Click here to switch to the map view.

The map label for this gene is etfA [H]

Identifier: 126175051

GI number: 126175051

Start: 3353929

End: 3354855

Strand: Reverse

Name: etfA [H]

Synonym: Sbal_2846

Alternate gene names: 126175051

Gene position: 3354855-3353929 (Counterclockwise)

Preceding gene: 126175052

Following gene: 126175050

Centisome position: 65.43

GC content: 49.3

Gene sequence:

>927_bases
ATGGCCATTTTAGTATTAGCTGAACATGATAATGCCGCACTGAAACTTGATACCGCAAAAATCGTCACTGCCGCTCGCGC
CATTGGCGATGAAGTGCATGTACTGGTTGCGGGTCACCAATGTGGCGCGGTTGTCCAAGCTGCAAAAGCACTTCAAGGCG
TTAGCCAAGTGCTCGTTGCGGATGCTAGCGTTTATGAAGCGCATTTAGCTGAAAATTTTGCCAAATTGTTGGTGGACTTA
GCGCCAAACTATGGCCACATTCTGGCTTCTGCTTCGAGCTTAGGTAAGGACACGCTCCCGCGTGTGGCAGCATTATTAGA
TGTTGCGCAAATCTCTGAAGTCATTACCGTCGTCAGTGCGGACACTTTTGTGCGCCCTGTGTATGCGGGTAATGCCTTAG
CGACAGTGCAAAGCCATGATGTCATCAAAGTGATGACAGTACGCGCCAGTGCCTTTGATGCTGCGCCAGAAGGTAACAGC
GCGGCTGTGACGATACTCGATAAAGTGTTTGAAGCGAGAACTCAGTTTGTTTCTCAATCCTTGACGGTATCAGCCCGTCC
AGAATTAGGTAATGCTGGCATTATCGTTTCTGGCGGCCGTGGTATGGGCAGTGGTGAAAACTTCGGCATGTTAGAACAAC
TTGCTGACAAGCTCGGTGCTGCGGTTGGCGCATCACGCGCGGCAGTTGACGCTGGCTTTGTGCCTAACGATTTACAAGTC
GGTCAAACCGGTAAAATCGTTGCACCTAACTTGTATATTGCCGTGGGGATTTCTGGCGCGATTCAGCATTTAGCGGGCAT
GAAAGACGCAAAAGTTATCGTTGCTATCAATAAAGATCCTGAAGCACCAATTTTCCAAGTTGCCGATTATGGCTTAGTTG
CCGATTTATTTGAGGCGGTTCCTGAGCTGATCACAAGTCTCGGTTGA

Upstream 100 bases:

>100_bases
TGTGAAGGTCACTCCGCCAGCAGAACGTAAAGCAGGCATCATGGTAGCGTCGGTAGCTGAGCTAGTTGAAAAGTTAAAAA
ATGAAGCGAAGGTGATCTAA

Downstream 100 bases:

>100_bases
TTTAAACTGTGATCTAGGTCACATTAAGTGGCTTTGCGCTAGCATCTGCTAAGCCGCTTATGTTTTTATGTGCCTCACGC
CCGCGTACGGGCGTTCTTAG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAILVLAEHDNAALKLDTAKIVTAARAIGDEVHVLVAGHQCGAVVQAAKALQGVSQVLVADASVYEAHLAENFAKLLVDL
APNYGHILASASSLGKDTLPRVAALLDVAQISEVITVVSADTFVRPVYAGNALATVQSHDVIKVMTVRASAFDAAPEGNS
AAVTILDKVFEARTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLVADLFEAVPELITSLG

Sequences:

>Translated_308_residues
MAILVLAEHDNAALKLDTAKIVTAARAIGDEVHVLVAGHQCGAVVQAAKALQGVSQVLVADASVYEAHLAENFAKLLVDL
APNYGHILASASSLGKDTLPRVAALLDVAQISEVITVVSADTFVRPVYAGNALATVQSHDVIKVMTVRASAFDAAPEGNS
AAVTILDKVFEARTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLVADLFEAVPELITSLG
>Mature_307_residues
AILVLAEHDNAALKLDTAKIVTAARAIGDEVHVLVAGHQCGAVVQAAKALQGVSQVLVADASVYEAHLAENFAKLLVDLA
PNYGHILASASSLGKDTLPRVAALLDVAQISEVITVVSADTFVRPVYAGNALATVQSHDVIKVMTVRASAFDAAPEGNSA
AVTILDKVFEARTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQVG
QTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLVADLFEAVPELITSLG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=58.1699346405229, Blast_Score=333, Evalue=9e-92,
Organism=Homo sapiens, GI189181759, Length=265, Percent_Identity=60.377358490566, Blast_Score=302, Evalue=2e-82,
Organism=Escherichia coli, GI1786226, Length=308, Percent_Identity=30.8441558441558, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787990, Length=298, Percent_Identity=30.5369127516779, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87082157, Length=224, Percent_Identity=31.6964285714286, Blast_Score=78, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=310, Percent_Identity=53.8709677419355, Blast_Score=308, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6325261, Length=293, Percent_Identity=45.3924914675768, Blast_Score=250, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=59.4855305466238, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=59.4855305466238, Blast_Score=343, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31594; Mature: 31462

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVLAEHDNAALKLDTAKIVTAARAIGDEVHVLVAGHQCGAVVQAAKALQGVSQVLVA
CEEEEEEECCCCEEEECHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
DASVYEAHLAENFAKLLVDLAPNYGHILASASSLGKDTLPRVAALLDVAQISEVITVVSA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DTFVRPVYAGNALATVQSHDVIKVMTVRASAFDAAPEGNSAAVTILDKVFEARTQFVSQS
HHHCCEEECCCEEEEECCCCEEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
LTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
CEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEE
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLVADLFEAV
CCCCCEECCCEEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHCCHHHHHHHHHH
PELITSLG
HHHHHHCC
>Mature Secondary Structure 
AILVLAEHDNAALKLDTAKIVTAARAIGDEVHVLVAGHQCGAVVQAAKALQGVSQVLVA
EEEEEEECCCCEEEECHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
DASVYEAHLAENFAKLLVDLAPNYGHILASASSLGKDTLPRVAALLDVAQISEVITVVSA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DTFVRPVYAGNALATVQSHDVIKVMTVRASAFDAAPEGNSAAVTILDKVFEARTQFVSQS
HHHCCEEECCCEEEEECCCCEEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
LTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
CEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEE
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLVADLFEAV
CCCCCEECCCEEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHCCHHHHHHHHHH
PELITSLG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]