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The map label for this gene is iorA [H]

Identifier: 126174937

GI number: 126174937

Start: 3202852

End: 3203370

Strand: Reverse

Name: iorA [H]

Synonym: Sbal_2730

Alternate gene names: 126174937

Gene position: 3203370-3202852 (Counterclockwise)

Preceding gene: 126174938

Following gene: 126174936

Centisome position: 62.48

GC content: 51.64

Gene sequence:

>519_bases
ATGGCAGAAGTTTTATCAACCAAAGCAGTCGTCAAGGAAGCGAATACCGCCGCTTCCACCCAGACACTTTCCGCTCAGAC
ACTGACCATCAACGGTAAATCATTTACCTTAGATGCCGATCCTAAAATGCCAATCCTGTGGGCACTACGGGATATTTTAG
GGCTCACGGGCACTAAATATGGCTGCGGTGCAGGGCTATGCGGTGCTTGCACAGTGCATTTAGACGGCCAACCCGTACGC
GCCTGTTTAACCAGTTTGGGGCAGGCACAGGGAAAACGACTGACAACAATTGAAGGGCTAGATAATCAAAAGCTTAAAAA
TGCTTGGGCCGAACATAACGTGCCCCAGTGTGGCTATTGTCAGGCGGGCCAACTGATGTCGGCTGCGGCGTTGGTGGCGC
AGCATCCGAAACCTTCTGAAGAACAAATTAACTCGGCCATGTCGGGTAATCTCTGCCGCTGCGGTACATACCCGCGGATT
AAAGCGGCACTGCAAAACTATGCCAAACAGGAGGGCTAA

Upstream 100 bases:

>100_bases
ACAGCAGGGAGCGTTAGTCGCTATAACACTACCCCGCGCCGCAATTGATATTGATACCCAAGCCGATCTTGCGTCGTGGT
TGGCACTTAAGGAGTGAGTT

Downstream 100 bases:

>100_bases
TATGAGTACTTTTACTGCCGTAGAAAATATCAGCCGCCGCGACGTGTTAAAACTGTTTGGCGCAGTGGGTGGCGGATTAG
CATTAGGAGCGAGTGGATTA

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MAEVLSTKAVVKEANTAASTQTLSAQTLTINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVR
ACLTSLGQAQGKRLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQLMSAAALVAQHPKPSEEQINSAMSGNLCRCGTYPRI
KAALQNYAKQEG

Sequences:

>Translated_172_residues
MAEVLSTKAVVKEANTAASTQTLSAQTLTINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVR
ACLTSLGQAQGKRLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQLMSAAALVAQHPKPSEEQINSAMSGNLCRCGTYPRI
KAALQNYAKQEG
>Mature_171_residues
AEVLSTKAVVKEANTAASTQTLSAQTLTINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVRA
CLTSLGQAQGKRLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQLMSAAALVAQHPKPSEEQINSAMSGNLCRCGTYPRIK
AALQNYAKQEG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=156, Percent_Identity=36.5384615384615, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI71773480, Length=101, Percent_Identity=33.6633663366337, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786480, Length=163, Percent_Identity=39.8773006134969, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=39.0070921985816, Blast_Score=90, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=37.4193548387097, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=165, Percent_Identity=36.3636363636364, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=176, Percent_Identity=34.6590909090909, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17737937, Length=157, Percent_Identity=36.9426751592357, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24647193, Length=163, Percent_Identity=34.9693251533742, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=32.9032258064516, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=33.125, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=33.125, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 18150; Mature: 18019

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVLSTKAVVKEANTAASTQTLSAQTLTINGKSFTLDADPKMPILWALRDILGLTGTKY
CCCHHHHHHHHHHCCCHHCCEECCEEEEEECCCEEEECCCCCCHHHHHHHHHHHCCCCCC
GCGAGLCGACTVHLDGQPVRACLTSLGQAQGKRLTTIEGLDNQKLKNAWAEHNVPQCGYC
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCC
QAGQLMSAAALVAQHPKPSEEQINSAMSGNLCRCGTYPRIKAALQNYAKQEG
CHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEVLSTKAVVKEANTAASTQTLSAQTLTINGKSFTLDADPKMPILWALRDILGLTGTKY
CCHHHHHHHHHHCCCHHCCEECCEEEEEECCCEEEECCCCCCHHHHHHHHHHHCCCCCC
GCGAGLCGACTVHLDGQPVRACLTSLGQAQGKRLTTIEGLDNQKLKNAWAEHNVPQCGYC
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCC
QAGQLMSAAALVAQHPKPSEEQINSAMSGNLCRCGTYPRIKAALQNYAKQEG
CHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]