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The map label for this gene is atoB [H]

Identifier: 126173733

GI number: 126173733

Start: 1738181

End: 1739371

Strand: Direct

Name: atoB [H]

Synonym: Sbal_1495

Alternate gene names: 126173733

Gene position: 1738181-1739371 (Clockwise)

Preceding gene: 126173731

Following gene: 126173734

Centisome position: 33.9

GC content: 52.23

Gene sequence:

>1191_bases
ATGAGTACTGAACAGTTAAATCAAGATATCGTTATTGTTGCTGCTAAACGCACCCCAATGGGCGGGTTTCAAGGCAACTT
ATCATCCGTAGCATCACCCATGTTAGCCGCGACGGCCATTAAAGGCTTGTTAGCGGAAACACAATTGGCGGGTGAGCATG
TTGATGAAGTCTTGATGGGCTGCGTATTACCCGCAGGCTTAGGTCAAGCGCCTGCGCGTCAGGCAACTTTGGGTGCGGGA
TTACCCTTATCCGTTGGTGCGACCACAGTGAACAAGGTCTGTGGCTCAGGCATGAAGACGGTAATGTTAGCCCACGATTT
GATTAAAGCGGGCAGTGCAAAAGTGGTGATCGCAGGCGGCATGGAAAGTATGAGCCAAGCGCCGTATTTACTCGACAAAG
CCCGCGGCGGTATGCGCATGGGCCATGGAAAAGTGTTAGATCACATGTTTTTAGATGGTCTTGAAGATGCCTACACGGGT
GGTGCTATGGGAACGTTTGCCCAGAAAACGGCCGATGAATTTGGTATCACCCGCGAGCAGATGGACGCTTTTGCCTTAAG
CTCGCTTGAAAAAGCCAATGCCGCGATTAACTCGGGTGCCTTTAAAACCGAAATCACGCCCGTCACAGTCAGTGATCGTC
GTGGTGATGTGACTATCGATACCGACGAGCAACCCGGTAATGCCCGCCCTGAAAAAATTCCTACACTGCGCCCAGCCTTT
ACTAAAGATGGCACTATCACAGCGGCAAACTCTAGCTCTATTTCCGATGGCGCAGCGGCATTAATGCTGACCTCACGCGG
CGAAGCTGACCGTTTAGGCTTAGCCGTGTTAGCCACCATTAAAGGCCACACGACTCACGCCCAAGAGCCTTCATTGTTCA
CCACTGCACCGGTTGGCGCTATGGCGAAATTGCTGGCCAATGTCGGTTGGTCAACGGACGAGGTGGATTTATTCGAAATC
AACGAAGCCTTCGCGATGGTGACTATGCTTGCCGTGTCTGAGCTAGGTTTAGATATCGCTAAGGTTAACGTCAATGGCGG
CGCCTGCGCCTTAGGCCATCCTATTGGTTGCTCAGGTTCACGTTTGCTGGTGACCTTAATTCATGCATTAAAAGCCCGCG
GCCTTAAGCGCGGTGTCGCCTCGCTGTGTATCGGCGGTGGTGAAGCGACGGCGATGGCGATTGAGGTTTAA

Upstream 100 bases:

>100_bases
CTTTACGTTCGCGTAAACGTCAGAGTGGTTTTATTGTCGATTTTATTAAACGTCCCGAGGCTGGTACTAGGCTTCGTGGT
CAATTTAGGTTGGAGCCTTC

Downstream 100 bases:

>100_bases
TCGCAAAGGTTTTTGTCAAATCAGGTTTTAGTTAAATCAACAAGACGGGGCAGGCAAGGGCAATCACTTCCCTTGAGGAT
AATCATAATATCGCACCGCC

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSTEQLNQDIVIVAAKRTPMGGFQGNLSSVASPMLAATAIKGLLAETQLAGEHVDEVLMGCVLPAGLGQAPARQATLGAG
LPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSAKVVIAGGMESMSQAPYLLDKARGGMRMGHGKVLDHMFLDGLEDAYTG
GAMGTFAQKTADEFGITREQMDAFALSSLEKANAAINSGAFKTEITPVTVSDRRGDVTIDTDEQPGNARPEKIPTLRPAF
TKDGTITAANSSSISDGAAALMLTSRGEADRLGLAVLATIKGHTTHAQEPSLFTTAPVGAMAKLLANVGWSTDEVDLFEI
NEAFAMVTMLAVSELGLDIAKVNVNGGACALGHPIGCSGSRLLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV

Sequences:

