Click here to switch to the map view.

The map label for this gene is pabB [H]

Identifier: 126174143

GI number: 126174143

Start: 2226488

End: 2227900

Strand: Reverse

Name: pabB [H]

Synonym: Sbal_1917

Alternate gene names: 126174143

Gene position: 2227900-2226488 (Counterclockwise)

Preceding gene: 126174148

Following gene: 126174142

Centisome position: 43.45

GC content: 49.61

Gene sequence:

>1413_bases
ATGGCAATTAGGGCGTCAAAACAGCTTGCATCACGCCAACTTGACTGGACATTAAGCACCGCAGCACTGTTCGAACACTT
TGCCAATGACTCATGGGCAATCCTGTTAGATTCAGCGAACGCGCCGCATCAGGACGCCAGATTTGACATCATTTGCGCCA
ATCCCATCGCAACATTAGTGACTCAGGGCGAGCGTAGCGATATAAAGCTCATCGATACGAGCTTGAGCTTACCCGAGGCG
ATGGACCCAAACCGTGATCCGTTCGACCTGCTCAACACTTTATTAAATCATTGGTATTCAAAATCTTTTGATTGCGTTCT
GCCCTTCAGTGGCGGCGCCATGGGCAGCTTTAGTTACGACTTAGGCCGTCGTATCGAATCCCTGCCAACAAGCGCTCAGC
AAGATATTCAACTGCCAGAGATGAACATCGGCTTTTACGACTGGGCGTTAGTTTATGATTACCAAGCCCAGTGTTGGCTT
TTATTGCACTATTTAGGTGAAGCAGCACTCGACATTGAATTGAATAAAATTCAAGCGAAAATGGCGTATAAGCCAAATAC
CGCCGAATTCATGCTCACAAGCCCATGGGCAGCACAAATCGATAAAGCCCAATACACGGCAAAATTTGAGGCAGTACAAG
CCTATTTGCACAGCGGCGATTGCTATCAAATAAATTTAACCCAAAGATTTGAAGCTGGCTATCAAGGCGATGAATGGTCG
GCTTATTGCCAACTGCGCAATGCCAATAAAGCACCCTTTTCGGCCTTTATGCGTCTGCCGCAAAATGCGATTTTATCAAT
TTCACCCGAGCGCTTTATTCAACTTCGCGGTGATGATATTCAGACTAAACCCATCAAAGGCACGCTGCCGCGCTGCGCGG
ATCCAACGCTCGACGCCAAAGCCGCGAGCACCCTTGCCGGCTCGCCAAAGGATCGCGCCGAAAACGTCATGATTGTCGAT
TTGCTGCGTAATGATATCGGCAAAGTGGCAACTGCTGGTTCGGTACGTGTACCGCATCTGTTTGAGATTGAAAGCTTTCC
TGCTGTGCATCACCTTGTCAGTACAGTGACGGCTAAGCTTGATGCTAAGTACAGCGCCAGCGATTTGCTGCGCGCGGCGT
TCCCCGGCGGCTCAATCACCGGCGCACCAAAAATTCGCGCCATGGAAATTATTGAAGAGCTCGAACCTTCACGGCGCAGT
CTGTACTGTGGCTCTATGGGTTATATCAGCCAAGATGGCCAAATGGATACCAGTATCACCATTCGCACTATTGTGGCTGA
GCAGGGGAAACTCTATTGCTGGGCGGGCGGCGGCATAGTGGCAGATTCAGAAGTGAATGCCGAGTACCAAGAAACCTTTG
ATAAGATCAGCCGGATTTTGCCTTTACTTGGCGCAGAGCCGCAAAAGCCGTAA

Upstream 100 bases:

>100_bases
CCTTTGCGGCCTAACTTATTTTTGTTTAATTCTTTCTGGGCCAATATGATACTCTTTCCCATCTTTTTGGGCTACATCAC
ATTTTGAATAGGGTTAATCG

Downstream 100 bases:

>100_bases
GCTTTCATACTAAACAGTAACGAGAACGTCGATGGATCAAGCGGAATTTAGACTCAGATTTAATCTGCACCCTTTAGCGC
TGCAAGATCCGGCGGCCTTC

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MAIRASKQLASRQLDWTLSTAALFEHFANDSWAILLDSANAPHQDARFDIICANPIATLVTQGERSDIKLIDTSLSLPEA
MDPNRDPFDLLNTLLNHWYSKSFDCVLPFSGGAMGSFSYDLGRRIESLPTSAQQDIQLPEMNIGFYDWALVYDYQAQCWL
LLHYLGEAALDIELNKIQAKMAYKPNTAEFMLTSPWAAQIDKAQYTAKFEAVQAYLHSGDCYQINLTQRFEAGYQGDEWS
AYCQLRNANKAPFSAFMRLPQNAILSISPERFIQLRGDDIQTKPIKGTLPRCADPTLDAKAASTLAGSPKDRAENVMIVD
LLRNDIGKVATAGSVRVPHLFEIESFPAVHHLVSTVTAKLDAKYSASDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRS
LYCGSMGYISQDGQMDTSITIRTIVAEQGKLYCWAGGGIVADSEVNAEYQETFDKISRILPLLGAEPQKP

Sequences:

