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The map label for this gene is ptsG [H]

Identifier: 126173682

GI number: 126173682

Start: 1673566

End: 1675053

Strand: Direct

Name: ptsG [H]

Synonym: Sbal_1444

Alternate gene names: 126173682

Gene position: 1673566-1675053 (Clockwise)

Preceding gene: 126173681

Following gene: 126173683

Centisome position: 32.64

GC content: 50.07

Gene sequence:

>1488_bases
ATGGCTAGAACGCTGGAATCAAGTCGTCAAAACCGAGCTCGTCGCTTAGGCAGTTTCGTTACTCAGCAGTGGTTTAAATT
TGCCCAGCGCTTAAGCCAAGCGCTGCTTATTCCTATTGCCATTTTACCTGCCGCAGGGGTCATGCTTGGCCTCACCGTTA
GTCCTATTCCTTTTATGCCCGAAGAGCTGACAGTGTTGATGTTGGCGGTGGGCAAACTCATTTTCGCCATCATGCCGATG
TTATTTGCCGTGGCGGTCGCTATTGGCTTTTGCCGCGATCAAGGCATTGCCGCCTTTACGGCGGTGTTTGGTTATGGGGT
GATGACGGCGACATTAGCCGCACTGGCCGATTTATATCGACTCCCAACCCAGCCTTTATTGGGGATGGATACCTTAGATA
CGGGGATTGCGGGTGGCATGATGCTCGGCGGTATTACTTGTCTTGCGGTGCGCTGGAGTCAATATATACGTTTGCCTGCG
ATTTTCTCCTTCTTTGAGGGACGTCGCAGTGCATCTTTGCTGATCATTCCCCTAGCGATGGGCTTAGGTTATGTGCTCGC
CCATGTGTGGCCACCCTTAGCGCTATTGATTGAGCGGGTATCTGACTGGGCGGTTTATCAAAAACCGGCCATTGCTTTTG
GCGTGTATGGCGCGCTAGAGCGGTTACTTATTCCCCTTGGGTTGCACCATATTTGGAACGCGCCTTTTTACTTAGAAGTG
GGTCAATATCAGTTATTAGGGCATGAAGTCGTCCGTGGTGAGGTGGCGCGTTATTTAGCGGGCGATCCGCAGGCGGGAAA
CCTTGCTGGTGGTTACCTGATTAAAATGTGGGGATTACCTGCGGCGGCGCTGGCAATGTGGCGCTGCGCCGATCCTTCTG
AGCGTAATCGCGTGGCGGGTATTATGCTCTCGGCAGGTGCGGCAAGTTGGTTAACTGGGGTGACTGAACCTATTGAATTT
GCCTTTATGTTTGTGGCGCCAATCCTATTTATCATTCACGCCTTACTCACTGGGCTCGCTTATTTTGTCTGTATTATGCT
CGATATTCACCACAGCATAGTGTTCTCACAAGGGCTGGTGGACTTTACGTTGTTATTTCCATTGTCCCGTAATGCCAGCT
GGTTTATTTTCCTCGGGCCTTTAACTGCTATAATATATTACCTGTTGTTTAGACTGAGTATTTTAGCCTTTAATTTGAAA
ACGCCCGGCAGGCTTGAGCATAACGACAGTGACAGTAAAGGACCTAAAGAAAGTTTACGGGCGATTATTGCGGCGCTTGG
CGGGCGTGACAATATCGTTGAGCTGAATGCTTGTTTGACACGGTTACGCTTGAGCGTACACAAGCCAGAGTTAGTCAATA
AGGTGCGTTTGAGTCAGTTGGGTGCTAAGGGCGTGATCGTTATGGGCAAAGGTGTGCAGGTGGTTTATGGCACTAAGGCC
GAAACCCTGCGTAAAGTATTGCAGCGTTACTTAGATACTCGCCGCTAG

Upstream 100 bases:

>100_bases
CTGTAGATGTGCTCTTGAGTGAACTTGGCGCTAAACCACTTGTAGAATTATTAGAAATCGATGCCTGTGAAACCATGGAA
CCTGAGGTTGAAGCGATAAA

Downstream 100 bases:

>100_bases
GATTGTGTTTTTACAAAATTAACTGCTTAATTTTTACATTTTATTGATTCAAGCCTCTGAAATGTCATTTTTATTTTCGC
ATTATAGGATTTTCATGCTG

Product: PTS system, glucose-like IIB subunit

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MARTLESSRQNRARRLGSFVTQQWFKFAQRLSQALLIPIAILPAAGVMLGLTVSPIPFMPEELTVLMLAVGKLIFAIMPM
LFAVAVAIGFCRDQGIAAFTAVFGYGVMTATLAALADLYRLPTQPLLGMDTLDTGIAGGMMLGGITCLAVRWSQYIRLPA
IFSFFEGRRSASLLIIPLAMGLGYVLAHVWPPLALLIERVSDWAVYQKPAIAFGVYGALERLLIPLGLHHIWNAPFYLEV
GQYQLLGHEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPAAALAMWRCADPSERNRVAGIMLSAGAASWLTGVTEPIEF
AFMFVAPILFIIHALLTGLAYFVCIMLDIHHSIVFSQGLVDFTLLFPLSRNASWFIFLGPLTAIIYYLLFRLSILAFNLK
TPGRLEHNDSDSKGPKESLRAIIAALGGRDNIVELNACLTRLRLSVHKPELVNKVRLSQLGAKGVIVMGKGVQVVYGTKA
ETLRKVLQRYLDTRR

