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The map label for this gene is rsmB [H]

Identifier: 126174501

GI number: 126174501

Start: 2653617

End: 2654831

Strand: Reverse

Name: rsmB [H]

Synonym: Sbal_2285

Alternate gene names: 126174501

Gene position: 2654831-2653617 (Counterclockwise)

Preceding gene: 126174502

Following gene: 126174500

Centisome position: 51.78

GC content: 50.7

Gene sequence:

>1215_bases
ATGTTGAATTCTCCGCTTTCTGCCAGCTCGAACGAATTAGTGATCAGTATCTTAACTATGGTGCTGAGCCAAGGAAAACC
CTTAGATCGGGCCTATTCTCAGCATTTTTCTGGGTTGCAATTGGTACCCGCCGAACAGGCGCGTATCGCATTAACGACGG
GTGATATCCTACGTCGTTTAAATTTATATTGTTATCTGGCGGAAATCAGTCCAGATGAGATGGAGCGTTTCGGCTCTAAA
TTGCTTAATGCGTGGCATTTATTCCACGGGCTTGAACTGCCTAAAATGCAATATTCGCTGCAAGTCGATGAGGCGCGTTT
AGCCGAGCGCACCGAGCAAGCGAAAACTAAGCCAGTACTGTGGGACGGTTGCCCTGAGTGGCTCGATGCGATGGGCCGTG
AGCAATTAGGCGAGTCTTGGGAAAAGGAGCGCGCCGCGTTAAGCACAGCGCCGAAGCGTTTTTTACGCGCAAATGGCCTT
AAAGTGACGCGTGAGGAATTGGCCGCTAAGCTTGCCGCTGAGTTTGTGAGCACGCTGAGCGTTGATGGGGTCGATTCTGC
CCTTGAAGTGACCTCCGATTCTGCCTTGTTCCGTACCCAAAGCTTTAAAGATGGCTTATTCGAGCAGCAAGATGCGGGCT
CTCAGCGCGTGGCGGCGGCGCTTGATGCCAAGCCAGGCATGAAAGTTATTGATGCTTGCGCAGGCGCGGGTGGCAAAACC
TTACACATAGCCGCGCAAATGCAGGGCAAAGGGCGCTTGTTGGCCATGGATGTGGAGCAATGGAAACTCGACAAACTCAA
AGAGCGTGCCCGTCGCAATGGCGCGCACAATGTCGAAACCCGCGTGATTGCCAGCAGTAAAACCATTAAACGCTTAAAGC
TCAGCGCCGATCGGGTATTACTCGATGTGCCATGCTCAGGTTTGGGCGTATTAAAGCGTAATCCAGATGCAAAATGGCGC
GATACTGTTGAGCGTTTACCTGTGTTAATGGAGTTGCAAAAGCACATTTTGACCAGCTACAGCCGCATGGTGAAGGTTGG
CGGCATAGTGGTTTATGCGACCTGTTCTATCTTCCCCTGCGAGAACCGTGGTCAAGTCGATGCGTTTTTAGCCGAGAATC
CTAATTTCCGCCTGATTGAGGATGAAAGTATCAGCCCAGCCGATAGCGGATTTGATGGTTTTTACCTTGCAAAACTTGAA
CGTATTCAAGAATAA

Upstream 100 bases:

>100_bases
TTTTTTATGGCTTTAACCTTAACTCAGCGCCAGCGTGCTTGCGTATTAGGGCCTGACCTCCTATGATCCTCCGGTTTTAT
CATTCATGGTGACCTTTTAA

Downstream 100 bases:

>100_bases
AGCCTTGCCGTTAAGACTAAAGTAAGCCCTTTATTGAATTGATACAGGGTTTACTTAGTTAACATTAGTGCCTAGAATTT
CCTATAAGTTATAAATATTT

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MLNSPLSASSNELVISILTMVLSQGKPLDRAYSQHFSGLQLVPAEQARIALTTGDILRRLNLYCYLAEISPDEMERFGSK
LLNAWHLFHGLELPKMQYSLQVDEARLAERTEQAKTKPVLWDGCPEWLDAMGREQLGESWEKERAALSTAPKRFLRANGL
KVTREELAAKLAAEFVSTLSVDGVDSALEVTSDSALFRTQSFKDGLFEQQDAGSQRVAAALDAKPGMKVIDACAGAGGKT
LHIAAQMQGKGRLLAMDVEQWKLDKLKERARRNGAHNVETRVIASSKTIKRLKLSADRVLLDVPCSGLGVLKRNPDAKWR
DTVERLPVLMELQKHILTSYSRMVKVGGIVVYATCSIFPCENRGQVDAFLAENPNFRLIEDESISPADSGFDGFYLAKLE
RIQE

Sequences:

