNASANRTLNAQRSDQEIRLTPQDELISTTDTRGVITYVNARFAEVSGYSAQELVGSAHNMVRHPDMPSAAFKEMWG
KLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIVGYQSVRIQPQAAYVSKANEIYQRLKLDKSISKPLSLMQKRIL
SAVVASTGLLIAGYFWGWGVIIAGAVLMSINLAIFYDEAFRIPAKLIEMQTKYDSISRYIYSGADTSSILDFQLIMLQAK
MNGVLGRTQDQANQLHAIADQLVVATEQTYVSLDQEKSQLEQLSGAMEEMSSTITEVAQNTHLTSTSINTAYDLCLKSSA
NMKANTQKVEQLAKSVADAANNAHQLNKEAEQVANAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSS
RTQLSTNSISKSVDKMFTMLNAWAKEMEQSRQHAERCASDIQLSADNVNTLYQEVSDIHTFAQQNAVAADQQRQVVNEIA
SNIHSITHSSAENLAATHLIGDAAHLLKHNAEKALGLRRTFG
>Mature_521_residues
SQSNASANRTLNAQRSDQEIRLTPQDELISTTDTRGVITYVNARFAEVSGYSAQELVGSAHNMVRHPDMPSAAFKEMWGK
LKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIVGYQSVRIQPQAAYVSKANEIYQRLKLDKSISKPLSLMQKRILS
AVVASTGLLIAGYFWGWGVIIAGAVLMSINLAIFYDEAFRIPAKLIEMQTKYDSISRYIYSGADTSSILDFQLIMLQAKM
NGVLGRTQDQANQLHAIADQLVVATEQTYVSLDQEKSQLEQLSGAMEEMSSTITEVAQNTHLTSTSINTAYDLCLKSSAN
MKANTQKVEQLAKSVADAANNAHQLNKEAEQVANAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSR
TQLSTNSISKSVDKMFTMLNAWAKEMEQSRQHAERCASDIQLSADNVNTLYQEVSDIHTFAQQNAVAADQQRQVVNEIAS
NIHSITHSSAENLAATHLIGDAAHLLKHNAEKALGLRRTFG

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=501, Percent_Identity=29.5409181636727, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI2367378, Length=227, Percent_Identity=31.2775330396476, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788195, Length=220, Percent_Identity=28.1818181818182, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787690, Length=220, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788194, Length=169, Percent_Identity=31.3609467455621, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57208; Mature: 57077

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSNASANRTLNAQRSDQEIRLTPQDELISTTDTRGVITYVNARFAEVSGYSAQELVGS
CCCCCCCCCCCCCCCCCCCCEEECCHHHHHCCCCCCCEEEEECHHHHHCCCCCHHHHHHH
AHNMVRHPDMPSAAFKEMWGKLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIVGY
HHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHCCCCEEEE
QSVRIQPQAAYVSKANEIYQRLKLDKSISKPLSLMQKRILSAVVASTGLLIAGYFWGWGV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IIAGAVLMSINLAIFYDEAFRIPAKLIEMQTKYDSISRYIYSGADTSSILDFQLIMLQAK
HHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MNGVLGRTQDQANQLHAIADQLVVATEQTYVSLDQEKSQLEQLSGAMEEMSSTITEVAQN
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
THLTSTSINTAYDLCLKSSANMKANTQKVEQLAKSVADAANNAHQLNKEAEQVANAMGEI
CCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQLSTNSISKSVDKMFTML
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAWAKEMEQSRQHAERCASDIQLSADNVNTLYQEVSDIHTFAQQNAVAADQQRQVVNEIA
HHHHHHHHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SNIHSITHSSAENLAATHLIGDAAHLLKHNAEKALGLRRTFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCC
>Mature Secondary Structure 
SQSNASANRTLNAQRSDQEIRLTPQDELISTTDTRGVITYVNARFAEVSGYSAQELVGS
CCCCCCCCCCCCCCCCCCCEEECCHHHHHCCCCCCCEEEEECHHHHHCCCCCHHHHHHH
AHNMVRHPDMPSAAFKEMWGKLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIVGY
HHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHCCCCEEEE
QSVRIQPQAAYVSKANEIYQRLKLDKSISKPLSLMQKRILSAVVASTGLLIAGYFWGWGV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IIAGAVLMSINLAIFYDEAFRIPAKLIEMQTKYDSISRYIYSGADTSSILDFQLIMLQAK
HHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MNGVLGRTQDQANQLHAIADQLVVATEQTYVSLDQEKSQLEQLSGAMEEMSSTITEVAQN
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
THLTSTSINTAYDLCLKSSANMKANTQKVEQLAKSVADAANNAHQLNKEAEQVANAMGEI
CCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQLSTNSISKSVDKMFTML
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAWAKEMEQSRQHAERCASDIQLSADNVNTLYQEVSDIHTFAQQNAVAADQQRQVVNEIA
HHHHHHHHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SNIHSITHSSAENLAATHLIGDAAHLLKHNAEKALGLRRTFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]