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The map label for this gene is htpG

Identifier: 126174761

GI number: 126174761

Start: 2981258

End: 2983171

Strand: Reverse

Name: htpG

Synonym: Sbal_2548

Alternate gene names: 126174761

Gene position: 2983171-2981258 (Counterclockwise)

Preceding gene: 126174762

Following gene: 126174760

Centisome position: 58.18

GC content: 47.86

Gene sequence:

>1914_bases
ATGTCACAACAAGAAACTCATGGTTTTCAAACAGAAGTCAAACAGCTGTTGCATTTGATGATCCATTCTTTGTATTCCAA
CAAAGAAATTTTCTTGCGTGAACTGGTCTCCAACGCTGCGGATGCAGCGGACAAGCTGCGTTATCTGGCGTTGACCAATG
ACGCTCTGTATGAAGGCGACGGTGAACTGCGAGTCCGTATCAGTGCTGATAAAGAAAAAGGCACTGTGACCATCGAAGAC
AACGGCGTGGGTATGACCCGCGACGGCGTGATTGAGCATTTAGGCACAATTGCTAAGTCGGGCACCGCTGATTTCTTTAA
GAATCTATCGGGCGAATCTTCAAAGGATTCACAGTTAATCGGCCAGTTCGGTGTCGGTTTCTATTCAGCCTTTATCGTGG
CCAAGAAAGTCACTGTTCGCACTCGCGCTGCCGGTCATAAGGCCGATGAAGCCGTATTGTGGGAATCAGAAGGCGAGGGT
AACTTCACCGTTGATACCATCACTAAGGCGAGCCGTGGTACTGAAATCACCCTGCACCTGCGTGATGAAGAAAAAGAATT
TGCCGATGATTGGCGCCTACGTTCAATCATTACTAAGTACTCAGATCATATCTCTGTGCCAGTCGAAATGTGGCAAGAAG
GTACGCCAGAAAGTGATGGTGCTGATGGCGAAAAAATTCCAGCGACCGAAGGTCAATGGAAAGTCATGAACAAAGCGACT
GCTTTGTGGATGCGCAGCAAAGCTGACATCAGTGACGAAGAGTATCAAGAATTTTACAAACACATTTCCCACGATTATAC
CGACGCACTACTGTGGAGTCATAATCGGGTAGAAGGTAAGCAAGAATACACTAACCTATTGTATATTCCTGCAAAAGCAC
CTTGGGATATGTGGAACCGCGACCGTAAGCACGGCCTGAAACTGTTTGTGCAACGTGTGTTCATCATGGATGATGCTGAG
CAGTTTATGCCATCTTATCTGCGCTTTGTGCAGGGCTTAATTGATTCAAACGATCTGCCGCTGAACGTATCCCGCGAAAT
TTTGCAGGATAACCACGTGACCAAAGCGATGCGAACAGGTATCACCAAACGTGTGCTTGGCATGCTGGAAAAACTGGCGA
AAGACGATGCGGAAAAATATCAACAGTTCTGGGCTGAATTTGGCCAAGTGTTGAAAGAAGGGCCAGCGGAAGATTTCGCC
AACCGCGAACGTATCGCAGGCTTATTACGTTTTGCCTCGACCCATACGGGCAGTGCTGCGCCGACTGTGTCACTCGATGA
CTACATCAGCCGCATGAAAGAAGGCCAAACTAAGATTTATTACATCGTTGCCGACAGCCATGAAGCCGCCGCTAACAGCC
CGCATTTAGAGTTGTTACGTAAGAAAGGCATCGAAGTATTACTGATGTCAGAGCGTATCGACGAGTGGCTAATCAACCAC
TTAACTGAGTACAAAGAGAAACAACTGCACTCAGTGACCCGTGGTGACTTAGAGCTTGGCGAGCTGGAAGATGCAGCTGA
AAAAGAAGCGCAAGAAAAGCTTGAGCAAGAATCGGTAGCTTTAGTTGAACGCATTAAAGCGGCATTAGGCTCGAGTGTTG
CTGATGTGAAAGTCACGTCACGCTTAACCGACACCCCTGCTTGTGTAGTAGCGGGTGACGGCGAAATGTCGACTCAGATG
ATCAAGCTGATGCAAGCTGCCGGTCAACCAGTGCCAGAAGTGAAGCCAACATTTGAGATCAACCCAGCGCACCCATTAGT
GTCGCGCTTAAATGATCTTCAAGATGAAACCGCCTTTGCGGATTGGTCGAATCTGCTGCTGCAACAGGCGCAATTGTCTG
AAAAAGGTAGCCTTGCGGATCCATCGGCCTTTATCAAGCTGATGAACCAAATGTTACTGGCTAACATGAAGTAA

Upstream 100 bases:

>100_bases
CGTTTTAGCCCTTGCCCTTGAAAAGCAAATTTGGAGCCCCATTTAAGTAAACACTAAGCGTTACTTTTACCAAATTACGT
AACAAATAAAGGAAAATTTC

Downstream 100 bases:

