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The map label for this gene is yaeL [C]

Identifier: 126173695

GI number: 126173695

Start: 1689025

End: 1690395

Strand: Direct

Name: yaeL [C]

Synonym: Sbal_1457

Alternate gene names: 126173695

Gene position: 1689025-1690395 (Clockwise)

Preceding gene: 126173694

Following gene: 126173696

Centisome position: 32.94

GC content: 48.07

Gene sequence:

>1371_bases
ATGTTAGATTTTTTATGGAACTTAGGTTCTTTCATCGTTGCACTGGGCCTGTTAATCACCGCCCACGAATACGGCCATTT
CTATGTCGCACGCCGTTGTGGTGTCAAAGTCGAACGTTTCTCCATTGGTTTCGGTAAGGCGATTTGGCGCCGTGTCGGTA
AAGACGGCACTGAATACGTGTTAGCCATGATCCCACTCGGTGGCTATGTCAAAATGCTCGATGAGCGCGTCGAAGACGTC
CCAGAAGCATTAAAAGATCAAGCATTCAATCGTAAAACCGTATGGCAGCGCATTGCGATTGTGGCTGCTGGCCCGATTGC
GAATTTTATTTTTGCCATCGTTGCCTTGTATTTTATGTATCTGATTGGTGTGCCATCACTGAAACCTGTGATCACATCGA
CAACACCTGGGACTGCCGCCGCGCAAATCCAGGTCACAGAGCCCATGCAAATAACGGCCATTTCCGGCCAGGCTGTGCGT
AACTGGGAAGAAGTGAATTTAGCCTTAGTGGGCCACATAGGCGATGAAAGCCTGAGTCTATCGCTGACGCCATTGAGCGG
TTTGCAGGGCTTAGATTCCAGCGCGCGCTCTTATACCTTAGATACCAGCAATTGGCATTTTGATCCTGAAAAAGAATCGC
CGATTACCACCTTAGGTTTAGGGATATATCGCCCCGAAATCGACCCTACAATTGCTGCTATTAGCCCTGACAGCGCCGCT
GCCAAAAGCGAGCTGAAAGTCGGCGATACCTTAGTGGCGATAAATGGTAAAAATTATACCGATTGGCAGGCTTTTGTTGA
CATTATTCAACATTCTGCCAATGTGCCTGTGAGCTTAACTGTGCGTCGTAATGGCGAACAGTTTAACGTGGCAGTGACAC
CGTTAAGCAGCAAAAGCGCCGATGGCCAAGAGATAGGTATGCTGGGGGTGAGCCCAACCCAAGCGCCATGGCCAGACAAT
ATGCGTTTACAACTTGAATATGGACCAATCGATTCTTTCGGCATCGCAGCGGATAAAACATGGCAACTTGTTGCTGTGAG
CTTTAAGATGATTGGCAAATTATTTACCGGCGATGTGTCGGTGAAAAACCTGAGTGGACCCATCTCGATCGCACAGGGTG
CGGGCAGTAGTGCAAACTATGGCTTGGTCTATTTTCTCGGGTTCCTCGCGCTCATCAGCGTCAATTTAGGCATCATTAAC
TTGTTGCCTTTACCTGTGCTCGATGGGGGACACCTGCTGTATTACTTTATTGAAGTAATAACTGGTAAACCTGTACCTGA
AAAGGTGCAGGAAATAGGATTCAGATTTGGGGCAGCAATACTGCTGATGTTGATGAGCATTGCGCTTTTCAATGATTTTG
CCCGACTCTGA

Upstream 100 bases:

>100_bases
TTTAGCCTTAGATGCGCAAACCCGGGTCTATGCGCGTGAGACCTTAGCAAGCATCGCTTAGCAATGGCTGAGTGATTAAA
TCAATGACGTAAGGAGTGGG

Downstream 100 bases:

>100_bases
GCAAGGACAGACTAATAATTAGAAGTGCTCTATGAGATTGAATAAACTTTTTGCCTCGATGTTATTCGTCGGTGCGTCGT
TTTCAGGGACTGTGTTGGCT

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MLDFLWNLGSFIVALGLLITAHEYGHFYVARRCGVKVERFSIGFGKAIWRRVGKDGTEYVLAMIPLGGYVKMLDERVEDV
PEALKDQAFNRKTVWQRIAIVAAGPIANFIFAIVALYFMYLIGVPSLKPVITSTTPGTAAAQIQVTEPMQITAISGQAVR
NWEEVNLALVGHIGDESLSLSLTPLSGLQGLDSSARSYTLDTSNWHFDPEKESPITTLGLGIYRPEIDPTIAAISPDSAA
AKSELKVGDTLVAINGKNYTDWQAFVDIIQHSANVPVSLTVRRNGEQFNVAVTPLSSKSADGQEIGMLGVSPTQAPWPDN
MRLQLEYGPIDSFGIAADKTWQLVAVSFKMIGKLFTGDVSVKNLSGPISIAQGAGSSANYGLVYFLGFLALISVNLGIIN
LLPLPVLDGGHLLYYFIEVITGKPVPEKVQEIGFRFGAAILLMLMSIALFNDFARL

Sequences:

>Translated_456_residues
MLDFLWNLGSFIVALGLLITAHEYGHFYVARRCGVKVERFSIGFGKAIWRRVGKDGTEYVLAMIPLGGYVKMLDERVEDV
PEALKDQAFNRKTVWQRIAIVAAGPIANFIFAIVALYFMYLIGVPSLKPVITSTTPGTAAAQIQVTEPMQITAISGQAVR
NWEEVNLALVGHIGDESLSLSLTPLSGLQGLDSSARSYTLDTSNWHFDPEKESPITTLGLGIYRPEIDPTIAAISPDSAA
AKSELKVGDTLVAINGKNYTDWQAFVDIIQHSANVPVSLTVRRNGEQFNVAVTPLSSKSADGQEIGMLGVSPTQAPWPDN
MRLQLEYGPIDSFGIAADKTWQLVAVSFKMIGKLFTGDVSVKNLSGPISIAQGAGSSANYGLVYFLGFLALISVNLGIIN
LLPLPVLDGGHLLYYFIEVITGKPVPEKVQEIGFRFGAAILLMLMSIALFNDFARL
>Mature_456_residues
MLDFLWNLGSFIVALGLLITAHEYGHFYVARRCGVKVERFSIGFGKAIWRRVGKDGTEYVLAMIPLGGYVKMLDERVEDV
PEALKDQAFNRKTVWQRIAIVAAGPIANFIFAIVALYFMYLIGVPSLKPVITSTTPGTAAAQIQVTEPMQITAISGQAVR
NWEEVNLALVGHIGDESLSLSLTPLSGLQGLDSSARSYTLDTSNWHFDPEKESPITTLGLGIYRPEIDPTIAAISPDSAA
AKSELKVGDTLVAINGKNYTDWQAFVDIIQHSANVPVSLTVRRNGEQFNVAVTPLSSKSADGQEIGMLGVSPTQAPWPDN
MRLQLEYGPIDSFGIAADKTWQLVAVSFKMIGKLFTGDVSVKNLSGPISIAQGAGSSANYGLVYFLGFLALISVNLGIIN
LLPLPVLDGGHLLYYFIEVITGKPVPEKVQEIGFRFGAAILLMLMSIALFNDFARL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=456, Percent_Identity=51.0964912280702, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49457; Mature: 49457

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFLWNLGSFIVALGLLITAHEYGHFYVARRCGVKVERFSIGFGKAIWRRVGKDGTEYV
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCEEEEEECCHHHHHHHHHCCCCCCEE
LAMIPLGGYVKMLDERVEDVPEALKDQAFNRKTVWQRIAIVAAGPIANFIFAIVALYFMY
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHH
LIGVPSLKPVITSTTPGTAAAQIQVTEPMQITAISGQAVRNWEEVNLALVGHIGDESLSL
HHCCCCCCCEEECCCCCCEEEEEEEECCEEEEEECCHHHCCHHHEEEEEEEEECCCCEEE
SLTPLSGLQGLDSSARSYTLDTSNWHFDPEKESPITTLGLGIYRPEIDPTIAAISPDSAA
EECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECEEECCCCCCEEEEECCCCHH
AKSELKVGDTLVAINGKNYTDWQAFVDIIQHSANVPVSLTVRRNGEQFNVAVTPLSSKSA
HHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCCC
DGQEIGMLGVSPTQAPWPDNMRLQLEYGPIDSFGIAADKTWQLVAVSFKMIGKLFTGDVS
CCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
VKNLSGPISIAQGAGSSANYGLVYFLGFLALISVNLGIINLLPLPVLDGGHLLYYFIEVI
EECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEECCCHHHHHHHHHH
TGKPVPEKVQEIGFRFGAAILLMLMSIALFNDFARL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDFLWNLGSFIVALGLLITAHEYGHFYVARRCGVKVERFSIGFGKAIWRRVGKDGTEYV
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCEEEEEECCHHHHHHHHHCCCCCCEE
LAMIPLGGYVKMLDERVEDVPEALKDQAFNRKTVWQRIAIVAAGPIANFIFAIVALYFMY
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHH
LIGVPSLKPVITSTTPGTAAAQIQVTEPMQITAISGQAVRNWEEVNLALVGHIGDESLSL
HHCCCCCCCEEECCCCCCEEEEEEEECCEEEEEECCHHHCCHHHEEEEEEEEECCCCEEE
SLTPLSGLQGLDSSARSYTLDTSNWHFDPEKESPITTLGLGIYRPEIDPTIAAISPDSAA
EECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECEEECCCCCCEEEEECCCCHH
AKSELKVGDTLVAINGKNYTDWQAFVDIIQHSANVPVSLTVRRNGEQFNVAVTPLSSKSA
HHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCCC
DGQEIGMLGVSPTQAPWPDNMRLQLEYGPIDSFGIAADKTWQLVAVSFKMIGKLFTGDVS
CCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
VKNLSGPISIAQGAGSSANYGLVYFLGFLALISVNLGIINLLPLPVLDGGHLLYYFIEVI
EECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEECCCHHHHHHHHHH
TGKPVPEKVQEIGFRFGAAILLMLMSIALFNDFARL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]