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The map label for this gene is yafC [C]

Identifier: 126174633

GI number: 126174633

Start: 2817195

End: 2818073

Strand: Direct

Name: yafC [C]

Synonym: Sbal_2420

Alternate gene names: 126174633

Gene position: 2817195-2818073 (Clockwise)

Preceding gene: 126174630

Following gene: 126174635

Centisome position: 54.94

GC content: 49.83

Gene sequence:

>879_bases
ATGTATCTCTGGGATGGCATTTCTGAATTTGTCGCAGTGGCCGAAGCCGAAAGTTTTACCTTAGCGGCGCAGCGACTGAA
TATCTCCACTGCCCACGTGAGCCGCCAAGTCAGCGCCTTAGAGAATCGCCTCGGCACTAAGCTGTTTTACCGCACCACCC
GCAAAGTGTCACTAACCGAAGAAGGCACCATTTATTATCGTCATTGCCGCCAATTACAAACCGGGTTAGAAGAAGCCGAG
CGCGCCATCTCAAACCTAAAGGACTCACCCCAAGGCTTAGTCAAGCTCACCGCTCCCGTGGCCTATGGCGAGAAATTTAT
CATGCCGTTACTCAATGATTTTATGGTGCAATATCCCAGCGTTGAATTTAGTGTCGACTTGACCAATCGCACCTTAGACT
TGATTGAAGGTGGTTACGATCTGGCCATTCGCCTCGGTAAACTCGCCGATTCGAGTTTAATGGCCAAACCCTTAAGCAGC
CGTACTCACTATGTGGCCGCCTCACCAAGTTATGTGGAAAAGTACGGTCAGCCCCATACGCTATCAGAGCTTAGCCAGCA
CAACTGCTTGATTGGCAATCACAATTACTGGCGCTTTGTGGAGAATGGCCGCGAGCGCAATATTAAAGTGCGCGGCAATC
TCAATTGTAACAGCGGCTACGCACTCAGGGATGCGGCGTTAAAGGGAATTGGCATAGTACAACTACCTGATTATTATATT
GAAGATGATATAAATGCGGGACGTTTGCTGTCCTTACTCGACGGTCACCGCGAAGCCAAAGAAGGCATTTGGGCGATCTA
TCCGCAAAACCGCCACCTGTCGGCCAAGATCCGCGTATTAGTCGATTACCTCGCCGAAAAACTCATCGAACAGGACTAA

Upstream 100 bases:

>100_bases
GATGCTACTGCACTGATGCTAATTAATAATAAGATTGTATTTGTTTCTCAGCGAGAGACAATCTAGTATTCAAGCAATTC
ATTTTTACTGAGCAACAACA

Downstream 100 bases:

>100_bases
TCTTTTTCTGAACAGCCGGTTGTTGAGCGGATTACTCAGTTCGAACAAACGAAGCGATAACAGACAACACCCAGCAAACT
AGCGCCAGTTTTCCCGTAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MYLWDGISEFVAVAEAESFTLAAQRLNISTAHVSRQVSALENRLGTKLFYRTTRKVSLTEEGTIYYRHCRQLQTGLEEAE
RAISNLKDSPQGLVKLTAPVAYGEKFIMPLLNDFMVQYPSVEFSVDLTNRTLDLIEGGYDLAIRLGKLADSSLMAKPLSS
RTHYVAASPSYVEKYGQPHTLSELSQHNCLIGNHNYWRFVENGRERNIKVRGNLNCNSGYALRDAALKGIGIVQLPDYYI
EDDINAGRLLSLLDGHREAKEGIWAIYPQNRHLSAKIRVLVDYLAEKLIEQD

Sequences:

>Translated_292_residues
MYLWDGISEFVAVAEAESFTLAAQRLNISTAHVSRQVSALENRLGTKLFYRTTRKVSLTEEGTIYYRHCRQLQTGLEEAE
RAISNLKDSPQGLVKLTAPVAYGEKFIMPLLNDFMVQYPSVEFSVDLTNRTLDLIEGGYDLAIRLGKLADSSLMAKPLSS
RTHYVAASPSYVEKYGQPHTLSELSQHNCLIGNHNYWRFVENGRERNIKVRGNLNCNSGYALRDAALKGIGIVQLPDYYI
EDDINAGRLLSLLDGHREAKEGIWAIYPQNRHLSAKIRVLVDYLAEKLIEQD
>Mature_292_residues
MYLWDGISEFVAVAEAESFTLAAQRLNISTAHVSRQVSALENRLGTKLFYRTTRKVSLTEEGTIYYRHCRQLQTGLEEAE
RAISNLKDSPQGLVKLTAPVAYGEKFIMPLLNDFMVQYPSVEFSVDLTNRTLDLIEGGYDLAIRLGKLADSSLMAKPLSS
RTHYVAASPSYVEKYGQPHTLSELSQHNCLIGNHNYWRFVENGRERNIKVRGNLNCNSGYALRDAALKGIGIVQLPDYYI
EDDINAGRLLSLLDGHREAKEGIWAIYPQNRHLSAKIRVLVDYLAEKLIEQD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=282, Percent_Identity=37.2340425531915, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=32.6388888888889, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1789440, Length=281, Percent_Identity=30.2491103202847, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI87081978, Length=287, Percent_Identity=29.2682926829268, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=29.4915254237288, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=28.8194444444444, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787589, Length=285, Percent_Identity=28.0701754385965, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786448, Length=281, Percent_Identity=24.1992882562278, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790011, Length=304, Percent_Identity=25.3289473684211, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788706, Length=189, Percent_Identity=30.1587301587302, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789173, Length=249, Percent_Identity=26.9076305220884, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=155, Percent_Identity=30.9677419354839, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788297, Length=113, Percent_Identity=33.6283185840708, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790783, Length=266, Percent_Identity=25.9398496240602, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=166, Percent_Identity=28.3132530120482, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=26.1168384879725, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787806, Length=271, Percent_Identity=23.9852398523985, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32986; Mature: 32986

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLWDGISEFVAVAEAESFTLAAQRLNISTAHVSRQVSALENRLGTKLFYRTTRKVSLTE
CCCCCCHHHHHHHHCCCHHEEHHHHCCCHHHHHHHHHHHHHHHHCCHHEEEECCEEEECC
EGTIYYRHCRQLQTGLEEAERAISNLKDSPQGLVKLTAPVAYGEKFIMPLLNDFMVQYPS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHCCHHHHHHHHHHHHHHCCC
VEFSVDLTNRTLDLIEGGYDLAIRLGKLADSSLMAKPLSSRTHYVAASPSYVEKYGQPHT
EEEEEEECCCCHHHHCCCCEEEEEECHHCCCHHHHCCCCCCCEEEECCCHHHHHCCCCCC
LSELSQHNCLIGNHNYWRFVENGRERNIKVRGNLNCNSGYALRDAALKGIGIVQLPDYYI
HHHHHHCCCEECCCCEEEEECCCCCCEEEEEECCCCCCCCEEHHHHHCCCEEEECCCEEE
EDDINAGRLLSLLDGHREAKEGIWAIYPQNRHLSAKIRVLVDYLAEKLIEQD
CCCCCHHHHHHHHHCCHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYLWDGISEFVAVAEAESFTLAAQRLNISTAHVSRQVSALENRLGTKLFYRTTRKVSLTE
CCCCCCHHHHHHHHCCCHHEEHHHHCCCHHHHHHHHHHHHHHHHCCHHEEEECCEEEECC
EGTIYYRHCRQLQTGLEEAERAISNLKDSPQGLVKLTAPVAYGEKFIMPLLNDFMVQYPS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHCCHHHHHHHHHHHHHHCCC
VEFSVDLTNRTLDLIEGGYDLAIRLGKLADSSLMAKPLSSRTHYVAASPSYVEKYGQPHT
EEEEEEECCCCHHHHCCCCEEEEEECHHCCCHHHHCCCCCCCEEEECCCHHHHHCCCCCC
LSELSQHNCLIGNHNYWRFVENGRERNIKVRGNLNCNSGYALRDAALKGIGIVQLPDYYI
HHHHHHCCCEECCCCEEEEECCCCCCEEEEEECCCCCCCCEEHHHHHCCCEEEECCCEEE
EDDINAGRLLSLLDGHREAKEGIWAIYPQNRHLSAKIRVLVDYLAEKLIEQD
CCCCCHHHHHHHHHCCHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]