>100_bases
ATGACTATCGGGGCCTTTCTTTGAACGGCCCCGATATTGTTTCTAGTGTAGGAAGAGTGGTTTATGCCTAGAGCACTCCA
CTTCCGTGTTGCATCAATTC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIED
NGVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEG
NFTVDTITKASRGTEITLHLRDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKAT
ALWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNRDRKHGLKLFVQRVFIMDDAE
QFMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFA
NRERIAGLLRFASTHTGSAAPTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
LTEYKEKQLHSVTRGDLELGELEDAAEKEAQEKLEQESVALVERIKAALGSSVADVKVTSRLTDTPACVVAGDGEMSTQM
IKLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDETAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK

Sequences:

>Translated_637_residues
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIED
NGVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEG
NFTVDTITKASRGTEITLHLRDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKAT
ALWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNRDRKHGLKLFVQRVFIMDDAE
QFMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFA
NRERIAGLLRFASTHTGSAAPTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
LTEYKEKQLHSVTRGDLELGELEDAAEKEAQEKLEQESVALVERIKAALGSSVADVKVTSRLTDTPACVVAGDGEMSTQM
IKLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDETAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK
>Mature_636_residues
SQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIEDN
GVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEGN
FTVDTITKASRGTEITLHLRDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKATA
LWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNRDRKHGLKLFVQRVFIMDDAEQ
FMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFAN
RERIAGLLRFASTHTGSAAPTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINHL
TEYKEKQLHSVTRGDLELGELEDAAEKEAQEKLEQESVALVERIKAALGSSVADVKVTSRLTDTPACVVAGDGEMSTQMI
KLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDETAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=681, Percent_Identity=37.4449339207048, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI4507677, Length=687, Percent_Identity=37.2634643377001, Blast_Score=421, Evalue=1e-117,
Organism=Homo sapiens, GI155722983, Length=646, Percent_Identity=33.9009287925697, Blast_Score=368, Evalue=1e-101,
Organism=Homo sapiens, GI154146191, Length=408, Percent_Identity=37.5, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI153792590, Length=408, Percent_Identity=37.5, Blast_Score=265, Evalue=1e-70,
Organism=Escherichia coli, GI1786679, Length=634, Percent_Identity=68.2965299684543, Blast_Score=884, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=668, Percent_Identity=37.874251497006, Blast_Score=435, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17542208, Length=665, Percent_Identity=37.8947368421053, Blast_Score=415, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI115535205, Length=647, Percent_Identity=31.2210200927357, Blast_Score=315, Evalue=5e-86,
Organism=Caenorhabditis elegans, GI115535167, Length=445, Percent_Identity=34.3820224719101, Blast_Score=259, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=37.0588235294118, Blast_Score=432, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6325016, Length=409, Percent_Identity=37.8973105134474, Blast_Score=277, Evalue=4e-75,
Organism=Drosophila melanogaster, GI17647529, Length=684, Percent_Identity=37.8654970760234, Blast_Score=457, Evalue=1e-129,
Organism=Drosophila melanogaster, GI21357739, Length=680, Percent_Identity=37.5, Blast_Score=413, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24586016, Length=648, Percent_Identity=33.9506172839506, Blast_Score=359, Evalue=4e-99,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_SHEB5 (A3D5M8)

Other databases:

- EMBL:   CP000563
- RefSeq:   YP_001050910.1
- STRING:   A3D5M8
- GeneID:   4843006
- GenomeReviews:   CP000563_GR
- KEGG:   sbl:Sbal_2548
- NMPDR:   fig|325240.3.peg.4248
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   TEGYWKV
- PhylomeDB:   A3D5M8
- ProtClustDB:   PRK05218
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71650; Mature: 71518

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGD
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECC
GELRVRISADKEKGTVTIEDNGVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLI
CCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHH
GQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEGNFTVDTITKASRGTEITLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEHHHCCCCCEEEEEE
RDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKAT
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNR
HHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHCCEEEECCCCCHHHHCC
DRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHH
ITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFANRERIAGLLRFASTHTGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHH
LTEYKEKQLHSVTRGDLELGELEDAAEKEAQEKLEQESVALVERIKAALGSSVADVKVTS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHH
RLTDTPACVVAGDGEMSTQMIKLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDETAFA
HCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHH
DWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGD
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECC
GELRVRISADKEKGTVTIEDNGVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLI
CCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHH
GQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEGNFTVDTITKASRGTEITLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEHHHCCCCCEEEEEE
RDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKAT
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNR
HHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHCCEEEECCCCCHHHHCC
DRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHH
ITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFANRERIAGLLRFASTHTGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHH
LTEYKEKQLHSVTRGDLELGELEDAAEKEAQEKLEQESVALVERIKAALGSSVADVKVTS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHH
RLTDTPACVVAGDGEMSTQMIKLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDETAFA
HCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHH
DWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA