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The map label for this gene is cvrA [H]

Identifier: 126174523

GI number: 126174523

Start: 2687660

End: 2689642

Strand: Reverse

Name: cvrA [H]

Synonym: Sbal_2308

Alternate gene names: 126174523

Gene position: 2689642-2687660 (Counterclockwise)

Preceding gene: 126174527

Following gene: 126174522

Centisome position: 52.46

GC content: 46.44

Gene sequence:

>1983_bases
ATGGTTGAACAAATCACGGGTATGTTAGCGCTGATTGGGGTGTTATCGCTTTTTTGTCAATGGCTTGGTTGGAAATTGCG
GTTACCGGCGATTTTGCCCTTACTGCTCTGTGGACTCACCCTCGGCCCCGGACTTGGCTTCCTCAATCCCGATGCTATTT
TTGGCAATTTACTCTTTCCGATCATTTCTCTCGGGGTTGCCGTGATTTTGTTTGAAGGCGCATTGACTCTCAACTTTAAA
GAAATCAAAGATCATGGCCGTATGGTGACGCATCTTGTGACCATAGGGACAGTGATCACTTGGGCTTGTATCAGCACGGC
CACCTTTTATTTACTCGATTTTAGTTGGGAAATTGCACTCCTCTTTGGTGCATTAGTGGTGGTCACGGGACCGACGGTTA
TCGTGCCTATGCTCAGAAGTGTGCGCCCAAAATCCCAATTGGCGAGTATTTTACGCTGGGAAGGCATAGTCATTGACCCC
ATAGGCGCGCTGCTCGCAGTATTAGTTTTTGAATATATTACAGTTTCAGGCGATCAGACAACGCATGTGCTTTATGCCCT
AGGTTCAATGCTTTCTCTAGGATTAGGGCTTGGAGCGGCAGCAGGTTACCTCACTGGGCAAATATTAAGACGCAACCTGT
TGCCACATTATTTGCGCAATACCGCAGTCTTAACCTTAATGCTCGGCATCTTTGTCGGTTCGAACCTATTACAGGAAGAG
TCGGGTCTACTGACTGTGACCGTTATGGGCATTTGGCTTGCCAATATGCGCGGTGTGGATATTGCTGAAATCCTTGAGTT
TAAAGAGACCTTAACCGTACTACTGATTTCGGCATTGTTTATTTTATTGGCGGCGCGATTAGATTCTAATGCCATGCTCG
ACTTAGGTTGGGGCGGACTAGGCGTTTTAGCGGTCACTATGTTGTTAGCTCGGCCGCTGAGTATTTGGGTTTCTGGTGTC
GGCACCTCTTTGTCGAGGGCCGATAAATGGTTTTTATGCTGGATTGCGCCGCGAGGCATAGTCGCTGCGGCGGTATCGTC
ATTGTTTGCGATTAAGTTAGAAGCCAACAATGTGCAAGGCGCCGATGCGATTGTGCCCTTAGTGTTTTTAATTATTATCG
GCACGGTCGTTATCCAAAGTTTAACCGCGGGACGTTGGGCGCGTTTCCTCGGTGTCAAAGCCGATTCTGCCCAAGGTTTA
TTGATTTTCGGTGCTTCTAAATTTTCCCGTGAGTTAGCGAAAATCTTAAAAGCCAAGGATGTCAAAGTGCTATTGGCTGA
TAATAACTGGGATAATATTCGCCTAGCACGTATGGATAATATCCCGGTGTATTTTGGCAATCCCGCATCTGAACATGCTG
AAACCTATATGGATTTAACTGGGATTGGCCTCGTGTTGATCATTTCGCCTTATCGACAATTAAACCCTCTAGTGAGTTTC
CATTTTCAAGATTTCTTTGGCACTAAGAAGGTCTTTGGCTTAAATAATACCGAAGTGGGCAGTGCGCGCCACCAGCTCTC
TGAAACTTATAAGCAGCGCTTATGTCTGTTTGGTGATGCCGTGTCCTATGCCAAGATTGCAAGCCTGATGGCGAGAGGCG
CTCAACTTAAAGTGACCAATTTAACCGAAAACTTCAGCTTTGAGCATTTCCGTAAGCGTTACGGTGAAACGGCTATGCCA
TTGGTTTATTTAACCAAGGAAGGTAAGGTCGTCGTAGTATCAGGTAATGATACTGTGTTCCCGAATGGTATTGAGCTGAT
TAGCTTGTTGCCGATTGAAGCCTTAGAAGAAGCCAAAGTACAGCAAGCGATTGCAGAGCGAGAAGCACAGGAAGCCCAAG
AGAAATCCGCCGCAGAAGCCGCTTTAGCAAAGGCAAAAGCGGAAGAGGAGGCTGAGCAATTAAGGCTTGAGAAATCAGAC
GCTAACGCTGTAATAAATGACGAAGCTGACAAGGGTGTGGTGGATAACATGATAAAGAGTTAA

