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The map label for this gene is pip [H]

Identifier: 126174942

GI number: 126174942

Start: 3208301

End: 3209590

Strand: Direct

Name: pip [H]

Synonym: Sbal_2735

Alternate gene names: 126174942

Gene position: 3208301-3209590 (Clockwise)

Preceding gene: 126174931

Following gene: 126174944

Centisome position: 62.57

GC content: 46.9

Gene sequence:

>1290_bases
ATGAAACCCGATATTATTCTCGCCGGAGTGCTGGCGAAGAAACATACTTTTACCTTGCCCCTCAACTATCAAAATCCGAT
TGCAGAGCAAATCCAAGTGTTTGCCAGAGAACTCTGTAGCCCAGAAAACAAAGATAAAAAGCTACCTTATATCGTATTTT
TCCAAGGCGGTCCCGGATTTGCGGCCATGCGCCCCGCCAGCAACAGCGGCTGGATCCGCCGTGCATTAAAAGAATATCGG
GTGTTATTACTCGATCAGCGCGGCACAGGCTTATCAACACCGATTAATTACCAAAGCCTGCAACACTTAGAGCCAACAGC
TCAAGCGGATTACCTAAGCCATTTCAGGGCTGACAATATTATTCGTGATGCCGAGACGATTCGTGCCCAGCTTTGCCCCG
CCGATAAATGGGCGATTCTTGGCCAAAGCTTCGGGGGATTTTGCGTATTACATTATTTAAGCGCCGCCCCTCAAGGTGTC
AGCGAAGCCTATATTACAGGTGGCATACCGTCATTAACCCGCAGCGCCGATGACGTCTACCTTGCAACTTATCAACGCGT
GCTGGCGAAGAATAAACAATTTTTCCAACGCTTTCACGATGCCCAACATTTAGTTACTCGCTTAGCAAAACACTTGCTTG
AAAATGAAGTGTATTTAGCAACGGGAGAACGCCTCACGGTTGAAATGTTGCAGCTGCTGGGTATTAATATCGGAATGGAG
CAAGGGCCTGAATCGGTTTACTATTTACTTGAGCAAGCCTTAATCAACACGGCTTCTGGGACAGTCGTGAACCCCTTATT
TTTAAATCATTTCGGTCAAATGCTCGACTACAACACTAACCCGATTTTTGCCCTGCTGCATGAGGCCATTTACTGCCAGC
ACTCAGCTTCACAATGGGCGGCACACAGAGTAAGACAACAATTCCCCGCCTTTAATTATCAGCAAGGTAAACCATTTTTA
TTCACCGGCGAGATGATTTACCCTTGGATGTTTGACCAATTCAGTCATTTAGTACCGCTTAAAGCCGCGGCAGAAATCCT
TGCCCATAAATCAGATTGGCCTGCACTGTATAATCTTGAACAACTGGCGCAAAACCGCGTCCCCGTTGCCACAGCGATTT
ACAGTGAAGATATGTTTGTCGAGATGCAATACAGCCTAGAAACCGCGCAACAGGTCGGCAGGCTAAAGTATTGGTTAACC
TCAGAATATGAACACAACGGCATTCGCATGGATGGCGAGCACATACTGGATAAGCTCATCAGCTTAAACCGAGGCGACAC
CTTAAGATAA

Upstream 100 bases:

>100_bases
ATACGAGTTTCAACTAGCCTAGATTGCTGCATCTTCAGGTTATTTGGGTATACAATCTGCCAATCACAATAACATGATCC
TCTGCCATTAAGGTTGTTTG

Downstream 100 bases:

>100_bases
AGGTTAATTTTAAGGGCTAATTAAGTTAACGCTGACATTATAAACCTGCTCCTCATCTATTGAGTGATTTTGGCAAGTTT
CAACGACCTATTTCCGTATG

Product: alpha/beta hydrolase fold domain-containing protein

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKPDIILAGVLAKKHTFTLPLNYQNPIAEQIQVFARELCSPENKDKKLPYIVFFQGGPGFAAMRPASNSGWIRRALKEYR
VLLLDQRGTGLSTPINYQSLQHLEPTAQADYLSHFRADNIIRDAETIRAQLCPADKWAILGQSFGGFCVLHYLSAAPQGV
SEAYITGGIPSLTRSADDVYLATYQRVLAKNKQFFQRFHDAQHLVTRLAKHLLENEVYLATGERLTVEMLQLLGINIGME
QGPESVYYLLEQALINTASGTVVNPLFLNHFGQMLDYNTNPIFALLHEAIYCQHSASQWAAHRVRQQFPAFNYQQGKPFL
FTGEMIYPWMFDQFSHLVPLKAAAEILAHKSDWPALYNLEQLAQNRVPVATAIYSEDMFVEMQYSLETAQQVGRLKYWLT
SEYEHNGIRMDGEHILDKLISLNRGDTLR

