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The map label for this gene is mmgC [H]

Identifier: 126175033

GI number: 126175033

Start: 3328032

End: 3329201

Strand: Direct

Name: mmgC [H]

Synonym: Sbal_2828

Alternate gene names: 126175033

Gene position: 3328032-3329201 (Clockwise)

Preceding gene: 126175032

Following gene: 126175034

Centisome position: 64.91

GC content: 52.14

Gene sequence:

>1170_bases
ATGAACTCTCTCTACACAAGTCTGAATTTTGGCCTAGGCGAAGACGTCGACATGCTGCGCGATGCGGTGCAAGATTTTGC
CACTCACGAAATCGCCCCGATTGCCGCGAAAGTGGATCACGACAACGCCTTCCCCAATGAACTTTGGCCTGTGCTGGGGA
GTATGGGACTGCTCGGCGTAACCGTAGCTGAAGAGTACGGCGGCGCGAACATGGGCTACCTTGCCCACGTCGTGGCGATG
GAAGAAATCTCCCGAGCATCGGCCTCTATCGGCCTAAGCTACGGCGCCCACTCAAACCTGTGTGTGAATCAAATCAACCG
TAACGGTAATGCCGCGCAAAAAGCCAAGTATCTGCCAAAACTGGTGAGCGGTGAACATATCGGCGCACTCGCCATGAGTG
AGCCAAACGCGGGTTCTGACGTAGTTTCGATGAAACTACACGCCCGTAAAGAAGGCGACCGTTTCATCTTAAACGGTAAC
AAGATGTGGATCACCAACGGCCCCGATGCACACACCTATGTGATTTACGCTAAAACCGACTTAACCAAAGGCGCACACGG
TATTACCGCCTTTATCGTTGAGCGTGATTCGAAAGGTTTCAGCCAAGCACAAAAACTCGACAAACTCGGCATGCGCGGCT
CTAACACCTGCGAATTAGTGTTTGAAGATGTGGAAGTGCCAGAAGAAAACATTTTAGGTGGCCTCAACAACGGCGTTAAA
GTGCTGATGAGCGGCCTAGATTACGAGCGCGTCGTGCTATCTGGCGGCCCGCTGGGGATCATGAACGCTTGTATGGATAT
CGTTGTACCTTACATCCACGAGCGTGAGCAATTTGGTAAATCGATTGGTGAATTCCAACTGGTACAGGGCAAATTAGCCG
ACATGTACACCGGCATGAATGCCGCCAAATCCTACGTATATGCCGTGGCAAAATCCTGCGATCGCGGTGAAACCACCCGT
AAAGATGCCGCGGGCGCCATTCTGTATAGTGCAGAACTCGCGACTAAAATGGCACTGGATGCAATCCAACTGCTCGGCGG
CAATGGTTATGTTAACGAATACGCCACCGGCCGCTTACTGCGTGATGCCAAGCTGTATGAAATCGGCGCAGGCACCTCAG
AAATTCGCCGCATGCTGATTGGCCGCGAACTGTTCAATGAGTCGAAATAA

Upstream 100 bases:

>100_bases
AAGATTTAAAAGACTCAAGCACCTAAAAATCATAAAAACTATAAATTTAAACATCAGAGTTTAACCATCTGAAATTAGAA
CATCTGAAAGGACACAAGCA

Downstream 100 bases:

>100_bases
CGCGAGTTCCAATAATCTCTCACAAGTGAATGGGTAGCACCTCACTGTAACTTACAGTTTGCGCCACCCATTCGAGCAAG
GTGATACCGAGTTTCCGCTT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 3-methylbut-2-enoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNSLYTSLNFGLGEDVDMLRDAVQDFATHEIAPIAAKVDHDNAFPNELWPVLGSMGLLGVTVAEEYGGANMGYLAHVVAM
EEISRASASIGLSYGAHSNLCVNQINRNGNAAQKAKYLPKLVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRFILNGN
KMWITNGPDAHTYVIYAKTDLTKGAHGITAFIVERDSKGFSQAQKLDKLGMRGSNTCELVFEDVEVPEENILGGLNNGVK
VLMSGLDYERVVLSGGPLGIMNACMDIVVPYIHEREQFGKSIGEFQLVQGKLADMYTGMNAAKSYVYAVAKSCDRGETTR
KDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFNESK

Sequences:

>Translated_389_residues
MNSLYTSLNFGLGEDVDMLRDAVQDFATHEIAPIAAKVDHDNAFPNELWPVLGSMGLLGVTVAEEYGGANMGYLAHVVAM
EEISRASASIGLSYGAHSNLCVNQINRNGNAAQKAKYLPKLVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRFILNGN
KMWITNGPDAHTYVIYAKTDLTKGAHGITAFIVERDSKGFSQAQKLDKLGMRGSNTCELVFEDVEVPEENILGGLNNGVK
VLMSGLDYERVVLSGGPLGIMNACMDIVVPYIHEREQFGKSIGEFQLVQGKLADMYTGMNAAKSYVYAVAKSCDRGETTR
KDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFNESK
>Mature_389_residues
MNSLYTSLNFGLGEDVDMLRDAVQDFATHEIAPIAAKVDHDNAFPNELWPVLGSMGLLGVTVAEEYGGANMGYLAHVVAM
EEISRASASIGLSYGAHSNLCVNQINRNGNAAQKAKYLPKLVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRFILNGN
KMWITNGPDAHTYVIYAKTDLTKGAHGITAFIVERDSKGFSQAQKLDKLGMRGSNTCELVFEDVEVPEENILGGLNNGVK
VLMSGLDYERVVLSGGPLGIMNACMDIVVPYIHEREQFGKSIGEFQLVQGKLADMYTGMNAAKSYVYAVAKSCDRGETTR
KDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFNESK

