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The map label for this gene is aspC [H]

Identifier: 126174431

GI number: 126174431

Start: 2560613

End: 2561806

Strand: Reverse

Name: aspC [H]

Synonym: Sbal_2215

Alternate gene names: 126174431

Gene position: 2561806-2560613 (Counterclockwise)

Preceding gene: 126174432

Following gene: 126174429

Centisome position: 49.96

GC content: 47.49

Gene sequence:

>1194_bases
ATGATTTTCTCTCAGGTATTACTCGCACCCGCTGATCCGATTCTTGGTTTAACCGATACCTTTAAGGCTGATCCCCGTCA
GGATAAAGTCAATTTGGGTGTCGGTATTTATAAGGATGAGGCTGGACAAACCCCTGTGCTGGCTTCAGTGAAAAAAGCCG
AGGCTATTTTACTTGAGCAAGAGAAGACCAAAAACTACTTAGGCATTGAAGGCGTGCAAGCGTATAACCATGTTGTGCAA
ACATTGTTATTCGGTGAGGGTAGCGAGTTAATCACTTCTGGCCGTGCTGCCACAGCGCAAGCACCTGGTGGTACAGGTGC
ACTGCGTATTGCTGCTGAGTTTTTACTGCGTAATACCGATTCGCACACTATTTGGGTCAGCAATCCAACGTGGGCCAACC
ATCAGAATATTTTTGAAACCGCGGGTTTAACCGTTAAAGAGTACGGTTATTACAAAGCAGAAGCCCATGATATCGATTTT
GATACCATGATGACGGACTTGTCTCACGCGAGTGCAGGCGATGTCGTGTTGCTACACGGTTGCAGCCATAACCCAACAGG
CATCGATTTAACCTTGGCGCAATGGGAACTCGTAGCCCAATTGTGTGCCGATAAGAAACTTGTGCCACTGTTTGACTTTG
CATACCAAGGTTTTGGTGCTGGAATTGAAGAAGATGCCGCAGGTCTGCGTTTAGTGGCATCAAAAGTGCCTGAGCTGCTG
GTTGCTAACTCTTTCTCTAAAAACTTTGGTTTGTACAACGAACGTATCGGCGCCGTAACTGTGGTGGCTGAAGATGCTGA
TGCTGCCGTGCGTGCCTTTAGCCAAGTGAAACGTACCATACGTGCAAACTATTCTAACCCGCCAGCACATGGCGCGCTGA
TCGTCAGCACTATCTTGAATGATGCAGCCCTGAAAGCCATGTGGGTGCAGGAAGTTAAAGAGATGCGTGAGCGTATCGCC
GAAATGCGCACTTTGTTCGTTGACAGCTTAAAGGCTGAAGGCGTGACTCAGGACTTTAGCTTTATTTCTCGCCAAAATGG
TATGTTCAGTTTCTCTGGTTTGAACAAAGCCCAAGTGGCGCGCTTGAAAGACGAGTTTGGGGTTTATATCGTTGGTTCAG
GACGCATTAGCGTTGCAGGCATGACTAAGACCAATATGCCAGTGATCAGTAAAGCTATCGCCAGAGTCTTGTAA

Upstream 100 bases:

>100_bases
ATTTCCCTAAGAAGGTGCTTAAGTAGCTATTACCCCCTTAAAGACAGTGGTATAAATAAGCCGAAATTTCCCCTACACGC
GCATATTAGGATACGTAGTC

Downstream 100 bases:

>100_bases
GGCTTATTAGGTTATAGAATGTGGCTAAAGGAATTTCTCTTTAGCCTTCAAACATAAAGGACAGCATTTGCTGTCCTTTA
TGTTTTTATTGTGTCAGCAC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MIFSQVLLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLASVKKAEAILLEQEKTKNYLGIEGVQAYNHVVQ
TLLFGEGSELITSGRAATAQAPGGTGALRIAAEFLLRNTDSHTIWVSNPTWANHQNIFETAGLTVKEYGYYKAEAHDIDF
DTMMTDLSHASAGDVVLLHGCSHNPTGIDLTLAQWELVAQLCADKKLVPLFDFAYQGFGAGIEEDAAGLRLVASKVPELL
VANSFSKNFGLYNERIGAVTVVAEDADAAVRAFSQVKRTIRANYSNPPAHGALIVSTILNDAALKAMWVQEVKEMRERIA
EMRTLFVDSLKAEGVTQDFSFISRQNGMFSFSGLNKAQVARLKDEFGVYIVGSGRISVAGMTKTNMPVISKAIARVL

Sequences:

>Translated_397_residues
MIFSQVLLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLASVKKAEAILLEQEKTKNYLGIEGVQAYNHVVQ
TLLFGEGSELITSGRAATAQAPGGTGALRIAAEFLLRNTDSHTIWVSNPTWANHQNIFETAGLTVKEYGYYKAEAHDIDF
DTMMTDLSHASAGDVVLLHGCSHNPTGIDLTLAQWELVAQLCADKKLVPLFDFAYQGFGAGIEEDAAGLRLVASKVPELL
VANSFSKNFGLYNERIGAVTVVAEDADAAVRAFSQVKRTIRANYSNPPAHGALIVSTILNDAALKAMWVQEVKEMRERIA
EMRTLFVDSLKAEGVTQDFSFISRQNGMFSFSGLNKAQVARLKDEFGVYIVGSGRISVAGMTKTNMPVISKAIARVL
>Mature_397_residues
MIFSQVLLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLASVKKAEAILLEQEKTKNYLGIEGVQAYNHVVQ
TLLFGEGSELITSGRAATAQAPGGTGALRIAAEFLLRNTDSHTIWVSNPTWANHQNIFETAGLTVKEYGYYKAEAHDIDF
DTMMTDLSHASAGDVVLLHGCSHNPTGIDLTLAQWELVAQLCADKKLVPLFDFAYQGFGAGIEEDAAGLRLVASKVPELL
VANSFSKNFGLYNERIGAVTVVAEDADAAVRAFSQVKRTIRANYSNPPAHGALIVSTILNDAALKAMWVQEVKEMRERIA
EMRTLFVDSLKAEGVTQDFSFISRQNGMFSFSGLNKAQVARLKDEFGVYIVGSGRISVAGMTKTNMPVISKAIARVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=44.1919191919192, Blast_Score=335, Evalue=6e-92,
Organism=Homo sapiens, GI4504067, Length=400, Percent_Identity=39.75, Blast_Score=295, Evalue=4e-80,
Organism=Homo sapiens, GI117414139, Length=384, Percent_Identity=26.5625, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=61.6161616161616, Blast_Score=527, Evalue=1e-151,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=46.5994962216625, Blast_Score=373, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=43.7974683544304, Blast_Score=355, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=43.0379746835443, Blast_Score=334, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI17569539, Length=395, Percent_Identity=37.7215189873418, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=36.8821292775665, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=30.2325581395349, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=39.8104265402844, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=37.4384236453202, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6322743, Length=431, Percent_Identity=33.8747099767981, Blast_Score=240, Evalue=3e-64,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=41.9191919191919, Blast_Score=323, Evalue=9e-89,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=41.9191919191919, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24654046, Length=395, Percent_Identity=42.2784810126582, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI19922362, Length=395, Percent_Identity=42.2784810126582, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=41.6879795396419, Blast_Score=317, Evalue=7e-87,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43003; Mature: 43003

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSQVLLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLASVKKAEAILLEQ
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEECEEEEECCCCCCCHHHHHHHHHHHEEEH
EKTKNYLGIEGVQAYNHVVQTLLFGEGSELITSGRAATAQAPGGTGALRIAAEFLLRNTD
HHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCC
SHTIWVSNPTWANHQNIFETAGLTVKEYGYYKAEAHDIDFDTMMTDLSHASAGDVVLLHG
CCEEEECCCCCCCCCHHHHHCCCEEECCCCEECCCCCCCHHHHHHHHCCCCCCCEEEEEC
CSHNPTGIDLTLAQWELVAQLCADKKLVPLFDFAYQGFGAGIEEDAAGLRLVASKVPELL
CCCCCCCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHH
VANSFSKNFGLYNERIGAVTVVAEDADAAVRAFSQVKRTIRANYSNPPAHGALIVSTILN
HHCCCHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DAALKAMWVQEVKEMRERIAEMRTLFVDSLKAEGVTQDFSFISRQNGMFSFSGLNKAQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCCHHHHH
RLKDEFGVYIVGSGRISVAGMTKTNMPVISKAIARVL
HHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MIFSQVLLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLASVKKAEAILLEQ
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEECEEEEECCCCCCCHHHHHHHHHHHEEEH
EKTKNYLGIEGVQAYNHVVQTLLFGEGSELITSGRAATAQAPGGTGALRIAAEFLLRNTD
HHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCC
SHTIWVSNPTWANHQNIFETAGLTVKEYGYYKAEAHDIDFDTMMTDLSHASAGDVVLLHG
CCEEEECCCCCCCCCHHHHHCCCEEECCCCEECCCCCCCHHHHHHHHCCCCCCCEEEEEC
CSHNPTGIDLTLAQWELVAQLCADKKLVPLFDFAYQGFGAGIEEDAAGLRLVASKVPELL
CCCCCCCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHH
VANSFSKNFGLYNERIGAVTVVAEDADAAVRAFSQVKRTIRANYSNPPAHGALIVSTILN
HHCCCHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DAALKAMWVQEVKEMRERIAEMRTLFVDSLKAEGVTQDFSFISRQNGMFSFSGLNKAQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCCHHHHH
RLKDEFGVYIVGSGRISVAGMTKTNMPVISKAIARVL
HHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]