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The map label for this gene is 126175160

Identifier: 126175160

GI number: 126175160

Start: 3470223

End: 3471083

Strand: Direct

Name: 126175160

Synonym: Sbal_2958

Alternate gene names: NA

Gene position: 3470223-3471083 (Clockwise)

Preceding gene: 126175159

Following gene: 126175166

Centisome position: 67.68

GC content: 41.93

Gene sequence:

>861_bases
ATGACTACACATTCACCTATTTTTATCGCTGAAGTCTCCAGCAACCATCATAGAGACTTACAGCGTTGTATTGAGTTTAT
CAAAACTGCTGCAGACATTGGTTGCGATGCCGTAAAGTTTCAGCTTTTCCAAATAGAGCAACTTTTCGCTCCCGAGATTC
TGGCTAAAAGTGAAACGCATCGAAAGCGCAAAGATTGGGAGCTCCCAGTCAGTTTTTTGCCTGAATTAAAACAAAGTTGT
GATGAATATGGCATTCAGTTTTCTTGCACGCCATTCTACTTAGATGCAGTTGCAGAACTGGCTCCATATGTCGATTTTTA
TAAGATTGCCTCCTACGAATTGTTATGGACGGATCTACTAGTAGCCTGTGCAAAAACGGGATTACCTGTAGTTCTTTCAA
CTGGCATGGCTACTTTAGAAGAGATAGATCAAGCGATACTCACGCTAAAAGAAAATGGTGCGAAAGACATCACCTTGCTC
CATTGCGTATCGGCATACCCAACTCCTGAGAATGAATGCAATCTTGCGGTATTAGAAAGCTTTAGAAATCGCTATAAAGT
TAACGTTGGCTGGTCTGATCATACTGTTTCTAGTGCGGTACTTAACCGAGCTGTACACAAATGGCAAGCCGATGTCATAG
AGTTTCATTTAGATTTAGATGAAAAAGGCGATGAATATGCTTCAGGACATTGTTGGCTGCCACAACAGATTGCACCCGTA
ATCCAAGGTATAAAATTAGCCAATGTGATTGATGGCAACCCAGAAAAACAATTTGTTGCGAGTGAAGCCTCAGATAGAGA
ATGGCGAGCGGATCCCCTTGATGGATTACGTCCACTCAAACACATCAGACCGCATTTTTAG

Upstream 100 bases:

>100_bases
ATGAACTAATAGAACTAGTCTGATAAAGCAGAGTACCAGGGCATCAAGCTTCCCAGAGACTTGCCGTTAATAGACTATAC
CGAGCCATTTGCGAGTAACT

Downstream 100 bases:

>100_bases
CCAATAATTCATAACTAAACACCGAGTACTATACAAGGTGTTTAGTTATAGGTTTAGCTAATTTCAAACACAATAGTCTC
GTAAACCCAAGATACTCGCT

Product: N-acetylneuraminic acid synthase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MTTHSPIFIAEVSSNHHRDLQRCIEFIKTAADIGCDAVKFQLFQIEQLFAPEILAKSETHRKRKDWELPVSFLPELKQSC
DEYGIQFSCTPFYLDAVAELAPYVDFYKIASYELLWTDLLVACAKTGLPVVLSTGMATLEEIDQAILTLKENGAKDITLL
HCVSAYPTPENECNLAVLESFRNRYKVNVGWSDHTVSSAVLNRAVHKWQADVIEFHLDLDEKGDEYASGHCWLPQQIAPV
IQGIKLANVIDGNPEKQFVASEASDREWRADPLDGLRPLKHIRPHF

Sequences:

>Translated_286_residues
MTTHSPIFIAEVSSNHHRDLQRCIEFIKTAADIGCDAVKFQLFQIEQLFAPEILAKSETHRKRKDWELPVSFLPELKQSC
DEYGIQFSCTPFYLDAVAELAPYVDFYKIASYELLWTDLLVACAKTGLPVVLSTGMATLEEIDQAILTLKENGAKDITLL
HCVSAYPTPENECNLAVLESFRNRYKVNVGWSDHTVSSAVLNRAVHKWQADVIEFHLDLDEKGDEYASGHCWLPQQIAPV
IQGIKLANVIDGNPEKQFVASEASDREWRADPLDGLRPLKHIRPHF
>Mature_285_residues
TTHSPIFIAEVSSNHHRDLQRCIEFIKTAADIGCDAVKFQLFQIEQLFAPEILAKSETHRKRKDWELPVSFLPELKQSCD
EYGIQFSCTPFYLDAVAELAPYVDFYKIASYELLWTDLLVACAKTGLPVVLSTGMATLEEIDQAILTLKENGAKDITLLH
CVSAYPTPENECNLAVLESFRNRYKVNVGWSDHTVSSAVLNRAVHKWQADVIEFHLDLDEKGDEYASGHCWLPQQIAPVI
QGIKLANVIDGNPEKQFVASEASDREWRADPLDGLRPLKHIRPHF

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=277, Percent_Identity=27.4368231046931, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21357081, Length=283, Percent_Identity=28.6219081272085, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 32353; Mature: 32222

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHSPIFIAEVSSNHHRDLQRCIEFIKTAADIGCDAVKFQLFQIEQLFAPEILAKSETH
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHH
RKRKDWELPVSFLPELKQSCDEYGIQFSCTPFYLDAVAELAPYVDFYKIASYELLWTDLL
HHCCCCCCCHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VACAKTGLPVVLSTGMATLEEIDQAILTLKENGAKDITLLHCVSAYPTPENECNLAVLES
HHHHHCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCHHEEEHHCCCCCCCCCCHHHHHH
FRNRYKVNVGWSDHTVSSAVLNRAVHKWQADVIEFHLDLDEKGDEYASGHCWLPQQIAPV
HHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHH
IQGIKLANVIDGNPEKQFVASEASDREWRADPLDGLRPLKHIRPHF
HHCCHHHHHCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTHSPIFIAEVSSNHHRDLQRCIEFIKTAADIGCDAVKFQLFQIEQLFAPEILAKSETH
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHH
RKRKDWELPVSFLPELKQSCDEYGIQFSCTPFYLDAVAELAPYVDFYKIASYELLWTDLL
HHCCCCCCCHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VACAKTGLPVVLSTGMATLEEIDQAILTLKENGAKDITLLHCVSAYPTPENECNLAVLES
HHHHHCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCHHEEEHHCCCCCCCCCCHHHHHH
FRNRYKVNVGWSDHTVSSAVLNRAVHKWQADVIEFHLDLDEKGDEYASGHCWLPQQIAPV
HHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHH
IQGIKLANVIDGNPEKQFVASEASDREWRADPLDGLRPLKHIRPHF
HHCCHHHHHCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]