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The map label for this gene is nrdB [H]

Identifier: 126174279

GI number: 126174279

Start: 2385340

End: 2386470

Strand: Reverse

Name: nrdB [H]

Synonym: Sbal_2058

Alternate gene names: 126174279

Gene position: 2386470-2385340 (Counterclockwise)

Preceding gene: 126174280

Following gene: 126174278

Centisome position: 46.54

GC content: 44.56

Gene sequence:

>1131_bases
ATGGCCTACTCTACCTTCTGTCAAACACCCAACGATGCCACCCGTGAACCTATGTTTTTAGGTCAATCGGTCAACGTGGC
TCGTTACGATCAACAAAAATATGAAGTGTTCGAAAAACTGATAGAAAAGCAGTTATCTTTCTTTTGGCGCCCGGAAGAAG
TAGACGTCAGTCGCGATAAAATCGACTACGGTGCATTGCCCGATCATGAAAAACACATCTTTATTTCTAACCTGAAATAC
CAAACCTTACTCGACTCGATTCAAGGTCGCTCACCCAATGTGGCCTTTTTACCACTGGTGTCGCTGCCTGAACTAGAGAC
TTGGATTGAGACTTGGTCTTTCTCTGAGACGATTCACTCGCGCTCATACACCCACATCATTCGCAATATCGTTAACGATC
CTTCAGTGATCTTCGACGATATCGTCGTGAACAAAGAAATCTTAAGCCGTGCGACCGATATCGCCGCTTACTACGATCAC
TTGATCCAATTGACTCAAGTGTTCCATTTACTCGGCGCGGGTACCCATGTTATCGATGGCAAAGAAGTCATAGTCAACAC
TCGTACCCTGAAAAAAGCCTTGTACCTGTGCATGATGTCAGTCAACGCCCTAGAAGCGATTCGTTTCTATGTTAGCTTTG
CCTGCTCATTTGCCTTTGCTGAACGTAAGTTAATGGAAGGTAACGCGAAAATCATTCGCCTGATTGCCCGTGATGAAGCC
TTACACTTAAACAGCACTCAGCATATTTTAAGCATCATGCAAGGCGGTAAAGACGATCCAGAAATGGGTGAAATTGCTGC
AGAATGCCAACAGGAAGCTTTCGATTTATTCTTCAAGGCCGCAGAGCAAGAAAAAGAATGGGCAAAATACCTGTTCAAAG
ACGGCTCTATGATAGGTTTGAATGAACAGATCCTCTGCCAATACGTTGAGTTTATTACTAACCAACGGATGAAGTCGGTG
AATCTGCCGCAACCTTATCTTGAAATAACCAATCCATTACCTTGGATGAAAAACTGGTTAGAAAGCGATGCAGTGCAAGT
CGCGCCTCAGGAAGTGGAAGTGTCTTCATACCTTGTCGGTCAAATCGACTCAGCGGTTGATAGCGATGAATTCCTCGACT
TCGATCTCTAA

Upstream 100 bases:

>100_bases
GCGCGTGTAAAATCTAGTCTTTAACGTTAACGCGGCTCTTACAAATAAAAAGTATAGGGATCCCGATTGAGTGGATCCCT
ATCCATTGGAAAATAGCACC

Downstream 100 bases:

>100_bases
GGCGCTGAAAAGTAACGTTAAAAATGGCATTACAACAGTGACATCGAAAAAACGGCCACAAAACCTGTTTGCGAAGGCGC
CGATCGTGCGCCTTCAAGGT

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MAYSTFCQTPNDATREPMFLGQSVNVARYDQQKYEVFEKLIEKQLSFFWRPEEVDVSRDKIDYGALPDHEKHIFISNLKY
QTLLDSIQGRSPNVAFLPLVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPSVIFDDIVVNKEILSRATDIAAYYDH
LIQLTQVFHLLGAGTHVIDGKEVIVNTRTLKKALYLCMMSVNALEAIRFYVSFACSFAFAERKLMEGNAKIIRLIARDEA
LHLNSTQHILSIMQGGKDDPEMGEIAAECQQEAFDLFFKAAEQEKEWAKYLFKDGSMIGLNEQILCQYVEFITNQRMKSV
NLPQPYLEITNPLPWMKNWLESDAVQVAPQEVEVSSYLVGQIDSAVDSDEFLDFDL