Sequences:

>Translated_429_residues
MKPDIILAGVLAKKHTFTLPLNYQNPIAEQIQVFARELCSPENKDKKLPYIVFFQGGPGFAAMRPASNSGWIRRALKEYR
VLLLDQRGTGLSTPINYQSLQHLEPTAQADYLSHFRADNIIRDAETIRAQLCPADKWAILGQSFGGFCVLHYLSAAPQGV
SEAYITGGIPSLTRSADDVYLATYQRVLAKNKQFFQRFHDAQHLVTRLAKHLLENEVYLATGERLTVEMLQLLGINIGME
QGPESVYYLLEQALINTASGTVVNPLFLNHFGQMLDYNTNPIFALLHEAIYCQHSASQWAAHRVRQQFPAFNYQQGKPFL
FTGEMIYPWMFDQFSHLVPLKAAAEILAHKSDWPALYNLEQLAQNRVPVATAIYSEDMFVEMQYSLETAQQVGRLKYWLT
SEYEHNGIRMDGEHILDKLISLNRGDTLR
>Mature_429_residues
MKPDIILAGVLAKKHTFTLPLNYQNPIAEQIQVFARELCSPENKDKKLPYIVFFQGGPGFAAMRPASNSGWIRRALKEYR
VLLLDQRGTGLSTPINYQSLQHLEPTAQADYLSHFRADNIIRDAETIRAQLCPADKWAILGQSFGGFCVLHYLSAAPQGV
SEAYITGGIPSLTRSADDVYLATYQRVLAKNKQFFQRFHDAQHLVTRLAKHLLENEVYLATGERLTVEMLQLLGINIGME
QGPESVYYLLEQALINTASGTVVNPLFLNHFGQMLDYNTNPIFALLHEAIYCQHSASQWAAHRVRQQFPAFNYQQGKPFL
FTGEMIYPWMFDQFSHLVPLKAAAEILAHKSDWPALYNLEQLAQNRVPVATAIYSEDMFVEMQYSLETAQQVGRLKYWLT
SEYEHNGIRMDGEHILDKLISLNRGDTLR

Specific function: Higher activity toward long peptides. Acts on hydroxyproline beta-naphthylamide with almost as high an activity as on proline beta-naphthylamide [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 48774; Mature: 48774

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPDIILAGVLAKKHTFTLPLNYQNPIAEQIQVFARELCSPENKDKKLPYIVFFQGGPGF
CCCCEEEEEEHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCC
AAMRPASNSGWIRRALKEYRVLLLDQRGTGLSTPINYQSLQHLEPTAQADYLSHFRADNI
EEECCCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
IRDAETIRAQLCPADKWAILGQSFGGFCVLHYLSAAPQGVSEAYITGGIPSLTRSADDVY
HHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCHHHCCCCHHH
LATYQRVLAKNKQFFQRFHDAQHLVTRLAKHLLENEVYLATGERLTVEMLQLLGINIGME
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCC
QGPESVYYLLEQALINTASGTVVNPLFLNHFGQMLDYNTNPIFALLHEAIYCQHSASQWA
CCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHH
AHRVRQQFPAFNYQQGKPFLFTGEMIYPWMFDQFSHLVPLKAAAEILAHKSDWPALYNLE
HHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHCHH
QLAQNRVPVATAIYSEDMFVEMQYSLETAQQVGRLKYWLTSEYEHNGIRMDGEHILDKLI
HHHCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHEEEECCCCCCCEEECHHHHHHHHH
SLNRGDTLR
HCCCCCCCC
>Mature Secondary Structure
MKPDIILAGVLAKKHTFTLPLNYQNPIAEQIQVFARELCSPENKDKKLPYIVFFQGGPGF
CCCCEEEEEEHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCC
AAMRPASNSGWIRRALKEYRVLLLDQRGTGLSTPINYQSLQHLEPTAQADYLSHFRADNI
EEECCCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
IRDAETIRAQLCPADKWAILGQSFGGFCVLHYLSAAPQGVSEAYITGGIPSLTRSADDVY
HHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCHHHCCCCHHH
LATYQRVLAKNKQFFQRFHDAQHLVTRLAKHLLENEVYLATGERLTVEMLQLLGINIGME
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCC
QGPESVYYLLEQALINTASGTVVNPLFLNHFGQMLDYNTNPIFALLHEAIYCQHSASQWA
CCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHH
AHRVRQQFPAFNYQQGKPFLFTGEMIYPWMFDQFSHLVPLKAAAEILAHKSDWPALYNLE
HHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHCHH
QLAQNRVPVATAIYSEDMFVEMQYSLETAQQVGRLKYWLTSEYEHNGIRMDGEHILDKLI
HHHCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHEEEECCCCCCCEEECHHHHHHHHH
SLNRGDTLR
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883756 [H]