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The map label for this gene is yngF [H]

Identifier: 126173737

GI number: 126173737

Start: 1743095

End: 1744246

Strand: Direct

Name: yngF [H]

Synonym: Sbal_1499

Alternate gene names: 126173737

Gene position: 1743095-1744246 (Clockwise)

Preceding gene: 126173736

Following gene: 126173738

Centisome position: 34.0

GC content: 50.17

Gene sequence:

>1152_bases
ATGACTAATGTAGTAGATAACGTAAATCAGGCCACGACCACGCAAAACGTGGTTTTTCAAACCTTAGCCACCGCGTCCGG
TAAGTTGATTGGGGTGGTGACACTCAATGTGGAAAAAGCCCTCAACGCCTTAGATTTAGACATGGTGCGCGCTATGACGG
CGCAGCTCAATCTATGGAAGAAAGACTCGCTTGTCGCTTGTATCGTGTTAGATGGCAGCGGTGAGAAGGCTTTTTGTGCG
GGTGGTGATGTGCGCGCTTTATACCATGCATCCATTGCCGCTAAAGGACAAGTGACTGAGGAGGCAAAGGTTTTCTTCGA
AGAGGAATATCGCCTCGATTATCTACTGCATACCTTTGGCAAACCTGTGTTGGTGTGGGGCGACGGTATTGTGATGGGCG
GTGGGCTCGGTTTGATGGCGGGCGCAAGCCACAGAGTCGTTACCGAAACTTCGCGCATTGCTATGCCTGAAGTGACGATT
GGCCTGTACCCCGATGTGGGCGGCAGTTATTTCCTTAATCGTATGCAGGGCAAAATGGGACTGTTTTTAGGGCTCACGGC
CTATCAACTCAATGCCGCCGATGCCTGCTATGTGGGCCTTGCGGATCATTACCTGAACCGTGACGACAAAGAACTGATGT
TCGATGCCATGGCCACCTTAGATTGGAGCGATACACCGGCGCTTAATCATCAACGCTTAGATAGCATGATCAACGAGTTA
TCTAATCAAGTGGATATCCCGAAGGGCGAAAGTGTATTGGCGGACAGCCAAGATAATATCGACCGACTGATGGCGGGGAG
TTTAGAGGATATTGTCACCCGTATGTCGACCTTAGCGTCGGAGGATGCTTGGTTAATGAAGGCGCGCGACACCTTCCTTG
CGGGCAGTCCTATCAGCTGGCATCTGGTTAATATCCAATCACAACTTGGTACTAAGTTAAGCTTAGCTGAATGTTTTAAA
TGGGAATTAACCGCCAGCGTTAACGTGTGTGCCCATGGTGATTTCTGTGAAGGGGTTCGCGCACTCTTGATTGATAAAGA
CAGACAACCCCAGTGGCGCTTTAAGGATGTGAACTCAGTGCCTACCGCCGTACTTGAGCAAATATTGACTTCCCCTTGGG
GCGAGGCGCATCCCTTTAGCCAACTGAGCTAA

Upstream 100 bases:

>100_bases
TTGAGCGTGAATTATTTGTCGGGTTATTTGATACCGAAGATCAGGCCGAAGGCGTGAATGCGTTTTTGGGCAAACGTAAA
GCTGATTGGAAGAACCGCTA

Downstream 100 bases:

>100_bases
GCGTTGAGTTGATTATGCATAGACTTGGCTAAGCGTTGACTTGATTAGCGCAGGCTTGATTAGTGCTGAGTGTATAGGCT
CAGCCAAGCTCGCTTTACTC

Product: enoyl-CoA hydratase/isomerase

Products: trans-2-enoyl-CoA; trans-3-enoyl-CoA; H2O

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTNVVDNVNQATTTQNVVFQTLATASGKLIGVVTLNVEKALNALDLDMVRAMTAQLNLWKKDSLVACIVLDGSGEKAFCA
GGDVRALYHASIAAKGQVTEEAKVFFEEEYRLDYLLHTFGKPVLVWGDGIVMGGGLGLMAGASHRVVTETSRIAMPEVTI
GLYPDVGGSYFLNRMQGKMGLFLGLTAYQLNAADACYVGLADHYLNRDDKELMFDAMATLDWSDTPALNHQRLDSMINEL
SNQVDIPKGESVLADSQDNIDRLMAGSLEDIVTRMSTLASEDAWLMKARDTFLAGSPISWHLVNIQSQLGTKLSLAECFK
WELTASVNVCAHGDFCEGVRALLIDKDRQPQWRFKDVNSVPTAVLEQILTSPWGEAHPFSQLS

Sequences:

>Translated_383_residues
MTNVVDNVNQATTTQNVVFQTLATASGKLIGVVTLNVEKALNALDLDMVRAMTAQLNLWKKDSLVACIVLDGSGEKAFCA
GGDVRALYHASIAAKGQVTEEAKVFFEEEYRLDYLLHTFGKPVLVWGDGIVMGGGLGLMAGASHRVVTETSRIAMPEVTI
GLYPDVGGSYFLNRMQGKMGLFLGLTAYQLNAADACYVGLADHYLNRDDKELMFDAMATLDWSDTPALNHQRLDSMINEL
SNQVDIPKGESVLADSQDNIDRLMAGSLEDIVTRMSTLASEDAWLMKARDTFLAGSPISWHLVNIQSQLGTKLSLAECFK
WELTASVNVCAHGDFCEGVRALLIDKDRQPQWRFKDVNSVPTAVLEQILTSPWGEAHPFSQLS
>Mature_382_residues
TNVVDNVNQATTTQNVVFQTLATASGKLIGVVTLNVEKALNALDLDMVRAMTAQLNLWKKDSLVACIVLDGSGEKAFCAG
GDVRALYHASIAAKGQVTEEAKVFFEEEYRLDYLLHTFGKPVLVWGDGIVMGGGLGLMAGASHRVVTETSRIAMPEVTIG
LYPDVGGSYFLNRMQGKMGLFLGLTAYQLNAADACYVGLADHYLNRDDKELMFDAMATLDWSDTPALNHQRLDSMINELS
NQVDIPKGESVLADSQDNIDRLMAGSLEDIVTRMSTLASEDAWLMKARDTFLAGSPISWHLVNIQSQLGTKLSLAECFKW
ELTASVNVCAHGDFCEGVRALLIDKDRQPQWRFKDVNSVPTAVLEQILTSPWGEAHPFSQLS

Specific function: Unknown

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=333, Percent_Identity=37.5375375375375, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI37594469, Length=298, Percent_Identity=35.9060402684564, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI194097323, Length=177, Percent_Identity=31.638418079096, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25144160, Length=341, Percent_Identity=39.0029325513196, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI25144157, Length=365, Percent_Identity=37.5342465753425, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI25145438, Length=183, Percent_Identity=30.6010928961749, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=355, Percent_Identity=31.2676056338028, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28571729, Length=333, Percent_Identity=40.5405405405405, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI28571730, Length=333, Percent_Identity=40.5405405405405, Blast_Score=227, Evalue=8e-60,
Organism=Drosophila melanogaster, GI20129971, Length=197, Percent_Identity=27.9187817258883, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24653477, Length=197, Percent_Identity=27.9187817258883, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24653139, Length=183, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: 4.2.1.17

Molecular weight: Translated: 41886; Mature: 41755

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVVDNVNQATTTQNVVFQTLATASGKLIGVVTLNVEKALNALDLDMVRAMTAQLNLWK
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCC
KDSLVACIVLDGSGEKAFCAGGDVRALYHASIAAKGQVTEEAKVFFEEEYRLDYLLHTFG
CCCEEEEEEEECCCCEEEECCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
KPVLVWGDGIVMGGGLGLMAGASHRVVTETSRIAMPEVTIGLYPDVGGSYFLNRMQGKMG
CEEEEECCCEEEECCCHHHCCCCCEEEECCCCEECCEEEEEECCCCCHHHHHHHHCCCCE
LFLGLTAYQLNAADACYVGLADHYLNRDDKELMFDAMATLDWSDTPALNHQRLDSMINEL
EEEEEEEEEECCCCEEEEEHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
SNQVDIPKGESVLADSQDNIDRLMAGSLEDIVTRMSTLASEDAWLMKARDTFLAGSPISW
HHCCCCCCCCCEECCCCCCHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCEECCCCCEE
HLVNIQSQLGTKLSLAECFKWELTASVNVCAHGDFCEGVRALLIDKDRQPQWRFKDVNSV
EEEEEHHHCCCCCCHHHHHEEEEEEEEEEEECCCHHHHHHHHEECCCCCCCCCCCCCCCC
PTAVLEQILTSPWGEAHPFSQLS
HHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TNVVDNVNQATTTQNVVFQTLATASGKLIGVVTLNVEKALNALDLDMVRAMTAQLNLWK
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCC
KDSLVACIVLDGSGEKAFCAGGDVRALYHASIAAKGQVTEEAKVFFEEEYRLDYLLHTFG
CCCEEEEEEEECCCCEEEECCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
KPVLVWGDGIVMGGGLGLMAGASHRVVTETSRIAMPEVTIGLYPDVGGSYFLNRMQGKMG
CEEEEECCCEEEECCCHHHCCCCCEEEECCCCEECCEEEEEECCCCCHHHHHHHHCCCCE
LFLGLTAYQLNAADACYVGLADHYLNRDDKELMFDAMATLDWSDTPALNHQRLDSMINEL
EEEEEEEEEECCCCEEEEEHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
SNQVDIPKGESVLADSQDNIDRLMAGSLEDIVTRMSTLASEDAWLMKARDTFLAGSPISW
HHCCCCCCCCCEECCCCCCHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCEECCCCCEE
HLVNIQSQLGTKLSLAECFKWELTASVNVCAHGDFCEGVRALLIDKDRQPQWRFKDVNSV
EEEEEHHHCCCCCCHHHHHEEEEEEEEEEEECCCHHHHHHHHEECCCCCCCCCCCCCCCC
PTAVLEQILTSPWGEAHPFSQLS
HHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3S)-3-hydroxyacyl-CoA

Specific reaction: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]