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The map label for this gene is fabD [H]

Identifier: 126173947

GI number: 126173947

Start: 1998241

End: 1999167

Strand: Direct

Name: fabD [H]

Synonym: Sbal_1718

Alternate gene names: 126173947

Gene position: 1998241-1999167 (Clockwise)

Preceding gene: 126173946

Following gene: 126173948

Centisome position: 38.97

GC content: 48.87

Gene sequence:

>927_bases
ATGGAAAATGTTGCTTTTGTATTTCCAGGCCAAGGTTCACAAGCCCTAGGCATGTTAGCCGAGCTTGCCGAATCACACGC
CGTTGTCGGGCAAACCTTTGCCGAAGCGAGTGACGTCTTAGGTTATGATTTGTGGGCATTGGTTCAGCAAGGTCCTGTTG
AAACCTTAAATGAAACCGATAAAACCCAGCCAGCCCTATTAGCGGCGAGCGTGGCGATTTGGCGTGCCTATGTGGCTTCA
GGCAAACCTATGCCAGCCATGTTAGCGGGTCACAGCTTAGGCGAGTATTCTGCTTTAGTGTGCGCCGGAGTCATGGATTT
TAAAGACGCGATTAAGTTGGTGGAGTTACGCGGTCAACTTATGCAGCAAGCGGTTCCTGCTGGCACAGGCGCCATGTATG
CCATTATCGGTTTAGATAACGAGGGTATCGCGAATGCTTGCGCTGAAGCGGCTCAAGGCGACGTGGTGAGCCCAGTTAAC
TTCAACAGCCCTGGTCAAGTTGTTATCGCGGGTCAAAAAGACGCGGTTGAGCGTGCAGCAGCGGCTTGTAAAGCTGCGGG
CGCTAAAATGGCGGTAGCGTTACTTGTCAGCGTGCCATCACACTGCGCATTAATGAAACCTGCGGCGGATAAACTGGCCG
TGGCATTAAACGATGTACAGTTTAATCCCCCAACTATTACTGTAATTAACAACGTTGATGTGGCATCACCAACGTCTGCT
GATGACATTAAAGATGCATTAGTACGTCAGTTATATTGTCCTGTCCGCTGGAGCGAAACTGTTGAGCTAATGGCCCAAAA
AGGCATAACCCAACTGGTGGAATGTGGTCCTGGTAAAGTATTGACAGGATTAGCAAAACGAATTAATAAATCACTATCAG
CCCAAGCGGTTAATGATGTCGCTTCATTAGCAGCATTAACTGAGTAA

Upstream 100 bases:

>100_bases
CTGGTTTTGCGTGGGGCAGTGCGCTCATTCGCTTCTAAGTTCTACATGTGTTTTCCACATGATTTTTCAATAAATTAAGT
TAGCCATAGGTAATTTGAAT

Downstream 100 bases:

>100_bases
GGAGTTTGTATGAGTTTTAACCTGAATTTAACAGGCAAAGTGGCTTTGGTGACTGGTGCGAGCCGCGGTATTGGCCGTGC
GATCGCTGAGACACTGGTCG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MENVAFVFPGQGSQALGMLAELAESHAVVGQTFAEASDVLGYDLWALVQQGPVETLNETDKTQPALLAASVAIWRAYVAS
GKPMPAMLAGHSLGEYSALVCAGVMDFKDAIKLVELRGQLMQQAVPAGTGAMYAIIGLDNEGIANACAEAAQGDVVSPVN
FNSPGQVVIAGQKDAVERAAAACKAAGAKMAVALLVSVPSHCALMKPAADKLAVALNDVQFNPPTITVINNVDVASPTSA
DDIKDALVRQLYCPVRWSETVELMAQKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDVASLAALTE

Sequences:

>Translated_308_residues
MENVAFVFPGQGSQALGMLAELAESHAVVGQTFAEASDVLGYDLWALVQQGPVETLNETDKTQPALLAASVAIWRAYVAS
GKPMPAMLAGHSLGEYSALVCAGVMDFKDAIKLVELRGQLMQQAVPAGTGAMYAIIGLDNEGIANACAEAAQGDVVSPVN
FNSPGQVVIAGQKDAVERAAAACKAAGAKMAVALLVSVPSHCALMKPAADKLAVALNDVQFNPPTITVINNVDVASPTSA
DDIKDALVRQLYCPVRWSETVELMAQKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDVASLAALTE
>Mature_308_residues
MENVAFVFPGQGSQALGMLAELAESHAVVGQTFAEASDVLGYDLWALVQQGPVETLNETDKTQPALLAASVAIWRAYVAS
GKPMPAMLAGHSLGEYSALVCAGVMDFKDAIKLVELRGQLMQQAVPAGTGAMYAIIGLDNEGIANACAEAAQGDVVSPVN
FNSPGQVVIAGQKDAVERAAAACKAAGAKMAVALLVSVPSHCALMKPAADKLAVALNDVQFNPPTITVINNVDVASPTSA
DDIKDALVRQLYCPVRWSETVELMAQKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDVASLAALTE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=311, Percent_Identity=33.1189710610932, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=41.8181818181818, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=67.5324675324675, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=30.4054054054054, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=292, Percent_Identity=28.7671232876712, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24665753, Length=318, Percent_Identity=31.7610062893082, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31871; Mature: 31871

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVAFVFPGQGSQALGMLAELAESHAVVGQTFAEASDVLGYDLWALVQQGPVETLNETD
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
KTQPALLAASVAIWRAYVASGKPMPAMLAGHSLGEYSALVCAGVMDFKDAIKLVELRGQL
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMYAIIGLDNEGIANACAEAAQGDVVSPVNFNSPGQVVIAGQKDAVERAA
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHH
AACKAAGAKMAVALLVSVPSHCALMKPAADKLAVALNDVQFNPPTITVINNVDVASPTSA
HHHHHCCHHHHHHHHHHCCCHHHCCCCCHHHHHEEEECEEECCCEEEEEECCCCCCCCCH
DDIKDALVRQLYCPVRWSETVELMAQKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLAALTE
HHHHHHCC
>Mature Secondary Structure
MENVAFVFPGQGSQALGMLAELAESHAVVGQTFAEASDVLGYDLWALVQQGPVETLNETD
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
KTQPALLAASVAIWRAYVASGKPMPAMLAGHSLGEYSALVCAGVMDFKDAIKLVELRGQL
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMYAIIGLDNEGIANACAEAAQGDVVSPVNFNSPGQVVIAGQKDAVERAA
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHH
AACKAAGAKMAVALLVSVPSHCALMKPAADKLAVALNDVQFNPPTITVINNVDVASPTSA
HHHHHCCHHHHHHHHHHCCCHHHCCCCCHHHHHEEEECEEECCCEEEEEECCCCCCCCCH
DDIKDALVRQLYCPVRWSETVELMAQKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLAALTE
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]