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The map label for this gene is btuB [H]

Identifier: 126174878

GI number: 126174878

Start: 3127831

End: 3130233

Strand: Direct

Name: btuB [H]

Synonym: Sbal_2669

Alternate gene names: 126174878

Gene position: 3127831-3130233 (Clockwise)

Preceding gene: 126174875

Following gene: 126174880

Centisome position: 61.0

GC content: 40.57

Gene sequence:

>2403_bases
ATGTCCGTTGCTGACGTACTGCGTAGAAGTAACTTAAACAGCTTCGGGTCTACTTCAGAACGTTCAGGTAGTAGTGCTCA
GTCACAAGCGACAATTAACCTCCGTGGTGCGGGTTCAGATCGTACTTTAGTACTATTAAATGGCAAGCGTATGCCAGGCT
CACCAACATTAGGTGGAACCGCTGTCAATCTTAATACTATCCCAACTGCTGCAATTGAAAGAATTGAGGTATTAACAGAT
GGTGCTTCCGCAGTATATGGTTCAGATGCCGTTGCAGGTGTAGTCAATATTATTCTTAAAAAAGGATTTGAAGGCCTTGA
AGTTTCAGCGACCAGCTCACAACCCGTTCAAGATGGTGGTGAAGAATGGAAGACACAAATTGTGGGTGGCGCTGTTGGTG
AAAAAGGCAGTGTCACTTTCTCTTTTGAACACTTAAACCGCGAAATCATTTATCAACGTGATCGCTGGTTTTCAAGTTCC
TCAAATGTCCTAGCACCAAAATTTGACGATACCACTGGCGTTTCAACTTACGCTCGTAATTTCCTTGATGGAAAAACAGG
CCAATTCAAGCCCATGACGGCTTGTGATAATCCTAAGATGGTGGGTGGTGGGCATATCTATGATGCTGGCGATGGTGACT
ATGTTTGTGGTTACGATTTTACTGCAGAAGCTGCTGATCATGCTGCACGTTCTTACACTGCTGGCTATGTAAATGCAGAA
TATGAACTTTCTGATGAAATCGTTTTTCAAGGCTTAGGTCTATTCTCTCGCAATGAGACTTTTGGTCGCTATGCTCCAGC
AGCAGGCTGGTTTAATGTCGCCCCTGGTCAAGTTGAAGTAAAAAATTACGATGCAAATGGCAAATACACTGGTAACAGTT
TGAACGAAAATGCTGGGCGAGCTTATTATCGCTTCACAGATGTTGGTACTCGTGATGCGAAAACTGTCGATTACAGCACT
GACATTCAATTGGGTTTAGTTGGTACGCATGACAGCTTCGGTTGGGATTTTACATACCATTATAATTTAGCTGAAAATAG
TAACTATGGTACTGGATATGTACACAGACCTACAGTTGAAAGATATGTTAAAGATGGCATTTTCAACTTTGGTCCTGAAG
GTAATAGTGCATCTGTTATAGCCGACATGGCTCACAAAACCCTTAAGCAAGATATAATGGAGTTTCAAAGTGTCAATGCT
GGTGTAAACTTTGAAGCCATTGAATTACCCGCAGGTAACATTGGTTGGTACATAGGAACTGAAGCTCTCCAATACAAGTA
TGAAGCTAACGTTGATGCGCAAACCGCTGCTGGTGACGTGATTGGTTCATCTGGTAATGGCGCTTCAGGTGATCGTGATG
TCTATGCACTGTTCGCTGAATCCATTATCCCTGTAACCGAAGATTTAGAATTAAACTTAGCTTATCGCTACGATAACTAC
TCTGACTTTGGTTCTGCTACAACACCAAAAGTCGCCCTAAGATATCAACTCTTAGATGACGTTGTATTCAGAGCATCATG
GGGTCAAGGTTTCCGCGCACCATCATTGTCAGATCTAATTGCTTCGGATTCGTTTAGCGCAGATACGGCAACTGATTACC
ATTACTGCGATGTTCTAGGCACTAATGTTGCTGACTGTAAAGCTAAGCAATATGATGTGACACGCACTGCAAATAAAGAG
TTGCAACCAGAAACATCAAACTTCTACAACTTAGGACTTGTATGGGACATCACTGATAAACTAAGTACTAAAATTGAGTA
TTACAACTTAGATATCAAAGATGTTATTACTTTTGTCTCTTTAGACTCACTACTGAAAGAAGAACAGAAAGTTGGATACG
GTAACTTAAGCCGCGGTGAAATTAAACGTGTAGGAGATAATCCGAATGGAAAATTGTTGTCAGCAACAACACCTAAAGCA
AATGGCAACGGTTTCGATACTTCTGGTATTGACTTCAATCTAACATATAGTGGATTTGAAACAACTATTGGTGACTTTAG
CAGTTCGTACGATCTAAGCTATATTCTTTCTTATAATGAAGAGGAATATTTTGATGGGCCTGTAAATGATAAAATTGGCC
GTAATGGTATGCCTGAATTCAGATTCACTTGGGTTATCGACTGGAGCTATGGCGATCACTCAGCATCTATATTGACACAA
TATATTGATGGCCAATCAGAAAAAACAGATCCAAATACATACGCCCAAGTTGGAAGCTTGTCTTCGCAAACAACATTCGA
TATTAGCTATGGCTATGCTACACCGTGGGAAGGAAAAATTAGTTTAGGTATTCGTAACTTAACTAATGAAGATCCTGTTT
TAGATTCTGATCTTAAATATGATGCTTCTCTATACAACTTATATGGCCGTACATTTACGGCAACATATACACAGAAATTC
TAA

