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The map label for this gene is trxB [H]

Identifier: 126174369

GI number: 126174369

Start: 2495937

End: 2496890

Strand: Reverse

Name: trxB [H]

Synonym: Sbal_2152

Alternate gene names: 126174369

Gene position: 2496890-2495937 (Counterclockwise)

Preceding gene: 126174371

Following gene: 126174364

Centisome position: 48.7

GC content: 46.86

Gene sequence:

>954_bases
ATGAGCCAGGTCAGACATTGTAACTTATTGATTTTGGGTTCAGGCCCAGCAGGATATACCGCAGCCGTTTATGCTGCGCG
TGCTAATTTAAAACCTGTGATGATCACAGGTATGCAGCAAGGTGGTCAATTAACCACTACGACTGAAGTTGAAAACTGGC
CAGGTGACGCGGATGACTTAACTGGTCCAGCGTTGATGGAACGTATGCAGAAGCATGCTGAAAAGTTTGATACTGAAATC
TTGTTCGATCACATCAACGAAGTGACTCTAACTGAGCGCCCTTTCCGTTTGAAAGGCGATAACGGTGAGTACACCTGTGA
TGCGCTGATCATAGCAACTGGCGCTTCAGCCCGTTACTTAGGATTAGAATCAGAAGAAGCATTCAAGGGCCGTGGCGTAT
CAGCCTGTGCGACCTGTGATGGTTTCTTCTATCGCAATCAAAAAGTCGCAGTGATCGGTGGCGGTAACACTGCAGTTGAA
GAAGCATTGTACTTAAGCAATATTGCCGCTGAAGTGCATCTGATCCATCGTCGTGACACCTTCCGCTCAGAAAAAATTCT
GATCGACCGTCTGATGGACAAAGTTGCCAATGGCAACATCATCCTTCACTTAGATCAAACCATGGATGAAGTGGTTGGTG
ATGCTATGGGTGTAAACGGCCTGAAGATGAAGAGCACTAAAGATGGCTCGATCACTGACTTAGCCGTTGCTGGTGTGTTC
GTCGCCATTGGTCACAGCCCTAATACCGGTATTTTTGAAGGCCAGTTGGAAATGAACCACGGTTATTTAAAAGTACAGAG
CGGTTTGCAAGGTAACGCCACGCAAACCAGTATCGAAGGTGTTTATGCTTGTGGTGATGTGATGGACCAACATTATCGTC
AAGCGATTACTTCTGCGGGCACAGGTTGTATGGCCGCACTCGATGCAGAGCGTTATTTAGACGCTAAAAAGTAA

Upstream 100 bases:

>100_bases
ACTCGATTAGCGCAATCTAAAAGAATCGCCCTTCAACACTTTACCCCTACAGGTAAATTCCCTACAATCCTTGCAATTTG
CTAAAGGCACGGAGATAAAA

Downstream 100 bases:

>100_bases
CTAGACTCGATTTTTCAACGAATAGCAGGCTTAGCCTGCTATTTTTTTAGTCCAAAATCGTTAAGCGATAGCAATTTTTT
TTGCGGGCTTGCCAATCAGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSQVRHCNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEVENWPGDADDLTGPALMERMQKHAEKFDTEI
LFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASARYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIAAEVHLIHRRDTFRSEKILIDRLMDKVANGNIILHLDQTMDEVVGDAMGVNGLKMKSTKDGSITDLAVAGVF
VAIGHSPNTGIFEGQLEMNHGYLKVQSGLQGNATQTSIEGVYACGDVMDQHYRQAITSAGTGCMAALDAERYLDAKK

Sequences:

>Translated_317_residues
MSQVRHCNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEVENWPGDADDLTGPALMERMQKHAEKFDTEI
LFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASARYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIAAEVHLIHRRDTFRSEKILIDRLMDKVANGNIILHLDQTMDEVVGDAMGVNGLKMKSTKDGSITDLAVAGVF
VAIGHSPNTGIFEGQLEMNHGYLKVQSGLQGNATQTSIEGVYACGDVMDQHYRQAITSAGTGCMAALDAERYLDAKK
>Mature_316_residues
SQVRHCNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEVENWPGDADDLTGPALMERMQKHAEKFDTEIL
FDHINEVTLTERPFRLKGDNGEYTCDALIIATGASARYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEE
ALYLSNIAAEVHLIHRRDTFRSEKILIDRLMDKVANGNIILHLDQTMDEVVGDAMGVNGLKMKSTKDGSITDLAVAGVFV
AIGHSPNTGIFEGQLEMNHGYLKVQSGLQGNATQTSIEGVYACGDVMDQHYRQAITSAGTGCMAALDAERYLDAKK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=80, Blast_Score=529, Evalue=1e-152,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=32.6984126984127, Blast_Score=136, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321898, Length=329, Percent_Identity=46.2006079027356, Blast_Score=283, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=45.9375, Blast_Score=275, Evalue=1e-74,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34188; Mature: 34057

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVRHCNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEVENWPGDADDL
CCCCCEEEEEEEECCCCCCHHEEEEHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPALMERMQKHAEKFDTEILFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCCEEEEEEEEEECCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIAAEVHLIHRRDT
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCC
FRSEKILIDRLMDKVANGNIILHLDQTMDEVVGDAMGVNGLKMKSTKDGSITDLAVAGVF
CCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHEEEE
VAIGHSPNTGIFEGQLEMNHGYLKVQSGLQGNATQTSIEGVYACGDVMDQHYRQAITSAG
EEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHCCEEHHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDAKK
CCCEEECCHHHHCCCCC
>Mature Secondary Structure 
SQVRHCNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEVENWPGDADDL
CCCCEEEEEEEECCCCCCHHEEEEHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPALMERMQKHAEKFDTEILFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCCEEEEEEEEEECCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIAAEVHLIHRRDT
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCC
FRSEKILIDRLMDKVANGNIILHLDQTMDEVVGDAMGVNGLKMKSTKDGSITDLAVAGVF
CCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHEEEE
VAIGHSPNTGIFEGQLEMNHGYLKVQSGLQGNATQTSIEGVYACGDVMDQHYRQAITSAG
EEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHCCEEHHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDAKK
CCCEEECCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]