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The map label for this gene is aspC [H]

Identifier: 126174288

GI number: 126174288

Start: 2399249

End: 2400439

Strand: Reverse

Name: aspC [H]

Synonym: Sbal_2067

Alternate gene names: 126174288

Gene position: 2400439-2399249 (Counterclockwise)

Preceding gene: 126174299

Following gene: 126174287

Centisome position: 46.82

GC content: 49.2

Gene sequence:

>1191_bases
ATGTTTAACTCACTCATCGCAATGCCAGCAGATCCCATCCTTGGCTTGTTGACTCAGTACCGCGAAGACACCCACCCACA
AAAAGTTGATTTAGGTGTGGGCGTTTATAAAGACCCTACAGGCGTGACCCCGATCCTGAGCTGCGTGAAAAAAGCCGAGA
AATTCCGTCTCGATACCGAAACCACCAAAGTGTATATCGGTCCAACGGGCTCGCCACAATTCAACACTTTAATGACAGAA
TTAGCCTTTGGTGCAAATCACAGTGCTATTCTCGCCAATCGTATCCGTACCGTTTCTACACCCGGTGGTACTGGCGCACT
GCGCGTGGCCGGCGACTTTATCAAACGCTGCAACCCGAATGCGGTGTTATGGGTAAGCGACCCAACTTGGGCAAACCACA
TCGGTTTGTTCGAAGCGGCTGGCATTACCGTTAAAACCTATCCGTATTATGACTACGATAGCAAATCATTGAAATTTGAT
GAGATGCTTGCTGCCCTATCGCAAGTGAGTCCTGATGATGTGGTGTTATTCCACGCCTGTTGCCATAATCCGAGCGGAAT
GGATTTAACCACAGTGCAATGGGATAAAGTGGTTGCCCTGACAAAAGAGCAAGGCTTTACCCCACTGATTGACATGGCAT
ACCAAGGCTTTGGTGATGGCGTTGATATTGATGCCTACGGCGTGCGTCAAATGGCGGCAGCAGTCGATAATATGATCCTT
TGCAGCTCATGCTCGAAAAACTTCGGTCTGTACCGTGAGCGTATCGGTTCATGCTCTGTGATTGCCAGAGATGCCCATAC
CGCCAATGTCGCGCAGTCTGTGCTGCTTTATGTGGTTCGCTGCCTCTATTCAATGCCGCCTGCCCACGGCGCTGCGATTG
TTGAGACGATTTTAGGTTCGGCAGAATTGACCCAAGAATGGCTAGATGAACTGAAAGTAATGCGCGATCGCATTAACGGC
AACCGTGCCATTTTAGTGGATAAACTTAAAGCCAATGGCGTAGACCGTGACTTTAGCTTTATCGCCCGCCAAAAAGGCAT
GTTCTCCTTCCTCGGGGTGAATCCAGAGCAAGTGGCGCGCCTGCAAAAAGAATTCAGCATTTATATGGTGGGTTCAAGCC
GCATCAGTATTGCTGGGATCAGTGAAGATAACGTCGATTACTTAGCCCAATCGATCGCCAGAGTGCTTTAA

Upstream 100 bases:

>100_bases
ACGTTACCTTTCCGCGCTATTCTAAGCCCCAAACGATAAATAACGCATATCTGATACAAACAATCACGTTTGCACTATAA
CCAGAAAGGTAGATGGAGCT

Downstream 100 bases:

>100_bases
GCACGACTGAGTTTATCTGCACAGCTTACTCTGCTGTATTGCTACGATTCAGGATGCAGCAGAGTTTATTTCCCCCTTAC
AAGCGTTACGCTTTTCAATC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MFNSLIAMPADPILGLLTQYREDTHPQKVDLGVGVYKDPTGVTPILSCVKKAEKFRLDTETTKVYIGPTGSPQFNTLMTE
LAFGANHSAILANRIRTVSTPGGTGALRVAGDFIKRCNPNAVLWVSDPTWANHIGLFEAAGITVKTYPYYDYDSKSLKFD
EMLAALSQVSPDDVVLFHACCHNPSGMDLTTVQWDKVVALTKEQGFTPLIDMAYQGFGDGVDIDAYGVRQMAAAVDNMIL
CSSCSKNFGLYRERIGSCSVIARDAHTANVAQSVLLYVVRCLYSMPPAHGAAIVETILGSAELTQEWLDELKVMRDRING
NRAILVDKLKANGVDRDFSFIARQKGMFSFLGVNPEQVARLQKEFSIYMVGSSRISIAGISEDNVDYLAQSIARVL

Sequences:

>Translated_396_residues
MFNSLIAMPADPILGLLTQYREDTHPQKVDLGVGVYKDPTGVTPILSCVKKAEKFRLDTETTKVYIGPTGSPQFNTLMTE
LAFGANHSAILANRIRTVSTPGGTGALRVAGDFIKRCNPNAVLWVSDPTWANHIGLFEAAGITVKTYPYYDYDSKSLKFD
EMLAALSQVSPDDVVLFHACCHNPSGMDLTTVQWDKVVALTKEQGFTPLIDMAYQGFGDGVDIDAYGVRQMAAAVDNMIL
CSSCSKNFGLYRERIGSCSVIARDAHTANVAQSVLLYVVRCLYSMPPAHGAAIVETILGSAELTQEWLDELKVMRDRING
NRAILVDKLKANGVDRDFSFIARQKGMFSFLGVNPEQVARLQKEFSIYMVGSSRISIAGISEDNVDYLAQSIARVL
>Mature_396_residues
MFNSLIAMPADPILGLLTQYREDTHPQKVDLGVGVYKDPTGVTPILSCVKKAEKFRLDTETTKVYIGPTGSPQFNTLMTE
LAFGANHSAILANRIRTVSTPGGTGALRVAGDFIKRCNPNAVLWVSDPTWANHIGLFEAAGITVKTYPYYDYDSKSLKFD
EMLAALSQVSPDDVVLFHACCHNPSGMDLTTVQWDKVVALTKEQGFTPLIDMAYQGFGDGVDIDAYGVRQMAAAVDNMIL
CSSCSKNFGLYRERIGSCSVIARDAHTANVAQSVLLYVVRCLYSMPPAHGAAIVETILGSAELTQEWLDELKVMRDRING
NRAILVDKLKANGVDRDFSFIARQKGMFSFLGVNPEQVARLQKEFSIYMVGSSRISIAGISEDNVDYLAQSIARVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=390, Percent_Identity=41.025641025641, Blast_Score=304, Evalue=1e-82,
Organism=Homo sapiens, GI4504067, Length=393, Percent_Identity=37.4045801526718, Blast_Score=266, Evalue=3e-71,
Organism=Homo sapiens, GI117414139, Length=385, Percent_Identity=25.974025974026, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=48.4848484848485, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1790488, Length=398, Percent_Identity=39.9497487437186, Blast_Score=323, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=40.5063291139241, Blast_Score=325, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI25147133, Length=390, Percent_Identity=41.5384615384615, Blast_Score=316, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17569539, Length=396, Percent_Identity=34.0909090909091, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17569537, Length=388, Percent_Identity=29.1237113402062, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25147136, Length=206, Percent_Identity=37.8640776699029, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=27.7566539923954, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=35.8024691358025, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6322743, Length=425, Percent_Identity=31.5294117647059, Blast_Score=219, Evalue=6e-58,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=39.1414141414141, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=39.1414141414141, Blast_Score=299, Evalue=3e-81,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=39.5886889460154, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24654046, Length=387, Percent_Identity=39.5348837209302, Blast_Score=287, Evalue=9e-78,
Organism=Drosophila melanogaster, GI19922362, Length=387, Percent_Identity=39.5348837209302, Blast_Score=287, Evalue=9e-78,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43359; Mature: 43359

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNSLIAMPADPILGLLTQYREDTHPQKVDLGVGVYKDPTGVTPILSCVKKAEKFRLDTE
CCCCEECCCCHHHHHHHHHHHHCCCCCEEEECCCEECCCCCCHHHHHHHHHHHHHCCCCC
TTKVYIGPTGSPQFNTLMTELAFGANHSAILANRIRTVSTPGGTGALRVAGDFIKRCNPN
CEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCCEEHHHHHHHHHCCCC
AVLWVSDPTWANHIGLFEAAGITVKTYPYYDYDSKSLKFDEMLAALSQVSPDDVVLFHAC
EEEEECCCCCCHHCCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
CHNPSGMDLTTVQWDKVVALTKEQGFTPLIDMAYQGFGDGVDIDAYGVRQMAAAVDNMIL
CCCCCCCEEEEEEHHHEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCE
CSSCSKNFGLYRERIGSCSVIARDAHTANVAQSVLLYVVRCLYSMPPAHGAAIVETILGS
ECCCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
AELTQEWLDELKVMRDRINGNRAILVDKLKANGVDRDFSFIARQKGMFSFLGVNPEQVAR
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEECCCHHHHHH
LQKEFSIYMVGSSRISIAGISEDNVDYLAQSIARVL
HHHHCEEEEEECCEEEEEECCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MFNSLIAMPADPILGLLTQYREDTHPQKVDLGVGVYKDPTGVTPILSCVKKAEKFRLDTE
CCCCEECCCCHHHHHHHHHHHHCCCCCEEEECCCEECCCCCCHHHHHHHHHHHHHCCCCC
TTKVYIGPTGSPQFNTLMTELAFGANHSAILANRIRTVSTPGGTGALRVAGDFIKRCNPN
CEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCCEEHHHHHHHHHCCCC
AVLWVSDPTWANHIGLFEAAGITVKTYPYYDYDSKSLKFDEMLAALSQVSPDDVVLFHAC
EEEEECCCCCCHHCCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
CHNPSGMDLTTVQWDKVVALTKEQGFTPLIDMAYQGFGDGVDIDAYGVRQMAAAVDNMIL
CCCCCCCEEEEEEHHHEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCE
CSSCSKNFGLYRERIGSCSVIARDAHTANVAQSVLLYVVRCLYSMPPAHGAAIVETILGS
ECCCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
AELTQEWLDELKVMRDRINGNRAILVDKLKANGVDRDFSFIARQKGMFSFLGVNPEQVAR
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEECCCHHHHHH
LQKEFSIYMVGSSRISIAGISEDNVDYLAQSIARVL
HHHHCEEEEEECCEEEEEECCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]