Sequences:

>Translated_376_residues
MAYSTFCQTPNDATREPMFLGQSVNVARYDQQKYEVFEKLIEKQLSFFWRPEEVDVSRDKIDYGALPDHEKHIFISNLKY
QTLLDSIQGRSPNVAFLPLVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPSVIFDDIVVNKEILSRATDIAAYYDH
LIQLTQVFHLLGAGTHVIDGKEVIVNTRTLKKALYLCMMSVNALEAIRFYVSFACSFAFAERKLMEGNAKIIRLIARDEA
LHLNSTQHILSIMQGGKDDPEMGEIAAECQQEAFDLFFKAAEQEKEWAKYLFKDGSMIGLNEQILCQYVEFITNQRMKSV
NLPQPYLEITNPLPWMKNWLESDAVQVAPQEVEVSSYLVGQIDSAVDSDEFLDFDL
>Mature_375_residues
AYSTFCQTPNDATREPMFLGQSVNVARYDQQKYEVFEKLIEKQLSFFWRPEEVDVSRDKIDYGALPDHEKHIFISNLKYQ
TLLDSIQGRSPNVAFLPLVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPSVIFDDIVVNKEILSRATDIAAYYDHL
IQLTQVFHLLGAGTHVIDGKEVIVNTRTLKKALYLCMMSVNALEAIRFYVSFACSFAFAERKLMEGNAKIIRLIARDEAL
HLNSTQHILSIMQGGKDDPEMGEIAAECQQEAFDLFFKAAEQEKEWAKYLFKDGSMIGLNEQILCQYVEFITNQRMKSVN
LPQPYLEITNPLPWMKNWLESDAVQVAPQEVEVSSYLVGQIDSAVDSDEFLDFDL

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Escherichia coli, GI1788567, Length=376, Percent_Identity=75.2659574468085, Blast_Score=613, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 43212; Mature: 43080

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSTFCQTPNDATREPMFLGQSVNVARYDQQKYEVFEKLIEKQLSFFWRPEEVDVSRDK
CCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IDYGALPDHEKHIFISNLKYQTLLDSIQGRSPNVAFLPLVSLPELETWIETWSFSETIHS
CCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
RSYTHIIRNIVNDPSVIFDDIVVNKEILSRATDIAAYYDHLIQLTQVFHLLGAGTHVIDG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
KEVIVNTRTLKKALYLCMMSVNALEAIRFYVSFACSFAFAERKLMEGNAKIIRLIARDEA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCC
LHLNSTQHILSIMQGGKDDPEMGEIAAECQQEAFDLFFKAAEQEKEWAKYLFKDGSMIGL
EECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
NEQILCQYVEFITNQRMKSVNLPQPYLEITNPLPWMKNWLESDAVQVAPQEVEVSSYLVG
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHCCHHHCCCHHHHHHHHHHH
QIDSAVDSDEFLDFDL
HHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AYSTFCQTPNDATREPMFLGQSVNVARYDQQKYEVFEKLIEKQLSFFWRPEEVDVSRDK
CCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IDYGALPDHEKHIFISNLKYQTLLDSIQGRSPNVAFLPLVSLPELETWIETWSFSETIHS
CCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
RSYTHIIRNIVNDPSVIFDDIVVNKEILSRATDIAAYYDHLIQLTQVFHLLGAGTHVIDG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
KEVIVNTRTLKKALYLCMMSVNALEAIRFYVSFACSFAFAERKLMEGNAKIIRLIARDEA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCC
LHLNSTQHILSIMQGGKDDPEMGEIAAECQQEAFDLFFKAAEQEKEWAKYLFKDGSMIGL
EECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
NEQILCQYVEFITNQRMKSVNLPQPYLEITNPLPWMKNWLESDAVQVAPQEVEVSSYLVG
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHCCHHHCCCHHHHHHHHHHH
QIDSAVDSDEFLDFDL
HHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]