Upstream 100 bases:

>100_bases
ATCAACCGGCCATTCTAATTGTCGCTGAACCGGTCAGGGTAATTGTCGCGCAATACACGTTACAACTATCAGTGCCTCCG
ATATAGAGAAAACAGGTGAA

Downstream 100 bases:

>100_bases
TATCTCATTTCTCAATTAGAACCTAATCAAAAAACGGCATCTTCGGATGCTGTTTTTATTTGCTTCTTTTACGCAGCCCA
GTAAATAAGCATAAAAAATG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 800; Mature: 799

Protein sequence:

>800_residues
MSVADVLRRSNLNSFGSTSERSGSSAQSQATINLRGAGSDRTLVLLNGKRMPGSPTLGGTAVNLNTIPTAAIERIEVLTD
GASAVYGSDAVAGVVNIILKKGFEGLEVSATSSQPVQDGGEEWKTQIVGGAVGEKGSVTFSFEHLNREIIYQRDRWFSSS
SNVLAPKFDDTTGVSTYARNFLDGKTGQFKPMTACDNPKMVGGGHIYDAGDGDYVCGYDFTAEAADHAARSYTAGYVNAE
YELSDEIVFQGLGLFSRNETFGRYAPAAGWFNVAPGQVEVKNYDANGKYTGNSLNENAGRAYYRFTDVGTRDAKTVDYST
DIQLGLVGTHDSFGWDFTYHYNLAENSNYGTGYVHRPTVERYVKDGIFNFGPEGNSASVIADMAHKTLKQDIMEFQSVNA
GVNFEAIELPAGNIGWYIGTEALQYKYEANVDAQTAAGDVIGSSGNGASGDRDVYALFAESIIPVTEDLELNLAYRYDNY
SDFGSATTPKVALRYQLLDDVVFRASWGQGFRAPSLSDLIASDSFSADTATDYHYCDVLGTNVADCKAKQYDVTRTANKE
LQPETSNFYNLGLVWDITDKLSTKIEYYNLDIKDVITFVSLDSLLKEEQKVGYGNLSRGEIKRVGDNPNGKLLSATTPKA
NGNGFDTSGIDFNLTYSGFETTIGDFSSSYDLSYILSYNEEEYFDGPVNDKIGRNGMPEFRFTWVIDWSYGDHSASILTQ
YIDGQSEKTDPNTYAQVGSLSSQTTFDISYGYATPWEGKISLGIRNLTNEDPVLDSDLKYDASLYNLYGRTFTATYTQKF

Sequences:

>Translated_800_residues
MSVADVLRRSNLNSFGSTSERSGSSAQSQATINLRGAGSDRTLVLLNGKRMPGSPTLGGTAVNLNTIPTAAIERIEVLTD
GASAVYGSDAVAGVVNIILKKGFEGLEVSATSSQPVQDGGEEWKTQIVGGAVGEKGSVTFSFEHLNREIIYQRDRWFSSS
SNVLAPKFDDTTGVSTYARNFLDGKTGQFKPMTACDNPKMVGGGHIYDAGDGDYVCGYDFTAEAADHAARSYTAGYVNAE
YELSDEIVFQGLGLFSRNETFGRYAPAAGWFNVAPGQVEVKNYDANGKYTGNSLNENAGRAYYRFTDVGTRDAKTVDYST
DIQLGLVGTHDSFGWDFTYHYNLAENSNYGTGYVHRPTVERYVKDGIFNFGPEGNSASVIADMAHKTLKQDIMEFQSVNA
GVNFEAIELPAGNIGWYIGTEALQYKYEANVDAQTAAGDVIGSSGNGASGDRDVYALFAESIIPVTEDLELNLAYRYDNY
SDFGSATTPKVALRYQLLDDVVFRASWGQGFRAPSLSDLIASDSFSADTATDYHYCDVLGTNVADCKAKQYDVTRTANKE
LQPETSNFYNLGLVWDITDKLSTKIEYYNLDIKDVITFVSLDSLLKEEQKVGYGNLSRGEIKRVGDNPNGKLLSATTPKA
NGNGFDTSGIDFNLTYSGFETTIGDFSSSYDLSYILSYNEEEYFDGPVNDKIGRNGMPEFRFTWVIDWSYGDHSASILTQ
YIDGQSEKTDPNTYAQVGSLSSQTTFDISYGYATPWEGKISLGIRNLTNEDPVLDSDLKYDASLYNLYGRTFTATYTQKF
>Mature_799_residues
SVADVLRRSNLNSFGSTSERSGSSAQSQATINLRGAGSDRTLVLLNGKRMPGSPTLGGTAVNLNTIPTAAIERIEVLTDG
ASAVYGSDAVAGVVNIILKKGFEGLEVSATSSQPVQDGGEEWKTQIVGGAVGEKGSVTFSFEHLNREIIYQRDRWFSSSS
NVLAPKFDDTTGVSTYARNFLDGKTGQFKPMTACDNPKMVGGGHIYDAGDGDYVCGYDFTAEAADHAARSYTAGYVNAEY
ELSDEIVFQGLGLFSRNETFGRYAPAAGWFNVAPGQVEVKNYDANGKYTGNSLNENAGRAYYRFTDVGTRDAKTVDYSTD
IQLGLVGTHDSFGWDFTYHYNLAENSNYGTGYVHRPTVERYVKDGIFNFGPEGNSASVIADMAHKTLKQDIMEFQSVNAG
VNFEAIELPAGNIGWYIGTEALQYKYEANVDAQTAAGDVIGSSGNGASGDRDVYALFAESIIPVTEDLELNLAYRYDNYS
DFGSATTPKVALRYQLLDDVVFRASWGQGFRAPSLSDLIASDSFSADTATDYHYCDVLGTNVADCKAKQYDVTRTANKEL
QPETSNFYNLGLVWDITDKLSTKIEYYNLDIKDVITFVSLDSLLKEEQKVGYGNLSRGEIKRVGDNPNGKLLSATTPKAN
GNGFDTSGIDFNLTYSGFETTIGDFSSSYDLSYILSYNEEEYFDGPVNDKIGRNGMPEFRFTWVIDWSYGDHSASILTQY
IDGQSEKTDPNTYAQVGSLSSQTTFDISYGYATPWEGKISLGIRNLTNEDPVLDSDLKYDASLYNLYGRTFTATYTQKF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=109, Percent_Identity=39.4495412844037, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788478, Length=114, Percent_Identity=36.8421052631579, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 87472; Mature: 87340

