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The map label for this gene is dhaAF [H]

Identifier: 126173785

GI number: 126173785

Start: 1803802

End: 1804710

Strand: Direct

Name: dhaAF [H]

Synonym: Sbal_1551

Alternate gene names: 126173785

Gene position: 1803802-1804710 (Clockwise)

Preceding gene: 126173784

Following gene: 126173786

Centisome position: 35.18

GC content: 48.95

Gene sequence:

>909_bases
ATGTTAGACACTCTGTTGCCTTTTAAACGTCATTTTCTTAGCCGTAATGGCAACAAGCTGCATTATATCAACGAGGGCCA
AGGCGAACCTGTGGTGATGGTTCACGGTAATCCTAGCTGGTCGTTTTACTACCGCAATCTCGTTAGCGCCTTAAAAGACA
CGCATCAATGCATAGTGCCAGATCATATCGGCTGTGGTCTGTCGGATAAGCCAGACGATAGCGGCTATGACTATACCCTT
AAGAACCGCATCGACGATCTCGAAGCTTTGCTCGATAGCCTGAATGTGAAAGAAAACATTACCTTAGTTGTACACGACTG
GGGCGGCATGATAGGTATGGGTTATGCGGCGCGTTATCCTGAGCGTATCAAACGCCTAGTGATTTTGAACACGGGTGCTT
TCCATCTGCCTGAGACTAAGCCGTTTCCTTGGCCGCTGTGGATCTGTCGTAATACTCTGCTAGGCACAGTGCTGGTACGT
GGTTTTAATGCCTTTTCGTCTATCGCCTCATATGTGGGCGTTAAGCGTCAGCCAATGTCCAAATACATTCGTGAGGCGTA
TGTCGCACCGTTTAACTCTTGGGCCAATCGCATTTCGACGCTGCGTTTTGTACAGGATATTCCGCTGCGTGAAGACGATA
GAAACTATCAGTTAGTCTCTGATATCGCTGCGAGTTTACCGCAGTTTGCCAAAGTTCCGACTTTGATTTGCTGGGGCCTG
AAGGACTTTGTATTCGATAAGCACTTTTTAGCAAAATGGCGTCAGCACATGCCCCATGCGGCCGTGCATGAATTTGCCGA
TTGTGGTCACTACATTCTGGAAGATGCCAGCGATGAAGTGATTGCCCATATCAAGGGCTTTATGGCCGACGACCAAGCAG
CGGCGCCGTCCGAACAGGCCGCAGGTTAA

Upstream 100 bases:

>100_bases
TTCAGTTGATAGCTCAGTCTGTCGTTCAGTCGATAAGCTAAGCCTGCTAAAAATAAACCATTATTCGCTCTCATAAATTG
AACAAAAGATAGGAAGCGTC

Downstream 100 bases:

>100_bases
TGTCGACCTTGCTTGAGACTGAAGTGACTCCTTTGTTGGCTGCTGTAGTGACGCCGTTGGATACGTCACTTTTAACGGGC
ACTTCTGCGTCAGCAATGGC

Product: alpha/beta hydrolase fold domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MLDTLLPFKRHFLSRNGNKLHYINEGQGEPVVMVHGNPSWSFYYRNLVSALKDTHQCIVPDHIGCGLSDKPDDSGYDYTL
KNRIDDLEALLDSLNVKENITLVVHDWGGMIGMGYAARYPERIKRLVILNTGAFHLPETKPFPWPLWICRNTLLGTVLVR
GFNAFSSIASYVGVKRQPMSKYIREAYVAPFNSWANRISTLRFVQDIPLREDDRNYQLVSDIAASLPQFAKVPTLICWGL
KDFVFDKHFLAKWRQHMPHAAVHEFADCGHYILEDASDEVIAHIKGFMADDQAAAPSEQAAG

Sequences:

>Translated_302_residues
MLDTLLPFKRHFLSRNGNKLHYINEGQGEPVVMVHGNPSWSFYYRNLVSALKDTHQCIVPDHIGCGLSDKPDDSGYDYTL
KNRIDDLEALLDSLNVKENITLVVHDWGGMIGMGYAARYPERIKRLVILNTGAFHLPETKPFPWPLWICRNTLLGTVLVR
GFNAFSSIASYVGVKRQPMSKYIREAYVAPFNSWANRISTLRFVQDIPLREDDRNYQLVSDIAASLPQFAKVPTLICWGL
KDFVFDKHFLAKWRQHMPHAAVHEFADCGHYILEDASDEVIAHIKGFMADDQAAAPSEQAAG
>Mature_302_residues
MLDTLLPFKRHFLSRNGNKLHYINEGQGEPVVMVHGNPSWSFYYRNLVSALKDTHQCIVPDHIGCGLSDKPDDSGYDYTL
KNRIDDLEALLDSLNVKENITLVVHDWGGMIGMGYAARYPERIKRLVILNTGAFHLPETKPFPWPLWICRNTLLGTVLVR
GFNAFSSIASYVGVKRQPMSKYIREAYVAPFNSWANRISTLRFVQDIPLREDDRNYQLVSDIAASLPQFAKVPTLICWGL
KDFVFDKHFLAKWRQHMPHAAVHEFADCGHYILEDASDEVIAHIKGFMADDQAAAPSEQAAG

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Has a broad substrate specificity, which includes mono- and di- chlorinated

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=117, Percent_Identity=32.4786324786325, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562298, Length=307, Percent_Identity=23.1270358306189, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17554012, Length=288, Percent_Identity=22.9166666666667, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 34263; Mature: 34263

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTLLPFKRHFLSRNGNKLHYINEGQGEPVVMVHGNPSWSFYYRNLVSALKDTHQCIVP
CCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCEECC
DHIGCGLSDKPDDSGYDYTLKNRIDDLEALLDSLNVKENITLVVHDWGGMIGMGYAARYP
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHCCHHHHCH
ERIKRLVILNTGAFHLPETKPFPWPLWICRNTLLGTVLVRGFNAFSSIASYVGVKRQPMS
HHHCEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
KYIREAYVAPFNSWANRISTLRFVQDIPLREDDRNYQLVSDIAASLPQFAKVPTLICWGL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHCHHHHHHHH
KDFVFDKHFLAKWRQHMPHAAVHEFADCGHYILEDASDEVIAHIKGFMADDQAAAPSEQA
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCC
AG
CC
>Mature Secondary Structure
MLDTLLPFKRHFLSRNGNKLHYINEGQGEPVVMVHGNPSWSFYYRNLVSALKDTHQCIVP
CCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCEECC
DHIGCGLSDKPDDSGYDYTLKNRIDDLEALLDSLNVKENITLVVHDWGGMIGMGYAARYP
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHCCHHHHCH
ERIKRLVILNTGAFHLPETKPFPWPLWICRNTLLGTVLVRGFNAFSSIASYVGVKRQPMS
HHHCEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
KYIREAYVAPFNSWANRISTLRFVQDIPLREDDRNYQLVSDIAASLPQFAKVPTLICWGL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHCHHHHHHHH
KDFVFDKHFLAKWRQHMPHAAVHEFADCGHYILEDASDEVIAHIKGFMADDQAAAPSEQA
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094681; 10735862 [H]