>Translated_470_residues
MAIRASKQLASRQLDWTLSTAALFEHFANDSWAILLDSANAPHQDARFDIICANPIATLVTQGERSDIKLIDTSLSLPEA
MDPNRDPFDLLNTLLNHWYSKSFDCVLPFSGGAMGSFSYDLGRRIESLPTSAQQDIQLPEMNIGFYDWALVYDYQAQCWL
LLHYLGEAALDIELNKIQAKMAYKPNTAEFMLTSPWAAQIDKAQYTAKFEAVQAYLHSGDCYQINLTQRFEAGYQGDEWS
AYCQLRNANKAPFSAFMRLPQNAILSISPERFIQLRGDDIQTKPIKGTLPRCADPTLDAKAASTLAGSPKDRAENVMIVD
LLRNDIGKVATAGSVRVPHLFEIESFPAVHHLVSTVTAKLDAKYSASDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRS
LYCGSMGYISQDGQMDTSITIRTIVAEQGKLYCWAGGGIVADSEVNAEYQETFDKISRILPLLGAEPQKP
>Mature_469_residues
AIRASKQLASRQLDWTLSTAALFEHFANDSWAILLDSANAPHQDARFDIICANPIATLVTQGERSDIKLIDTSLSLPEAM
DPNRDPFDLLNTLLNHWYSKSFDCVLPFSGGAMGSFSYDLGRRIESLPTSAQQDIQLPEMNIGFYDWALVYDYQAQCWLL
LHYLGEAALDIELNKIQAKMAYKPNTAEFMLTSPWAAQIDKAQYTAKFEAVQAYLHSGDCYQINLTQRFEAGYQGDEWSA
YCQLRNANKAPFSAFMRLPQNAILSISPERFIQLRGDDIQTKPIKGTLPRCADPTLDAKAASTLAGSPKDRAENVMIVDL
LRNDIGKVATAGSVRVPHLFEIESFPAVHHLVSTVTAKLDAKYSASDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSL
YCGSMGYISQDGQMDTSITIRTIVAEQGKLYCWAGGGIVADSEVNAEYQETFDKISRILPLLGAEPQKP

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=446, Percent_Identity=55.3811659192825, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI1787518, Length=391, Percent_Identity=28.3887468030691, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1786809, Length=201, Percent_Identity=27.8606965174129, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082077, Length=208, Percent_Identity=26.4423076923077, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=443, Percent_Identity=31.1512415349887, Blast_Score=193, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6324361, Length=400, Percent_Identity=28, Blast_Score=155, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 52041; Mature: 51909

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRASKQLASRQLDWTLSTAALFEHFANDSWAILLDSANAPHQDARFDIICANPIATLV
CCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCHHHHHH
TQGERSDIKLIDTSLSLPEAMDPNRDPFDLLNTLLNHWYSKSFDCVLPFSGGAMGSFSYD
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
LGRRIESLPTSAQQDIQLPEMNIGFYDWALVYDYQAQCWLLLHYLGEAALDIELNKIQAK
HHHHHHHCCCCCHHCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCEEEEEEEHEEEE
MAYKPNTAEFMLTSPWAAQIDKAQYTAKFEAVQAYLHSGDCYQINLTQRFEAGYQGDEWS
EEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCCE
AYCQLRNANKAPFSAFMRLPQNAILSISPERFIQLRGDDIQTKPIKGTLPRCADPTLDAK
EEEEECCCCCCHHHHHHHCCCCCEEEECHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCH
AASTLAGSPKDRAENVMIVDLLRNDIGKVATAGSVRVPHLFEIESFPAVHHLVSTVTAKL
HHHHHCCCCCHHHCCEEEEHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
DAKYSASDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSLYCGSMGYISQDGQMDTSIT
CCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCCCEEE
IRTIVAEQGKLYCWAGGGIVADSEVNAEYQETFDKISRILPLLGAEPQKP
EEEEEECCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AIRASKQLASRQLDWTLSTAALFEHFANDSWAILLDSANAPHQDARFDIICANPIATLV
CCCCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCHHHHHH
TQGERSDIKLIDTSLSLPEAMDPNRDPFDLLNTLLNHWYSKSFDCVLPFSGGAMGSFSYD
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
LGRRIESLPTSAQQDIQLPEMNIGFYDWALVYDYQAQCWLLLHYLGEAALDIELNKIQAK
HHHHHHHCCCCCHHCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCEEEEEEEHEEEE
MAYKPNTAEFMLTSPWAAQIDKAQYTAKFEAVQAYLHSGDCYQINLTQRFEAGYQGDEWS
EEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCCE
AYCQLRNANKAPFSAFMRLPQNAILSISPERFIQLRGDDIQTKPIKGTLPRCADPTLDAK
EEEEECCCCCCHHHHHHHCCCCCEEEECHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCH
AASTLAGSPKDRAENVMIVDLLRNDIGKVATAGSVRVPHLFEIESFPAVHHLVSTVTAKL
HHHHHCCCCCHHHCCEEEEHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
DAKYSASDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSLYCGSMGYISQDGQMDTSIT
CCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCCCEEE
IRTIVAEQGKLYCWAGGGIVADSEVNAEYQETFDKISRILPLLGAEPQKP
EEEEEECCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]