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVADVLRRSNLNSFGSTSERSGSSAQSQATINLRGAGSDRTLVLLNGKRMPGSPTLGGT
CCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCE
AVNLNTIPTAAIERIEVLTDGASAVYGSDAVAGVVNIILKKGFEGLEVSATSSQPVQDGG
EEEECCCCHHHHHHHHEEECCCCEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
EEWKTQIVGGAVGEKGSVTFSFEHLNREIIYQRDRWFSSSSNVLAPKFDDTTGVSTYARN
HHHHHEEECCCCCCCCCEEEEHHHCCCEEEEECCCCCCCCCCEECCCCCCCCCHHHHHHH
FLDGKTGQFKPMTACDNPKMVGGGHIYDAGDGDYVCGYDFTAEAADHAARSYTAGYVNAE
HHCCCCCCCCCCCCCCCCCEECCCEEEECCCCCEEECCCCCHHHHHHHHHHEECEEEEEE
YELSDEIVFQGLGLFSRNETFGRYAPAAGWFNVAPGQVEVKNYDANGKYTGNSLNENAGR
EECCHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCCCCCCCCCCCCCE
AYYRFTDVGTRDAKTVDYSTDIQLGLVGTHDSFGWDFTYHYNLAENSNYGTGYVHRPTVE
EEEEEECCCCCCCCEEEECCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCEEECCHHH
RYVKDGIFNFGPEGNSASVIADMAHKTLKQDIMEFQSVNAGVNFEAIELPAGNIGWYIGT
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECC
EALQYKYEANVDAQTAAGDVIGSSGNGASGDRDVYALFAESIIPVTEDLELNLAYRYDNY
HHEEEEEECCCCCCCCCCCEECCCCCCCCCCCHHHEEEHHHHCCCCCCCEEEEEEEECCC
SDFGSATTPKVALRYQLLDDVVFRASWGQGFRAPSLSDLIASDSFSADTATDYHYCDVLG
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECC
TNVADCKAKQYDVTRTANKELQPETSNFYNLGLVWDITDKLSTKIEYYNLDIKDVITFVS
CCHHHCCCCCEECCCCCCCCCCCCCCCEEEEEEEEEECHHHCCEEEEEECCHHHHHHHHH
LDSLLKEEQKVGYGNLSRGEIKRVGDNPNGKLLSATTPKANGNGFDTSGIDFNLTYSGFE
HHHHHHHHHHCCCCCCCCCHHEECCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCH
TTIGDFSSSYDLSYILSYNEEEYFDGPVNDKIGRNGMPEFRFTWVIDWSYGDHSASILTQ
HHHHCCCCCCCEEEEEECCCHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHH
YIDGQSEKTDPNTYAQVGSLSSQTTFDISYGYATPWEGKISLGIRNLTNEDPVLDSDLKY
HHCCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCC
DASLYNLYGRTFTATYTQKF
CHHHHHHCCCEEEEEEEECC
>Mature Secondary Structure 
SVADVLRRSNLNSFGSTSERSGSSAQSQATINLRGAGSDRTLVLLNGKRMPGSPTLGGT
CHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCE
AVNLNTIPTAAIERIEVLTDGASAVYGSDAVAGVVNIILKKGFEGLEVSATSSQPVQDGG
EEEECCCCHHHHHHHHEEECCCCEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
EEWKTQIVGGAVGEKGSVTFSFEHLNREIIYQRDRWFSSSSNVLAPKFDDTTGVSTYARN
HHHHHEEECCCCCCCCCEEEEHHHCCCEEEEECCCCCCCCCCEECCCCCCCCCHHHHHHH
FLDGKTGQFKPMTACDNPKMVGGGHIYDAGDGDYVCGYDFTAEAADHAARSYTAGYVNAE
HHCCCCCCCCCCCCCCCCCEECCCEEEECCCCCEEECCCCCHHHHHHHHHHEECEEEEEE
YELSDEIVFQGLGLFSRNETFGRYAPAAGWFNVAPGQVEVKNYDANGKYTGNSLNENAGR
EECCHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCCCCCCCCCCCCCE
AYYRFTDVGTRDAKTVDYSTDIQLGLVGTHDSFGWDFTYHYNLAENSNYGTGYVHRPTVE
EEEEEECCCCCCCCEEEECCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCEEECCHHH
RYVKDGIFNFGPEGNSASVIADMAHKTLKQDIMEFQSVNAGVNFEAIELPAGNIGWYIGT
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECC
EALQYKYEANVDAQTAAGDVIGSSGNGASGDRDVYALFAESIIPVTEDLELNLAYRYDNY
HHEEEEEECCCCCCCCCCCEECCCCCCCCCCCHHHEEEHHHHCCCCCCCEEEEEEEECCC
SDFGSATTPKVALRYQLLDDVVFRASWGQGFRAPSLSDLIASDSFSADTATDYHYCDVLG
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECC
TNVADCKAKQYDVTRTANKELQPETSNFYNLGLVWDITDKLSTKIEYYNLDIKDVITFVS
CCHHHCCCCCEECCCCCCCCCCCCCCCEEEEEEEEEECHHHCCEEEEEECCHHHHHHHHH
LDSLLKEEQKVGYGNLSRGEIKRVGDNPNGKLLSATTPKANGNGFDTSGIDFNLTYSGFE
HHHHHHHHHHCCCCCCCCCHHEECCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCH
TTIGDFSSSYDLSYILSYNEEEYFDGPVNDKIGRNGMPEFRFTWVIDWSYGDHSASILTQ
HHHHCCCCCCCEEEEEECCCHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHH
YIDGQSEKTDPNTYAQVGSLSSQTTFDISYGYATPWEGKISLGIRNLTNEDPVLDSDLKY
HHCCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCC
DASLYNLYGRTFTATYTQKF
CHHHHHHCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11598060 [H]