>Translated_396_residues
MSTEQLNQDIVIVAAKRTPMGGFQGNLSSVASPMLAATAIKGLLAETQLAGEHVDEVLMGCVLPAGLGQAPARQATLGAG
LPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSAKVVIAGGMESMSQAPYLLDKARGGMRMGHGKVLDHMFLDGLEDAYTG
GAMGTFAQKTADEFGITREQMDAFALSSLEKANAAINSGAFKTEITPVTVSDRRGDVTIDTDEQPGNARPEKIPTLRPAF
TKDGTITAANSSSISDGAAALMLTSRGEADRLGLAVLATIKGHTTHAQEPSLFTTAPVGAMAKLLANVGWSTDEVDLFEI
NEAFAMVTMLAVSELGLDIAKVNVNGGACALGHPIGCSGSRLLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV
>Mature_395_residues
STEQLNQDIVIVAAKRTPMGGFQGNLSSVASPMLAATAIKGLLAETQLAGEHVDEVLMGCVLPAGLGQAPARQATLGAGL
PLSVGATTVNKVCGSGMKTVMLAHDLIKAGSAKVVIAGGMESMSQAPYLLDKARGGMRMGHGKVLDHMFLDGLEDAYTGG
AMGTFAQKTADEFGITREQMDAFALSSLEKANAAINSGAFKTEITPVTVSDRRGDVTIDTDEQPGNARPEKIPTLRPAFT
KDGTITAANSSSISDGAAALMLTSRGEADRLGLAVLATIKGHTTHAQEPSLFTTAPVGAMAKLLANVGWSTDEVDLFEIN
EAFAMVTMLAVSELGLDIAKVNVNGGACALGHPIGCSGSRLLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=389, Percent_Identity=45.5012853470437, Blast_Score=323, Evalue=2e-88,
Organism=Homo sapiens, GI4557237, Length=390, Percent_Identity=44.3589743589744, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI167614485, Length=391, Percent_Identity=38.618925831202, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI4501853, Length=406, Percent_Identity=36.9458128078818, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4504327, Length=423, Percent_Identity=29.7872340425532, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI194353979, Length=398, Percent_Identity=29.8994974874372, Blast_Score=129, Evalue=5e-30,
Organism=Escherichia coli, GI87082165, Length=389, Percent_Identity=46.7866323907455, Blast_Score=344, Evalue=7e-96,
Organism=Escherichia coli, GI1788554, Length=390, Percent_Identity=51.2820512820513, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1787663, Length=393, Percent_Identity=39.440203562341, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI48994986, Length=404, Percent_Identity=38.1188118811881, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1788683, Length=402, Percent_Identity=28.3582089552239, Blast_Score=142, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25147385, Length=389, Percent_Identity=43.1876606683805, Blast_Score=305, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17535921, Length=391, Percent_Identity=40.153452685422, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI133906874, Length=387, Percent_Identity=36.6925064599483, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17535917, Length=393, Percent_Identity=33.8422391857506, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17551802, Length=426, Percent_Identity=30.5164319248826, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6325229, Length=396, Percent_Identity=47.2222222222222, Blast_Score=335, Evalue=1e-92,
Organism=Saccharomyces cerevisiae, GI6322031, Length=391, Percent_Identity=35.2941176470588, Blast_Score=204, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24655093, Length=388, Percent_Identity=46.9072164948454, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI24640423, Length=389, Percent_Identity=43.4447300771208, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI17648125, Length=395, Percent_Identity=37.2151898734177, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI17137578, Length=427, Percent_Identity=31.1475409836066, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40630; Mature: 40499

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00098 THIOLASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEQLNQDIVIVAAKRTPMGGFQGNLSSVASPMLAATAIKGLLAETQLAGEHVDEVLMG
CCHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CVLPAGLGQAPARQATLGAGLPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSAKVVIAGG
HHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECC
MESMSQAPYLLDKARGGMRMGHGKVLDHMFLDGLEDAYTGGAMGTFAQKTADEFGITREQ
HHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHCCCHHH
MDAFALSSLEKANAAINSGAFKTEITPVTVSDRRGDVTIDTDEQPGNARPEKIPTLRPAF
HHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCC
TKDGTITAANSSSISDGAAALMLTSRGEADRLGLAVLATIKGHTTHAQEPSLFTTAPVGA
CCCCEEEECCCCCCCCCCEEEEEECCCCCHHHCEEEEEEECCCCCCCCCCCCEEECCHHH
MAKLLANVGWSTDEVDLFEINEAFAMVTMLAVSELGLDIAKVNVNGGACALGHPIGCSGS
HHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCCCCCCCCC
RLLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV
HHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEC
>Mature Secondary Structure 
STEQLNQDIVIVAAKRTPMGGFQGNLSSVASPMLAATAIKGLLAETQLAGEHVDEVLMG
CHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CVLPAGLGQAPARQATLGAGLPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSAKVVIAGG
HHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECC
MESMSQAPYLLDKARGGMRMGHGKVLDHMFLDGLEDAYTGGAMGTFAQKTADEFGITREQ
HHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHCCCHHH
MDAFALSSLEKANAAINSGAFKTEITPVTVSDRRGDVTIDTDEQPGNARPEKIPTLRPAF
HHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCC
TKDGTITAANSSSISDGAAALMLTSRGEADRLGLAVLATIKGHTTHAQEPSLFTTAPVGA
CCCCEEEECCCCCCCCCCEEEEEECCCCCHHHCEEEEEEECCCCCCCCCCCCEEECCHHH
MAKLLANVGWSTDEVDLFEINEAFAMVTMLAVSELGLDIAKVNVNGGACALGHPIGCSGS
HHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCCCCCCCCC
RLLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV
HHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]