>Translated_404_residues
MLNSPLSASSNELVISILTMVLSQGKPLDRAYSQHFSGLQLVPAEQARIALTTGDILRRLNLYCYLAEISPDEMERFGSK
LLNAWHLFHGLELPKMQYSLQVDEARLAERTEQAKTKPVLWDGCPEWLDAMGREQLGESWEKERAALSTAPKRFLRANGL
KVTREELAAKLAAEFVSTLSVDGVDSALEVTSDSALFRTQSFKDGLFEQQDAGSQRVAAALDAKPGMKVIDACAGAGGKT
LHIAAQMQGKGRLLAMDVEQWKLDKLKERARRNGAHNVETRVIASSKTIKRLKLSADRVLLDVPCSGLGVLKRNPDAKWR
DTVERLPVLMELQKHILTSYSRMVKVGGIVVYATCSIFPCENRGQVDAFLAENPNFRLIEDESISPADSGFDGFYLAKLE
RIQE
>Mature_404_residues
MLNSPLSASSNELVISILTMVLSQGKPLDRAYSQHFSGLQLVPAEQARIALTTGDILRRLNLYCYLAEISPDEMERFGSK
LLNAWHLFHGLELPKMQYSLQVDEARLAERTEQAKTKPVLWDGCPEWLDAMGREQLGESWEKERAALSTAPKRFLRANGL
KVTREELAAKLAAEFVSTLSVDGVDSALEVTSDSALFRTQSFKDGLFEQQDAGSQRVAAALDAKPGMKVIDACAGAGGKT
LHIAAQMQGKGRLLAMDVEQWKLDKLKERARRNGAHNVETRVIASSKTIKRLKLSADRVLLDVPCSGLGVLKRNPDAKWR
DTVERLPVLMELQKHILTSYSRMVKVGGIVVYATCSIFPCENRGQVDAFLAENPNFRLIEDESISPADSGFDGFYLAKLE
RIQE

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=185, Percent_Identity=32.972972972973, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI76150625, Length=280, Percent_Identity=28.2142857142857, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI76150623, Length=280, Percent_Identity=28.2142857142857, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI270288816, Length=233, Percent_Identity=30.9012875536481, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI8922322, Length=233, Percent_Identity=30.9012875536481, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI270288818, Length=233, Percent_Identity=30.9012875536481, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI23199998, Length=233, Percent_Identity=30.9012875536481, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI301336155, Length=192, Percent_Identity=29.1666666666667, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI39995082, Length=192, Percent_Identity=29.1666666666667, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI2367212, Length=283, Percent_Identity=29.6819787985866, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87081985, Length=218, Percent_Identity=28.8990825688073, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17536757, Length=289, Percent_Identity=29.4117647058824, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI115534021, Length=170, Percent_Identity=31.1764705882353, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71998419, Length=249, Percent_Identity=27.710843373494, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324268, Length=280, Percent_Identity=27.1428571428571, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319447, Length=179, Percent_Identity=28.4916201117318, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355201, Length=196, Percent_Identity=30.6122448979592, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI22024126, Length=281, Percent_Identity=26.6903914590747, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19920494, Length=165, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 44820; Mature: 44820

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSPLSASSNELVISILTMVLSQGKPLDRAYSQHFSGLQLVPAEQARIALTTGDILRRL
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCEEEEEHHHHHHHH
NLYCYLAEISPDEMERFGSKLLNAWHLFHGLELPKMQYSLQVDEARLAERTEQAKTKPVL
HHEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHCCCCCE
WDGCPEWLDAMGREQLGESWEKERAALSTAPKRFLRANGLKVTREELAAKLAAEFVSTLS
ECCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHC
VDGVDSALEVTSDSALFRTQSFKDGLFEQQDAGSQRVAAALDAKPGMKVIDACAGAGGKT
CCCCCHHHHHCCCCHHHHHCCHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCE
LHIAAQMQGKGRLLAMDVEQWKLDKLKERARRNGAHNVETRVIASSKTIKRLKLSADRVL
EEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCEEE
LDVPCSGLGVLKRNPDAKWRDTVERLPVLMELQKHILTSYSRMVKVGGIVVYATCSIFPC
EECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEC
ENRGQVDAFLAENPNFRLIEDESISPADSGFDGFYLAKLERIQE
CCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLNSPLSASSNELVISILTMVLSQGKPLDRAYSQHFSGLQLVPAEQARIALTTGDILRRL
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCEEEEEHHHHHHHH
NLYCYLAEISPDEMERFGSKLLNAWHLFHGLELPKMQYSLQVDEARLAERTEQAKTKPVL
HHEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHCCCCCE
WDGCPEWLDAMGREQLGESWEKERAALSTAPKRFLRANGLKVTREELAAKLAAEFVSTLS
ECCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHC
VDGVDSALEVTSDSALFRTQSFKDGLFEQQDAGSQRVAAALDAKPGMKVIDACAGAGGKT
CCCCCHHHHHCCCCHHHHHCCHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCE
LHIAAQMQGKGRLLAMDVEQWKLDKLKERARRNGAHNVETRVIASSKTIKRLKLSADRVL
EEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCEEE
LDVPCSGLGVLKRNPDAKWRDTVERLPVLMELQKHILTSYSRMVKVGGIVVYATCSIFPC
EECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEC
ENRGQVDAFLAENPNFRLIEDESISPADSGFDGFYLAKLERIQE
CCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]