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=64.0957446808511, Blast_Score=506, Evalue=1e-143,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=67.2566371681416, Blast_Score=485, Evalue=1e-137,
Organism=Homo sapiens, GI4557233, Length=386, Percent_Identity=40.1554404145078, Blast_Score=281, Evalue=5e-76,
Organism=Homo sapiens, GI4501859, Length=367, Percent_Identity=36.2397820163488, Blast_Score=259, Evalue=2e-69,
Organism=Homo sapiens, GI21361497, Length=380, Percent_Identity=37.6315789473684, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI4557231, Length=385, Percent_Identity=35.0649350649351, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI187960098, Length=385, Percent_Identity=35.0649350649351, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=33.4224598930481, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI76496475, Length=353, Percent_Identity=34.8441926345609, Blast_Score=207, Evalue=9e-54,
Organism=Homo sapiens, GI4557235, Length=353, Percent_Identity=34.8441926345609, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI7656849, Length=383, Percent_Identity=30.5483028720627, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI4503943, Length=375, Percent_Identity=28.8, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI7669494, Length=371, Percent_Identity=29.3800539083558, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI48976061, Length=284, Percent_Identity=25.3521126760563, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI211971008, Length=284, Percent_Identity=25.3521126760563, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1786223, Length=383, Percent_Identity=27.4151436031332, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI87081958, Length=384, Percent_Identity=29.6875, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI87082384, Length=259, Percent_Identity=25.8687258687259, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081702, Length=338, Percent_Identity=25.1479289940828, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=380, Percent_Identity=62.8947368421053, Blast_Score=508, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17506239, Length=378, Percent_Identity=33.8624338624339, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=36.4829396325459, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=33.4231805929919, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=34.8167539267016, Blast_Score=231, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI17570075, Length=386, Percent_Identity=32.1243523316062, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=38.4057971014493, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=30.3430079155673, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71985184, Length=353, Percent_Identity=34.2776203966006, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17505929, Length=354, Percent_Identity=32.7683615819209, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=37.2294372294372, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=30.5177111716621, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=33.9416058394161, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=29.3333333333333, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI71985192, Length=313, Percent_Identity=33.2268370607029, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17531909, Length=246, Percent_Identity=31.7073170731707, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21355753, Length=384, Percent_Identity=60.9375, Blast_Score=483, Evalue=1e-137,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=40.6914893617021, Blast_Score=292, Evalue=3e-79,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=37.5, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=34.5646437994723, Blast_Score=251, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24660351, Length=387, Percent_Identity=35.9173126614987, Blast_Score=248, Evalue=4e-66,
Organism=Drosophila melanogaster, GI281363737, Length=359, Percent_Identity=32.5905292479109, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI19920834, Length=389, Percent_Identity=28.7917737789203, Blast_Score=154, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.10

Molecular weight: Translated: 42032; Mature: 42032

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLYTSLNFGLGEDVDMLRDAVQDFATHEIAPIAAKVDHDNAFPNELWPVLGSMGLLGV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCHHEE
TVAEEYGGANMGYLAHVVAMEEISRASASIGLSYGAHSNLCVNQINRNGNAAQKAKYLPK
EEHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHCCCCCHHHHHHHHHH
LVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRFILNGNKMWITNGPDAHTYVIYAKTD
HHCCCCCCEEEECCCCCCCCEEEEEEEECCCCCEEEEECCEEEEECCCCCEEEEEEEECC
LTKGAHGITAFIVERDSKGFSQAQKLDKLGMRGSNTCELVFEDVEVPEENILGGLNNGVK
CCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCCCCHH
VLMSGLDYERVVLSGGPLGIMNACMDIVVPYIHEREQFGKSIGEFQLVQGKLADMYTGMN
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHH
AAKSYVYAVAKSCDRGETTRKDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLL
HHHHHHHHHHHHCCCCCCCHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHH
RDAKLYEIGAGTSEIRRMLIGRELFNESK
HCCEEEEECCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNSLYTSLNFGLGEDVDMLRDAVQDFATHEIAPIAAKVDHDNAFPNELWPVLGSMGLLGV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCHHEE
TVAEEYGGANMGYLAHVVAMEEISRASASIGLSYGAHSNLCVNQINRNGNAAQKAKYLPK
EEHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHCCCCCHHHHHHHHHH
LVSGEHIGALAMSEPNAGSDVVSMKLHARKEGDRFILNGNKMWITNGPDAHTYVIYAKTD
HHCCCCCCEEEECCCCCCCCEEEEEEEECCCCCEEEEECCEEEEECCCCCEEEEEEEECC
LTKGAHGITAFIVERDSKGFSQAQKLDKLGMRGSNTCELVFEDVEVPEENILGGLNNGVK
CCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCCCCHH
VLMSGLDYERVVLSGGPLGIMNACMDIVVPYIHEREQFGKSIGEFQLVQGKLADMYTGMN
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHH
AAKSYVYAVAKSCDRGETTRKDAAGAILYSAELATKMALDAIQLLGGNGYVNEYATGRLL
HHHHHHHHHHHHCCCCCCCHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHH
RDAKLYEIGAGTSEIRRMLIGRELFNESK
HCCEEEEECCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-methylbutanoyl-CoA; acceptor

Specific reaction: 3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]