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The map label for this gene is uvrC

Identifier: 126174774

GI number: 126174774

Start: 2999137

End: 3000966

Strand: Reverse

Name: uvrC

Synonym: Sbal_2561

Alternate gene names: 126174774

Gene position: 3000966-2999137 (Counterclockwise)

Preceding gene: 126174775

Following gene: 126174773

Centisome position: 58.53

GC content: 47.49

Gene sequence:

>1830_bases
ATGTCGAATGAATTTAACGCCCAAAGTTTTTTACGTACGGTTTCATCCTCCGCTGGGGTTTATCGCATGTATGACGTCAA
GAATGACGTCATTTATGTGGGTAAAGCCAAAGATCTCAAAAAACGGCTTACCTCGTATTTTCGTAAAAACCTCGCTAATG
TTAAGACCCAAGCCTTAGTCTCGCATATTCACCATATTAATGTGACGCTGACCCACAGCGAAACCGATGCTCTGTTGCTT
GAGAATGATTACATCAAGCAATACATGCCAAAATACAATGTGTTATTGCGTGATGACAAATCTTATCCTTACATACTGTT
AAGCCAGCACGAACACCCAAGGCTTGCTTATCATCGTGGTCCGCAGCGGGAAAAAGGCCACTATTTTGGCCCTTATCCTA
ACGGCGGCGCCGTGCGTGAAAGCCTGCATTTAATGCAGAAGCTGTTTCCAATTCGTCAATGTGACGACCTTTACTACAAG
TCTCGCTCACGCCCCTGTTTACAATATCAACTTTCCCGTTGTAGCGCGCCCTGTGTGGGTAAAGTCAGCAACGCTGATTA
CGACGAGCAAGTGAAACTCGCCAGCCTGTTTTTAAAGGGCAAAGATCAGCAAGTGATCAGCGCCTTGGTTGACAAAATGG
AGCTTGCGGCTGAGCGACAAGCTTATGAGCAAGCTGCACGATTTCGCGATCAGATCATGGCGCTGCGTAAAGTCGCCGAA
CAACAGGAAGTATCGAATAATAAAGGCGATATGGATGTCATCGGTGTGCATTATTCGTCGGGCATCGCCTGTTTCCATTT
GCTGTTTATCCGCGAGGGTAAAATTTTTGGTAGTCGCAGCTATTATCCTTCTGTGCCGGCCCAAACCGATATGGACGAAG
TGCTGCGCTCTTTCATCCTGCAGTTTTATTTAAATGCGGATATTCAACGCACGATCCCAAAGGAAGTGGTGATTAGCCAC
AACTTTGAAGAATTACATGAACTTGAAGCGGCGGTTTCTGAGGCGCTAGATAAAAAGTTTTCGATTAAGACCAATGTGCG
CGCCGACAGGGCAAGTTTCTTGCGGTTAGCGGTGACCAATGCGACGAATGCCGTGGTTACGCGCTTGTCCCATAAAAACA
CGGTCGAGCAGCGTTTTGTGTTACTCGAAGAAATCCTTGAATTGAGTACGCCTATTCAGCGGATGGAATGTTTTGATATC
AGTCATACCATGGGGGAGAGCACGGTTGCCTCCTGTGTGGTGTTCAATCGGGAAGGGCCGCATAAAGGTGAATATCGTCG
CTATAATATCGAGGGTATTACACCGGGCGATGATTACGCGGCAATGAAGCAAGCGGTGAGCCGACGCTTCGATAAGATTG
AGGCGGGCGGTAAAATCCCTGACATTCTGTTTATCGATGGTGGACTTGGGCAGTTGCGTATCGCCCAGAAGATAGTGGAT
GAAAAGTTTGTCCATTTAGATAAAGCACCGCAGCTCATTGGGGTGGCGAAAGGTGAGGGCCGTAAACCTGGGCTCGAAAC
CTTGATTTTAGGGGATACAGAAACCAGCTTTTCCCTCGAAGGTGATTCGCCCGCGTTGCACCTGATTCAACATATTCGCG
ATGAGTCCCATCGATTCGCGATAGCTGGCCATCGTAATCGTCGCCAGAAAACCCGCAATACTTCCACATTGGAATCTATT
CCAGGAATTGGCCCTAAACGCCGTAAAGCTTTGTTACAGCATTTAGGTGGGTTGCAAGAAGTGAAAGGGGCAAGTGTGGC
GGAATTAGTCAAAGTACCAGGGATCAGCATAGAAATGGCACAAACCATTCATGATGCATTGCGAGGGTGA

Upstream 100 bases:

>100_bases
TAAGTGGATTGCGTTGATCGATGGCTTGAGTCGAGTGAGTTCGTGGGTTAAATGTTGCTATGTTGTCTGTGTTAAGTCTA
CAAAACTGTGGGTGTAAATG

Downstream 100 bases:

>100_bases
TAAAATTAAGGCAAGATTGGCGCTGCTTTTGACTAACTGGTTTGATCATGCCGTTTAACTTACCTATAGCATTAACTCTT
TTCAGGCTTTTTTTACTGCC

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MSNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALVSHIHHINVTLTHSETDALLL
ENDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRGPQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYK
SRSRPCLQYQLSRCSAPCVGKVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAE
QQEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFILQFYLNADIQRTIPKEVVISH
NFEELHELEAAVSEALDKKFSIKTNVRADRASFLRLAVTNATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDI
SHTMGESTVASCVVFNREGPHKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVD
EKFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFAIAGHRNRRQKTRNTSTLESI
PGIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMAQTIHDALRG

Sequences:

>Translated_609_residues
MSNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALVSHIHHINVTLTHSETDALLL
ENDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRGPQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYK
SRSRPCLQYQLSRCSAPCVGKVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAE
QQEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFILQFYLNADIQRTIPKEVVISH
NFEELHELEAAVSEALDKKFSIKTNVRADRASFLRLAVTNATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDI
SHTMGESTVASCVVFNREGPHKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVD
EKFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFAIAGHRNRRQKTRNTSTLESI
PGIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMAQTIHDALRG
>Mature_608_residues
SNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALVSHIHHINVTLTHSETDALLLE
NDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRGPQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKS
RSRPCLQYQLSRCSAPCVGKVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAEQ
QEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFILQFYLNADIQRTIPKEVVISHN
FEELHELEAAVSEALDKKFSIKTNVRADRASFLRLAVTNATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDIS
HTMGESTVASCVVFNREGPHKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVDE
KFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFAIAGHRNRRQKTRNTSTLESIP
GIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMAQTIHDALRG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain

Homologues:

Organism=Escherichia coli, GI87081999, Length=610, Percent_Identity=57.0491803278689, Blast_Score=726, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UVRC_SHEB5 (A3D5P1)

Other databases:

- EMBL:   CP000563
- RefSeq:   YP_001050923.1
- ProteinModelPortal:   A3D5P1
- STRING:   A3D5P1
- GeneID:   4843633
- GenomeReviews:   CP000563_GR
- KEGG:   sbl:Sbal_2561
- NMPDR:   fig|325240.3.peg.2044
- eggNOG:   COG0322
- HOGENOM:   HBG566029
- OMA:   DVLYVGK
- PhylomeDB:   A3D5P1
- ProtClustDB:   PRK00558
- GO:   GO:0005737
- HAMAP:   MF_00203
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305
- SMART:   SM00465
- SMART:   SM00278
- TIGRFAMs:   TIGR00194

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N; SSF47781 RuvA_2_like; SSF46600 UvrB_C; SSF82771 UvrC_N

EC number: NA

Molecular weight: Translated: 68845; Mature: 68713

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50151 UVR; PS50164 UVRC_1; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALV
CCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
SHIHHINVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRG
HHHHHEEEEEEECCCCEEEEECHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCHHHCCC
PQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRSRPCLQYQLSRCSAPCVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
KVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAE
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFIL
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHH
QFYLNADIQRTIPKEVVISHNFEELHELEAAVSEALDKKFSIKTNVRADRASFLRLAVTN
HHHHCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHEEEEEECC
ATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDISHTMGESTVASCVVFNREGP
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHEEEECCCCC
HKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVD
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
EKFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFA
HHHHHHCCCCCEEEECCCCCCCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHCCCCEEE
IAGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMA
EECCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHCCCCCHHHH
QTIHDALRG
HHHHHHHCC
>Mature Secondary Structure 
SNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALV
CCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
SHIHHINVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRG
HHHHHEEEEEEECCCCEEEEECHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCHHHCCC
PQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRSRPCLQYQLSRCSAPCVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
KVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAE
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFIL
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHH
QFYLNADIQRTIPKEVVISHNFEELHELEAAVSEALDKKFSIKTNVRADRASFLRLAVTN
HHHHCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHEEEEEECC
ATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDISHTMGESTVASCVVFNREGP
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHEEEECCCCC
HKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVD
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
EKFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFA
HHHHHHCCCCCEEEECCCCCCCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHCCCCEEE
IAGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMA
EECCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHCCCCCHHHH
QTIHDALRG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA