Click here to switch to the map view.

The map label for this gene is iciA [H]

Identifier: 126174769

GI number: 126174769

Start: 2992099

End: 2993034

Strand: Direct

Name: iciA [H]

Synonym: Sbal_2556

Alternate gene names: 126174769

Gene position: 2992099-2993034 (Clockwise)

Preceding gene: 126174767

Following gene: 126174771

Centisome position: 58.36

GC content: 51.18

Gene sequence:

>936_bases
ATGCTGGAATACGCCAATCTCAAAGCCCTCGCCGTTGTCGTCTCGGAAGGCGGTTTCGATCGCGCCGCTAAAGTGCTGCA
CATCACCCAGTCGGCGGTATCGCAACGCATTCGGCAGCTTGAGGAAAAAGTCGGTCAGTCATTACTTATTCGCTCCAATC
CCGTGGTCGCCACCCCCACAGGCAAACGCCTGCTGCGCCACTATTCACAGGTGCAATTACTTGAGAGTGAATTAAGAGCC
GAGATGGACGCCGACGATCCCAACCATCCAACCACAGTGCGCATCGCTGTGAATGCCGACAGTTTAGCCACTTGGTTTTT
ACCAGCGCTGGCAGGCATGTTCAGTCGCCACGCTTGGTTATTAGAATTGATCGTCGATGACGAGTCTTACACCCATCATC
TATTGAAAAACGGTGAAGCGGTCGGCTGCGTCACTACAACTGAGGTGCCGATGGCAGGTTGCAGCAGTGAGTTTTTAGGC
ACCATGGAATACTTATGTGTTGCCACGCCCGAATTTGCTGCCCGTTATTTTGGTGAGCCGAGTGACTCTAAATCACTTAG
CGACACTCAGCCATCTAACGACATTAGCCAAGCCCAGTTAGCGAAAGCGCCAGCAGTGGTGTTTTCCACCAAAGATAAGC
TGCACGAGAAGTTTCTCGCCCAATATTTCAATATGACGCCAGGGCAATGGTGGCAACATACGATCCCCTCTTCAGAGAGC
TTTTTAGAAGCGATTAACTTGAGCTTAGGTTATGGGCTTGTCGGTCACCTGCAAGCTAAGCCGTTAATCGATAGAGGGAT
ATTGATTGAGCTCACGCCAGAACGGCGTATGCGTGTGCCACTGTTTTGGCAGCATTGGAATATCAAAGCCAAGCAAACGA
CACTGGTCTATCGCGCCCTTGCAGTAACAGCGCAACACAATTTGCTACAGGCATGA

Upstream 100 bases:

>100_bases
CGCTAGCATAGTCAAAACAACAAAATTAATATAACTAATGTTTTTTATGTATCATAAGTAAAATTAATAACCATCAAACA
TACATCGATTAAGGATGACT

Downstream 100 bases:

>100_bases
TTTGTTGCATCAAGAATGAACGCACAACCCGCATGAATCTTCAGCGATTTACCCGCGATGGTGTTTAACGCGGAGTGATG
ATTCTCATAGCGGCGCCTTT

Product: chromosome replication initiation inhibitor protein

Products: NA

Alternate protein names: OriC replication inhibitor [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MLEYANLKALAVVVSEGGFDRAAKVLHITQSAVSQRIRQLEEKVGQSLLIRSNPVVATPTGKRLLRHYSQVQLLESELRA
EMDADDPNHPTTVRIAVNADSLATWFLPALAGMFSRHAWLLELIVDDESYTHHLLKNGEAVGCVTTTEVPMAGCSSEFLG
TMEYLCVATPEFAARYFGEPSDSKSLSDTQPSNDISQAQLAKAPAVVFSTKDKLHEKFLAQYFNMTPGQWWQHTIPSSES
FLEAINLSLGYGLVGHLQAKPLIDRGILIELTPERRMRVPLFWQHWNIKAKQTTLVYRALAVTAQHNLLQA

Sequences:

>Translated_311_residues
MLEYANLKALAVVVSEGGFDRAAKVLHITQSAVSQRIRQLEEKVGQSLLIRSNPVVATPTGKRLLRHYSQVQLLESELRA
EMDADDPNHPTTVRIAVNADSLATWFLPALAGMFSRHAWLLELIVDDESYTHHLLKNGEAVGCVTTTEVPMAGCSSEFLG
TMEYLCVATPEFAARYFGEPSDSKSLSDTQPSNDISQAQLAKAPAVVFSTKDKLHEKFLAQYFNMTPGQWWQHTIPSSES
FLEAINLSLGYGLVGHLQAKPLIDRGILIELTPERRMRVPLFWQHWNIKAKQTTLVYRALAVTAQHNLLQA
>Mature_311_residues
MLEYANLKALAVVVSEGGFDRAAKVLHITQSAVSQRIRQLEEKVGQSLLIRSNPVVATPTGKRLLRHYSQVQLLESELRA
EMDADDPNHPTTVRIAVNADSLATWFLPALAGMFSRHAWLLELIVDDESYTHHLLKNGEAVGCVTTTEVPMAGCSSEFLG
TMEYLCVATPEFAARYFGEPSDSKSLSDTQPSNDISQAQLAKAPAVVFSTKDKLHEKFLAQYFNMTPGQWWQHTIPSSES
FLEAINLSLGYGLVGHLQAKPLIDRGILIELTPERRMRVPLFWQHWNIKAKQTTLVYRALAVTAQHNLLQA

Specific function: Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789283, Length=298, Percent_Identity=38.5906040268456, Blast_Score=191, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR017685
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34652; Mature: 34652

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEYANLKALAVVVSEGGFDRAAKVLHITQSAVSQRIRQLEEKVGQSLLIRSNPVVATPT
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEECCC
GKRLLRHYSQVQLLESELRAEMDADDPNHPTTVRIAVNADSLATWFLPALAGMFSRHAWL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHEE
LELIVDDESYTHHLLKNGEAVGCVTTTEVPMAGCSSEFLGTMEYLCVATPEFAARYFGEP
EEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCC
SDSKSLSDTQPSNDISQAQLAKAPAVVFSTKDKLHEKFLAQYFNMTPGQWWQHTIPSSES
CCCCCCCCCCCCCCHHHHHHHHCCEEEEECHHHHHHHHHHHHHCCCCCCHHHCCCCCHHH
FLEAINLSLGYGLVGHLQAKPLIDRGILIELTPERRMRVPLFWQHWNIKAKQTTLVYRAL
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHH
AVTAQHNLLQA
HHHHHHHHHCC
>Mature Secondary Structure
MLEYANLKALAVVVSEGGFDRAAKVLHITQSAVSQRIRQLEEKVGQSLLIRSNPVVATPT
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEECCC
GKRLLRHYSQVQLLESELRAEMDADDPNHPTTVRIAVNADSLATWFLPALAGMFSRHAWL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHEE
LELIVDDESYTHHLLKNGEAVGCVTTTEVPMAGCSSEFLGTMEYLCVATPEFAARYFGEP
EEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCC
SDSKSLSDTQPSNDISQAQLAKAPAVVFSTKDKLHEKFLAQYFNMTPGQWWQHTIPSSES
CCCCCCCCCCCCCCHHHHHHHHCCEEEEECHHHHHHHHHHHHHCCCCCCHHHCCCCCHHH
FLEAINLSLGYGLVGHLQAKPLIDRGILIELTPERRMRVPLFWQHWNIKAKQTTLVYRAL
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHH
AVTAQHNLLQA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9286976 [H]