Sequences:

>Translated_495_residues
MARTLESSRQNRARRLGSFVTQQWFKFAQRLSQALLIPIAILPAAGVMLGLTVSPIPFMPEELTVLMLAVGKLIFAIMPM
LFAVAVAIGFCRDQGIAAFTAVFGYGVMTATLAALADLYRLPTQPLLGMDTLDTGIAGGMMLGGITCLAVRWSQYIRLPA
IFSFFEGRRSASLLIIPLAMGLGYVLAHVWPPLALLIERVSDWAVYQKPAIAFGVYGALERLLIPLGLHHIWNAPFYLEV
GQYQLLGHEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPAAALAMWRCADPSERNRVAGIMLSAGAASWLTGVTEPIEF
AFMFVAPILFIIHALLTGLAYFVCIMLDIHHSIVFSQGLVDFTLLFPLSRNASWFIFLGPLTAIIYYLLFRLSILAFNLK
TPGRLEHNDSDSKGPKESLRAIIAALGGRDNIVELNACLTRLRLSVHKPELVNKVRLSQLGAKGVIVMGKGVQVVYGTKA
ETLRKVLQRYLDTRR
>Mature_494_residues
ARTLESSRQNRARRLGSFVTQQWFKFAQRLSQALLIPIAILPAAGVMLGLTVSPIPFMPEELTVLMLAVGKLIFAIMPML
FAVAVAIGFCRDQGIAAFTAVFGYGVMTATLAALADLYRLPTQPLLGMDTLDTGIAGGMMLGGITCLAVRWSQYIRLPAI
FSFFEGRRSASLLIIPLAMGLGYVLAHVWPPLALLIERVSDWAVYQKPAIAFGVYGALERLLIPLGLHHIWNAPFYLEVG
QYQLLGHEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPAAALAMWRCADPSERNRVAGIMLSAGAASWLTGVTEPIEFA
FMFVAPILFIIHALLTGLAYFVCIMLDIHHSIVFSQGLVDFTLLFPLSRNASWFIFLGPLTAIIYYLLFRLSILAFNLKT
PGRLEHNDSDSKGPKESLRAIIAALGGRDNIVELNACLTRLRLSVHKPELVNKVRLSQLGAKGVIVMGKGVQVVYGTKAE
TLRKVLQRYLDTRR

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=472, Percent_Identity=43.6440677966102, Blast_Score=425, Evalue=1e-120,
Organism=Escherichia coli, GI1786894, Length=487, Percent_Identity=36.5503080082135, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1787908, Length=523, Percent_Identity=34.0344168260038, Blast_Score=228, Evalue=7e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 54315; Mature: 54184

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTLESSRQNRARRLGSFVTQQWFKFAQRLSQALLIPIAILPAAGVMLGLTVSPIPFMP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
EELTVLMLAVGKLIFAIMPMLFAVAVAIGFCRDQGIAAFTAVFGYGVMTATLAALADLYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LPTQPLLGMDTLDTGIAGGMMLGGITCLAVRWSQYIRLPAIFSFFEGRRSASLLIIPLAM
CCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHH
GLGYVLAHVWPPLALLIERVSDWAVYQKPAIAFGVYGALERLLIPLGLHHIWNAPFYLEV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GQYQLLGHEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPAAALAMWRCADPSERNRVAG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCCCHHHHHHHHCCCCCCCCCHHH
IMLSAGAASWLTGVTEPIEFAFMFVAPILFIIHALLTGLAYFVCIMLDIHHSIVFSQGLV
EEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DFTLLFPLSRNASWFIFLGPLTAIIYYLLFRLSILAFNLKTPGRLEHNDSDSKGPKESLR
HHHHEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
AIIAALGGRDNIVELNACLTRLRLSVHKPELVNKVRLSQLGAKGVIVMGKGVQVVYGTKA
HHHHHHCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCCH
ETLRKVLQRYLDTRR
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARTLESSRQNRARRLGSFVTQQWFKFAQRLSQALLIPIAILPAAGVMLGLTVSPIPFMP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
EELTVLMLAVGKLIFAIMPMLFAVAVAIGFCRDQGIAAFTAVFGYGVMTATLAALADLYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LPTQPLLGMDTLDTGIAGGMMLGGITCLAVRWSQYIRLPAIFSFFEGRRSASLLIIPLAM
CCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHH
GLGYVLAHVWPPLALLIERVSDWAVYQKPAIAFGVYGALERLLIPLGLHHIWNAPFYLEV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GQYQLLGHEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPAAALAMWRCADPSERNRVAG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCCCHHHHHHHHCCCCCCCCCHHH
IMLSAGAASWLTGVTEPIEFAFMFVAPILFIIHALLTGLAYFVCIMLDIHHSIVFSQGLV
EEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DFTLLFPLSRNASWFIFLGPLTAIIYYLLFRLSILAFNLKTPGRLEHNDSDSKGPKESLR
HHHHEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
AIIAALGGRDNIVELNACLTRLRLSVHKPELVNKVRLSQLGAKGVIVMGKGVQVVYGTKA
HHHHHHCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCCH
ETLRKVLQRYLDTRR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]