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The map label for this gene is crr [H]

Identifier: 126174575

GI number: 126174575

Start: 2749492

End: 2750001

Strand: Direct

Name: crr [H]

Synonym: Sbal_2362

Alternate gene names: 126174575

Gene position: 2749492-2750001 (Clockwise)

Preceding gene: 126174574

Following gene: 126174577

Centisome position: 53.62

GC content: 47.25

Gene sequence:

>510_bases
ATGGGATTTTTAAGCCGAATTAGGCGCTTGGTATCGGGCCAGACTCAGTTAGCTGGCGGTATCATGGTATATGCCCCCGT
TTCCGGCGATATCGTCGCTATTGAAAAAGTCCCCGATGTGGTTTTTGCTGAGAAGATTGTCGGTGATGGCATTGCCATCG
CCCCCAAAGGCGAATTAATTCTTGCGCCTATTGACGGCACCATCGGAAAAATTTTTGAGACAAATCATGCCTTCAGCATT
GAGTCTCCCCAAGGTTTAGAATTATTTGTGCACTTTGGTGTCGGCACCGTCGAGCTGAGAGGTAAAGGTTTTAAACGTTT
AGCCCAAGAAGGCCAAGAAGTGAAAGTCGGCGATCCGATTTTGTCCTTCGATATTGATTATCTTAAAGATCAAGTCGACA
GCCTACTCACCCCTGTCGTGCTGGCAAACATGGAAGACGTCAAATATCTAGACAAGGCCCAAGGCAGTGTCACCGCAGGT
AAAGACGTGATCTTTACGGTACAGCTCTAA

Upstream 100 bases:

>100_bases
TACAGCAGTGTATAACAAGCTATAAATAGAGACATTTATTCGTTATGCTGCATTACAGAACAAAAACAATGACAAAAACA
AGCAAAAGAGGCTCTAGATT

Downstream 100 bases:

>100_bases
TTTAACCGTTTAACATGCATCGGTTGTGTTTTGAATAACAAAAGGCTGGCTCATAATCATGAGTCAGCCTTTTACGTTTT
TGAAAACTGAGCCTTCACAC

Product: PTS system glucose-specific transporter subunit

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Glc; EIII-Glc; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MGFLSRIRRLVSGQTQLAGGIMVYAPVSGDIVAIEKVPDVVFAEKIVGDGIAIAPKGELILAPIDGTIGKIFETNHAFSI
ESPQGLELFVHFGVGTVELRGKGFKRLAQEGQEVKVGDPILSFDIDYLKDQVDSLLTPVVLANMEDVKYLDKAQGSVTAG
KDVIFTVQL

Sequences:

>Translated_169_residues
MGFLSRIRRLVSGQTQLAGGIMVYAPVSGDIVAIEKVPDVVFAEKIVGDGIAIAPKGELILAPIDGTIGKIFETNHAFSI
ESPQGLELFVHFGVGTVELRGKGFKRLAQEGQEVKVGDPILSFDIDYLKDQVDSLLTPVVLANMEDVKYLDKAQGSVTAG
KDVIFTVQL
>Mature_168_residues
GFLSRIRRLVSGQTQLAGGIMVYAPVSGDIVAIEKVPDVVFAEKIVGDGIAIAPKGELILAPIDGTIGKIFETNHAFSIE
SPQGLELFVHFGVGTVELRGKGFKRLAQEGQEVKVGDPILSFDIDYLKDQVDSLLTPVVLANMEDVKYLDKAQGSVTAGK
DVIFTVQL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788757, Length=168, Percent_Identity=58.9285714285714, Blast_Score=204, Evalue=3e-54,
Organism=Escherichia coli, GI1786894, Length=145, Percent_Identity=47.5862068965517, Blast_Score=151, Evalue=2e-38,
Organism=Escherichia coli, GI1790159, Length=147, Percent_Identity=36.734693877551, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: 3540 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR001127 [H]

Pfam domain/function: PF00358 PTS_EIIA_1 [H]

EC number: 2.7.1.69

Molecular weight: Translated: 18128; Mature: 17997

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFLSRIRRLVSGQTQLAGGIMVYAPVSGDIVAIEKVPDVVFAEKIVGDGIAIAPKGELI
CCHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHCCCEEECCCCCEE
LAPIDGTIGKIFETNHAFSIESPQGLELFVHFGVGTVELRGKGFKRLAQEGQEVKVGDPI
EEECCCCCCCEEECCCEEEECCCCCEEEEEEECCCEEEECCCCHHHHHHCCCEEECCCCE
LSFDIDYLKDQVDSLLTPVVLANMEDVKYLDKAQGSVTAGKDVIFTVQL
EECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECCCEEEEEEEC
>Mature Secondary Structure 
GFLSRIRRLVSGQTQLAGGIMVYAPVSGDIVAIEKVPDVVFAEKIVGDGIAIAPKGELI
CHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHCCCEEECCCCCEE
LAPIDGTIGKIFETNHAFSIESPQGLELFVHFGVGTVELRGKGFKRLAQEGQEVKVGDPI
EEECCCCCCCEEECCCEEEECCCCCEEEEEEECCCEEEECCCCHHHHHHCCCEEECCCCE
LSFDIDYLKDQVDSLLTPVVLANMEDVKYLDKAQGSVTAGKDVIFTVQL
EECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]