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The map label for this gene is betT [H]

Identifier: 126173780

GI number: 126173780

Start: 1797960

End: 1799936

Strand: Direct

Name: betT [H]

Synonym: Sbal_1546

Alternate gene names: 126173780

Gene position: 1797960-1799936 (Clockwise)

Preceding gene: 126173779

Following gene: 126173781

Centisome position: 35.07

GC content: 48.51

Gene sequence:

>1977_bases
ATGTCGATCAAGTCGAGTATTAATCCGCCGGTATTTTATTCGTCGGTCTTTTTCATCATCTTGATGGTGATGATTTGTGC
AGTATGGCCCACAGAGGCTAACACCGTTTTTAGATCAATACAGTCATGGATAGAAGTGAAAGCCGGTTGGCTTTACATTT
TGAGCGTGGCGTTTTTCCTGATTTTTATCATCTTTGTCATGGTCAGTCGCTTTGGCGATATCAAACTCGGGCCAGATCAT
TCTGTGCCGGATTACAGCTATAAAAGCTGGATTGCCATGTTGTTTTCGGCAGGTATGGGTATTGGCCTGATGTTTTTTGG
GGTCGCCGAACCTGTAATGCACTATCTGGCGCCGCCAGATGCTACACCTGAGAGTCTCGCCGCCGCAAAAGAGGCGATGA
AGATTACTTTCTTCCATTGGGGACTGCATGCTTGGGCGATTTATGCCGTAGTGGCATTGAGTCTGGCCTACTTCTCCTAT
CGTCATAAGTTACCGCTACTGCCACGAAGTGCCCTTTATCCCTTAATTGGTGAACGCATTTATGGTCCTATTGGCCATAT
TGTCGATACCTTTGCCGTGCTCGGCACTATGTTTGGGGTGGCGACATCACTGGGCTTTGGGGTGTTGCAGGTTAACTCGG
GTCTGAGTTATCTATTTGAAGGTTTACCTAATAACGCTGTAGTGCAAGTGTGCTTGATCATCGGCATTACCTTGCTCGCG
ACCCTGTCGGTGTTTTCTGGCCTCGACAAAGGCGTCAAACGCTTAAGCGAACTCAATCTTGGCCTCGCGATTATCTTATT
GCTTATCGTCTTGATCTTGGGCCCTACAGTCATGCTGTTGCAGGCCTTTGTGCAAAACACTGGCAGTTACTTAAGTGATT
TGGTTGGTAAAACCTTTAACTTGTACGCCTATCAACATAAGGAAGATTGGCTCGGCGGCGGGACCTTACTCTATTGGGGC
TGGTGGATTTCTTGGTCACCTTTTGTCGGTACCTTTATTGCGCGCGTGAGCCGCGGTCGTACCATCCGTGAGTTTTTGAT
TGGTGTGTTATTTGTGCCATCGGCGCTGACCTTCCTGTGGATGACAGTGTTTGGTAACTCGGCGATTGATTCGATTATGA
ATCAAGGCGCAACCTACCTTGCCGAGGCGGTGAATACCGATGTGTCAGTGGCCTTGTTTGTGTTTTTCGAGCACATGCCG
TTCCCGACCTTACTCTCAGGGATTGCGATTTGTTTAGTCGTGACCTTCTTTGTGACCTCGTCGGATTCGGGGTCCTTAGT
GATTGATAATTTGACCTCGGGCGGCGATAACAATGCGCCTGTATGGCAGAGGATCTTCTGGGCCCTGTTGCAAGGGGTTG
TGGCCTCGGTATTGTTGTTGGCTGGTGGTTTACAGGCGCTGCAAACGGCGGCTATCGCCAGCGCCATGCCGTTCCTCGTG
GTGATGTTATTCATGTGTCTGGGATTATTTAAAGCCCTGAAGAATGACTGGCTTAAGATCAACAGCGTGCAATTACACAA
TACCAGTGTGCAGTACGCCAAAACCAACATGAGCTGGGAAGAACGCATTGGCGTGCTCGTCTCGCATCCCACCCATGAAG
AAGCGCAAGTGTTCTTGAATAATGTTGCGACGCCTGCTTTGTCTAAGGTGTGTCAACACTTTATGGCCAAAGGCATAGTG
GCCGATCTCGAATACTTAGATGGCCGCGTACGTTTGGTGATCAGCAACGAGGTGAACTTGCCCTTTGTGTACGGAGTACG
AACGCGCTGTTTTGACATTACTAACCCGATAGGGACTGAAATCGAGCAGGGCAATACCTTGTATTACCGCGCCGAAGTGT
ATTTAGAACAAGGTGGTCAGCATTACGATGTGATGGGGTATACCGAAGAGCAAATCCTCGCTGATGTGGTGACTCAGTAT
GAAAAATACTTACACTATTTGCATCTGTCGAATGCCGATCATGCCCACATAAGCTAA

