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The map label for this gene is tagD [H]

Identifier: 126174534

GI number: 126174534

Start: 2704324

End: 2704755

Strand: Reverse

Name: tagD [H]

Synonym: Sbal_2321

Alternate gene names: 126174534

Gene position: 2704755-2704324 (Counterclockwise)

Preceding gene: 126174535

Following gene: 126174533

Centisome position: 52.75

GC content: 36.34

Gene sequence:

>432_bases
ATGAAATCAATCATCACTTATGGTACCTATGATCTGTTCCACTATGGTCATGTGAGATTATTTCAAAGACTCAAAGCGAT
GGGAGATAAACTTATTGTTGGTGTATCAACAGATGAGTTTAATTCTCTCAAAGGAAAAGTGGCTTTTTTTAATTACCAGC
AACGTATAGAGATGATAAGTGCCTGTAAATATGTAGATTTAGTGATACCTGAAACTCACTGGCAGCAAAAAGCTAAAGAT
ATTGTAGAACTCAATGTGAATATCTTTGGTATGGGTTCTGATTGGCAGGGGAAATTTGATTATTTAAAAGAGTTTTGCCA
AGTGATTTATTTGGAAAGAACAGATGCTATTTCAACCACTGAAATCAAAACCAACTTGGCAGTCCCTCGCTCAAACAGCA
TCAGATTGCCATCCTCCGCCTTGATTAAGTGA

Upstream 100 bases:

>100_bases
GTCAACTATTAAAACAAAATTCTAGGGCTGTACATTCAGCCTTGGGTACACAATCAATACAAGCCCATATTGACTCTCAC
TCAAGCAAGAGGAATTAATC

Downstream 100 bases:

>100_bases
GGTTCATCATGAAAACAAACTTATTTACTTCATTATTAAAGAAATGTATTTATGGTCTTTCATGGTTTTTTCCGCGACAA
GGAAATAAAGCTGTATTTGG

Product: cytidyltransferase-like protein

Products: NA

Alternate protein names: GCT; Gro-PCT; CDP-glycerol pyrophosphorylase; Teichoic acid biosynthesis protein D [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MKSIITYGTYDLFHYGHVRLFQRLKAMGDKLIVGVSTDEFNSLKGKVAFFNYQQRIEMISACKYVDLVIPETHWQQKAKD
IVELNVNIFGMGSDWQGKFDYLKEFCQVIYLERTDAISTTEIKTNLAVPRSNSIRLPSSALIK

Sequences:

>Translated_143_residues
MKSIITYGTYDLFHYGHVRLFQRLKAMGDKLIVGVSTDEFNSLKGKVAFFNYQQRIEMISACKYVDLVIPETHWQQKAKD
IVELNVNIFGMGSDWQGKFDYLKEFCQVIYLERTDAISTTEIKTNLAVPRSNSIRLPSSALIK
>Mature_143_residues
MKSIITYGTYDLFHYGHVRLFQRLKAMGDKLIVGVSTDEFNSLKGKVAFFNYQQRIEMISACKYVDLVIPETHWQQKAKD
IVELNVNIFGMGSDWQGKFDYLKEFCQVIYLERTDAISTTEIKTNLAVPRSNSIRLPSSALIK

Specific function: Provides activated glycerol phosphate for teichoic acid synthesis, via incorporation into both the linkage unit and the teichoic acid polymer by TagB and TagF [H]

COG id: COG0615

COG function: function code MI; Cytidylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI296841136, Length=121, Percent_Identity=30.5785123966942, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI4505651, Length=121, Percent_Identity=30.5785123966942, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR006409
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.39 [H]

Molecular weight: Translated: 16479; Mature: 16479

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIITYGTYDLFHYGHVRLFQRLKAMGDKLIVGVSTDEFNSLKGKVAFFNYQQRIEMIS
CCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHH
ACKYVDLVIPETHWQQKAKDIVELNVNIFGMGSDWQGKFDYLKEFCQVIYLERTDAISTT
HHHHEEEECCCHHHHHHHHHEEEECEEEEEECCCCCCCHHHHHHHHHHEEHCCCCCCEEE
EIKTNLAVPRSNSIRLPSSALIK
EEEEEECCCCCCCEECCHHHHCC
>Mature Secondary Structure
MKSIITYGTYDLFHYGHVRLFQRLKAMGDKLIVGVSTDEFNSLKGKVAFFNYQQRIEMIS
CCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHH
ACKYVDLVIPETHWQQKAKDIVELNVNIFGMGSDWQGKFDYLKEFCQVIYLERTDAISTT
HHHHEEEECCCHHHHHHHHHEEEECEEEEEECCCCCCCHHHHHHHHHHEEHCCCCCCEEE
EIKTNLAVPRSNSIRLPSSALIK
EEEEEECCCCCCCEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 8393871; 9384377; 9182537; 11487587; 10508782 [H]