Upstream 100 bases:

>100_bases
TAAGCGAAATAGATAATTCCCGAGCCATTATCATGCTCATGTCATCTATTTCATTAAAGATAATGCGAGCTCATTGTTTT
TCTCACCTAAAGGATTTTTT

Downstream 100 bases:

>100_bases
CTTGAGCATGTCATAAGGTATCACAGCCATGTTTTATCTTGTTGATACGACAAACTCACTCTCATATTCGCAAGTTAAAC
TGGAGAATACCGATGTTGAA

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MVEQITGMLALIGVLSLFCQWLGWKLRLPAILPLLLCGLTLGPGLGFLNPDAIFGNLLFPIISLGVAVILFEGALTLNFK
EIKDHGRMVTHLVTIGTVITWACISTATFYLLDFSWEIALLFGALVVVTGPTVIVPMLRSVRPKSQLASILRWEGIVIDP
IGALLAVLVFEYITVSGDQTTHVLYALGSMLSLGLGLGAAAGYLTGQILRRNLLPHYLRNTAVLTLMLGIFVGSNLLQEE
SGLLTVTVMGIWLANMRGVDIAEILEFKETLTVLLISALFILLAARLDSNAMLDLGWGGLGVLAVTMLLARPLSIWVSGV
GTSLSRADKWFLCWIAPRGIVAAAVSSLFAIKLEANNVQGADAIVPLVFLIIIGTVVIQSLTAGRWARFLGVKADSAQGL
LIFGASKFSRELAKILKAKDVKVLLADNNWDNIRLARMDNIPVYFGNPASEHAETYMDLTGIGLVLIISPYRQLNPLVSF
HFQDFFGTKKVFGLNNTEVGSARHQLSETYKQRLCLFGDAVSYAKIASLMARGAQLKVTNLTENFSFEHFRKRYGETAMP
LVYLTKEGKVVVVSGNDTVFPNGIELISLLPIEALEEAKVQQAIAEREAQEAQEKSAAEAALAKAKAEEEAEQLRLEKSD
ANAVINDEADKGVVDNMIKS

Sequences:

>Translated_660_residues
MVEQITGMLALIGVLSLFCQWLGWKLRLPAILPLLLCGLTLGPGLGFLNPDAIFGNLLFPIISLGVAVILFEGALTLNFK
EIKDHGRMVTHLVTIGTVITWACISTATFYLLDFSWEIALLFGALVVVTGPTVIVPMLRSVRPKSQLASILRWEGIVIDP
IGALLAVLVFEYITVSGDQTTHVLYALGSMLSLGLGLGAAAGYLTGQILRRNLLPHYLRNTAVLTLMLGIFVGSNLLQEE
SGLLTVTVMGIWLANMRGVDIAEILEFKETLTVLLISALFILLAARLDSNAMLDLGWGGLGVLAVTMLLARPLSIWVSGV
GTSLSRADKWFLCWIAPRGIVAAAVSSLFAIKLEANNVQGADAIVPLVFLIIIGTVVIQSLTAGRWARFLGVKADSAQGL
LIFGASKFSRELAKILKAKDVKVLLADNNWDNIRLARMDNIPVYFGNPASEHAETYMDLTGIGLVLIISPYRQLNPLVSF
HFQDFFGTKKVFGLNNTEVGSARHQLSETYKQRLCLFGDAVSYAKIASLMARGAQLKVTNLTENFSFEHFRKRYGETAMP
LVYLTKEGKVVVVSGNDTVFPNGIELISLLPIEALEEAKVQQAIAEREAQEAQEKSAAEAALAKAKAEEEAEQLRLEKSD
ANAVINDEADKGVVDNMIKS
>Mature_660_residues
MVEQITGMLALIGVLSLFCQWLGWKLRLPAILPLLLCGLTLGPGLGFLNPDAIFGNLLFPIISLGVAVILFEGALTLNFK
EIKDHGRMVTHLVTIGTVITWACISTATFYLLDFSWEIALLFGALVVVTGPTVIVPMLRSVRPKSQLASILRWEGIVIDP
IGALLAVLVFEYITVSGDQTTHVLYALGSMLSLGLGLGAAAGYLTGQILRRNLLPHYLRNTAVLTLMLGIFVGSNLLQEE
SGLLTVTVMGIWLANMRGVDIAEILEFKETLTVLLISALFILLAARLDSNAMLDLGWGGLGVLAVTMLLARPLSIWVSGV
GTSLSRADKWFLCWIAPRGIVAAAVSSLFAIKLEANNVQGADAIVPLVFLIIIGTVVIQSLTAGRWARFLGVKADSAQGL
LIFGASKFSRELAKILKAKDVKVLLADNNWDNIRLARMDNIPVYFGNPASEHAETYMDLTGIGLVLIISPYRQLNPLVSF
HFQDFFGTKKVFGLNNTEVGSARHQLSETYKQRLCLFGDAVSYAKIASLMARGAQLKVTNLTENFSFEHFRKRYGETAMP
LVYLTKEGKVVVVSGNDTVFPNGIELISLLPIEALEEAKVQQAIAEREAQEAQEKSAAEAALAKAKAEEEAEQLRLEKSD
ANAVINDEADKGVVDNMIKS