Upstream 100 bases:

>100_bases
CCGCAGCATTAAACATATTTTGAGTATAAGTTTTGTTCTATCTCTCCGTTGGTGCGCTGAGATATTTGGAGAGTGAACCC
GCTAGAAATAGGGAGAGTCA

Downstream 100 bases:

>100_bases
GTAACGTAAGCTAGGTAAGTTAAGCAAGGTAAGCCAGTAACGTAAGTCGGTTTAGCCATTTGCGTCTACAAATCGCGCAC
CATTAACCCGCAAAGTGCGG

Product: choline/carnitine/betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 658; Mature: 657

Protein sequence:

>658_residues
MSIKSSINPPVFYSSVFFIILMVMICAVWPTEANTVFRSIQSWIEVKAGWLYILSVAFFLIFIIFVMVSRFGDIKLGPDH
SVPDYSYKSWIAMLFSAGMGIGLMFFGVAEPVMHYLAPPDATPESLAAAKEAMKITFFHWGLHAWAIYAVVALSLAYFSY
RHKLPLLPRSALYPLIGERIYGPIGHIVDTFAVLGTMFGVATSLGFGVLQVNSGLSYLFEGLPNNAVVQVCLIIGITLLA
TLSVFSGLDKGVKRLSELNLGLAIILLLIVLILGPTVMLLQAFVQNTGSYLSDLVGKTFNLYAYQHKEDWLGGGTLLYWG
WWISWSPFVGTFIARVSRGRTIREFLIGVLFVPSALTFLWMTVFGNSAIDSIMNQGATYLAEAVNTDVSVALFVFFEHMP
FPTLLSGIAICLVVTFFVTSSDSGSLVIDNLTSGGDNNAPVWQRIFWALLQGVVASVLLLAGGLQALQTAAIASAMPFLV
VMLFMCLGLFKALKNDWLKINSVQLHNTSVQYAKTNMSWEERIGVLVSHPTHEEAQVFLNNVATPALSKVCQHFMAKGIV
ADLEYLDGRVRLVISNEVNLPFVYGVRTRCFDITNPIGTEIEQGNTLYYRAEVYLEQGGQHYDVMGYTEEQILADVVTQY
EKYLHYLHLSNADHAHIS

Sequences:

>Translated_658_residues
MSIKSSINPPVFYSSVFFIILMVMICAVWPTEANTVFRSIQSWIEVKAGWLYILSVAFFLIFIIFVMVSRFGDIKLGPDH
SVPDYSYKSWIAMLFSAGMGIGLMFFGVAEPVMHYLAPPDATPESLAAAKEAMKITFFHWGLHAWAIYAVVALSLAYFSY
RHKLPLLPRSALYPLIGERIYGPIGHIVDTFAVLGTMFGVATSLGFGVLQVNSGLSYLFEGLPNNAVVQVCLIIGITLLA
TLSVFSGLDKGVKRLSELNLGLAIILLLIVLILGPTVMLLQAFVQNTGSYLSDLVGKTFNLYAYQHKEDWLGGGTLLYWG
WWISWSPFVGTFIARVSRGRTIREFLIGVLFVPSALTFLWMTVFGNSAIDSIMNQGATYLAEAVNTDVSVALFVFFEHMP
FPTLLSGIAICLVVTFFVTSSDSGSLVIDNLTSGGDNNAPVWQRIFWALLQGVVASVLLLAGGLQALQTAAIASAMPFLV
VMLFMCLGLFKALKNDWLKINSVQLHNTSVQYAKTNMSWEERIGVLVSHPTHEEAQVFLNNVATPALSKVCQHFMAKGIV
ADLEYLDGRVRLVISNEVNLPFVYGVRTRCFDITNPIGTEIEQGNTLYYRAEVYLEQGGQHYDVMGYTEEQILADVVTQY
EKYLHYLHLSNADHAHIS
>Mature_657_residues
SIKSSINPPVFYSSVFFIILMVMICAVWPTEANTVFRSIQSWIEVKAGWLYILSVAFFLIFIIFVMVSRFGDIKLGPDHS
VPDYSYKSWIAMLFSAGMGIGLMFFGVAEPVMHYLAPPDATPESLAAAKEAMKITFFHWGLHAWAIYAVVALSLAYFSYR
HKLPLLPRSALYPLIGERIYGPIGHIVDTFAVLGTMFGVATSLGFGVLQVNSGLSYLFEGLPNNAVVQVCLIIGITLLAT
LSVFSGLDKGVKRLSELNLGLAIILLLIVLILGPTVMLLQAFVQNTGSYLSDLVGKTFNLYAYQHKEDWLGGGTLLYWGW
WISWSPFVGTFIARVSRGRTIREFLIGVLFVPSALTFLWMTVFGNSAIDSIMNQGATYLAEAVNTDVSVALFVFFEHMPF
PTLLSGIAICLVVTFFVTSSDSGSLVIDNLTSGGDNNAPVWQRIFWALLQGVVASVLLLAGGLQALQTAAIASAMPFLVV
MLFMCLGLFKALKNDWLKINSVQLHNTSVQYAKTNMSWEERIGVLVSHPTHEEAQVFLNNVATPALSKVCQHFMAKGIVA
DLEYLDGRVRLVISNEVNLPFVYGVRTRCFDITNPIGTEIEQGNTLYYRAEVYLEQGGQHYDVMGYTEEQILADVVTQYE
KYLHYLHLSNADHAHIS

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=664, Percent_Identity=38.7048192771084, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1786224, Length=503, Percent_Identity=27.037773359841, Blast_Score=181, Evalue=9e-47,
Organism=Escherichia coli, GI1788102, Length=460, Percent_Identity=29.5652173913043, Blast_Score=178, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 72858; Mature: 72727

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKSSINPPVFYSSVFFIILMVMICAVWPTEANTVFRSIQSWIEVKAGWLYILSVAFFL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFIIFVMVSRFGDIKLGPDHSVPDYSYKSWIAMLFSAGMGIGLMFFGVAEPVMHYLAPPD
HHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
ATPESLAAAKEAMKITFFHWGLHAWAIYAVVALSLAYFSYRHKLPLLPRSALYPLIGERI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
YGPIGHIVDTFAVLGTMFGVATSLGFGVLQVNSGLSYLFEGLPNNAVVQVCLIIGITLLA
HCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHH
TLSVFSGLDKGVKRLSELNLGLAIILLLIVLILGPTVMLLQAFVQNTGSYLSDLVGKTFN
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEE
LYAYQHKEDWLGGGTLLYWGWWISWSPFVGTFIARVSRGRTIREFLIGVLFVPSALTFLW
EEEEECCHHCCCCCEEEEEEHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
MTVFGNSAIDSIMNQGATYLAEAVNTDVSVALFVFFEHMPFPTLLSGIAICLVVTFFVTS
HHHHCCHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
SDSGSLVIDNLTSGGDNNAPVWQRIFWALLQGVVASVLLLAGGLQALQTAAIASAMPFLV
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VMLFMCLGLFKALKNDWLKINSVQLHNTSVQYAKTNMSWEERIGVLVSHPTHEEAQVFLN
HHHHHHHHHHHHHHCCCEEECEEEEECCCCHHHCCCCCHHHHCCEEEECCCCHHHHHHHH
NVATPALSKVCQHFMAKGIVADLEYLDGRVRLVISNEVNLPFVYGVRTRCFDITNPIGTE
HCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEECCHHHHEECCCCCCCC
IEQGNTLYYRAEVYLEQGGQHYDVMGYTEEQILADVVTQYEKYLHYLHLSNADHAHIS
CCCCCEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SIKSSINPPVFYSSVFFIILMVMICAVWPTEANTVFRSIQSWIEVKAGWLYILSVAFFL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH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CCCCCEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]