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The map label for this gene is fabH [H]

Identifier: 126173946

GI number: 126173946

Start: 1997219

End: 1998178

Strand: Direct

Name: fabH [H]

Synonym: Sbal_1717

Alternate gene names: 126173946

Gene position: 1997219-1998178 (Clockwise)

Preceding gene: 126173945

Following gene: 126173947

Centisome position: 38.95

GC content: 48.33

Gene sequence:

>960_bases
ATGCATACAAAAATTCTCGGAACTGGTAGTTATCTGCCAGTGCAGGTGCGTAGCAATCAAGATTTGGAAAAAATGGTGGA
AACCACTGACCAATGGATTGTTGAACGTACAGGTATATCAGAACGTCGCATTGCGGCCTTCGATGAAACCGTTTCAACTA
TGGGCTACCAAGCGGCACTCAAAGCGCTGGAAATGGCTGGCATAGAAGCATCAGATTTAGACATGATCGTTTGCGGCACC
ACCAGTGCACCAAATGCTTTTCCGGCTGCGGCCTGTGAAATCCAAGCCATGCTTGGCGTGCATACCATTCCAGCATTCGA
CATCGCAGCGGCTTGTTCAGGCTTTGTTTATGCTTTATCTGTTGCTGACCAATTTGTTAAAACGGGCGCTGCTAAAAAAG
TCTTAGTGATTGGTGCCGATGTGCTGTCTCGCCTATGTGAGCCTGAAGATCGTTCAACGATTATTTTATTTGGTGATGGT
GCGGGCGCCGTTGTGATTGGTGCATCTGAAACGCCAGGGATCATTTCTACCCACATTTATGCCGATGGTCGCCAAGGCGA
CTTATTGAAATGCGCTTTCCCACCACGCCAAGGCGAAACCTCTGAAGCGGTCGGTTTTATGACCATGAAGGGTAACGATG
TCTTTAAAGTGGCAGTGACTCAATTGTCCCATGTTGTGACTGAGACGCTGCGCATCAACAATATCGATAAGTCAGAAATT
GATTGGTTAGTGCCACATCAAGCTAACTTCCGTATTATCAATGCTACCGCCAAAAAGCTCGATATGAGTCTCGATAAAGT
CGTATTGACCTTAGCTAAACACGGGAATACCTCCGCTGCATCTGTGCCCATCGCATTAGATGAAGCCGTGCGTGATGGCC
GGATTCAGCGTGGACAACTCCTGCTGCTTGAGGCCTTCGGTGCTGGTTTTGCGTGGGGCAGTGCGCTCATTCGCTTCTAA

Upstream 100 bases:

>100_bases
AATTAGTTTGGCAGTAACGGAAGCTCAACGTCGACTCCCTGAAATGATAAAAGATCGTTTGGAGTCGATTCTTTTAGATA
TAAATAACTGATCCCTCCTT

Downstream 100 bases:

>100_bases
GTTCTACATGTGTTTTCCACATGATTTTTCAATAAATTAAGTTAGCCATAGGTAATTTGAATATGGAAAATGTTGCTTTT
GTATTTCCAGGCCAAGGTTC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MHTKILGTGSYLPVQVRSNQDLEKMVETTDQWIVERTGISERRIAAFDETVSTMGYQAALKALEMAGIEASDLDMIVCGT
TSAPNAFPAAACEIQAMLGVHTIPAFDIAAACSGFVYALSVADQFVKTGAAKKVLVIGADVLSRLCEPEDRSTIILFGDG
AGAVVIGASETPGIISTHIYADGRQGDLLKCAFPPRQGETSEAVGFMTMKGNDVFKVAVTQLSHVVTETLRINNIDKSEI
DWLVPHQANFRIINATAKKLDMSLDKVVLTLAKHGNTSAASVPIALDEAVRDGRIQRGQLLLLEAFGAGFAWGSALIRF

Sequences:

>Translated_319_residues
MHTKILGTGSYLPVQVRSNQDLEKMVETTDQWIVERTGISERRIAAFDETVSTMGYQAALKALEMAGIEASDLDMIVCGT
TSAPNAFPAAACEIQAMLGVHTIPAFDIAAACSGFVYALSVADQFVKTGAAKKVLVIGADVLSRLCEPEDRSTIILFGDG
AGAVVIGASETPGIISTHIYADGRQGDLLKCAFPPRQGETSEAVGFMTMKGNDVFKVAVTQLSHVVTETLRINNIDKSEI
DWLVPHQANFRIINATAKKLDMSLDKVVLTLAKHGNTSAASVPIALDEAVRDGRIQRGQLLLLEAFGAGFAWGSALIRF
>Mature_319_residues
MHTKILGTGSYLPVQVRSNQDLEKMVETTDQWIVERTGISERRIAAFDETVSTMGYQAALKALEMAGIEASDLDMIVCGT
TSAPNAFPAAACEIQAMLGVHTIPAFDIAAACSGFVYALSVADQFVKTGAAKKVLVIGADVLSRLCEPEDRSTIILFGDG
AGAVVIGASETPGIISTHIYADGRQGDLLKCAFPPRQGETSEAVGFMTMKGNDVFKVAVTQLSHVVTETLRINNIDKSEI
DWLVPHQANFRIINATAKKLDMSLDKVVLTLAKHGNTSAASVPIALDEAVRDGRIQRGQLLLLEAFGAGFAWGSALIRF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=319, Percent_Identity=67.7115987460815, Blast_Score=451, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34072; Mature: 34072

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTKILGTGSYLPVQVRSNQDLEKMVETTDQWIVERTGISERRIAAFDETVSTMGYQAAL
CCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KALEMAGIEASDLDMIVCGTTSAPNAFPAAACEIQAMLGVHTIPAFDIAAACSGFVYALS
HHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VADQFVKTGAAKKVLVIGADVLSRLCEPEDRSTIILFGDGAGAVVIGASETPGIISTHIY
HHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEE
ADGRQGDLLKCAFPPRQGETSEAVGFMTMKGNDVFKVAVTQLSHVVTETLRINNIDKSEI
ECCCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCHHHC
DWLVPHQANFRIINATAKKLDMSLDKVVLTLAKHGNTSAASVPIALDEAVRDGRIQRGQL
CEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCEECEEHHHHHHCCCCCCCCE
LLLEAFGAGFAWGSALIRF
EEEEECCCCHHHHHHHHCC
>Mature Secondary Structure
MHTKILGTGSYLPVQVRSNQDLEKMVETTDQWIVERTGISERRIAAFDETVSTMGYQAAL
CCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KALEMAGIEASDLDMIVCGTTSAPNAFPAAACEIQAMLGVHTIPAFDIAAACSGFVYALS
HHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VADQFVKTGAAKKVLVIGADVLSRLCEPEDRSTIILFGDGAGAVVIGASETPGIISTHIY
HHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEE
ADGRQGDLLKCAFPPRQGETSEAVGFMTMKGNDVFKVAVTQLSHVVTETLRINNIDKSEI
ECCCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCHHHC
DWLVPHQANFRIINATAKKLDMSLDKVVLTLAKHGNTSAASVPIALDEAVRDGRIQRGQL
CEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCEECEEHHHHHHCCCCCCCCE
LLLEAFGAGFAWGSALIRF
EEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]