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 71667; Mature: 71667

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEQITGMLALIGVLSLFCQWLGWKLRLPAILPLLLCGLTLGPGLGFLNPDAIFGNLLFP
CHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
IISLGVAVILFEGALTLNFKEIKDHGRMVTHLVTIGTVITWACISTATFYLLDFSWEIAL
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHH
LFGALVVVTGPTVIVPMLRSVRPKSQLASILRWEGIVIDPIGALLAVLVFEYITVSGDQT
HHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCCCH
THVLYALGSMLSLGLGLGAAAGYLTGQILRRNLLPHYLRNTAVLTLMLGIFVGSNLLQEE
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
SGLLTVTVMGIWLANMRGVDIAEILEFKETLTVLLISALFILLAARLDSNAMLDLGWGGL
CCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
GVLAVTMLLARPLSIWVSGVGTSLSRADKWFLCWIAPRGIVAAAVSSLFAIKLEANNVQG
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEECCCHHHHHHHHHHEEEEEECCCCCC
ADAIVPLVFLIIIGTVVIQSLTAGRWARFLGVKADSAQGLLIFGASKFSRELAKILKAKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHCCCC
VKVLLADNNWDNIRLARMDNIPVYFGNPASEHAETYMDLTGIGLVLIISPYRQLNPLVSF
EEEEEECCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHCCCEEEEECCHHHHCHHHHH
HFQDFFGTKKVFGLNNTEVGSARHQLSETYKQRLCLFGDAVSYAKIASLMARGAQLKVTN
HHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEC
LTENFSFEHFRKRYGETAMPLVYLTKEGKVVVVSGNDTVFPNGIELISLLPIEALEEAKV
CCCCCCHHHHHHHCCCCCCCEEEEECCCEEEEECCCCEECCCCHHHHHHCCHHHHHHHHH
QQAIAEREAQEAQEKSAAEAALAKAKAEEEAEQLRLEKSDANAVINDEADKGVVDNMIKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHCC
>Mature Secondary Structure
MVEQITGMLALIGVLSLFCQWLGWKLRLPAILPLLLCGLTLGPGLGFLNPDAIFGNLLFP
CHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
IISLGVAVILFEGALTLNFKEIKDHGRMVTHLVTIGTVITWACISTATFYLLDFSWEIAL
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHH
LFGALVVVTGPTVIVPMLRSVRPKSQLASILRWEGIVIDPIGALLAVLVFEYITVSGDQT
HHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCCCH
THVLYALGSMLSLGLGLGAAAGYLTGQILRRNLLPHYLRNTAVLTLMLGIFVGSNLLQEE
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
SGLLTVTVMGIWLANMRGVDIAEILEFKETLTVLLISALFILLAARLDSNAMLDLGWGGL
CCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
GVLAVTMLLARPLSIWVSGVGTSLSRADKWFLCWIAPRGIVAAAVSSLFAIKLEANNVQG
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEECCCHHHHHHHHHHEEEEEECCCCCC
ADAIVPLVFLIIIGTVVIQSLTAGRWARFLGVKADSAQGLLIFGASKFSRELAKILKAKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHCCCC
VKVLLADNNWDNIRLARMDNIPVYFGNPASEHAETYMDLTGIGLVLIISPYRQLNPLVSF
EEEEEECCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHCCCEEEEECCHHHHCHHHHH
HFQDFFGTKKVFGLNNTEVGSARHQLSETYKQRLCLFGDAVSYAKIASLMARGAQLKVTN
HHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEC
LTENFSFEHFRKRYGETAMPLVYLTKEGKVVVVSGNDTVFPNGIELISLLPIEALEEAKV
CCCCCCHHHHHHHCCCCCCCEEEEECCCEEEEECCCCEECCCCHHHHHHCCHHHHHHHHH
QQAIAEREAQEAQEKSAAEAALAKAKAEEEAEQLRLEKSDANAVINDEADKGVVDNMIKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]